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公开(公告)号:US07615596B2
公开(公告)日:2009-11-10
申请号:US11241016
申请日:2005-09-30
申请人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Dale A. Zellers , Penny A. Zellers, legal representative , Clay K Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn
发明人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Dale A. Zellers , Clay K Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn
IPC分类号: C08F4/42 , C08F210/00
CPC分类号: G05B13/048 , B01J8/0015 , B01J19/0006 , B01J19/0033 , B01J19/1837 , B01J19/2435 , B01J2219/00038 , B01J2219/0004 , B01J2219/00164 , B01J2219/00184 , B01J2219/00186 , B01J2219/002 , B01J2219/00218 , B01J2219/00231 , C08F2/00 , C08F10/00 , G05B13/042 , Y10S526/943
摘要: Multiple components are selected, conveyed, and measured in a polymerization system. A control system adjusts the system variables to the desired values. Portions of the components can be fed to a pre-contactor before introduction into the polymerization reactor. The catalyst component concentrations and residence times are tightly controlled in the pre-contactor to affect product properties. The pre-contactor can be a single or multiple combinations of a CSTR or plug flow pre-contactors.
摘要翻译: 在聚合系统中选择,传送和测量多个组分。 控制系统将系统变量调整到所需的值。 在引入聚合反应器之前,可以将部分成分送入预接触器。 催化剂组分浓度和停留时间在预接触器中严格控制以影响产品性能。 预接触器可以是CSTR或塞流预接触器的单个或多个组合。
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公开(公告)号:US08992840B2
公开(公告)日:2015-03-31
申请号:US12584388
申请日:2009-09-08
申请人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Clay K Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn , Penny A. Zellers
发明人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Dale A. Zellers , Clay K Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn
CPC分类号: G05B13/048 , B01J8/0015 , B01J19/0006 , B01J19/0033 , B01J19/1837 , B01J19/2435 , B01J2219/00038 , B01J2219/0004 , B01J2219/00164 , B01J2219/00184 , B01J2219/00186 , B01J2219/002 , B01J2219/00218 , B01J2219/00231 , C08F2/00 , C08F10/00 , G05B13/042 , Y10S526/943
摘要: Multiple components are selected, conveyed, and measured in a polymerization system. A control system adjusts the system variables to the desired values. Portions of the components can be fed to a pre-contactor before introduction into the polymerization reactor. The catalyst component concentrations and residence times are tightly controlled in the pre-contactor to affect product properties. The pre-contactor can be a single or multiple combinations of a CSTR or plug flow pre-contactors.
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公开(公告)号:US20090326168A1
公开(公告)日:2009-12-31
申请号:US12584388
申请日:2009-09-08
申请人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Dale A. Zellers , Penny A. Zeller , Clay K. Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn
发明人: David H. Burns , Donald W. Verser , Elizabeth A. Benham , Max P. McDaniel , John D. Hottovy , Dale A. Zellers , Penny A. Zeller , Clay K. Thurman , David A. Lockman , John O. Lawmaster , Matthew T. Haberly , Thomas H. Smith , Jerry T. Lanier , Matthew G. Thorn
CPC分类号: G05B13/048 , B01J8/0015 , B01J19/0006 , B01J19/0033 , B01J19/1837 , B01J19/2435 , B01J2219/00038 , B01J2219/0004 , B01J2219/00164 , B01J2219/00184 , B01J2219/00186 , B01J2219/002 , B01J2219/00218 , B01J2219/00231 , C08F2/00 , C08F10/00 , G05B13/042 , Y10S526/943
摘要: Multiple components are selected, conveyed, and measured in a polymerization system. A control system adjusts the system variables to the desired values. Portions of the components can be fed to a pre-contactor before introduction into the polymerization reactor. The catalyst component concentrations and residence times are tightly controlled in the pre-contactor to affect product properties. The pre-contactor can be a single or multiple combinations of a CSTR or plug flow pre-contactors.
