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公开(公告)号:US20110202480A1
公开(公告)日:2011-08-18
申请号:US13060450
申请日:2009-09-04
摘要: Methods of developing equations for objectively assigning or predicting an apparent age are disclosed. Advantageously, the equations of objective apparent age may be based on a relatively small number of critical parameters combined in a way that accounts for all or most of the apparent skin aging in a defined population or sub-population. Despite the relatively small data collection requirements, the present invention includes an objective model of apparent age that is useful for evaluation of products, useful for predicting treatment outcomes and useful for predicting the effects of deteriorative factors. The formalization of an Objective Apparent Age Score allows one to identify the biophysical and biochemical parameters that mostly influence an individual's apparent age, and can be used to select specific anti-aging treatments with increased chances of visible success. The Objective Apparent Age Score may also be used to support marketing claims.
摘要翻译: 公开了客观分配或预测表观年龄的方程的方法。 有利地,客观表观年龄的方程可以基于相对较少数量的关键参数,其组合方式考虑了定义的群体或子群体中的所有或大部分明显的皮肤老化。 尽管数据收集要求相对较小,但是本发明包括可用于评估产品的明显年龄的客观模型,对预测治疗结果有用,并且可用于预测恶化因素的影响。 客观表观年龄分数的形式化允许人们识别主要影响个体表观年龄的生物物理和生物化学参数,并且可以用于选择具有可见成功机会的特定抗衰老治疗。 客观表观年龄分数也可用于支持营销声明。
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公开(公告)号:US08666770B2
公开(公告)日:2014-03-04
申请号:US13060450
申请日:2009-09-04
摘要: Methods of developing equations for objectively assigning or predicting an apparent age are disclosed. Advantageously, the equations of objective apparent age may be based on a relatively small number of critical parameters combined in a way that accounts for all or most of the apparent skin aging in a defined population or sub-population. Despite the relatively small data collection requirements, the present invention includes an objective model of apparent age that is useful for evaluation of products, useful for predicting treatment outcomes and useful for predicting the effects of deteriorative factors. The formalization of an Objective Apparent Age Score allows one to identify the biophysical and biochemical parameters that mostly influence an individual's apparent age, and can be used to select specific anti-aging treatments with increased chances of visible success. The Objective Apparent Age Score may also be used to support marketing claims.
摘要翻译: 公开了客观分配或预测表观年龄的方程的方法。 有利地,客观表观年龄的方程可以基于相对较少数量的关键参数,其组合方式考虑了定义的群体或子群体中的所有或大部分明显的皮肤老化。 尽管数据收集要求相对较小,但是本发明包括可用于评估产品的明显年龄的客观模型,对预测治疗结果有用,并且可用于预测恶化因素的影响。 客观表观年龄分数的形式化允许人们识别主要影响个体表观年龄的生物物理和生物化学参数,并且可以用于选择具有可见成功机会的特定抗衰老治疗。 客观表观年龄分数也可用于支持营销声明。
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公开(公告)号:US09782448B2
公开(公告)日:2017-10-10
申请号:US13957647
申请日:2013-08-02
IPC分类号: A61K36/752 , A61K8/34 , A61K8/49 , A61K8/63 , A61K8/97 , A61Q19/00 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K8/9706
CPC分类号: A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要: A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor.
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公开(公告)号:US20100323042A1
公开(公告)日:2010-12-23
申请号:US12743500
申请日:2008-07-07
IPC分类号: A61K36/736 , A61K36/899 , A61P29/00
CPC分类号: A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要: A method for formulating products to normalize skin or treat irritated or inflamed skin, a method for normalizing skin or treating irritated or inflamed skin for improvement, and compositions therefor.
摘要翻译: 用于配制产品以使皮肤正常化或治疗刺激性或发炎的皮肤的方法,使皮肤正常化或治疗刺激性或发炎皮肤以改善的方法及其组合物。
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公开(公告)号:US6139855A
公开(公告)日:2000-10-31
申请号:US243362
申请日:1999-02-01
申请人: Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
发明人: Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
IPC分类号: A61K8/19 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/46 , A61K33/00 , A61K45/00 , A61K47/02 , A61Q19/00 , C02F1/00 , C02F1/461 , A61K9/10
CPC分类号: C02F1/4618 , A61K33/00 , C02F1/005 , C02F2103/026 , Y10S514/937
摘要: The invention relates to composition having enhanced biological activity, the compositions comprising at least one structured water. In particular, the compositions contain a combination of I and S waters and a biologically active agent, in which the activity of the agent is increased relative to its activity in a non-structured water composition.
摘要翻译: 本发明涉及具有增强的生物活性的组合物,所述组合物包含至少一种结构化水。 特别地,组合物含有I和S水的组合和生物活性剂,其中药物的活性相对于其在非结构化水组合物中的活性而增加。
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公开(公告)号:US20140161898A1
公开(公告)日:2014-06-12
申请号:US13957647
申请日:2013-08-02
IPC分类号: A61K36/752 , A61K31/05 , A61K36/38 , A61K36/28 , A61K31/19 , A61K36/575 , A61K35/56 , A61K36/02
CPC分类号: A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要: A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor.
摘要翻译: 一种用包含至少一种组胺受体途径抑制剂的组合物处理完整的刺激性或发炎皮肤的方法; 至少一种脂氧合酶途径抑制剂; 至少一种环加氧酶途径抑制剂和至少一种趋化性途径抑制剂。
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公开(公告)号:US08535738B2
公开(公告)日:2013-09-17
申请号:US12743500
申请日:2008-07-07
IPC分类号: A61K8/63
CPC分类号: A61K36/752 , A61K8/347 , A61K8/498 , A61K8/63 , A61K8/97 , A61K8/9706 , A61K31/05 , A61K31/19 , A61K35/614 , A61K36/02 , A61K36/28 , A61K36/38 , A61K36/575 , A61K2800/75 , A61Q19/008
摘要: A method for formulating products to normalize skin or treat irritated or inflamed skin, a method for normalizing skin or treating irritated or inflamed skin for improvement, and compositions therefor.
摘要翻译: 用于配制产品以使皮肤正常化或治疗刺激性或发炎的皮肤的方法,使皮肤正常化或治疗刺激性或发炎皮肤以改善的方法及其组合物。
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公开(公告)号:US06680062B2
公开(公告)日:2004-01-20
申请号:US09971561
申请日:2001-10-05
IPC分类号: A61K600
CPC分类号: A61Q19/00 , A61K8/35 , A61K8/368 , A61K8/41 , A61K8/73 , A61K8/97 , A61K8/9706 , A61K8/987 , A61K31/122 , A61K31/203 , A61K31/60 , A61K31/70 , A61K36/82 , A61K2800/59 , A61K2800/75 , Y10S514/887 , A61K2300/00
摘要: The present invention relates to a cosmetic or pharmaceutical composition for topical application to the skin afflicted with rosacea and treated with a retinoid. The composition for treating rosacea comprises an anti-irritating component and several other components for treating rosacea. The other components form a mixture of a salicylic acid, a phytosphingosine, green tea, hinokitiol, gorgonian extract, and polysaccharide. The invention also provides a method for decreasing the irritation on the skin caused by the heightened sensitivity experienced by skin suffering from rosacea. The other components are effective in treating the rosacea condition, but particularly, in treating the telangiectasic symptom of rosacea.
摘要翻译: 本发明涉及用于局部应用于患有红斑痤疮并用类视黄醇治疗的皮肤的化妆品或药物组合物。 用于治疗酒渣鼻的组合物包含用于治疗酒渣鼻的抗刺激成分和若干其它成分。 其他组分形成水杨酸,植物鞘氨醇,绿茶,桧醇,高戈贡提取物和多糖的混合物。 本发明还提供了一种降低由于患有红斑痤疮的皮肤所感受到的敏感性增加引起的皮肤刺激的方法。 其他成分可有效治疗红斑痤疮病症,特别是治疗红斑痤疮的毛细血管扩张症状。
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公开(公告)号:US5503824A
公开(公告)日:1996-04-02
申请号:US164519
申请日:1993-12-09
申请人: Peter Lentini , Kenneth Marenus , Neelam Muizzuddin , Edward Pelle , Louis Punto
发明人: Peter Lentini , Kenneth Marenus , Neelam Muizzuddin , Edward Pelle , Louis Punto
IPC分类号: A61K8/00 , A61K8/34 , A61K8/35 , A61K8/41 , A61K8/64 , A61K8/84 , A61K8/89 , A61K8/898 , A61Q17/04 , A61Q19/04 , C08L83/08 , A61K7/42
摘要: The disclosed invention is directed to methods and compositions for improving the rate, extent and lifetime of an artificially induced tanning of the human skin. The invention entails treating the skin with agents such as amino acids, dipeptides, and amino substituted containing polymers either prior to or simultaneously with application of dihydroxyacetone.
摘要翻译: 所公开的发明涉及用于改善人造皮肤人造鞣制的速率,程度和寿命的方法和组合物。 本发明要求在施用二羟基丙酮之前或同时用诸如氨基酸,二肽和氨基取代的聚合物之类的物质处理皮肤。
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公开(公告)号:US07862822B2
公开(公告)日:2011-01-04
申请号:US11860909
申请日:2007-09-25
IPC分类号: A61K36/06
摘要: The present invention relates to topical skin whitening compositions comprising a whitening effective amount of a black yeast-derived melanin-degrading enzyme extract and a method of preparing the compositions. The compositions provide a whitening effect by degrading melanin on the surface of the skin, the hair and the nails. The enzyme extract can be derived from Exophiala mansonii. The compositions containing the enzyme extract are more effective than are similar compositions containing kojic acid in producing a whitening effect on the skin.
摘要翻译: 本发明涉及包含增白有效量的黑酵母衍生的黑色素降解酶提取物的局部皮肤增白组合物和制备该组合物的方法。 该组合物通过降解皮肤表面,头发和指甲上的黑色素来提供美白效果。 酶提取物可以衍生自洋葱(Exophiala mansonii)。 含有酶提取物的组合物比含有曲酸的类似组合物在皮肤上产生美白效果方面更有效。
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