System, method and computer accessible medium for providing real-time diffusional kurtosis imaging and for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging
    3.
    发明授权
    System, method and computer accessible medium for providing real-time diffusional kurtosis imaging and for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging 有权
    系统,方法和计算机可访问介质,用于提供实时扩散峰度成像,并有助于估计扩张峰度成像中的张量和张量推导测量

    公开(公告)号:US08811706B2

    公开(公告)日:2014-08-19

    申请号:US13022488

    申请日:2011-02-07

    IPC分类号: G06T7/00 A61B5/055

    CPC分类号: G01R33/56341

    摘要: Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and determining a measure of a diffusional kurtosis as a function of the received data using a closed form solution procedure. In accordance with certain exemplary embodiments of the present disclosure, provided herein are computer-accessible medium, systems and methods for, e.g., imaging in an MRI system, and, more particularly for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging (DKI). For example, DKI can facilitate a characterization of non-Gaussian diffusion of water molecules in biological tissues. The diffusion and kurtosis tensors parameterizing the DKI model can typically be estimated via unconstrained least squares (LS) methods. In the presence of noise, motion, and imaging artifacts, these methods can be prone to producing physically and/or biologically implausible tensor estimates. The exemplary embodiments of the present disclosure can address at least this deficiency by formulating an exemplary estimation problem, e.g., as linearly constrained linear LS, where the constraints can ensure acceptable tensor estimates.

    摘要翻译: 可以提供示例性方法,系统和计算机可访问介质,用于通过接收与至少一个扩散加权图像相关的数据来确定扩散峰度的度量,并且使用闭合的方法确定作为接收数据的函数的扩散峰度的度量 形式解决程序。 根据本公开的某些示例性实施例,本文提供了用于例如在MRI系统中成像的计算机可访问介质,系统和方法,并且更具体地,用于促进扩散峭度成像中的张量和张量导出测量的估计 (DKI)。 例如,DKI可以促进水分子在生物组织中的非高斯扩散的表征。 参数化DKI模型的扩散和峰度张量通常可以通过非约束最小二乘法(LS)方法估计。 在存在噪声,运动和成像伪像的情况下,这些方法可能容易产生物理和/或生物学不可信的张量估计。 本公开的示例性实施例可以通过制定示例性估计问题(例如线性约束线性LS)来解决至少该缺陷,其中约束可以确保可接受的张量估计。

    System, Method and Computer Accessible Medium for Providing Real-Time Diffusional Kurtosis Imaging and for Facilitating Estimation of Tensors and Tensor- Derived Measures in Diffusional Kurtosis Imaging
    4.
    发明申请
    System, Method and Computer Accessible Medium for Providing Real-Time Diffusional Kurtosis Imaging and for Facilitating Estimation of Tensors and Tensor- Derived Measures in Diffusional Kurtosis Imaging 有权
    系统,方法和计算机可访问介质,用于提供实时扩散性血液饱和成像和促进传感器估计和弥漫性高血压成像中的传感器测量

    公开(公告)号:US20120002851A1

    公开(公告)日:2012-01-05

    申请号:US13022488

    申请日:2011-02-07

    IPC分类号: G06K9/00

    CPC分类号: G01R33/56341

    摘要: Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and determining a measure of a diffusional kurtosis as a function of the received data using a closed form solution procedure. In accordance with certain exemplary embodiments of the present disclosure, provided herein are computer-accessible medium, systems and methods for, e.g., imaging in an MRI system, and, more particularly for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging (DKI). For example, DKI can facilitate a characterization of non-Gaussian diffusion of water molecules in biological tissues. The diffusion and kurtosis tensors parameterizing the DKI model can typically be estimated via unconstrained least squares (LS) methods. In the presence of noise, motion, and imaging artifacts, these methods can be prone to producing physically and/or biologically implausible tensor estimates. The exemplary embodiments of the present disclosure can address at least this deficiency by formulating an exemplary estimation problem, e.g., as linearly constrained linear LS, where the constraints can ensure acceptable tensor estimates.

    摘要翻译: 可以提供示例性方法,系统和计算机可访问介质,用于通过接收与至少一个扩散加权图像相关的数据来确定扩散峰度的度量,并且使用闭合的方法确定作为接收数据的函数的扩散峰度的度量 形式解决程序。 根据本公开的某些示例性实施例,本文提供了用于例如在MRI系统中成像的计算机可访问介质,系统和方法,并且更具体地,用于促进扩散峭度成像中的张量和张量导出测量的估计 (DKI)。 例如,DKI可以促进水分子在生物组织中的非高斯扩散的表征。 参数化DKI模型的扩散和峰度张量通常可以通过非约束最小二乘法(LS)方法估计。 在存在噪声,运动和成像伪像的情况下,这些方法可能容易产生物理和/或生物学不可信的张量估计。 本公开的示例性实施例可以通过制定示例性估计问题(例如线性约束线性LS)来解决至少该缺陷,其中约束可以确保可接受的张量估计。

    METHOD, SYSTEM AND SOFTWARE ARRANGEMENT FOR MEASURING MAGNETIC FIELD CORRELATION
    5.
    发明申请
    METHOD, SYSTEM AND SOFTWARE ARRANGEMENT FOR MEASURING MAGNETIC FIELD CORRELATION 有权
    用于测量磁场相关性的方法,系统和软件布置

    公开(公告)号:US20100207626A1

    公开(公告)日:2010-08-19

    申请号:US12710035

    申请日:2010-02-22

    IPC分类号: G01R33/44

    摘要: Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

    摘要翻译: 用于测量磁场相关函数(“MFC”)的方法,系统,软件布置和存储介质,更具体地说,涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列(“ADSE”)和回波平面成像不对称双自旋回波序列(“EPI-ADSE”)将多个回波应用于样本,并获取可以确定MFC的数据。

    Method, system and software arrangement for measuring magnetic field correlation
    6.
    发明授权
    Method, system and software arrangement for measuring magnetic field correlation 有权
    用于测量磁场相关性的方法,系统和软件布置

    公开(公告)号:US07852078B2

    公开(公告)日:2010-12-14

    申请号:US12710035

    申请日:2010-02-22

    IPC分类号: G01V3/00

    摘要: Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

    摘要翻译: 用于测量磁场相关函数(“MFC”)的方法,系统,软件布置和存储介质,更具体地说,涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列(“ADSE”)和回波平面成像不对称双自旋回波序列(“EPI-ADSE”)将多个回波应用于样本,并获取可以确定MFC的数据。

    Method, system and software arrangement, for measuring magnetic field correlation
    7.
    发明授权
    Method, system and software arrangement, for measuring magnetic field correlation 有权
    方法,系统和软件安排,用于测量磁场相关性

    公开(公告)号:US07667459B2

    公开(公告)日:2010-02-23

    申请号:US10564697

    申请日:2004-07-08

    IPC分类号: G01V3/00

    摘要: Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

    摘要翻译: 用于测量磁场相关函数(“MFC”)的方法,系统,软件布置和存储介质,更具体地说,涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列(“ADSE”)和回波平面成像不对称双自旋回波序列(“EPI-ADSE”)将多个回波应用于样本,并获取可以确定MFC的数据。

    Method, system and software arrangement, for measuring magnetic field correlation
    9.
    发明申请
    Method, system and software arrangement, for measuring magnetic field correlation 有权
    方法,系统和软件安排,用于测量磁场相关性

    公开(公告)号:US20060160242A1

    公开(公告)日:2006-07-20

    申请号:US10564697

    申请日:2004-07-08

    IPC分类号: G01N24/00

    摘要: Methods, systems, software arrangements and storage medium for measuring the magnetic field correlation function (“MFC”), and more particularly, to methods for measuring the magnetic field correlation function utilizing asymmetric spin echoes. Asymmetric Dual Spin Echo Sequences (“ADSE”) and Echo Planar Imaging Asymmetric Dual Spin Echo Sequences (“EPI-ADSE”) may be employed to apply multiple echoes to a sample and acquire data from which the MFC may be determined.

    摘要翻译: 用于测量磁场相关函数(“MFC”)的方法,系统,软件布置和存储介质,更具体地说,涉及利用非对称自旋回波测量磁场相关函数的方法。 可以采用非对称双自旋回波序列(“ADSE”)和回波平面成像不对称双自旋回波序列(“EPI-ADSE”)将多个回波应用于样本,并获取可以确定MFC的数据。

    Open unipolar magnetic structure
    10.
    发明授权
    Open unipolar magnetic structure 失效
    开放单极磁结构

    公开(公告)号:US06265959B1

    公开(公告)日:2001-07-24

    申请号:US09069389

    申请日:1998-04-29

    IPC分类号: H01F500

    摘要: A magnetic structure generating a uniform magnetic field within a region of interest using permanently magnetized prism-shaped blocks of magnetic material positioned around a cavity and which constitute the predominant generator of the uniform magnetic field in the desired region of interest. The magnetic structure has a plane surface comprising a high permeability ferromagnetic member interfacing with a first side of the cavity and forming a single pole piece of the magnetic structure. The magnetic structure produces within the cavity adjacent the single pole piece the uniform magnetic field and collects the magnetic flux flowing through the single pole piece and through the cavity, with the region of interest being located adjacent the single pole piece. A second side of the cavity generally opposite to the first side is open to a surrounding medium and forms an interface with the surrounding medium but not with a magnetic member. The magnetic structure is designed assuming a hypothetical high permeability membrane parallel to the single pole piece and located where the open second side of the cavity will be made, the high permeability membrane forming an equipotential surface at the interface with the surrounding medium. This minimizes the fringe field generated in the surrounding medium when the second side of the cavity is opened.

    摘要翻译: 一种磁性结构,其在感兴趣的区域内使用位于空腔周围的永久磁化的棱柱形磁性材料块产生均匀磁场,并且构成所需感兴趣区域中均匀磁场的主要发生器。 磁性结构具有包括与空腔的第一侧接合的高磁导率铁磁构件的平面,并形成磁结构的单极片。 磁性结构在与单极片相邻的腔内产生均匀的磁场,并收集流过单极片并通过腔的磁通量,感兴趣区域位于单极片附近。 大致与第一侧相对的空腔的第二侧对周围的介质是开放的,并与周围的介质形成界面而不与磁性构件形成界面。 磁性结构被设计为假设与单极片平行的假想高渗透膜,并且位于将形成空腔的开口第二侧的位置,高渗透膜在与周围介质的界面处形成等电位面。 当空腔的第二侧被打开时,这最小化周围介质中产生的边缘场。