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公开(公告)号：US10004829B2
公开(公告)日：2018-06-26
申请号：US15589212
申请日：2017-05-08
发明人： Peter H. Gingras
IPC分类号： A61L27/56 , A61K9/70 , A61F2/08 , A61F2/10 , A61F2/28 , A61F2/30 , A61L27/16 , B32B37/12 , B32B37/15 , B32B38/00 , B32B38/04 , A61F2/00 , A61F2/04 , A61F2/38 , A61F2/44 , A61F2/46
CPC分类号： A61L27/56 , A61F2/00 , A61F2/0063 , A61F2/04 , A61F2/08 , A61F2/105 , A61F2/28 , A61F2/30756 , A61F2/3872 , A61F2/442 , A61F2002/0086 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30113 , A61F2002/30125 , A61F2002/30148 , A61F2002/30154 , A61F2002/30224 , A61F2002/30225 , A61F2002/30228 , A61F2002/30448 , A61F2002/30677 , A61F2002/30762 , A61F2002/30766 , A61F2002/30785 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/30957 , A61F2002/30971 , A61F2002/4648 , A61F2210/0004 , A61F2220/005 , A61F2230/0006 , A61F2230/0008 , A61F2230/0017 , A61F2230/0021 , A61F2230/0069 , A61F2240/001 , A61F2250/0023 , A61F2250/003 , A61L27/16 , B32B37/12 , B32B37/153 , B32B38/0008 , B32B38/04 , B32B2038/042 , B32B2038/047 , B32B2367/00 , B32B2535/00 , Y10T156/1056
摘要： A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.
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公开(公告)号：US20170304058A1
公开(公告)日：2017-10-26
申请号：US15479157
申请日：2017-04-04
CPC分类号： A61F2/30756 , A61F2/38 , A61F2/44 , A61F2002/0086 , A61F2002/2817 , A61F2002/30004 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30324 , A61F2002/30677 , A61F2002/30761 , A61F2002/30762 , A61F2002/30764 , A61F2002/30766 , A61F2002/3093 , A61F2002/30971 , A61F2210/0004 , A61F2240/001 , A61F2250/0014 , A61F2250/0023 , A61F2250/003 , A61F2250/0036 , A61F2310/00365 , A61F2310/00383
摘要： An implant for repairing a cartilage defect comprising a first layer and a second layer. The first layer comprises a membrane-like structure and the second layer comprises a sponge-like structure with directional and/or interconnected pores. The first layer is facing the synovial space and the second layer is located towards bone.
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公开(公告)号：US20170266010A1
公开(公告)日：2017-09-21
申请号：US15597631
申请日：2017-05-17
申请人： P Tech, LLC
发明人： Peter M. Bonutti
IPC分类号： A61F2/38 , A61B90/92 , A61B90/94 , A61F2/00 , A61F2/46 , A61F2/82 , A61J1/03 , A61J1/18 , A61B17/06 , A61B17/80 , A61B17/86 , A61F2/28 , A61F2/30 , A61F2/32 , A61F2/40 , A61F2/42 , A61F2/44 , A61F2/48
CPC分类号： A61F2/389 , A61B17/06166 , A61B17/80 , A61B17/86 , A61B34/10 , A61B90/92 , A61B90/94 , A61B2034/108 , A61F2/0077 , A61F2/0095 , A61F2/30767 , A61F2/32 , A61F2/38 , A61F2/3804 , A61F2/3859 , A61F2/3877 , A61F2/40 , A61F2/4202 , A61F2/4261 , A61F2/44 , A61F2/461 , A61F2/4657 , A61F2/82 , A61F2002/2817 , A61F2002/30032 , A61F2002/30034 , A61F2002/30036 , A61F2002/30064 , A61F2002/30093 , A61F2002/30112 , A61F2002/30125 , A61F2002/30153 , A61F2002/30364 , A61F2002/30383 , A61F2002/30403 , A61F2002/30502 , A61F2002/30563 , A61F2002/30604 , A61F2002/30616 , A61F2002/30677 , A61F2002/3071 , A61F2002/30713 , A61F2002/30714 , A61F2002/308 , A61F2002/30878 , A61F2002/30892 , A61F2002/30909 , A61F2002/30929 , A61F2002/3093 , A61F2002/30975 , A61F2002/3863 , A61F2002/4631 , A61F2002/4632 , A61F2002/4633 , A61F2002/4658 , A61F2002/48 , A61F2210/0019 , A61F2220/0025 , A61F2220/0033 , A61F2230/0004 , A61F2230/0008 , A61F2230/0019 , A61F2240/002 , A61F2250/003 , A61F2250/0031 , A61F2250/0035 , A61F2250/0067 , A61F2250/0078 , A61F2250/0085 , A61F2250/0087 , A61F2250/0089 , A61F2310/00544 , A61F2310/00796 , A61F2310/0097 , A61J1/00 , A61J1/03 , A61J1/18 , A61J2205/20 , A61J2205/30 , A61J2205/50 , A61J2205/60
摘要： A system of prosthetic implants for a total knee replacement procedure is provided. The system includes a tibial component of a knee joint implant, a tibial insert configured to be positioned against the superior side of the platform of the tibial component, a first femoral component of a knee joint implant, and a second femoral component of a knee joint implant.
