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公开(公告)号:US11352642B2
公开(公告)日:2022-06-07
申请号:US15542005
申请日:2016-01-07
申请人: Etubics Corporation
IPC分类号: C12N15/63 , C12N15/86 , A61K39/00 , A61K39/235 , C07K16/28 , A61K39/12 , A61K39/395 , A61P31/20 , A61P35/04 , A61P35/00 , A61K45/06 , C07K14/47 , C07K14/705 , C12N7/00
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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公开(公告)号:US11304998B2
公开(公告)日:2022-04-19
申请号:US17240285
申请日:2021-04-26
申请人: ETUBICS CORPORATION
摘要: Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.
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公开(公告)号:US20210260175A1
公开(公告)日:2021-08-26
申请号:US17240285
申请日:2021-04-26
申请人: ETUBICS CORPORATION
摘要: Methods and compositions for generating enhanced immune responses using adenovirus vectors that allow for multiple vaccinations in combination with an IL-15 superagonist complex in subjects in need thereof are provided.
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公开(公告)号:US20190022209A1
公开(公告)日:2019-01-24
申请号:US16070104
申请日:2017-01-13
申请人: ETUBICS CORPORATION
IPC分类号: A61K39/145
摘要: Methods for constructing and producing a recombinant adenovirus based vector vaccine containing multiple influenza antigen genes for use in generating broad based immune responses against influenza A and B viruses and that allows for multiple vaccinations in individuals with preexisting immunity to adenovirus are described. Specifically, the recombinant adenovirus based vector is a replication defective adenovirus vector comprising a deletion in an early 2b (E2b) gene.
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5.
公开(公告)号:US20240226266A1
公开(公告)日:2024-07-11
申请号:US18609152
申请日:2024-03-19
申请人: Etubics Corporation
IPC分类号: A61K39/12 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/00 , A61K39/21 , A61K39/235 , A61P35/00 , C07K14/005 , C07K14/705 , C07K14/71 , C12N15/86
CPC分类号: A61K39/12 , A61K38/191 , A61K38/193 , A61K38/2013 , A61K38/2026 , A61K38/2033 , A61K38/204 , A61K38/2046 , A61K38/2066 , A61K38/208 , A61K38/217 , A61K39/00 , A61K39/0011 , A61K39/001106 , A61K39/001182 , A61K39/21 , A61K39/235 , A61P35/00 , C07K14/005 , C07K14/70503 , C07K14/71 , C12N15/86 , A61K2039/5256 , A61K2039/54 , A61K2039/545 , A61K2039/55555 , A61K2039/57 , A61K2039/575 , C12N2710/10034 , C12N2710/10321 , C12N2710/10334 , C12N2710/10343 , C12N2710/10371 , C12N2710/20034 , C12N2740/15034 , C12N2740/16234 , C12N2800/24
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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6.
公开(公告)号:US20220265809A1
公开(公告)日:2022-08-25
申请号:US17731106
申请日:2022-04-27
申请人: Etubics Corporation
IPC分类号: A61K39/12 , A61K39/21 , C12N15/86 , A61K39/00 , A61P35/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/235 , C07K14/005 , C07K14/705 , C07K14/71
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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公开(公告)号:US11369673B2
公开(公告)日:2022-06-28
申请号:US15265723
申请日:2016-09-14
申请人: Etubics Corporation
IPC分类号: A61K39/12 , A61K39/21 , C12N15/86 , A61K39/00 , A61P35/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/235 , C07K14/005 , C07K14/705 , C07K14/71
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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公开(公告)号:US11149087B2
公开(公告)日:2021-10-19
申请号:US15564413
申请日:2016-04-20
申请人: Etubics Corporation
IPC分类号: C12N15/86 , A61K39/395 , C07K16/28 , C07K16/08 , C07K16/30 , A61K39/29 , A61K39/00 , A61K31/282 , A61K31/513 , A61K31/519 , A61K38/17 , A61K39/12
摘要: Methods and compositions for generating immune responses using adenovirus vectors that allow multiple vaccinations or in combination with other therapy and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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9.
公开(公告)号:US20230364218A1
公开(公告)日:2023-11-16
申请号:US18361084
申请日:2023-07-28
申请人: Etubics Corporation
IPC分类号: A61K39/12 , A61K39/21 , C12N15/86 , A61K39/00 , A61P35/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/235 , C07K14/005 , C07K14/705 , C07K14/71
CPC分类号: A61K39/12 , A61K39/21 , C12N15/86 , A61K39/00 , A61P35/00 , A61K39/001106 , A61K39/001182 , A61K38/191 , A61K38/193 , A61K38/2013 , A61K38/2026 , A61K38/2033 , A61K38/204 , A61K38/2046 , A61K38/2066 , A61K38/208 , A61K38/217 , A61K39/235 , A61K39/0011 , C07K14/005 , C07K14/70503 , C07K14/71 , A61K2039/5256 , C12N2710/10343 , A61K2039/545 , C12N2740/16234 , C12N2710/10334 , C12N2710/10034 , A61K2039/54 , A61K2039/55555 , A61K2039/575 , C12N2710/10321 , C12N2710/20034 , C12N2740/15034 , C12N2800/24 , A61K2039/57 , C12N2710/10371
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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10.
公开(公告)号:US20230070595A1
公开(公告)日:2023-03-09
申请号:US17986424
申请日:2022-11-14
申请人: Etubics Corporation
IPC分类号: A61K39/12 , A61K39/21 , C12N15/86 , A61K39/00 , A61P35/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/235 , C07K14/005 , C07K14/705 , C07K14/71
摘要: Methods for generating immune responses using adenovirus vectors that allow multiple vaccinations with the same adenovirus vector and vaccinations in individuals with preexisting immunity to adenovirus are provided.
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