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公开(公告)号：US20090246201A1
公开(公告)日：2009-10-01
申请号：US11893095
申请日：2007-08-14
申请人： Edward Alexander McKenzie , Alasdair Craig Stamps , Jonathan Alexander Terrett , Kerry Louise Tyson
发明人： Edward Alexander McKenzie , Alasdair Craig Stamps , Jonathan Alexander Terrett , Kerry Louise Tyson
IPC分类号： A61K39/395 , C12N9/10 , C07K16/18 , C12N15/11 , C12N15/00 , C12N5/06 , C12P21/02 , A61K38/45 , C12Q1/48
CPC分类号： C12Y302/01166 , C12N9/2402
摘要： The present invention provides a homologue to heparanase which is present in three splice variants.
摘要翻译： 本发明提供了存在于三个剪接变体中的乙酰肝素酶的同源物。
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公开(公告)号：US07273744B2
公开(公告)日：2007-09-25
申请号：US10177245
申请日：2002-06-21
申请人： Edward Alexander McKenzie , Alasdair Craig Stamps , Jonathan Alexander Terrett , Kerry Louise Tyson
发明人： Edward Alexander McKenzie , Alasdair Craig Stamps , Jonathan Alexander Terrett , Kerry Louise Tyson
CPC分类号： C12Y302/01166 , C12N9/2402
摘要： The present invention provides a homologue to heparanase which is present in three splice variants.
摘要翻译： 本发明提供了存在于三个剪接变体中的乙酰肝素酶的同源物。
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公开(公告)号：US20100015152A1
公开(公告)日：2010-01-21
申请号：US12386354
申请日：2009-04-16
IPC分类号： A61K39/395 , G01N33/574 , A61K38/17 , C12Q1/68 , A61K31/711 , G01N33/566 , A61P35/00
CPC分类号： A61K49/0002 , A61K39/00 , A61K47/42 , A61K48/00 , A61K51/1051 , A61K2039/505 , A61K2039/53 , C07K14/47 , C07K2319/00 , C12Q1/6886 , C12Q2600/112 , C12Q2600/136 , C12Q2600/158 , G01N33/57407 , G01N33/57415 , G01N33/57419 , G01N33/57434 , G01N33/57438 , G01N2500/00
摘要： The present invention provides the use of a protein found in breast, prostate, pancreatic and colon cancer cell membranes, known as BCMP 7, in the diagnosis, screening, treatment and prophylaxis of breast, prostate, pancreatic and/or colon cancer, as well as compositions comprising BCMP 7, including vaccines and antibodies that are immunospecific for BCMP 7.
摘要翻译： 本发明提供在乳腺癌，前列腺癌，胰腺癌和结肠癌细胞膜中发现的蛋白质，被称为BCMP 7的蛋白质在诊断，筛选，治疗和预防乳腺癌，前列腺癌，胰腺癌和/或结肠癌中的用途，以及 作为包含BCMP 7的组合物，包括针对BCMP 7免疫特异性的疫苗和抗体。
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公开(公告)号：US20090214540A1
公开(公告)日：2009-08-27
申请号：US11920029
申请日：2006-05-16
IPC分类号： A61K39/395 , A61K39/00 , G01N33/566 , G01N33/68 , G01N33/53
CPC分类号： G01N33/57484 , A61K38/1709 , A61K39/395 , G01N2500/00 , G01N2800/52
摘要： The present invention relates to new uses of PSK-1 in the diagnosis, screening, treatment and prophylaxis of ovarian and lung cancer. The invention also provides compositions comprising PSK-1, including vaccines, antibodies that are immunospecific for PSK-1 and agents which interact with or modulate the expression or activity of PSK-1 or which modulate the expression of the nucleic acid which codes for PSK-1.
摘要翻译： 本发明涉及PSK-1在诊断，筛选，治疗和预防卵巢癌和肺癌中的新用途。 本发明还提供包含PSK-1的组合物，包括疫苗，对PSK-1具有免疫特异性的抗体和与PSK-1的表达或活性相互作用或调节PSK-1的表达或活性或调节编码PSK- 1。
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