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    MICROFLUIDIC ELASTIC MICRO-ALIQUOTTER
    1.
    发明申请
    MICROFLUIDIC ELASTIC MICRO-ALIQUOTTER 有权
    微流体弹性微型铝合金

    公开(公告)号：US20100077875A1

    公开(公告)日：2010-04-01

    申请号：US12240169

    申请日：2008-09-29

    Applicant: Donald R. Moles

    Inventor： Donald R. Moles

    IPC: G01N1/10 ,  B01J19/00 ,  G01N1/14

    CPC classification number: B01L3/5027 ,  B01L2200/0605 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0487 ,  G01N2035/1032

    Abstract: Disclosed is a microfluidic device comprising at least one micro-aliquotter for dispensing fixed or variable volumes. The micro-aliquotter includes an rigid, dimensionally stable foundational layer having a fluid port therein that is in fluid communication with a channel within the microfluidic device, and an elastic film positioned on the foundational layer where the film covers the fluid port. The elastic film is sealed to the foundational layer so fluids entering through the fluid port can be captured between the elastic film and the foundational layer. The elastic film being expandable from a rest position on the foundational layer to a dispensing, or aliquotting, position in which an aliquot volume of a fluid is contained between the film and the foundational layer.

    Abstract translation: 公开了一种微流体装置，其包括用于分配固定或可变体积的至少一个微等分。 微等分液体包括刚性的尺寸稳定的基础层，其中具有与微流体装置内的通道流体连通的流体端口，以及位于膜覆盖流体端口的基础层上的弹性膜。 弹性膜被密封到基础层，使得通过流体口进入的流体可以被捕获在弹性膜和基础层之间。 弹性膜可从基础层上的静止位置扩展到分配或等分的位置，其中在膜和基础层之间容纳流体的等分体积体积。

    Method of making a platform for use in a sensor in a microfluidic device
    4.
    发明授权
    Method of making a platform for use in a sensor in a microfluidic device 有权
    制造用于微流体装置中的传感器的平台的方法

    公开(公告)号：US06770322B1

    公开(公告)日：2004-08-03

    申请号：US09799820

    申请日：2001-03-02

    Applicant: Donald R. Moles

    Inventor： Donald R. Moles

    IPC: B05D722

    CPC classification number: C12Q1/001

    Abstract: A method is provided for constructing a platform for use in a sensor in a microfluidic device. The method may include the steps of selecting a polymeric film, laser drilling at least one frustoconical pore in the film, depositing a layer of metal suitable for use as an electrode over a wall of the pore, and depositing a membrane capable of detecting an analyte in the pore over the metal layer. The method may also include the additional step of forming a diffusion limiting layer in the pore at an exit end of the pore before depositing the membrane capable of detecting an analyte.

    Abstract translation: 提供了一种构造用于微流体装置中的传感器的平台的方法。 该方法可以包括以下步骤：选择聚合物膜，在膜中激光钻取至少一个截头圆锥孔，在孔的壁上沉积适合用作电极的金属层，以及沉积能够检测分析物的膜 在金属层上的孔中。 该方法还可以包括在沉积能够检测分析物的膜的孔的出口端处的孔中形成扩散限制层的附加步骤。

    Microstructured bilateral sensor
    5.
    发明授权
    Microstructured bilateral sensor 有权
    微结构双边传感器

    公开(公告)号：US06551496B1

    公开(公告)日：2003-04-22

    申请号：US09800438

    申请日：2001-03-06

    Applicant: Donald R. Moles ,  Quinn Leland ,  Marcel Madaras

    Inventor： Donald R. Moles ,  Quinn Leland ,  Marcel Madaras

    IPC: G01N27327

    CPC classification number: C12Q1/001

    Abstract: A bilateral biosensor based upon a microporous architecture is provided which seeks to reduce the effect of co-reactant concentration limitations by utilizing a new sensor microgeometry. If implemented on the appropriate scale, the new sensor design augments substantially the concentration of oxygen, or other co-reactants or reagents, in the reaction zone of the sensor. Performance enhancements over traditional microscale devices employing unilateral orientation are accomplished, in one embodiment, by allowing analyte to enter the sensor from one side of the sensor, while allowing a co-substrate to enter from both sides of the sensor.

    Abstract translation: 提供了基于微孔结构的双边生物传感器，其旨在通过利用新的传感器微尺度法来减少共反应物浓度限制的影响。 如果以适当的规模实施，新的传感器设计在传感器的反应区域基本上增加了氧气或其他共反应物或试剂的浓度。 在一个实施例中，通过允许分析物从传感器的一侧进入传感器，同时允许共基板从传感器的两侧进入，实现了超过使用单侧取向的传统微型设备的性能增强。

    Arc reactor device
    8.
    发明授权
    Arc reactor device 失效
    电弧反应器装置

    公开(公告)号：US4256967A

    公开(公告)日：1981-03-17

    申请号：US60537

    申请日：1979-07-25

    Applicant: Richard W. Treharne ,  Charlton K. McKibben ,  Donald R. Moles ,  Mitchell R. M. Bruce

