-
1.发明申请TOOL RADIUS ADJUSTING SYSTEM FOR BORING HOLDER, TOOL RADIUS ADJUSTING METHOD IN MACHINE TOOL, AND MACHINE TOOL 有权工具用于镗床的工具半径调节系统，机床工具的半径调整方法和机床公开(公告)号：US20110116880A1
公开(公告)日：2011-05-19
申请号：US12942433
申请日：2010-11-09
IPC分类号： B23B29/034 , B23B49/00 , B23B47/18
CPC分类号： B23Q17/2457 , B23B29/03421 , B23B29/03425 , B23B2250/04 , B23B2260/092 , B23B2270/025 , B23B2270/027 , B23B2270/48 , Y10T29/5105 , Y10T82/10 , Y10T408/03 , Y10T408/08 , Y10T408/175 , Y10T408/85 , Y10T408/858
摘要： A boring holder in a tool radius adjusting system is provided with a cutting blade and fine and coarse motion adjusting mechanisms each capable of adjusting the position of the cutting blade relative to a rotational axis of the boring holder. The tool radius adjusting system is provided with a tool radius measuring device for measuring the tool radius of the boring holder and a controller configured to calculate a compensation amount based on a tool radius measured by the tool radius measuring device and a target tool radius and to operate the fine and coarse motion adjusting mechanisms based on the compensation amount so that the tool radius is brought into agreement with the target tool radius.
摘要翻译： 刀具半径调节系统中的钻头支架设置有切割刀片和精细和粗略的运动调节机构，每个机构能够调节切割刀片相对于镗刀架的旋转轴线的位置。 刀具半径调节系统设置有用于测量镗刀架的刀具半径的刀具半径测量装置和配置为基于由刀具半径测量装置测量的刀具半径和目标刀具半径来计算补偿量的控制器，并且 基于补偿量运行精细和粗调运动调节机构，使刀具半径与目标刀具半径一致。
-
2.发明授权Tool radius adjusting method in machine tool and machine tool for practicing the method 有权用于实施该方法的机床和机床中的刀具半径调整方法公开(公告)号：US09033623B2
公开(公告)日：2015-05-19
申请号：US13509911
申请日：2010-11-10
申请人： Eiji Nakamura , Akihiko Kadota , Takashi Yokoyama , Yasuhiro Komai , Harumi Sawaki , Shun Sawaki , Aya Sawaki , Taku Sawaki
IPC分类号： B23B29/034 , B23B35/00
CPC分类号： B23B29/03403 , B23B29/03421 , B23B29/03425 , B23B29/03489 , B23B35/00 , B23B2250/04 , B23B2270/025 , B23B2270/027 , B23B2270/48 , Y10T82/10 , Y10T408/03 , Y10T408/175 , Y10T408/85 , Y10T408/858
摘要： At a contact step in a tool radius adjusting method, a reference portion of a movable body provided radially movably on a housing of a boring tool and a position adjusting reference member fixed on a machine tool are brought into contact by sliding the movable body relative to the housing so that the position of a cutting blade comes to a predetermined position in a direction to go away from a rotational axis. Then, at an adjusting step, the position of the cutting blade relative to the rotational axis is adjusted by changing the relative position between a tool spindle holding the boring tool and the position adjusting reference member in a direction to come close to each other by drive mechanisms of the machine tool used for positioning a spindle head with the tool spindle relative to a workpiece in machining the workpiece with the cutting blade.
摘要翻译： 在工具半径调整方法的接触步骤中，通过使可移动体相对于所述移动体相对于所述可移动体相对于所述移动体相对于所述移动体相对于所述移动体相对于所述移动体 所述壳体使得切割刀片的位置在远离旋转轴线的方向上到达预定位置。 然后，在调整步骤中，通过在保持钻孔工具的工具主轴与位置调整基准构件之间的相对位置通过驱动方向彼此靠近的方向来改变切割刀片相对于旋转轴线的位置 机床用于在与切割刀片一起加工工件时，将主轴头与工具主轴相对于工件定位。
-
3.发明申请TOOL RADIUS ADJUSTING METHOD IN MACHINE TOOL AND MACHINE TOOL FOR PRACTICING THE METHOD 有权用于实施方法的机床工具和机床的工具半径调整方法公开(公告)号：US20130064616A1
公开(公告)日：2013-03-14
申请号：US13509911
申请日：2010-11-10
申请人： Eiji Nakamura , Akihiko Kadota , Takashi Yokoyama , Yasuhiro Komai , Harumi Sawaki , Shun Sawaki , Aya Sawaki , Taku Sawaki
CPC分类号： B23B29/03403 , B23B29/03421 , B23B29/03425 , B23B29/03489 , B23B35/00 , B23B2250/04 , B23B2270/025 , B23B2270/027 , B23B2270/48 , Y10T82/10 , Y10T408/03 , Y10T408/175 , Y10T408/85 , Y10T408/858
摘要： At a contact step in a tool radius adjusting method, a reference portion of a movable body provided radially movably on a housing of a boring tool and a position adjusting reference member fixed on a machine tool are brought into contact by sliding the movable body relative to the housing so that the position of a cutting blade comes to a predetermined position in a direction to go away from a rotational axis. Then, at an adjusting step, the position of the cutting blade relative to the rotational axis is adjusted by changing the relative position between a tool spindle holding the boring tool and the position adjusting reference member in a direction to come close to each other by drive mechanisms of the machine tool used for positioning a spindle head with the tool spindle relative to a workpiece in machining the workpiece with the cutting blade.