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公开(公告)号:US20090114596A1
公开(公告)日:2009-05-07
申请号:US12183469
申请日:2008-07-31
申请人: Joshua W. KRIESEL , Timothy B. Karpishin , Donald B. Bivin , Grant Merrill , Martin S. Edelstein , Thomas H. Smith , Jeffery A. Whiteford , Robert T. Jonas , Mark Micklatcher , Serena Joshi
发明人: Joshua W. KRIESEL , Timothy B. Karpishin , Donald B. Bivin , Grant Merrill , Martin S. Edelstein , Thomas H. Smith , Jeffery A. Whiteford , Robert T. Jonas , Mark Micklatcher , Serena Joshi
CPC分类号: B82Y30/00 , C07D259/00
摘要: Nanofilms useful for filtration are prepared from oriented amphiphilic molecules and oriented macrocyclic modules. The amphiphilic species may be oriented on an interface or surface. The nanofilm may be prepared by depositing or attaching an oriented layer to a substrate. A nanofilm may also be prepared by coupling the oriented macrocyclic modules to provide a membrane.
摘要翻译: 用于过滤的纳米薄膜由取向的两亲分子和取向的大环模块制备。 两亲物种可以在界面或表面上取向。 可以通过将定向层沉积或附着到基底来制备纳米薄膜。 还可以通过将定向的大环模块偶联以提供膜来制备纳米薄膜。
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公开(公告)号:US07193041B2
公开(公告)日:2007-03-20
申请号:US09839696
申请日:2001-04-19
申请人: Brian Perry , Paul S. Nelson , Te-Tuan Yang , Thomas H. Smith
发明人: Brian Perry , Paul S. Nelson , Te-Tuan Yang , Thomas H. Smith
IPC分类号: C07D305/00
CPC分类号: B01D15/3828 , B01J20/3265 , B01J45/00 , C07K1/22 , C07K14/43595 , C07K2319/21 , C12N9/003 , G01N30/02 , B01D15/3804
摘要: Purification of poly-amino acid-tagged recombinant proteins has been improved by the use of a carboxymethylated aspartate ligand complexed with a third-block transition metal having an oxidation state of 2+ and a coordination number of 6. A method for synthesizing the metal ion-CM-Asp complex is also described. Further, the metal ion-CM-Asp complex can be used for screening protein function.
摘要翻译: 聚氨基酸标记的重组蛋白的纯化已通过使用与氧化状态为2 +和/或配位数6的第三嵌段过渡金属络合的羧甲基化天冬氨酸配体得到改善。 还描述了合成金属离子-CM-Asp络合物的方法。 此外,金属离子-CM-Asp复合物可用于筛选蛋白质功能。
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公开(公告)号:US4177264A
公开(公告)日:1979-12-04
申请号:US947874
申请日:1978-10-02
申请人: Helen Y. Wu , Thomas H. Smith , David W. Henry
发明人: Helen Y. Wu , Thomas H. Smith , David W. Henry
IPC分类号: C07H15/252 , A61K31/71 , C07H15/24
CPC分类号: C07H15/252 , Y10S514/908
摘要: N-Benzyl and N,N-dibenzyl derivatives of the anthracycline compounds adriamycin and daunomycin, said derivatives having anticancer properties and being active against leukemia P-388 in mice, for example. The N,N-dibenzyl derivatives have the unique quality of exhibiting a loss of DNA-binding properties.
摘要翻译: 所述蒽环类化合物阿霉素和道诺霉素的N-苄基和N,N-二苄基衍生物,例如,具有抗癌性的衍生物,并且对小鼠白血病P-388有活性。 N,N-二苄基衍生物具有表现出DNA结合性质丧失的独特品质。
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公开(公告)号:US08869976B1
公开(公告)日:2014-10-28
申请号:US14095501
申请日:2013-12-03
申请人: Thomas H. Smith
发明人: Thomas H. Smith
摘要: A storage case substantially in a shape of a hand-held whistle comprises two (2) halves hingedly connected to each other at a top portion. The case is provided with a storage unit located at a side surface of the case configured to hold a plurality of moistened wipes.
