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公开(公告)号:US07771588B2
公开(公告)日:2010-08-10
申请号:US11443231
申请日:2006-05-30
CPC分类号: C23F11/122 , B01D17/047 , C10G1/04 , C10G33/04
摘要: The invention pertains to the use of a class of acetylenic surfactants to resolve or break water and oil emulsions. The surfactants are of particular advantage in resolving crude oil emulsions of the type encountered in desalter and similar apparatus designed to extract brines from the crude as they partition to the aqueous phase in the desalter. Also, the surfactants may be used to separate oil from oil sands and similar oil/solids matrices.
摘要翻译: 本发明涉及使用一类炔属表面活性剂来分解或破坏水和油乳液。 表面活性剂特别有利于解决在脱盐剂中遇到的类型的原油乳液和类似的装置,其设计用于在脱盐器中分配至水相时从粗品中提取盐水。 此外,表面活性剂可用于将油与油砂和类似的油/固体基质分离。
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公开(公告)号:US07612117B2
公开(公告)日:2009-11-03
申请号:US11281532
申请日:2005-11-17
CPC分类号: C10G33/04
摘要: The invention pertains to the use of a class of acetylenic surfactants to resolve or break water and oil emulsions. The surfactants are of particular advantage in resolving crude oil emulsions of the type encountered in desalter and similar apparatus designed to extract brines from the crude as they partition to the aqueous phase in the desalter.
摘要翻译: 本发明涉及使用一类炔属表面活性剂来分解或破坏水和油乳液。 表面活性剂特别有利于解决在脱盐剂中遇到的类型的原油乳液和类似的装置,其设计用于在脱盐器中分配至水相时从粗品中提取盐水。
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公开(公告)号:US20080264830A1
公开(公告)日:2008-10-30
申请号:US12215340
申请日:2008-06-26
IPC分类号: C10G29/04
摘要: Methods for reducing calcium deposition along surfaces in contact with the water phase of a resolved water/oil emulsion are disclosed. High calcium crude oil and the like are contacted with a sequestrant to form a sequestered calcium containing complex that partitions to the water phase in the resolved emulsion. A specifically formulated polymeric deposit control agent is added to the water phase to inhibit calcium deposit formation therein and along surfaces in contact with the water phase.
摘要翻译: 公开了减少与分解的水/油乳液的水相接触的表面的钙沉积的方法。 高钙原油等与多价螯合剂接触以形成分离在分辨乳液中的水相的螯合的含钙复合物。 向水相中加入特殊配制的聚合物沉积物控制剂,以抑制其中的钙沉积物形成并与水相接触的表面。
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公开(公告)号:US06946467B2
公开(公告)日:2005-09-20
申请号:US10030187
申请日:2001-12-06
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
IPC分类号: C07D295/16 , A61K31/395 , A61K31/445 , A61K31/495 , A61K31/496 , A61K31/497 , A61K31/501 , A61P1/16 , A61P7/02 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P17/02 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/46 , C07D211/58 , C07D213/36 , C07D213/38 , C07D213/56 , C07D213/74 , C07D231/56 , C07D277/64 , C07D295/18 , C07D295/185 , C07D309/14 , C07D309/32 , C07D309/34 , C07D335/02 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D417/12 , C07D417/14 , C07D521/00
CPC分类号: C07D295/185 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/46 , C07D213/36 , C07D213/56 , C07D231/12 , C07D233/56 , C07D249/08 , C07D309/34 , C07D335/02 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要: The compound 1-(indole-6-carbonyl-D-phenylglycinyl)-4-(1-methylpiperidin-4-yl)piperazine and physiologically-tolerable salts thereof are factor Xa inhibitors useful for the treatment of thrombotic disorders.
摘要翻译: 化合物1-(吲哚-6-羰基-D-苯基甘氨酰基)-4-(1-甲基哌啶-4-基)哌嗪及其生理上可耐受的盐是可用于治疗血栓形成障碍的因子Xa抑制剂。
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公开(公告)号:US06936611B2
公开(公告)日:2005-08-30
申请号:US10754923
申请日:2004-01-12
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
IPC分类号: C07D295/16 , A61K31/395 , A61K31/445 , A61K31/495 , A61K31/496 , A61K31/497 , A61K31/501 , A61P1/16 , A61P7/02 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P17/02 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/46 , C07D211/58 , C07D213/36 , C07D213/38 , C07D213/56 , C07D213/74 , C07D231/56 , C07D277/64 , C07D295/18 , C07D295/185 , C07D309/14 , C07D309/32 , C07D309/34 , C07D335/02 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D417/12 , C07D417/14 , C07D521/00
CPC分类号: C07D295/185 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/46 , C07D213/36 , C07D213/56 , C07D231/12 , C07D233/56 , C07D249/08 , C07D309/34 , C07D335/02 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.
