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    Dual-wireform limited expansion heart valves
    1.
    发明授权
    Dual-wireform limited expansion heart valves 有权

    公开(公告)号：US11135057B2

    公开(公告)日：2021-10-05

    申请号：US16721727

    申请日：2019-12-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： Derrick Johnson ,  Michael C. Murad ,  Steven M. Ford ,  Rodolfo Rodriguez

    IPC: A61F2/24

    Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein. A dual-wireform support frame including an upper and a lower wireform permits expansion of the valve by one or two valve sizes, for example, with a 2-mm gap between each valve size. The lower wireform has a relatively shallow undulation so that it may stretch apart by a small amount and then prevent further expansion of the valve.

    MINIMALLY-INVASIVE LOW STRAIN ANNULOPLASTY RING
    3.
    发明申请
    MINIMALLY-INVASIVE LOW STRAIN ANNULOPLASTY RING 有权

    公开(公告)号：US20230125047A1

    公开(公告)日：2023-04-20

    申请号：US18069082

    申请日：2022-12-20

    Applicant: Edwards Lifesciences Corporation

    Inventor： Brian S. Conklin ,  Louis A. Campbell ,  Salvador Marquez ,  James R. Yamada ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Steven M. Ford

    IPC: A61F2/24

    Abstract: A minimally-invasive annuloplasty ring for implant at a mitral annulus. The annuloplasty ring has an inner core member with a C-shaped plan view that generally defines an oval with a major axis and a minor axis, and is symmetric about the minor axis. A posterior portion of the core member bisected by the minor axis has a thicker radial dimension than a pair of free end regions terminating on an anterior side of the core member. The radial thickness smoothly transitions between the posterior portion and the end regions. The inner core member may be covered with a fabric, and is a superelastic metal so that it can be straightened out and delivered through an access tube. The curvatures and thicknesses around the core member are selected so that the strain experienced when straightened does not exceed 7-8%.

    ENHANCED FLEXIBILITY ANNULOPLASTY BANDS
    4.
    发明申请
    ENHANCED FLEXIBILITY ANNULOPLASTY BANDS 有权

    公开(公告)号：US20220370200A1

    公开(公告)日：2022-11-24

    申请号：US17817231

    申请日：2022-08-03

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rodolfo Rodriguez ,  Brian S. Conklin ,  Louis A. Campbell

    IPC: A61F2/24

    Abstract: An annuloplasty band having a differentiation in area moment of inertia, where the area moment of inertia in the out of plane direction is much less than the area moment of inertia in the plane of the annulus. This makes the band stiff enough to hold the annulus in the correct shape while being flexible enough out of plane to minimize the risk of suture dehiscence or breakage. One example is a C-shaped band with a core formed of nitinol and having a constant cross-section with a wider radial dimension than an axial dimension. The cross-section may be rectangular. The band is asymmetric across a minor axis with one end extending around the anterior side farther than the other. The free ends rise up from adjacent lateral sides, and a continuous posterior mid-section also rises upward.

    HIGH DURABILITY HEART VALVE
    5.
    发明申请
    HIGH DURABILITY HEART VALVE 有权
    高耐久性心脏瓣膜

    公开(公告)号：US20150282929A1

    公开(公告)日：2015-10-08

    申请号：US14677746

    申请日：2015-04-02

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rodolfo Rodriguez

    IPC: A61F2/24 ,  C23C14/06 ,  C23C16/44 ,  C23C16/34 ,  C23C14/24 ,  C23C14/32

    CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2210/0076 ,  C23C14/0021 ,  C23C14/025 ,  C23C14/0641 ,  C23C14/16 ,  C23C14/24 ,  C23C14/325 ,  C23C16/34 ,  C23C16/44 ,  Y10T29/49885 ,  Y10T29/49982

    Abstract: An improved heart bioprosthetic device having a metal frame wireform or stent having an outer external surface. The metal frame has a bond layer coating at least a portion of the external surface and a coating layer disposed on at least a portion of the bond layer. The bond layer comprises a metal selected from the group consisting of: chromium, titanium, zirconium, aluminum, platinum, palladium, and niobium. The coating layer is selected from the group consisting of: a metal nitride, a metal oxide, a metal carbide, and combinations thereof. The coating layer may have a thickness of about 10 μm or less and a grain size of about 10 nm to about 15 nm, and may be characterized as polycrystalline with randomly-oriented grains with both cubic and orthorhombic phases. In one embodiment, the bond layer comprises chromium and the coating layer comprises chromium nitride.

    Abstract translation: 一种改进的心脏生物假体装置，其具有具有外部外表面的金属框架线形或支架。 金属框架具有涂覆外表面的至少一部分的接合层和设置在接合层的至少一部分上的涂层。 所述接合层包含选自铬，钛，锆，铝，铂，钯和铌的金属。 涂层选自：金属氮化物，金属氧化物，金属碳化物及其组合。 涂层可以具有约10μm以下的厚度和约10nm至约15nm的晶粒尺寸，并且可以表征为具有立方晶相和正交晶相的随机取向晶粒的多晶。 在一个实施方案中，接合层包含铬，并且涂层包含氮化铬。

    System and method for implanting and securing a bioprosthetic device to wet tissue
    6.
    发明授权
    System and method for implanting and securing a bioprosthetic device to wet tissue 有权

    公开(公告)号：US11382738B2

    公开(公告)日：2022-07-12

    申请号：US16570797

    申请日：2019-09-13

    Applicant: Edwards Lifesciences Corporation

    Inventor： Bin Tian ,  Rodolfo Rodriguez ,  Louis A. Campbell ,  Steven M. Claessens ,  Carolyn Sue Martinez

    IPC: A61F2/24

    Abstract: Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.