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公开(公告)号：US09592206B2
公开(公告)日：2017-03-14
申请号：US14168975
申请日：2014-01-30
申请人： AMxTek LLC
发明人： James A Walls
IPC分类号： A61F2/02 , A61K9/70 , A61K33/38 , A61K33/42 , A61L24/00 , A61L31/12 , A61L31/14 , A61L31/16 , A61L27/42 , A61L27/44 , A61F2/30 , A61F2/46 , A61L27/10 , A61B17/60 , A61B17/86 , A61F2/44
CPC分类号： A61L31/086 , A61B17/60 , A61B17/8625 , A61B17/866 , A61F2/28 , A61F2/32 , A61F2/4455 , A61F2/4644 , A61F2002/30013 , A61F2002/30032 , A61F2002/30034 , A61F2002/30036 , A61F2002/30677 , A61F2002/3068 , A61F2310/00329 , A61F2310/00359 , A61F2310/00928 , A61K9/70 , A61K33/38 , A61K33/42 , A61L24/0036 , A61L24/0042 , A61L24/0063 , A61L24/0068 , A61L24/0084 , A61L24/0089 , A61L27/10 , A61L27/425 , A61L27/427 , A61L27/446 , A61L31/022 , A61L31/082 , A61L31/123 , A61L31/124 , A61L31/127 , A61L31/128 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/104 , A61L2300/404 , A61L2300/606 , A61L2400/18 , A61L2420/04 , A61L2430/02 , A61L2430/10 , A61L2430/34
摘要： A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.
摘要翻译： 通过选择至少一种具有所需粒径和溶解度的水溶性无机材料，并将水溶性无机材料与 至少一种难溶于水或可生物降解的基质材料。 将基质材料与水溶性无机材料混合后，在组织附近放置在患者体内，使得水溶性无机材料以预定的速率溶解，以在基质材料中产生生物上希望的空隙，骨中的骨骼 或其他组织然后可以生长。
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公开(公告)号：US09545315B2
公开(公告)日：2017-01-17
申请号：US13905963
申请日：2013-05-30
申请人： Globus Medical, Inc.
发明人： Mark Borden
IPC分类号： A61F2/44 , A61F2/28 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/12 , A61L31/14 , A61B17/04 , A61B17/72 , A61B17/80 , A61B17/86 , A61B17/00 , A61F2/30
CPC分类号： A61F2/4455 , A61B17/0401 , A61B17/72 , A61B17/80 , A61B17/866 , A61B2017/00004 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2002/2835 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30069 , A61F2002/30199 , A61F2002/30622 , A61F2002/30784 , A61F2002/30925 , A61F2002/30957 , A61F2002/30968 , A61F2210/0004 , A61F2230/0063 , A61F2250/0023 , A61F2250/003 , A61F2310/00293 , A61F2310/00976 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/127 , A61L31/129 , A61L31/146 , A61L31/148 , Y10S606/907 , Y10S606/908
摘要： Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same.