    Inventor： Richard W. Treharne ,  Charlton K. McKibben ,  Donald R. Moles ,  Mitchell R. M. Bruce

    IPC: B01J12/00 ,  B01J19/08 ,  C01B21/32

    CPC classification number: C01B21/32 ,  B01J12/002 ,  B01J19/088 ,  Y10S422/904

    Abstract: An arc reactor device for producing nitrogen oxides by an arc discharge process includes an electrically conductive casing, defining an arc discharge chamber therein, and an electrically conductive discharge electrode electrically insulated from the casing and extending into the chamber. An arc discharge potential is applied between the discharge electrode and the casing to produce electrical arcing. A starter electrode extends into the chamber and is movable from an extended position in which it contacts the discharge electrode, to a retracted position, in which the starter electrode is out of contact with the discharge electrode. A means for moving the starter electrode from the extended position, at initiation of operation, to the retracted position and maintaining the starter electrode in the retracted position during operation of the arc reactor device includes a solenoid actuator. Air is supplied to the electrically conductive casing from several manifolds which surround the casing. A plurality of orifices extend between manifold chambers, defined by the manifolds, and the discharge chamber with the orifices producing a nonturbulent spiral flow of air in the discharge chamber.

    Abstract translation: 用于通过电弧放电工艺生产氮氧化物的电弧反应器装置包括在其中限定电弧放电室的导电外壳和与壳体电绝缘并延伸到腔室中的导电放电电极。 在放电电极和壳体之间施加电弧放电电位以产生电弧。 起动电极延伸到室中并且可以从其与放电电极接触的延伸位置移动到缩回位置，在该缩回位置，起动电极与放电电极不接触。 一种用于在启动操作时将起动电极从延伸位置移动到缩回位置并且在电弧反应器装置的操作期间将起动电极维持在缩回位置的装置包括螺线管致动器。 空气从围绕壳体的多个歧管供应到导电壳体。 多个孔在由歧管限定的歧管室之间延伸，并且具有孔的排出室在排放室中产生非湍流的螺旋空气流。

    Microfluidic module including an adhesiveless self-bonding rebondable polyimide
    9.
    发明授权
    Microfluidic module including an adhesiveless self-bonding rebondable polyimide 有权
    微流控模块包括无粘合剂自粘性可重聚聚酰亚胺

    公开(公告)号：US08137641B2

    公开(公告)日：2012-03-20

    申请号：US13028550

    申请日：2011-02-16

    Applicant: Donald R. Moles

    Inventor： Donald R. Moles

    IPC: C03C25/68 ,  B32B38/10 ,  B32B37/02

    CPC classification number: B01L3/502707 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0627 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/12 ,  Y10T156/10

    Abstract: A method of making a microfluidic module is disclosed that includes forming a fluid flow channel in a self-bonding rebondable polyimide film to provide a channel sheet, the self-bonding rebondable polyimide film having a first mask layer self-bonded thereto; removing the first mask layer from the channel sheet after forming the fluid flow channel; and self-bonding the surface of the channel sheet exposed by removal of the first mask layer to a cover sheet.

    Abstract translation: 公开了一种制造微流体模块的方法，其包括在自粘可折射聚酰亚胺膜中形成流体流动通道以提供通道片，所述自粘合可折射聚酰亚胺膜具有与其自身结合的第一掩模层; 在形成流体流动通道之后，从通道片中去除第一掩模层; 并且通过去除第一掩模层而将通道片的表面自粘结到覆盖片。

    Microfluidic elastic micro-aliquotter
    10.
    发明授权
    Microfluidic elastic micro-aliquotter 有权
    微流体弹性微等分

    公开(公告)号：US08082810B2

    公开(公告)日：2011-12-27

    申请号：US12240169

    申请日：2008-09-29

    Applicant: Donald R. Moles

    Inventor： Donald R. Moles

    IPC: G01N1/14

    CPC classification number: B01L3/5027 ,  B01L2200/0605 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0487 ,  G01N2035/1032

    Abstract: Disclosed is a microfluidic device comprising at least one micro-aliquotter for dispensing fixed or variable volumes. The micro-aliquotter includes an rigid, dimensionally stable foundational layer having a fluid port therein that is in fluid communication with a channel within the microfluidic device, and an elastic film positioned on the foundational layer where the film covers the fluid port. The elastic film is sealed to the foundational layer so fluids entering through the fluid port can be captured between the elastic film and the foundational layer. The elastic film being expandable from a rest position on the foundational layer to a dispensing, or aliquotting, position in which an aliquot volume of a fluid is contained between the film and the foundational layer.

    Abstract translation: 公开了一种微流体装置，其包括用于分配固定或可变体积的至少一个微等分。 微等分液体包括刚性的尺寸稳定的基础层，其中具有与微流体装置内的通道流体连通的流体端口，以及位于膜覆盖流体端口的基础层上的弹性膜。 弹性膜被密封到基础层，使得通过流体口进入的流体可以被捕获在弹性膜和基础层之间。 弹性膜可从基础层上的静止位置扩展到分配或等分的位置，其中在膜和基础层之间容纳流体的等分体积体积。

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