    Method for manufacturing high durability heart valve
    7.
    发明授权
    Method for manufacturing high durability heart valve 有权
    制造高耐久性心脏瓣膜的方法

    公开(公告)号：US09549816B2

    公开(公告)日：2017-01-24

    申请号：US14677746

    申请日：2015-04-02

    Applicant: Edwards Lifesciences Corporation

    Inventor： Rodolfo Rodriguez

    IPC: A61F2/24 ,  C23C14/06 ,  C23C14/24 ,  C23C14/32 ,  C23C16/34 ,  C23C16/44 ,  C23C14/02

    CPC classification number: A61F2/2418 ,  A61F2/24 ,  A61F2/2412 ,  A61F2/2415 ,  A61F2210/0076 ,  C23C14/0021 ,  C23C14/025 ,  C23C14/0641 ,  C23C14/16 ,  C23C14/24 ,  C23C14/325 ,  C23C16/34 ,  C23C16/44 ,  Y10T29/49885 ,  Y10T29/49982

    Abstract: An improved heart bioprosthetic device having a metal frame wireform or stent having an outer external surface. The metal frame has a bond layer coating at least a portion of the external surface and a coating layer disposed on at least a portion of the bond layer. The bond layer comprises a metal selected from the group consisting of: chromium, titanium, zirconium, aluminum, platinum, palladium, and niobium. The coating layer is selected from the group consisting of: a metal nitride, a metal oxide, a metal carbide, and combinations thereof. The coating layer may have a thickness of about 10 μm or less and a grain size of about 10 nm to about 15 nm, and may be characterized as polycrystalline with randomly-oriented grains with both cubic and orthorhombic phases. In one embodiment, the bond layer comprises chromium and the coating layer comprises chromium nitride.

    Abstract translation: 一种改进的心脏生物假体装置，其具有具有外部外表面的金属框架线形或支架。 金属框架具有涂覆外表面的至少一部分的接合层和设置在接合层的至少一部分上的涂层。 所述接合层包含选自铬，钛，锆，铝，铂，钯和铌的金属。 涂层选自：金属氮化物，金属氧化物，金属碳化物及其组合。 涂层可以具有约10μm以下的厚度和约10nm至约15nm的晶粒尺寸，并且可以表征为具有立方晶相和正交晶相的随机取向晶粒的多晶。 在一个实施方案中，接合层包含铬，并且涂层包含氮化铬。

    EXPANDABLE ANNULOPLASTY RINGS
    9.
    发明公开
    EXPANDABLE ANNULOPLASTY RINGS 审中-公开

    公开(公告)号：US20230181320A1

    公开(公告)日：2023-06-15

    申请号：US18167720

    申请日：2023-02-10

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： Louis A. Campbell ,  Rodolfo Rodriguez ,  Da-Yu Chang ,  Gregory Bak-Boychuk ,  Brian S. Conklin ,  Amy E. Munnelly

    IPC: A61F2/24

    CPC classification number: A61F2/2448 ,  A61F2250/0029 ,  A61F2250/0036

    Abstract: A mitral repair annuloplasty ring that will accommodate implantation of a transcatheter valve therein for a valve-in-ring reoperation. The ring has a semi-rigid core with features that allow the ring to better conform to the cylindrical geometry of a transcatheter valve when implanted. The inner core defines a continuous peripheral D-shape with a substantially straight anterior side diametrically across from a more rounded posterior side with arcuate lateral sides therebetween. Segments of the ring core are subject to differing rates of bending due to variable radial thicknesses or radial slits opening to both inner and outer edges around the core periphery. One or more expansion joints may also be used to create the more circular final expanded shape. A plastically expandable sealing sleeve may surround the transcatheter valve for sealing gaps between the valve and annuloplasty ring.

    SYSTEM AND METHOD FOR IMPLANTING AND SECURING A BIOPROSTHETIC DEVICE TO WET TISSUE
    10.
    发明申请
    SYSTEM AND METHOD FOR IMPLANTING AND SECURING A BIOPROSTHETIC DEVICE TO WET TISSUE 有权

    公开(公告)号：US20220338982A1

    公开(公告)日：2022-10-27

    申请号：US17811545

    申请日：2022-07-08

    Applicant: Edwards Lifesciences Corporation

    Inventor： Bin Tian ,  Rodolfo Rodriguez ,  Louis A. Campbell ,  Steven M. Claessens ,  Carolyn Sue Martinez

    IPC: A61F2/24

    Abstract: Systems, devices, kits, and methods are described for securing a bioprosthetic heart valve within an anatomical feature of a patient. Kits can comprise a bioprosthetic heart valve, a curable composition, and an applicator configured to deliver the curable composition to a target area. The bioprosthetic heart valve can comprise a support structure and one or more valve leaflets coupled thereto. The support structure can comprise a sewing portion peripheral of the bioprosthetic heart valve. The support structure and the valve leaflets can define a central flow orifice. The curable composition can comprise a pre-polymer composition and an initiator. Methods can comprise positioning the bioprosthetic heart valve within the anatomical feature of a patient, applying the curable composition to one or both of the bioprosthetic heart valve and the anatomical feature, and curing the curable composition for a cure time. The applying can be performed before or after the positioning.

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