公开(公告)号：US08452375B2

公开(公告)日：2013-05-28

申请号：US10745104

申请日：2003-12-23

申请人： David Krag ,  Eric Meier ,  Steve Dimmer ,  Duane Durbin ,  Trevor Moody ,  Fred Silverstein ,  Rosemary Harry ,  Richard Frecksa ,  Amy Kinsella ,  Jon Gilbert

发明人： David Krag ,  Eric Meier ,  Steve Dimmer ,  Duane Durbin ,  Trevor Moody ,  Fred Silverstein ,  Rosemary Harry ,  Richard Frecksa ,  Amy Kinsella ,  Jon Gilbert

IPC分类号： A61B5/055 ,  A61B19/00

CPC分类号： A61B17/32053 ,  A61B17/3201 ,  A61B17/3211 ,  A61B17/3403 ,  A61B34/20 ,  A61B34/25 ,  A61B34/74 ,  A61B90/36 ,  A61B90/39 ,  A61B90/90 ,  A61B90/92 ,  A61B90/98 ,  A61B2017/00349 ,  A61B2017/320064 ,  A61B2017/3413 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2034/2072 ,  A61B2090/3908 ,  A61B2090/392 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3933 ,  A61B2090/3937 ,  A61B2090/3941 ,  A61B2090/395 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/3975 ,  A61B2090/3983 ,  A61B2090/3995

摘要： Systems and methods for locating and defining a target location within a human body. The system can include at least one marker, a probe, and a detector for use in locating the markers by providing information to a surgeon that is representative of changes in proximity between the probe and the marker. The marker can have various detection characteristics, e.g., gamma radiation, that are detectable by an associated probe and detector. The tissue volume is removed by manipulating a cutting tool based on the proximity information provided by the detector, which can be used by the surgeon to define the boundary of the tissue volume. The systems and methods of the invention are particularly useful in locating and then removing a tissue volume or other target location from amorphous, pliable tissue (e.g., breast tissue) or other body parts.

公开(公告)号：US20060078086A1

公开(公告)日：2006-04-13

申请号：US11189431

申请日：2005-07-25

申请人： James Riley ,  Eric Meier ,  J. Wright ,  Steven Dimmer ,  Timothy Mate

发明人： James Riley ,  Eric Meier ,  J. Wright ,  Steven Dimmer ,  Timothy Mate

IPC分类号： A61N5/10

CPC分类号： A61N5/1038 ,  A61N5/103 ,  A61N5/1048

摘要： A facility for facilitating custom radiation treatment planning is described. During a distinguished radiation treatment session for a patient, the facility collects data indicating positioning of a predefined treatment site of the patient relative to a target treatment location throughout the distinguished radiation treatment session. The facility associates the collected positioning data with data describing one or more other aspects of the distinguished radiation treatment session. The facility provides the associated data to a treatment planning facility to determine a treatment plan for future radiation treatment sessions for the patient.

公开(公告)号：US08340742B2

公开(公告)日：2012-12-25

申请号：US11190196

申请日：2005-07-25

申请人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

发明人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

摘要翻译： 综合放射治疗过程包括通过使用定位模式周期性地定位位于患者内的标记来获取与患者内的目标参数有关的第一目标目标数据。 该方法继续通过周期性地定位标记来获得与目标参数相关的第二目标目标数据。 第一目标数据可以在离开包含用于产生用于治疗患者的电离辐射束的辐射递送装置的第二区域的第一区域中获取。 第一和第二区域的定位方式可以相同。 在其他实施例中，可以使用使用第一能量类型来识别标记的第一定位模态来获取第一目标目标数据，并且可以使用第二定位模式来获得第二目标数据，第二定位模式使用第二能量类型来识别 不同于第一种能量类型的标记。

公开(公告)号：US08244330B2

公开(公告)日：2012-08-14

申请号：US11190195

申请日：2005-07-25

申请人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

发明人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

公开(公告)号：US20060074302A1

公开(公告)日：2006-04-06

申请号：US11190196

申请日：2005-07-25

申请人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

发明人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

摘要翻译： 综合放射治疗过程包括通过使用定位模式周期性地定位位于患者内的标记来获取与患者内的目标参数有关的第一目标目标数据。 该方法继续通过周期性地定位标记来获得与目标参数相关的第二目标目标数据。 第一目标数据可以在离开包含用于产生用于治疗患者的电离辐射束的辐射递送装置的第二区域的第一区域中获取。 第一和第二区域的定位方式可以相同。 在其他实施例中，可以使用使用第一能量类型来识别标记的第一定位模态来获取第一目标目标数据，并且可以使用第二定位模式来获得第二目标数据，第二定位模式使用第二能量类型来识别 不同于第一种能量类型的标记。

公开(公告)号：US09616248B2

公开(公告)日：2017-04-11

申请号：US13559518

申请日：2012-07-26

申请人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

发明人： Eric Meier ,  Timothy P. Mate ,  J. Nelson Wright ,  Steven C. Dimmer ,  Lynn M. Purdy

IPC分类号： A61B5/05 ,  A61N5/10

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy.