摘要翻译: 基本上是手持式口哨形状的储存盒包括在顶部彼此铰接连接的两(2)个半部。 壳体设置有位于壳体的侧表面处的存储单元,该存储单元构造成保持多个湿润的擦拭物。
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公开(公告)号:US08801060B1
公开(公告)日:2014-08-12
申请号:US13593414
申请日:2012-08-23
申请人: Thomas H. Smith , Richard Edgerly
发明人: Thomas H. Smith , Richard Edgerly
IPC分类号: B65G7/12
CPC分类号: B65G7/12
摘要: A carry-assist apparatus for moving heavy, cumbersome objects. The apparatus has a handle segment, an adjustable shaft segment and a hook segment, each segment of which is configured and dimensioned to permit the assembly of a spatially variable carry-assist apparatus. The hook segment is formed with a bottom having a bottom end to which optional nubs may be secured to provide positive, secure engagement to the object being lifted.
摘要翻译: 用于移动沉重,繁琐物体的携带辅助装置。 该装置具有手柄段,可调节轴段和钩段,每个段的构造和尺寸被设计成允许组装空间可变的携带辅助装置。 钩部分形成有底部,底部具有底端,可选的凸块可以固定到底部,以向被提起的物体提供正的,牢固的接合。
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公开(公告)号:US07432371B2
公开(公告)日:2008-10-07
申请号:US10359894
申请日:2003-02-07
申请人: Joshua W. Kriesel , Timothy B. Karpishin , Donald B. Bivin , Grant Merrill , Martin S. Edelstein , Thomas H. Smith , Jeffery A. Whiteford , Robert T. Jonas , Mark Micklatcher , Serena Joshi
发明人: Joshua W. Kriesel , Timothy B. Karpishin , Donald B. Bivin , Grant Merrill , Martin S. Edelstein , Thomas H. Smith , Jeffery A. Whiteford , Robert T. Jonas , Mark Micklatcher , Serena Joshi
IPC分类号: C07D291/00
CPC分类号: B82Y30/00 , C07D259/00
摘要: Nanofilms useful for filtration are prepared from oriented amphiphilic molecules and oriented macrocyclic modules. The amphiphilic species may be oriented on an interface or surface. The nanofilm may be prepared by depositing or attaching an oriented layer to a substrate. A nanofilm may also be prepared by coupling the oriented macrocyclic modules to provide a membrane.
摘要翻译: 用于过滤的纳米薄膜由取向的两亲分子和取向的大环模块制备。 两亲物种可以在界面或表面上取向。 可以通过将定向层沉积或附着到基底来制备纳米薄膜。 还可以通过将定向的大环模块偶联以提供膜来制备纳米薄膜。
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公开(公告)号:US4167374A
公开(公告)日:1979-09-11
申请号:US832821
申请日:1977-09-13
申请人: Thomas H. Smith
发明人: Thomas H. Smith
CPC分类号: F04B7/0088 , F04B53/14 , F04B7/0011 , Y10S417/90
摘要: A pump and valve arrangement includes a three-way valve at the juncture of an inlet line, an outlet line and a pumping chamber. The valve comprises a generally spherically shaped flow control member rotatable in a valve body and having an arcuate slotted passage in one side thereof adapted to communicate simultaneously with either the inlet line and pumping chamber or the outlet line and pumping chamber for alternate flow of material from the inlet line into the pumping chamber and then from the pumping chamber through the outlet line. Adjustable seat sleeves extend into the body into sealing engagement with the flow control member and a journal of the flow control member extends outwardly of the valve body and has a quick release crank attachment thereon. The pump and valve are operated in synchronism with one another by respective motors controlled from position responsive switches. The structure of the valve enables easy cleaning and servicing thereof and valve cycle times and wear on the valve are less than with prior art structures.
摘要翻译: 泵和阀装置在入口管线,出口管线和泵送室的接合处包括三通阀。 该阀包括大致球形的流动控制构件,其可在阀体中旋转并且在其一侧具有弧形开槽通道,其适于与入口管线和泵送室或出口管线和泵送室同时连通,用于从 入口线进入泵送室,然后从泵送室通过出口管路。 可调节的座套筒延伸到主体中与流量控制构件密封接合,并且流量控制构件的轴颈延伸到阀体的外部并且在其上具有快速释放曲柄附件。 泵和阀通过由位置响应开关控制的相应电动机彼此同步地操作。 阀的结构使得易于清洁和维修,并且阀循环时间和阀上的磨损小于现有技术结构。
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