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公开(公告)号:US20240093136A1
公开(公告)日:2024-03-21
申请号:US18520821
申请日:2023-11-28
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher Davidd Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , A01N1/02 , B01L3/00 , B01L9/00 , C12M1/00 , C12M1/34 , C12M1/36 , C12M1/42 , C12M3/00 , C12N5/071
CPC分类号: C12M23/16 , A01N1/021 , A01N1/0247 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/527 , C12M21/08 , C12M23/38 , C12M23/40 , C12M23/42 , C12M29/10 , C12M35/04 , C12M41/40 , C12M41/48 , C12N5/0602 , B01L2200/025 , B01L2200/027 , B01L2200/12 , B01L2300/0681 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/161 , B01L2300/165 , B01L2400/0481 , B01L2400/0487 , B01L2400/06 , C12N2521/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US20190040349A1
公开(公告)日:2019-02-07
申请号:US16152908
申请日:2018-10-05
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , A01N1/02 , C12M1/00 , B01L3/00 , C12M1/34 , C12M3/00 , C12M1/36 , C12M1/42 , C12N5/071
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US11920114B2
公开(公告)日:2024-03-05
申请号:US17176873
申请日:2021-02-16
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , A01N1/02 , B01L3/00 , B01L9/00 , C12M1/00 , C12M1/34 , C12M1/36 , C12M1/42 , C12M3/00 , C12N5/071
CPC分类号: C12M23/16 , A01N1/021 , A01N1/0247 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L9/527 , C12M21/08 , C12M23/38 , C12M23/40 , C12M23/42 , C12M29/10 , C12M35/04 , C12M41/40 , C12M41/48 , C12N5/0602 , B01L2200/025 , B01L2200/027 , B01L2200/12 , B01L2300/0681 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/161 , B01L2300/165 , B01L2400/0481 , B01L2400/0487 , B01L2400/06 , C12N2521/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US20230022203A1
公开(公告)日:2023-01-26
申请号:US17950422
申请日:2022-09-22
申请人: EMULATE, Inc
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , B01L9/00 , C12M1/42 , C12N5/071 , C12M1/34 , A01N1/02 , B01L3/00 , C12M1/00 , C12M3/00 , C12M1/36
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US10184102B2
公开(公告)日:2019-01-22
申请号:US15248748
申请日:2016-08-26
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: G01N1/10 , G01N7/00 , G01N35/08 , G01N35/02 , C12M3/06 , B01L3/00 , C12M1/00 , C12M1/42 , C12M1/34 , C12N5/071 , A01N1/02 , C12M3/00 , C12M1/36
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US20210179992A1
公开(公告)日:2021-06-17
申请号:US17176873
申请日:2021-02-16
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , B01L3/00 , C12M1/00 , C12M1/42 , C12M1/34 , C12N5/071 , A01N1/02 , C12M3/00 , C12M1/36 , B01L9/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US10913924B2
公开(公告)日:2021-02-09
申请号:US16152908
申请日:2018-10-05
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: B01L3/00 , A61J1/06 , C12M3/06 , C12M1/00 , C12M1/42 , C12M1/34 , C12N5/071 , A01N1/02 , C12M3/00 , C12M1/36 , B01L9/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US20190040348A1
公开(公告)日:2019-02-07
申请号:US16152847
申请日:2018-10-05
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , A01N1/02 , C12M1/00 , B01L3/00 , C12M1/34 , C12M3/00 , C12M1/36 , C12M1/42 , C12N5/071
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US11834641B2
公开(公告)日:2023-12-05
申请号:US17950422
申请日:2022-09-22
申请人: EMULATE, Inc
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: C12M3/06 , B01L3/00 , C12M1/00 , C12M1/42 , C12M1/34 , C12N5/071 , A01N1/02 , C12M3/00 , C12M1/36 , B01L9/00
CPC分类号: C12M23/16 , A01N1/021 , A01N1/0247 , B01L3/50273 , B01L3/502707 , B01L3/502715 , B01L3/502738 , B01L9/527 , C12M21/08 , C12M23/38 , C12M23/40 , C12M23/42 , C12M29/10 , C12M35/04 , C12M41/40 , C12M41/48 , C12N5/0602 , B01L2200/025 , B01L2200/027 , B01L2200/12 , B01L2300/0681 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/161 , B01L2300/165 , B01L2400/0481 , B01L2400/0487 , B01L2400/06 , C12N2521/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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公开(公告)号:US10988721B2
公开(公告)日:2021-04-27
申请号:US16152847
申请日:2018-10-05
申请人: EMULATE, Inc.
发明人: Daniel Levner , Josiah Daniel Sliz , Christopher David Hinojosa , Joshua Gomes , Jose Fernandez-Alcon
IPC分类号: G01N1/10 , G01N7/00 , G01N35/08 , G01N35/02 , C12M3/06 , B01L3/00 , C12M1/00 , C12M1/42 , C12M1/34 , C12N5/071 , A01N1/02 , C12M3/00 , C12M1/36 , B01L9/00
摘要: A culture module is contemplated that allows the perfusion and optionally mechanical actuation of one or more microfluidic devices, such as organ-on-a-chip microfluidic devices comprising cells that mimic at least one function of an organ in the body. A method for pressure control is contemplated to allow the control of flow rate (while perfusing cells) despite limitations of common pressure regulators. The method for pressure control allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with said assembly, so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.
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