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    Tissue heating and ablation systems and methods using self-heated electrodes
    3.
    发明授权
    Tissue heating and ablation systems and methods using self-heated electrodes 失效
    组织加热和消融系统和使用自热电极的方法

    公开(公告)号：US6022346A

    公开(公告)日：2000-02-08

    申请号：US480138

    申请日：1995-06-07

    申请人： Dorin Panescu ,  Sidney D. Fleischman ,  David K. Swanson

    发明人： Dorin Panescu ,  Sidney D. Fleischman ,  David K. Swanson

    IPC分类号： A61B18/12 ,  A61B18/14 ,  A61N1/40 ,  A61B17/39

    CPC分类号： A61B18/1206 ,  A61B18/1492 ,  A61N1/403 ,  A61B18/1402 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00791 ,  A61B2018/00803

    摘要： Systems and methods using an electrode able to transmit heating or ablation energy into tissue include first and second sensing elements associated with the electrode for measuring first and second temperatures. The electrode also includes a heating element in thermal conductive contact with the electrode for heating the electrode. The systems and methods sequentially activate the heating element and sense temperatures without transmitting tissue heating or ablation energy, and then transmit heating or ablation energy and sense temperatures without activating the heating element, to derive from the sensed temperatures a prediction of maximum tissue temperature.

    摘要翻译： 使用能够将加热或消融能量传递到组织中的电极的系统和方法包括与用于测量第一和第二温度的电极相关联的第一和第二感测元件。 电极还包括与用于加热电极的电极导热接触的加热元件。 系统和方法顺序地激活加热元件并且感测温度而不传递组织加热或消融能量，然后传递加热或消融能量并感测温度而不激活加热元件，从感测的温度导出最大组织温度的预测。

    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions
    4.
    发明授权
    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions 失效
    使用具有不对称机械性能的结构以支持与内部身体区域中的组织接触的诊断或治疗元件的系统和方法

    公开(公告)号：US6014590A

    公开(公告)日：2000-01-11

    申请号：US742564

    申请日：1996-10-28

    申请人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    发明人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    IPC分类号： A61B17/39

    摘要： Structures having asymmetric mechanical properties provide enhanced ability to support therapeutic or diagnostic elements in contact with tissue in an interior body region. The support structure includes a first region, which exhibits a first mechanical property affecting tissue contact, and a second region spaced from the first region about the axis, which exhibits a second mechanical property, different than the first mechanical property, affecting tissue contact. In a preferred embodiment, the first and second mechanical properties correlate with stiffness of the respective first and second regions, with the first region being more flexible (i.e., less stiff) than the second region. The first region, due to its greater flexibility, is more conformal to tissue than the second region. The less flexible (i.e., more stiff) second region imparts greater force against the tissue to urge the more flexible first region toward intimate tissue contact. In a preferred embodiment, the more flexible first region carries at least one therapeutic or diagnostic element.

    摘要翻译： 具有不对称机械特性的结构提供增强的能力，以支持与内部身体区域中的组织接触的治疗或诊断元件。 支撑结构包括表现出影响组织接触的第一机械特性的第一区域以及围绕轴线与第一区域隔开的第二区域，该第二区域具有影响组织接触的第二机械特性，该第二机械特性不同于第一机械特性。 在优选实施例中，第一和第二机械特性与相应的第一和第二区域的刚度相关，其中第一区域比第二区域更加柔性（即，较不硬）。 第一个区域由于其更大的灵活性，比第二个区域更适合组织。 较不柔性（即更硬）的第二区域赋予组织更大的力以促使更柔性的第一区域朝向紧密的组织接触。 在优选实施方案中，更灵活的第一区域携带至少一种治疗或诊断元件。

    Systems and methods using asymmetric multiple electrode arrays
    8.
    发明授权
    Systems and methods using asymmetric multiple electrode arrays 失效
    使用不对称多电极阵列的系统和方法

    公开(公告)号：US5968040A

    公开(公告)日：1999-10-19

    申请号：US728698

    申请日：1996-10-28

    申请人： David K. Swanson ,  Sidney D. Fleischman ,  Dorin Panescu ,  James G. Whayne ,  Thomas F. Kordis

    发明人： David K. Swanson ,  Sidney D. Fleischman ,  Dorin Panescu ,  James G. Whayne ,  Thomas F. Kordis

    IPC分类号： A61N1/00 ,  A61B17/39

    CPC分类号： A61N1/00

    摘要： Systems and methods support arrays of multiple electrodes in asymmetric pattern, either radially, or axially, or both. Radial asymmetry makes it possible provide localized density of electrodes. Axial asymmetry makes it possible to locate electrodes in a pattern that closely conforms to the irregular contours of an interior body cavity, like the heart. In a preferred embodiment, the systems and methods operate the multiple electrode arrays to form continuous lesion patterns.

    摘要翻译： 系统和方法以径向或轴向或两者不对称的方式支持多个电极的阵列。 径向不对称使得可能提供电极的局部密度。 轴向不对称使得可以将电极定位成与内部体腔的不规则轮廓紧密一致的图案，如心脏。 在优选实施例中，系统和方法操作多个电极阵列以形成连续的病变图案。

    Tissue heating and ablation systems and methods which predict maximum tissue temperature
    10.
    发明授权
    Tissue heating and ablation systems and methods which predict maximum tissue temperature 失效
    组织加热和消融系统和预测最大组织温度的方法

    公开(公告)号：US06293943B1

    公开(公告)日：2001-09-25

    申请号：US09034977

    申请日：1998-03-04

    申请人： Dorin Panescu ,  Sidney D. Fleischman ,  David K. Swanson

    发明人： Dorin Panescu ,  Sidney D. Fleischman ,  David K. Swanson

    IPC分类号： A61B1739

    CPC分类号： A61B18/1206 ,  A61B18/1402 ,  A61B18/1492 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00791 ,  A61B2018/00803 ,  A61N1/403

    摘要： Systems and methods heat or ablate body tissue by positioning an electrode to transmit heat or ablation energy to a tissue region. The systems and methods measure a first temperature using a temperature sensing element associated with the electrode. The systems and methods also measure a second temperature using a temperature sensing element associated with the electrode. The systems and methods process at least one of the first and second temperatures to derive a prediction of maximum temperature of the tissue region. The systems and methods generate an output that controls the transmission of the heating or ablation energy based, at least in part, upon the maximum tissue temperature prediction.

    摘要翻译： 系统和方法通过将电极定位以将热量或消融能量传递到组织区域来加热或消融身体组织。 系统和方法使用与电极相关联的温度感测元件来测量第一温度。 系统和方法还使用与电极相关联的温度感测元件测量第二温度。 系统和方法处理第一和第二温度中的至少一个以导出组织区域的最大温度的预测。 系统和方法至少部分地基于最大组织温度预测产生控制加热或消融能量传递的输出。