摘要翻译： 具有改善的机械性能和/或降解特征的植入物，包括这种植入物的试剂盒，以及制备和使用该植入物的方法。
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公开(公告)号：US09440007B2
公开(公告)日：2016-09-13
申请号：US14450047
申请日：2014-08-01
发明人： Peter Gingras
IPC分类号： A61K9/00 , C12N5/00 , A61L27/56 , A61F2/08 , A61F2/28 , A61F2/30 , B32B38/04 , A61F2/10 , A61L27/16 , B32B37/12 , B32B37/15 , B32B38/00 , A61F2/00 , A61F2/04 , A61F2/38 , A61F2/44 , A61F2/46
CPC分类号： A61L27/56 , A61F2/00 , A61F2/0063 , A61F2/04 , A61F2/08 , A61F2/105 , A61F2/28 , A61F2/30756 , A61F2/3872 , A61F2/442 , A61F2002/0086 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30113 , A61F2002/30125 , A61F2002/30148 , A61F2002/30154 , A61F2002/30224 , A61F2002/30225 , A61F2002/30228 , A61F2002/30448 , A61F2002/30677 , A61F2002/30762 , A61F2002/30766 , A61F2002/30785 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/30957 , A61F2002/30971 , A61F2002/4648 , A61F2210/0004 , A61F2220/005 , A61F2230/0006 , A61F2230/0008 , A61F2230/0017 , A61F2230/0021 , A61F2230/0069 , A61F2240/001 , A61F2250/0023 , A61F2250/003 , A61L27/16 , B32B37/12 , B32B37/153 , B32B38/0008 , B32B38/04 , B32B2038/042 , B32B2038/047 , B32B2367/00 , B32B2535/00 , Y10T156/1056
摘要： A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.
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公开(公告)号：US20160120659A9
公开(公告)日：2016-05-05
申请号：US13905963
申请日：2013-05-30
申请人： GLOBUS MEDICAL, INC.
发明人： Mark Borden
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61B17/0401 , A61B17/72 , A61B17/80 , A61B17/866 , A61B2017/00004 , A61F2/28 , A61F2/30767 , A61F2/3094 , A61F2002/2835 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30069 , A61F2002/30199 , A61F2002/30622 , A61F2002/30784 , A61F2002/30925 , A61F2002/30957 , A61F2002/30968 , A61F2210/0004 , A61F2230/0063 , A61F2250/0023 , A61F2250/003 , A61F2310/00293 , A61F2310/00976 , A61L27/46 , A61L27/48 , A61L27/56 , A61L27/58 , A61L31/127 , A61L31/129 , A61L31/146 , A61L31/148 , Y10S606/907 , Y10S606/908
摘要： Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same.
摘要翻译： 具有改善的机械性能和/或降解特征的植入物，包括这种植入物的试剂盒，以及制备和使用该植入物的方法。
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8.发明申请公开(公告)号：US20140242044A1
公开(公告)日：2014-08-28
申请号：US14270723
申请日：2014-05-06
CPC分类号： A61F2/28 , A61B17/00491 , A61B17/06166 , A61B17/064 , A61B17/32 , A61B17/32053 , A61B17/3468 , A61B2017/0647 , A61B2034/108 , A61B2090/062 , A61F2/30756 , A61F2/3859 , A61F2/4601 , A61F2/4618 , A61F2002/2817 , A61F2002/2825 , A61F2002/2842 , A61F2002/2867 , A61F2002/30004 , A61F2002/30011 , A61F2002/30014 , A61F2002/30032 , A61F2002/30062 , A61F2002/30075 , A61F2002/3021 , A61F2002/30224 , A61F2002/30233 , A61F2002/3024 , A61F2002/30293 , A61F2002/30583 , A61F2002/30677 , A61F2002/30678 , A61F2002/30772 , A61F2002/30822 , A61F2002/30827 , A61F2002/30881 , A61F2002/30891 , A61F2002/4627 , A61F2002/4635 , A61F2002/4662 , A61F2002/4677 , A61F2002/4681 , A61F2210/0004 , A61F2210/0061 , A61F2210/0085 , A61F2230/0067 , A61F2230/0069 , A61F2230/0091 , A61F2250/0014 , A61F2250/0018 , A61F2250/0023 , A61F2250/003 , A61F2310/00179 , A61F2310/00293 , A61F2310/00365 , A61F2310/00383 , A61K33/06 , A61K33/42 , A61K38/39 , A61L27/12 , A61L27/24 , A61L27/38 , A61L27/44 , A61L27/54 , A61L27/56 , A61L27/58 , A61L31/042 , A61L31/044 , A61L31/146 , A61L31/16 , A61L2300/406 , A61L2300/414
摘要： An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant includes collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may include, or have blended in, an additive, such as an osteoinductive factor, for example biocompatible ceramics and glass.
