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    Bicarbonate-based solution in two parts for peritoneal dialysis or substitution in continuous renal replacement therapy
    4.
    发明授权
    Bicarbonate-based solution in two parts for peritoneal dialysis or substitution in continuous renal replacement therapy 失效
    碳酸氢盐溶液在两部分用于腹膜透析或连续肾替代治疗中的替代

    公开(公告)号：US06309673B1

    公开(公告)日：2001-10-30

    申请号：US09393743

    申请日：1999-09-10

    申请人： Annick Duponchelle ,  Dirk Faict ,  Patrick Balteau ,  Jean-Pierre Hartman ,  Leo Martis ,  Francesco Peluso

    发明人： Annick Duponchelle ,  Dirk Faict ,  Patrick Balteau ,  Jean-Pierre Hartman ,  Leo Martis ,  Francesco Peluso

    IPC分类号： A61K3300

    CPC分类号： A61M1/287 ,  A61K33/14 ,  A61M1/1654 ,  A61K33/10 ,  A61K2300/00

    摘要： The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts—an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.

    摘要翻译： 本发明提供用于稳定用于腹膜透析或血液滤过的基于碳酸氢根的溶液的装置和方法。 将本发明的基于碳酸氢盐的溶液配制并储存在至少两部分中 - 碱性碳酸氢盐浓缩物和酸性浓缩物。 将碱式碳酸氢盐浓缩物调节至约8.6至10.0的pH。 将酸性浓缩物调节至具有约1.0至3.0的稳定的酸性pH。 在混合时，虽然存在混合碳酸氢盐溶液的pH的一些变化，本发明人已经发现，通过适当选择浓缩物的参数，混合溶液的pH总是在可接受的生理范围内。

    Multiple chamber container
    7.
    发明授权
    Multiple chamber container 失效
    多室容器

    公开(公告)号：US5431496A

    公开(公告)日：1995-07-11

    申请号：US295363

    申请日：1994-08-24

    申请人： Patrick Balteau ,  Dirk Faict ,  Francesco Peluso

    发明人： Patrick Balteau ,  Dirk Faict ,  Francesco Peluso

    IPC分类号： B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22

    CPC分类号： A61J1/2093 ,  A61J1/10 ,  A61J1/2027 ,  A61M1/28

    摘要： A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

    摘要翻译： 一种用于混合和施用多种产品的多室容器。 容器具有至少两个由密封线隔开的室。 一个易碎连接器位于两个室之间，用于根据需要混合容纳在室内的产品。 每个室具有至少一个用于将产品填充到室中的端口。 端口位于容器的相同的外侧，使得可以在不折叠袋子的情况下填充室并且使用现有的填充设备。