摘要翻译: 其中R 2,X,Y,Cy,L和Lp(D)n N具有本说明书中给出的含义的式(I)化合物是 丝氨酸蛋白酶,因子Xa,可用于治疗心血管疾病。
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公开(公告)号:US06900196B2
公开(公告)日:2005-05-31
申请号:US10883715
申请日:2004-07-06
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
IPC分类号: C07D207/12 , C07D211/26 , C07D211/46 , C07D211/58 , C07D211/62 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D417/14 , A61K31/33 , A61K31/445 , C07D209/04 , C07D211/00 , C07D401/00
CPC分类号: C07D401/04 , C07D207/12 , C07D211/26 , C07D211/46 , C07D211/58 , C07D211/62 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.
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公开(公告)号:US07351822B2
公开(公告)日:2008-04-01
申请号:US10803157
申请日:2004-03-18
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson , Peter Robert Guzzo , Michael John Mayer
IPC分类号: C07D401/12 , C07D401/14 , A61K31/496
CPC分类号: C07D295/185 , C07D207/12 , C07D207/14 , C07D211/26 , C07D211/46 , C07D213/36 , C07D213/56 , C07D231/12 , C07D233/56 , C07D249/08 , C07D309/34 , C07D335/02 , C07D401/12 , C07D401/14 , C07D403/12 , C07D409/12 , C07D417/12 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.
摘要翻译: 其中R 2,X,Y,Cy,L和Lp(D)n N具有本说明书中给出的含义的式(I)化合物是 丝氨酸蛋白酶,因子Xa,可用于治疗心血管疾病。
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公开(公告)号:US07053078B2
公开(公告)日:2006-05-30
申请号:US10030188
申请日:2001-06-12
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
IPC分类号: A61K31/33 , A61K31/445 , C07D211/00 , C07D401/00 , C07D209/04
CPC分类号: C07D401/04 , C07D207/12 , C07D211/26 , C07D211/46 , C07D211/58 , C07D211/62 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/12 , C07D409/14 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.
摘要翻译: 其中R 2,X,Y,Cy,L和Lp(D)n N具有本说明书中给出的含义的式(I)化合物是 丝氨酸蛋白酶,因子Xa,可用于治疗心血管疾病。
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公开(公告)号:US06878725B2
公开(公告)日:2005-04-12
申请号:US10030189
申请日:2001-06-12
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
IPC分类号: A61K31/40 , A61K31/4439 , A61K31/445 , A61K31/4545 , A61K31/4709 , A61P1/16 , A61P7/02 , A61P9/02 , A61P9/10 , A61P11/00 , A61P11/06 , A61P17/00 , A61P17/02 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D207/12 , C07D211/46 , C07D401/12 , C07D401/14 , C07D417/14
CPC分类号: C07D401/14 , C07D207/12 , C07D211/46 , C07D401/12 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, Factor Xa and are useful in the treatment of cardiovascular disorders.
摘要翻译: 其中R2,X,Y,Cy,L和Lp(D)n具有本说明书中给出的含义的式(I)化合物是丝氨酸蛋白酶因子Xa的抑制剂,可用于治疗心血管疾病。
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公开(公告)号:US06784182B2
公开(公告)日:2004-08-31
申请号:US10030186
申请日:2002-02-04
申请人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
发明人: John Walter Liebeschuetz , Christopher William Murray , Stephen Clinton Young , Nicholas Paul Camp , Stuart Donald Jones , William Alexander Wylie , John Joseph Masters , Michael Robert Wiley , Scott Martin Sheehan , David Birenbaum Engel , Brian Morgan Watson
IPC分类号: C07D21126
CPC分类号: C07D401/14 , C07D207/12 , C07D211/46 , C07D401/12 , C07D417/14
摘要: Compounds of formula (I) in which R2, X, Y, Cy, L and Lp(D)n have the meanings given in the specification, are inhibitors of the serine protease, factor Xa and are useful in the treatment of cardiovascular disorders.
摘要翻译: 其中R2,X,Y,Cy,L和Lp(D)n具有本说明书中给出的含义的式(I)化合物是丝氨酸蛋白酶,因子Xa的抑制剂,可用于治疗心血管疾病。
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