-
公开(公告)号:US12186183B2
公开(公告)日:2025-01-07
申请号:US17485154
申请日:2021-09-24
Applicant: Edwards Lifesciences Corporation
Inventor: Michael J. Popp , David Alon , Jun Liu , Luca Pesce , Mohammad Jafari
Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
-
公开(公告)号:US09498202B2
公开(公告)日:2016-11-22
申请号:US13938071
申请日:2013-07-09
Applicant: Edwards Lifesciences Corporation
Inventor: Mohammad Jafari , Ming H. Wu , Hengchu Cao , Ralph Schneider , Manouchehr A. Miraki
IPC: A61B17/04 , A61B17/064 , A61F2/08 , B65D33/16 , A61F2/24
CPC classification number: A61B17/0401 , A61B17/0487 , A61B17/0642 , A61B2017/0404 , A61B2017/0406 , A61B2017/0419 , A61B2017/042 , A61B2017/0437 , A61B2017/0438 , A61B2017/0446 , A61B2017/0448 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/049 , A61F2/0811 , A61F2/2448 , B65D33/1625 , Y10T24/155 , Y10T24/44923
Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.
Abstract translation: 这里公开了缝合线固定装置的示例性实施例,其代替在缝合线中结扎的需要。 一些实施例包括环形外体和从外体向内延伸的一个或多个缝合线接合片。 该装置可以包括超弹性和/或形状记忆材料,并且具有大致平面的初始构型。 缝合线接合部分可以在平面外成形为活动构型,外部主体被压缩,并且翼片彼此互锁。 该设备可以在变形的配置中进行热定形。 互锁的舌片在通过它们之间的缝合线上施加夹紧力,其限制缝合线在一个纵向方向上滑动通过开口。
-
公开(公告)号:US11129713B2
公开(公告)日:2021-09-28
申请号:US17077860
申请日:2020-10-22
Applicant: Edwards Lifesciences Corporation
Inventor: Michael J. Popp , David Alon , Jun Liu , Luca Pesce , Mohammad Jafari
Abstract: A prosthetic heart valve delivery system can include a catheter portion having a sheath that can cover and uncover the prosthetic heart valve mounted on an inner shaft, a handle having a sheath actuator operatively coupled to a proximal portion of the sheath, the inner shaft extending through the handle, and a shaft retractor releasably coupled to a proximal portion of the handle and fixedly coupled to a proximal portion of the inner shaft. A sheath actuator can move the sheath axially relative to the inner shaft when the shaft retractor is coupled to the handle, and a proximal movement of the sheath relative to the inner shaft can cause the sheath to uncover the prosthetic heart valve. The shaft retractor can be operable to retract the inner shaft and the nosecone proximally relative to the sheath when the shaft retractor is released from the handle.
-
公开(公告)号:USRE47209E1
公开(公告)日:2019-01-22
申请号:US15499611
申请日:2017-04-27
Applicant: Edwards Lifesciences Corporation
Inventor: Mohammad Jafari , Ming H. Wu , Hengchu Cao , Ralph Schneider , Manouchehr A. Miraki
IPC: A61B17/04 , A61B17/064
Abstract: Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction.
-
公开(公告)号:US20190000615A1
公开(公告)日:2019-01-03
申请号:US16034794
申请日:2018-07-13
Applicant: Edwards Lifesciences Corporation
Inventor: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ofir Witzman , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eason Michael Abbott , Dustin P. Armer , Michael D. Franklin , Tomer Saar , Anatoly Dvorsky , John J. Desrosiers , Daniel James Murray , Michael G. Valdez , Assaf Bash , Amir Blumenfeld , Noa Axelrod , Eitan Atias
IPC: A61F2/24
Abstract: Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.
-
公开(公告)号:US11737868B2
公开(公告)日:2023-08-29
申请号:US16783005
申请日:2020-02-05
Applicant: Edwards Lifesciences Corporation
Inventor: Michael J. Popp , David Alon , Jun Liu , Luca Pesce , Mohammad Jafari
CPC classification number: A61F2/2427 , A61F2/0095 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/915 , A61F2/9517 , A61F2/9522 , A61F2002/9155 , A61F2002/9665 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2230/0069 , A61M25/0051
Abstract: A handle for a prosthetic heart valve delivery apparatus includes a housing, a motorized mechanism, and a holding mechanism. The housing is configured to be hand-held by a user and includes a distal opening. The motorized mechanism is disposed within the housing and is configured to be releasably coupled to a proximal end portion of a first shaft of the prosthetic heart valve delivery apparatus. When actuated, the motorized mechanism is configured to rotate the first shaft relative to the housing. The holding mechanism is disposed inside the housing and is configured to engage a proximal end portion of a second shaft of the prosthetic heart valve delivery apparatus such that the second shaft is axially and rotationally fixed relative to the housing, and the first shaft extends through the second shaft.
-
公开(公告)号:US20210038385A1
公开(公告)日:2021-02-11
申请号:US17077860
申请日:2020-10-22
Applicant: Edwards Lifesciences Corporation
Inventor: Michael J. Popp , David Alon , Jun Liu , Luca Pesce , Mohammad Jafari
Abstract: A prosthetic heart valve delivery system can include a catheter portion having a sheath that can cover and uncover the prosthetic heart valve mounted on an inner shaft, a handle having a sheath actuator operatively coupled to a proximal portion of the sheath, the inner shaft extending through the handle, and a shaft retractor releasably coupled to a proximal portion of the handle and fixedly coupled to a proximal portion of the inner shaft. A sheath actuator can move the sheath axially relative to the inner shaft when the shaft retractor is coupled to the handle, and a proximal movement of the sheath relative to the inner shaft can cause the sheath to uncover the prosthetic heart valve. The shaft retractor can be operable to retract the inner shaft and the nosecone proximally relative to the sheath when the shaft retractor is released from the handle.
-
公开(公告)号:US10470876B2
公开(公告)日:2019-11-12
申请号:US15345857
申请日:2016-11-08
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Mohammad Jafari , Liron Tayeb , Ilan Tamir , Ziv Yohanan , Noam Nir , David Maimon , Boaz Manash
IPC: A61F2/24
Abstract: Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion. The prosthetic valve may further comprise one or more ventricular anchors coupled to the main body and disposed outside of the main body. The ventricular anchors may be configured such that a reduced profile of the prosthetic valve is possible. A space may be provided between an outer surface of the main body and the ventricular anchors for receiving native mitral valve leaflets. The prosthetic valve may include an atrial sealing member adapted for placement above the annulus of the mitral valve. Methods and devices for receiving the native mitral valve leaflets between the ventricular anchors and the main body are described.
-
公开(公告)号:US20250120808A1
公开(公告)日:2025-04-17
申请号:US18988463
申请日:2024-12-19
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Michael J. Popp , David Alon , Jun Liu , Luca Pesce , Mohammad Jafari
Abstract: Certain embodiments of the present disclosure provide a prosthetic valve (e.g., prosthetic heart valve) and a valve delivery apparatus for delivery of the prosthetic valve to a native valve site via the human vasculature. The delivery apparatus is particularly suited for advancing a prosthetic heart valve through the aorta (i.e., in a retrograde approach) for replacing a diseased native aortic valve. The delivery apparatus in particular embodiments is configured to deploy a prosthetic valve from a delivery sheath in a precise and controlled manner at the target location within the body.
-
公开(公告)号:US12186184B2
公开(公告)日:2025-01-07
申请号:US17657732
申请日:2022-04-01
Applicant: Edwards Lifesciences Corporation
Inventor: Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eitan Atias
Abstract: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.
-
-
-
-
-
-
-
-
-