Acyl-phenoxy-propanesulfoacids and salts, and artificial sweetening
compositions containing the same
    3.
    发明授权
    Acyl-phenoxy-propanesulfoacids and salts, and artificial sweetening compositions containing the same 失效
    酰基 - 苯氧基 - 丙磺酸和盐,以及含有它们的人造甜味组合物

    公开(公告)号:US4092346A

    公开(公告)日:1978-05-30

    申请号:US746350

    申请日:1976-12-01

    CPC分类号: C07C309/11 A23L27/30

    摘要: Compounds of the formula (1), or their salts, ##STR1## are prepared as follows: (A) A COMPOUND OF THE FORMULA (II) ##STR2## is reduced; or (B) A COMPOUND OF THE FORMULA (III) ##STR3## is reacted, e.g. after protecting the phenolic hydroxy group attached to position 3 of the ring, with a compound of the formula (IV), ##STR4## or (C) GROUP R.sup.1 of a compound of the formula (V) ##STR5## is removed in an acidic medium, AND, IF DESIRED, THE COMPOUND OF THE FORMULA (I) is converted into salt, or a salt of a compound of the formula (I) is converted into the free acid or another salt thereof.The compounds of the formula (I) and their salts are valuable artificial sweetening agents.In the above formulae"alkyl" is a C.sub.1-4 alkyl group,R is hydrogen or a protecting group capable of splitting off upon hydrogenolysis, preferably benzyl or benzyloxycarbonyl,M+ is a proton or another cation,X is a group of the general formula O.sup.- M.sup.+,Y is halogen, orX and Y together represent an oxygen atom, andR.sup.1 is a protecting group capable of splitting off in acidic media, such as 2-tetrahydropyranyl or 1-ethoxyethyl.

    摘要翻译: 式(1)化合物或其盐,如下制备: