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公开(公告)号：US07601173B2
公开(公告)日：2009-10-13
申请号：US11745343
申请日：2007-05-07
IPC分类号： A61F2/44
CPC分类号： A61F2/28 , A61F2/4455 , A61F2002/30014 , A61F2002/30032 , A61F2002/30057 , A61F2002/30387 , A61F2002/30448 , A61F2002/30492 , A61F2002/30604 , A61F2002/30843 , A61F2002/30904 , A61F2220/0025 , A61F2220/005 , A61F2250/0018 , A61F2250/003
摘要： An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part, composed of cancellous bone, is ductile and promotes the growth of new bone between the vertebrae being treated and the implant, thus fusing the vertebrae to the implant and to each other. The implant is sized and shaped to conform to the space between the vertebrae. Teeth formed on the superior and inferior surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由两部分组成。 第一部分由皮质骨组成，为植入物提供机械强度，允许正在治疗的椎骨之间的适当距离保持不变。 由松质骨组成的第二部分是延性的并且促进正在被治疗的椎骨和植入物之间的新骨的生长，从而将椎骨融合到植入物和彼此之间。 植入物的尺寸和形状适合于椎骨之间的空间。 在植入物的上表面和下表面上形成的齿防止植入物的短期滑动。
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公开(公告)号：US07226482B2
公开(公告)日：2007-06-05
申请号：US10931788
申请日：2004-09-01
IPC分类号： A61F2/44
CPC分类号： A61F2/28 , A61F2/4455 , A61F2002/30014 , A61F2002/30032 , A61F2002/30057 , A61F2002/30387 , A61F2002/30448 , A61F2002/30492 , A61F2002/30604 , A61F2002/30843 , A61F2002/30904 , A61F2220/0025 , A61F2220/005 , A61F2250/0018 , A61F2250/003
摘要： An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part, composed of cancellous bone, is ductile and promotes the growth of new bone between the vertebrae being treated and the implant, thus fusing the vertebrae to the implant and to each other. The implant is sized and shaped to conform to the space between the vertebrae. Teeth formed on the superior and inferior surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由两部分组成。 第一部分由皮质骨组成，为植入物提供机械强度，允许正在治疗的椎骨之间的适当距离保持不变。 由松质骨组成的第二部分是延性的并且促进正在被治疗的椎骨和植入物之间的新骨的生长，从而将椎骨融合到植入物和彼此之间。 植入物的尺寸和形状适合于椎骨之间的空间。 在植入物的上表面和下表面上形成的齿防止植入物的短期滑动。
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公开(公告)号：US07491237B2
公开(公告)日：2009-02-17
申请号：US11093111
申请日：2005-03-28
申请人： Brandon L Randall , Roger D Goodwin , Dominique Messerli , Jacqueline Myer , Robert J Delurio , Michael L Boyer, II , Christopher M Angelucci
发明人： Brandon L Randall , Roger D Goodwin , Dominique Messerli , Jacqueline Myer , Robert J Delurio , Michael L Boyer, II , Christopher M Angelucci
IPC分类号： A61F2/44
CPC分类号： A61F2/44 , A61F2/28 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30057 , A61F2002/30266 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30507 , A61F2002/30571 , A61F2002/30604 , A61F2002/30617 , A61F2002/30782 , A61F2002/30795 , A61F2002/3082 , A61F2002/30843 , A61F2002/30904 , A61F2002/4622 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2230/0082 , A61F2250/0097 , A61F2310/00359
摘要： An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由一个或多个两片形成。 这些片由骨制成，并且连接在一起以形成具有足够强度和稳定性的植入物，以在脊柱融合程序中保持第一和第二椎骨之间的期望距离。 植入物片可以由皮质骨形成并且通过燕尾接头连接，并且可以提供至少一个皮质骨针将锁定在一起并增加植入物的强度。 牙齿形成在植入物的椎骨接合表面上，防止植入物的短期滑动。
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公开(公告)号：US20050240267A1
公开(公告)日：2005-10-27
申请号：US11093111
申请日：2005-03-28
申请人： Brandon Randall , Roger Goodwin , Dominique Messerli , Jacqueline Myer , Robert Delurio , Michael Boyer , Christopher Angelucci
发明人： Brandon Randall , Roger Goodwin , Dominique Messerli , Jacqueline Myer , Robert Delurio , Michael Boyer , Christopher Angelucci
CPC分类号： A61F2/44 , A61F2/28 , A61F2/3094 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30057 , A61F2002/30266 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30507 , A61F2002/30571 , A61F2002/30604 , A61F2002/30617 , A61F2002/30782 , A61F2002/30795 , A61F2002/3082 , A61F2002/30843 , A61F2002/30904 , A61F2002/4622 , A61F2002/4628 , A61F2002/4629 , A61F2220/0025 , A61F2230/0082 , A61F2250/0097 , A61F2310/00359
摘要： An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由一个或多个两片形成。 这些片由骨制成，并且连接在一起以形成具有足够强度和稳定性的植入物，以在脊柱融合程序中保持第一和第二椎骨之间的期望距离。 植入物片可以由皮质骨形成并且通过燕尾接头连接，并且可以提供至少一个皮质骨针将锁定在一起并增加植入物的强度。 牙齿形成在植入物的椎骨接合表面上，防止植入物的短期滑动。
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公开(公告)号：US20070208424A1
公开(公告)日：2007-09-06
申请号：US11745343
申请日：2007-05-07
IPC分类号： A61F2/44
CPC分类号： A61F2/28 , A61F2/4455 , A61F2002/30014 , A61F2002/30032 , A61F2002/30057 , A61F2002/30387 , A61F2002/30448 , A61F2002/30492 , A61F2002/30604 , A61F2002/30843 , A61F2002/30904 , A61F2220/0025 , A61F2220/005 , A61F2250/0018 , A61F2250/003
摘要： An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part, composed of cancellous bone, is ductile and promotes the growth of new bone between the vertebrae being treated and the implant, thus fusing the vertebrae to the implant and to each other. The implant is sized and shaped to conform to the space between the vertebrae. Teeth formed on the superior and inferior surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由两部分组成。 第一部分由皮质骨组成，为植入物提供机械强度，允许正在治疗的椎骨之间的适当距离保持不变。 由松质骨组成的第二部分是延性的并且促进正在被治疗的椎骨和植入物之间的新骨的生长，从而将椎骨融合到植入物和彼此之间。 植入物的尺寸和形状适合于椎骨之间的空间。 在植入物的上表面和下表面上形成的齿防止植入物的短期滑动。
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公开(公告)号：US20100305704A1
公开(公告)日：2010-12-02
申请号：US12280917
申请日：2007-02-27
申请人： Dominique Messerli , Ryan T. Walsh , Brandon L. Randall , David E. Evans , Jacqueline Myer , David Koch , Markus Hunziker
发明人： Dominique Messerli , Ryan T. Walsh , Brandon L. Randall , David E. Evans , Jacqueline Myer , David Koch , Markus Hunziker
IPC分类号： A61F2/44
CPC分类号： A61F2/447 , A61B17/86 , A61F2/28 , A61F2/442 , A61F2/4455 , A61F2/4611 , A61F2002/2835 , A61F2002/30004 , A61F2002/30187 , A61F2002/30387 , A61F2002/30507 , A61F2002/30578 , A61F2002/30579 , A61F2002/30604 , A61F2002/30784 , A61F2002/30843 , A61F2002/30845 , A61F2002/30884 , A61F2002/30904 , A61F2002/4475 , A61F2220/0025 , A61F2250/0014 , A61F2310/00017 , A61F2310/00023 , A61F2310/00179 , A61F2310/00359
摘要： An intervertebral spacer implant (80) is provided with a retention mechanism (86) to help alleviate expulsion and movement of the implant when placed in the spine while providing an implant that is easier to insert in the spine. In one embodiment the retention mechanism comprises a keel on at least one of the inferior or superior faces of the spacer implant preferably extending in an anterior-posterior direction. In another embodiment the implant comprises a spacer (84) and a plate (82), the plate comprising a supplemental or alternative retention mechanism. In one embodiment the retention mechanism comprises one or more holes (88) in the anterior end of the plate. In yet another embodiment, the retention mechanism comprises one or more blades that are in a first position when inserted and are preferably rotated to a second position that engages the superior and inferior vertebrae.
摘要翻译： 椎间间隔植入物（80）设置有保持机构（86），以便当放置在脊柱中时减轻植入物的排出和移动，同时提供更容易插入脊柱的植入物。 在一个实施例中，保持机构包括在间隔件植入件的下表面或上表面中的至少一个上的龙骨，优选地在前后方向上延伸。 在另一个实施例中，植入物包括间隔物（84）和板（82），该板包括补充或替代保持机构。 在一个实施例中，保持机构包括在板的前端中的一个或多个孔（88）。 在另一个实施例中，保持机构包括一个或多个在插入时处于第一位置的叶片，并且优选地旋转到接合上下椎骨的第二位置。
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公开(公告)号：US20050113918A1
公开(公告)日：2005-05-26
申请号：US10931788
申请日：2004-09-01
CPC分类号： A61F2/28 , A61F2/4455 , A61F2002/30014 , A61F2002/30032 , A61F2002/30057 , A61F2002/30387 , A61F2002/30448 , A61F2002/30492 , A61F2002/30604 , A61F2002/30843 , A61F2002/30904 , A61F2220/0025 , A61F2220/005 , A61F2250/0018 , A61F2250/003
摘要： An allogenic implant for use in intervertebral fusion is formed from two parts. The first part, composed of cortical bone, provides mechanical strength to the implant, allowing the proper distance between the vertebrae being treated to be maintained. The second part, composed of cancellous bone, is ductile and promotes the growth of new bone between the vertebrae being treated and the implant, thus fusing the vertebrae to the implant and to each other. The implant is sized and shaped to conform to the space between the vertebrae. Teeth formed on the superior and inferior surfaces of the implant prevent short-term slippage of the implant.