公开(公告)号：US08437449B2

公开(公告)日：2013-05-07

申请号：US11189431

申请日：2005-07-25

申请人： James K. Riley ,  Eric Meier ,  J. Nelson Wright ,  Steven C. Dimmer ,  Timothy P. Mate

发明人： James K. Riley ,  Eric Meier ,  J. Nelson Wright ,  Steven C. Dimmer ,  Timothy P. Mate

IPC分类号： A61N5/10 ,  A61B5/00

CPC分类号： A61N5/1038 ,  A61N5/103 ,  A61N5/1048

摘要： A facility for facilitating custom radiation treatment planning is described. During a distinguished radiation treatment session for a patient, the facility collects data indicating positioning of a predefined treatment site of the patient relative to a target treatment location throughout the distinguished radiation treatment session. The facility associates the collected positioning data with data describing one or more other aspects of the distinguished radiation treatment session. The facility provides the associated data to a treatment planning facility to determine a treatment plan for future radiation treatment sessions for the patient.

摘要翻译： 描述了一种便于定制辐射治疗计划的设施。 在针对患者的不同的辐射治疗期间，设施收集指示患者相对于目标治疗位置在整个识别的辐射治疗期间的定位的数据。 该设施将收集的定位数据与描述不同的辐射治疗会话的一个或多个其他方面的数据相关联。 该设施将相关数据提供给治疗计划设施，以确定患者将来的放射治疗期间的治疗计划。

公开(公告)号：US10195464B2

公开(公告)日：2019-02-05

申请号：US11165843

申请日：2005-06-24

申请人： Edward J. Vertatschitsch ,  Steven C. Dimmer ,  Timothy P. Mate ,  Eric Meier ,  Keith Seiler ,  J. Nelson Wright

发明人： Edward J. Vertatschitsch ,  Steven C. Dimmer ,  Timothy P. Mate ,  Eric Meier ,  Keith Seiler ,  J. Nelson Wright

IPC分类号： A61B5/05 ,  A61N5/10 ,  A61B34/30 ,  A61B34/00 ,  A61B90/00

摘要： Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.

公开(公告)号：US20090216113A1

公开(公告)日：2009-08-27

申请号：US12159554

申请日：2006-11-17

申请人： Eric Meier ,  Steven C. Dimmer ,  J. Nelson Wright ,  Rich Edelson

发明人： Eric Meier ,  Steven C. Dimmer ,  J. Nelson Wright ,  Rich Edelson

IPC分类号： A61B5/05

CPC分类号： A61B17/32 ,  A61B5/0002 ,  A61B5/062 ,  A61B5/4504 ,  A61B5/686 ,  A61B17/15 ,  A61B17/155 ,  A61B17/157 ,  A61B17/17 ,  A61B17/1757 ,  A61B90/39 ,  A61B2017/320052 ,  A61B2090/3958 ,  A61B2090/3966 ,  A61B2090/3975 ,  A61B2090/3991 ,  A61F2/32 ,  A61F2/38 ,  A61F2/441 ,  A61F2002/3067 ,  A61F2250/0002 ,  G06F19/00

摘要： Electromagnetic transponders as markers are used to localize and guide orthopedic procedures including: knee replacement, hip replacement, shoulder replacement, damaged bone reconstruction, and spine surgery, and more particularly, to guide orthopedic surgical navigation and alignment techniques and instruments. For example, the marker could further be used in any number of guides or templates that attach to the bony anatomy, such as a surgical guide, cutting guide, cutting jig, resection block and/or resurfacing guide. Further, the marker could be incorporated into an existing intramedullary guide rod for a femur and an extramedullary guide rod for a tibia in a knee replacement surgery; or into an external surgical guide system, or the marker could eliminate the need for an external template altogether. According to yet another anticipated use of the tracking system, the marker could be used in conjunction with or replace an optical alignment system.

摘要翻译： 电磁转发器作为标记用于定位和引导矫形手术，包括：膝关节置换，髋关节置换，肩关节置换，骨重建受损和脊柱手术，更具体地，指导骨科手术导航和对准技术和手段。 例如，标记可以进一步用于附着于骨骼解剖结构的任何数量的引导件或模板中，例如手术引导件，切割引导件，切割夹具，切除块和/或表面置换引导件。 此外，标记可以结合到膝关节置换手术中用于股骨的现有髓内导杆和用于胫骨的髓外导杆; 或进入外部手术引导系统，或者标记可以完全消除对外部模板的需要。 根据跟踪系统的另一预期使用，标记可以与光学对准系统结合使用或替代光学对准系统。

公开(公告)号：US20060074301A1

公开(公告)日：2006-04-06

申请号：US11190193

申请日：2005-07-25

申请人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

发明人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.