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    SYSTEM FOR INCUBATING THE CONTENTS OF A REACTION RECEPTACLE
    3.
    发明申请
    SYSTEM FOR INCUBATING THE CONTENTS OF A REACTION RECEPTACLE 有权
    破坏反应装置内容的系统

    公开(公告)号：US20120070884A1

    公开(公告)日：2012-03-22

    申请号：US13232459

    申请日：2011-09-14

    申请人： Kelly G. AMMANN ,  Robert E. Schneider ,  Robert J. Smith

    发明人： Kelly G. AMMANN ,  Robert E. Schneider ,  Robert J. Smith

    IPC分类号： C12M1/40

    CPC分类号： B01L7/5255 ,  B01L7/52 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  G01N35/0098 ,  G01N35/0099 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/115831 ,  Y10T436/119163 ,  Y10T436/25 ,  Y10T436/2575

    摘要： An automated analyzer for performing multiple diagnostic assays includes multiple modules in which aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a sample, pre-heating the sample, incubating the sample, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. A receptacle transporting system moves reaction receptacles from one station to the next. A method for performing an assay includes an automated process for isolating and amplifying a target analyte. The process is performed by moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for pre-heating and incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the analyte after the separation step and before incubation.

    摘要翻译： 用于执行多个诊断测定的自动化分析仪包括多个模块，其中对反应容器中包含的流体样品进行测定的方面。 分析仪包括用于自动准备样品，预加热样品，孵育样品，进行分析物分离程序和确定目标分析物的存在的站。 插座运输系统将反应容器从一个站移动到另一个站。 用于进行测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程是通过在站之间移动包含固体支持材料和流体样品的多个反应容器中的每一个进行的，以预热和温育反应容器的内容物，并将与固体支持物结合的目标分析物与流体分离 样品。 在分离步骤之后和孵育前将扩增试剂加入到分析物中。

    Temperature-controlled incubator having an arcuate closure panel
    4.
    发明授权
    Temperature-controlled incubator having an arcuate closure panel 有权
    温度控制的孵化器具有弓形封闭面板

    公开(公告)号：US08137620B2

    公开(公告)日：2012-03-20

    申请号：US11869300

    申请日：2007-10-09

    申请人： Kelly G. Ammann ,  Robert E. Schneider ,  Robert J. Smith

    发明人： Kelly G. Ammann ,  Robert E. Schneider ,  Robert J. Smith

    IPC分类号： C12M1/36

    CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品的台站，在规定温度下培养样品规定的时间，进行分析物分离程序，并确定目标分析物的存在。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

    Method for Agitating the Contents of A Reaction Receptacle Within A Temperature-Controlled Environment
    8.
    发明申请
    Method for Agitating the Contents of A Reaction Receptacle Within A Temperature-Controlled Environment 有权
    在温度控制环境中搅拌反应容器内容物的方法

    公开(公告)号：US20090067280A1

    公开(公告)日：2009-03-12

    申请号：US11875306

    申请日：2007-10-19

    申请人： Kelly G. Ammann ,  Robert E. Schneider ,  Robert J. Smith

    发明人： Kelly G. Ammann ,  Robert E. Schneider ,  Robert J. Smith

    IPC分类号： B01F15/06

    CPC分类号： C12Q1/6834 ,  B01F9/0001 ,  B01F9/0014 ,  B01F9/0021 ,  B01F2009/0074 ,  B01L7/52 ,  B01L7/5255 ,  B01L9/06 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2300/1827 ,  B03C1/282 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/26 ,  C12Q1/6813 ,  C12Q1/6832 ,  C12Q2537/10 ,  G01N35/0098 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1065 ,  G01N2035/00356 ,  G01N2035/00524 ,  G01N2035/0437 ,  G01N2035/0455 ,  G01N2035/103 ,  Y10T29/53657 ,  Y10T29/53683 ,  Y10T29/53843 ,  Y10T156/1105 ,  Y10T156/1906 ,  Y10T436/11 ,  Y10T436/111666 ,  Y10T436/113332 ,  Y10T436/114998 ,  Y10T436/119163 ,  Y10T436/2575

    摘要： An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.

    摘要翻译： 用于执行多个诊断测定的自动分析仪同时包括多个站或模块，其中对反应容器中包含的流体样品进行分析方面的分析。 分析仪包括用于自动准备标本样品，在规定温度下规定时间孵育样品，进行分析物分离程序，以及确定目标分析物的存在的站。 自动插座输送系统将反应容器从一个站移动到另一个站。 分析仪还包括用于以机器可接近的方式携带多个样本管和一次性移液管尖端的装置，用于搅拌包含固体支持材料的悬浮液并用于提供用于机器通入的容器的靶捕获试剂的容器的装置，以及 用于在温度受控的环境中容纳试剂容器的装置，并且提供用于机器通入的容器。 执行自动诊断测定的方法包括用于分离和扩增靶分析物的自动化方法。 该过程通过在站之间自动移动包含固体支持材料和流体样品的多个反应容器中的每一个来进行，用于孵育反应容器的内容物并将与固体支持物结合的目标分析物与流体样品分离。 在分析物分离步骤之后和最终孵育步骤之前，将分离的分析物加入扩增试剂。

    FLAVORING COMPOSITION AND PROCESS FOR BREWING MALT BEVERAGES
    10.
    发明申请
    FLAVORING COMPOSITION AND PROCESS FOR BREWING MALT BEVERAGES 审中-公开
    烧烤组合物和焙烧麦芽饮料的方法

    公开(公告)号：US20080160155A1

    公开(公告)日：2008-07-03

    申请号：US12037852

    申请日：2008-02-26

    申请人： Adam M. Gimbel ,  Trevor R. Roberts ,  Robert J. Smith ,  Richard J.H. Wilson

    发明人： Adam M. Gimbel ,  Trevor R. Roberts ,  Robert J. Smith ,  Richard J.H. Wilson

    IPC分类号： C12C3/00

    CPC分类号： C12C5/026 ,  C12C3/00 ,  C12C3/08 ,  C12C3/10 ,  C12C3/12 ,  C12C5/00 ,  C12C5/02 ,  C12C7/20 ,  C12C11/003

    摘要： An improved flavoring composition and process for brewing malt beverages is disclosed. In one embodiment of the invention, the flavoring composition is formed from a high solids percent, room temperature stable, partially aqueous composition of a potassium salt of iso-α-acids. Such composition may be added to the wort kettle or else used as a post-fermentation additive, preferably after dilution with demineralized water. In another embodiment, the flavoring composition comprises a mixture containing reduced (rho-) iso-α-acids in alkali metal salts form, β-acids and hop oil. This latter composition is useful as a substitute for normal kettle extract, hops or hop pellets, allowing easy preparation of beer that resists formation of unpleasant, “skunky” flavors but has otherwise similar flavor and physical properties.

    摘要翻译： 公开了一种用于酿造麦芽饮料的改进的调味组合物和方法。 在本发明的一个实施方案中，调味组合物由异α酸的钾盐的高固体％，室温稳定的部分水性组合物形成。 这种组合物可以加入到麦芽汁壶中，或者用作发酵后添加剂，优选用软化水稀释后。 在另一个实施方案中，调味组合物包含含有碱金属盐形式的β-还原（α-（Rho））异α-酸的混合物，β-酸和啤酒花油。 后一种组合物可用作正常的壶提取物，啤酒花或啤酒花球团的替代物，可以容易地制备能抵抗形成令人不愉快的“天然”味道的啤酒，但是具有相似的风味和物理性质。