摘要翻译： 用于椎间融合的同种异体植入物由两部分组成。 第一部分由皮质骨组成，为植入物提供机械强度，允许正在治疗的椎骨之间的适当距离保持不变。 由松质骨组成的第二部分是延性的并且促进正在被治疗的椎骨和植入物之间的新骨的生长，从而将椎骨融合到植入物和彼此之间。 植入物的尺寸和形状适合于椎骨之间的空间。 在植入物的上表面和下表面上形成的齿防止植入物的短期滑动。
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公开(公告)号：US20110045087A1
公开(公告)日：2011-02-24
申请号：US12666216
申请日：2009-01-30
申请人： Sean Hamilton Kerr , Ali Recber , Thomas Pepe , Dominique Messerli , Lawton Laurence , Ryan Walsh , Thomas Kueenzi , Brandon Randall
发明人： Sean Hamilton Kerr , Ali Recber , Thomas Pepe , Dominique Messerli , Lawton Laurence , Ryan Walsh , Thomas Kueenzi , Brandon Randall
CPC分类号： A61L27/56 , A61B17/86 , A61F2/4455 , A61F2002/2817 , A61F2002/30062 , A61F2002/30064 , A61F2002/3008 , A61F2002/30387 , A61F2002/30426 , A61F2002/30578 , A61F2002/30604 , A61F2002/30841 , A61F2002/3092 , A61F2002/3097 , A61F2210/0004 , A61F2220/0025 , A61F2250/0098 , A61F2310/00796 , A61F2310/00976 , A61L27/18 , A61L27/26 , A61L27/50 , A61L2430/02 , A61N1/3622 , C08G65/00 , C08J9/24 , C08J9/26
摘要： Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described include a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.
摘要翻译： 所描述的实施例包括用于形成多孔聚合物材料的装置和方法。 使用所述方法公开和形成的装置包括用于脊柱融合的间隔物，颅颌面（CMF）结构以及组织植入物的其它结构。
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公开(公告)号：US20100185290A1
公开(公告)日：2010-07-22
申请号：US12601468
申请日：2008-06-30
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61B17/7094 , A61F2/28 , A61F2/4455 , A61F2/4611 , A61F2002/30281 , A61F2002/30289 , A61F2002/30387 , A61F2002/30403 , A61F2002/30471 , A61F2002/30472 , A61F2002/30476 , A61F2002/30504 , A61F2002/30594 , A61F2002/4415 , A61F2002/444 , A61F2002/4627 , A61F2220/0025 , A61F2220/0041 , A61F2220/0091 , A61F2230/0086 , A61F2230/0091 , A61F2310/00359
摘要： A flexible chain implant for insertion into an interior volume of a vertebral body. The implant may be implanted in an insertion position for sliding through a cannula and is flexible for packing into the interior volume in an implanted configuration. The implant randomly separates in the implanted configuration. The implant includes a top member and a bottom member, wherein the top and bottom members are coupled to one another at a coupled portion. The top and bottom members preferably each include an inner surface such that the inner surfaces include a plurality of alternating projections and recesses so that the projections are received within the recesses in an insertion position. Alternatively, the implant may include a plurality of substantially non-flexible bodies and a plurality of substantially flexible links interconnecting the bodies. The non-flexible bodies include a plurality of facets and/or abutment surfaces.
摘要翻译： 用于插入椎体内部体积的柔性链植入物。 植入物可以植入插入位置以滑动通过插管，并且是柔性的，以植入构型包装到内部容积中。 植入物在植入构型中随机分离。 植入物包括顶部构件和底部构件，其中顶部构件和底部构件在联接部分处彼此联接。 顶部和底部构件优选地各自包括内表面，使得内表面包括多个交替的突起和凹部，使得突起在插入位置中容纳在凹部内。 或者，植入物可以包括多个基本上非柔性的主体和互连主体的多个基本上柔性的链接。 非柔性体包括多个面和/或邻接表面。
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公开(公告)号：US20070074980A1
公开(公告)日：2007-04-05
申请号：US11219512
申请日：2005-09-02
申请人： Brian Bankoski , David Evans , Dominique Messerli
发明人： Brian Bankoski , David Evans , Dominique Messerli
IPC分类号： B65D25/08
CPC分类号： B65D77/2024 , A61F2/0095 , B65D25/082 , B65D25/085 , B65D81/32 , B65D81/3238
摘要： Packages for the rehydration of implants are described, wherein the package may contain a first chamber containing a rehydration fluid, a second chamber containing an implant, and a barrier configured to be affected without compromising the sterility of the package. The rehydration fluid may engage and rehydrate the implant after the barrier is ruptured. Methods of use are also described.
摘要翻译： 描述了用于植入物再水合的包装，其中包装可以包含含有补液的第一室，包含植入物的第二室和被构造成受影响而不影响包装的无菌性的屏障。 补水液体可能会在屏障破裂后接合并再植入植入物。 还描述了使用方法。
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