摘要翻译： 公开了用于部署在选择位置或选择组织用于组织再生的植入物。 植入物包括胶原和/或其他生物可吸收材料，其中植入物也可用于治疗递送。 另外，植入物可以包括或掺入添加剂，例如骨诱导因子，例如生物相容性陶瓷和玻璃。
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公开(公告)号：US08796015B2
公开(公告)日：2014-08-05
申请号：US11270220
申请日：2005-11-09
申请人： Peter Gingras
发明人： Peter Gingras
IPC分类号： C12N5/00
CPC分类号： A61L27/56 , A61F2/00 , A61F2/0063 , A61F2/04 , A61F2/08 , A61F2/105 , A61F2/28 , A61F2/30756 , A61F2/3872 , A61F2/442 , A61F2002/0086 , A61F2002/30011 , A61F2002/30032 , A61F2002/30062 , A61F2002/30113 , A61F2002/30125 , A61F2002/30148 , A61F2002/30154 , A61F2002/30224 , A61F2002/30225 , A61F2002/30228 , A61F2002/30448 , A61F2002/30677 , A61F2002/30762 , A61F2002/30766 , A61F2002/30785 , A61F2002/3092 , A61F2002/3093 , A61F2002/30952 , A61F2002/30957 , A61F2002/30971 , A61F2002/4648 , A61F2210/0004 , A61F2220/005 , A61F2230/0006 , A61F2230/0008 , A61F2230/0017 , A61F2230/0021 , A61F2230/0069 , A61F2240/001 , A61F2250/0023 , A61F2250/003 , A61L27/16 , B32B37/12 , B32B37/153 , B32B38/0008 , B32B38/04 , B32B2038/042 , B32B2038/047 , B32B2367/00 , B32B2535/00 , Y10T156/1056
摘要： A tissue scaffold includes a first film having a plurality of cell openings and a second film adjacent the first film and having a plurality of cell openings larger than the cell openings of the first film. The cell openings of the first film interconnect with the cell openings of the second film to define pathways extending through the first and second films.
摘要翻译： 组织支架包括具有多个电池开口的第一膜和与第一膜相邻的第二膜，并且具有大于第一膜的电池开口的多个电池开口。 第一膜的电池开口与第二膜的电池开口互连，以限定延伸穿过第一和第二膜的路径。
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公开(公告)号：US20140147487A1
公开(公告)日：2014-05-29
申请号：US14168975
申请日：2014-01-30
申请人： AMxTek LLC
发明人： James A. Walls
CPC分类号： A61L31/086 , A61B17/60 , A61B17/8625 , A61B17/866 , A61F2/28 , A61F2/32 , A61F2/4455 , A61F2/4644 , A61F2002/30013 , A61F2002/30032 , A61F2002/30034 , A61F2002/30036 , A61F2002/30677 , A61F2002/3068 , A61F2310/00329 , A61F2310/00359 , A61F2310/00928 , A61K9/70 , A61K33/38 , A61K33/42 , A61L24/0036 , A61L24/0042 , A61L24/0063 , A61L24/0068 , A61L24/0084 , A61L24/0089 , A61L27/10 , A61L27/425 , A61L27/427 , A61L27/446 , A61L31/022 , A61L31/082 , A61L31/123 , A61L31/124 , A61L31/127 , A61L31/128 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/104 , A61L2300/404 , A61L2300/606 , A61L2400/18 , A61L2420/04 , A61L2430/02 , A61L2430/10 , A61L2430/34
摘要： A method for controlling generation of biologically desirable voids in a composition placed in proximity to bone or other tissue in a patient by selecting at least one water-soluble inorganic material having a desired particle size and solubility, and mixing the water-soluble inorganic material with at least one poorly-water-soluble or biodegradable matrix material. The matrix material, after it is mixed with the water-soluble inorganic material, is placed into the patient in proximity to tissue so that the water-soluble inorganic material dissolves at a predetermined rate to generate biologically desirable voids in the matrix material into which bone or other tissue can then grow.
摘要翻译： 通过选择至少一种具有所需粒径和溶解度的水溶性无机材料，并将水溶性无机材料与 至少一种难溶于水或可生物降解的基质材料。 将基质材料与水溶性无机材料混合后，在组织附近放置在患者体内，使得水溶性无机材料以预定的速率溶解，以在基质材料中产生生物上希望的空隙，骨中的骨骼 或其他组织然后可以生长。
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