摘要翻译： 在工具半径调整方法的接触步骤中，通过使可移动体相对于所述移动体相对于所述可移动体相对于所述移动体相对于所述移动体相对于所述移动体相对于所述移动体 所述壳体使得切割刀片的位置在远离旋转轴线的方向上到达预定位置。 然后，在调整步骤中，通过在保持钻孔工具的工具主轴与位置调整基准构件之间的相对位置通过驱动方向彼此靠近的方向来改变切割刀片相对于旋转轴线的位置 机床用于在与切割刀片一起加工工件时，将主轴头与工具主轴相对于工件定位。
-
公开(公告)号：US20120058871A1
公开(公告)日：2012-03-08
申请号：US13217555
申请日：2011-08-25
申请人： Eiji NAKAMURA , Akihiko Kadota , Takashi Yokoyama
发明人： Eiji NAKAMURA , Akihiko Kadota , Takashi Yokoyama
IPC分类号： B23Q3/157
CPC分类号： B23Q3/15713 , B23B29/03421 , B23B29/03425 , B23B29/03432 , B23Q3/1574 , Y10T408/76 , Y10T408/856 , Y10T408/85843 , Y10T483/12 , Y10T483/13 , Y10T483/15 , Y10T483/1738
摘要： A tool radius adjusting device executes an operation for adjusting the tool radius of a boring holder in parallel with execution of a machining program for executing an operation of a spindle head and an operation of a tool changer. A carrier control unit determines whether the tool changer is executing a tool changing process. When the tool changing process is not being executed, the carrier control unit allows the carrier device to execute an operation for picking the boring holder out from the tool magazine and an operation for returning the boring holder, of which the tool radius has been adjusted, to the tool magazine.
摘要翻译： 刀具半径调节装置执行与执行用于执行主轴头的操作的加工程序和刀具更换器的操作并行地调整镗刀架的刀具半径的操作。 载体控制单元确定换刀器是否正在执行换刀过程。 当不执行换刀过程时，承运人控制单元允许承运人装置执行从工具仓中取出镗刀架的操作和用于使已经调整了刀具半径的镗刀架返回的操作， 到工具杂志。
-
公开(公告)号：US08998785B2
公开(公告)日：2015-04-07
申请号：US13217555
申请日：2011-08-25
申请人： Eiji Nakamura , Akihiko Kadota , Takashi Yokoyama
发明人： Eiji Nakamura , Akihiko Kadota , Takashi Yokoyama
IPC分类号： B23Q3/157 , B23B29/034
CPC分类号： B23Q3/15713 , B23B29/03421 , B23B29/03425 , B23B29/03432 , B23Q3/1574 , Y10T408/76 , Y10T408/856 , Y10T408/85843 , Y10T483/12 , Y10T483/13 , Y10T483/15 , Y10T483/1738
摘要： A tool radius adjusting device executes an operation for adjusting the tool radius of a boring holder in parallel with execution of a machining program for executing an operation of a spindle head and an operation of a tool changer. A carrier control unit determines whether the tool changer is executing a tool changing process. When the tool changing process is not being executed, the carrier control unit allows the carrier device to execute an operation for picking the boring holder out from the tool magazine and an operation for returning the boring holder, of which the tool radius has been adjusted, to the tool magazine.
摘要翻译： 刀具半径调节装置执行与执行用于执行主轴头的操作的加工程序和刀具更换器的操作并行地调整镗刀架的刀具半径的操作。 载体控制单元确定换刀器是否正在执行换刀过程。 当不执行换刀过程时，承运人控制单元允许承运人装置执行从工具仓中取出镗刀架的操作和用于使已经调整了刀具半径的镗刀架返回的操作， 到工具杂志。
-
6.发明授权Tool radius adjusting system for boring holder, tool radius adjusting method in machine tool, and machine tool 有权镗刀刀具半径调节系统，机床刀具半径调整方式，机床公开(公告)号：US08881354B2
公开(公告)日：2014-11-11
申请号：US12942433
申请日：2010-11-09
IPC分类号： B23B29/034
CPC分类号： B23Q17/2457 , B23B29/03421 , B23B29/03425 , B23B2250/04 , B23B2260/092 , B23B2270/025 , B23B2270/027 , B23B2270/48 , Y10T29/5105 , Y10T82/10 , Y10T408/03 , Y10T408/08 , Y10T408/175 , Y10T408/85 , Y10T408/858
摘要： A boring holder in a tool radius adjusting system is provided with a cutting blade and fine and coarse motion adjusting mechanisms each capable of adjusting the position of the cutting blade relative to a rotational axis of the boring holder. The tool radius adjusting system is provided with a tool radius measuring device for measuring the tool radius of the boring holder and a controller configured to calculate a compensation amount based on a tool radius measured by the tool radius measuring device and a target tool radius and to operate the fine and coarse motion adjusting mechanisms based on the compensation amount so that the tool radius is brought into agreement with the target tool radius.
摘要翻译： 刀具半径调节系统中的钻头支架设置有切割刀片和精细和粗略的运动调节机构，每个机构能够调节切割刀片相对于镗刀架的旋转轴线的位置。 刀具半径调节系统设置有用于测量镗刀架的刀具半径的刀具半径测量装置和配置为基于由刀具半径测量装置测量的刀具半径和目标刀具半径来计算补偿量的控制器，并且 基于补偿量运行精细和粗调运动调节机构，使刀具半径与目标刀具半径一致。
-
7.发明授权Methods for producing human lymphocytes and human monoclonal antibodies, and human monoclonal antibodies produced thereby 失效用于产生人淋巴细胞和人单克隆抗体的方法以及由此产生的人单克隆抗体
公开(公告)号：US5681729A
公开(公告)日：1997-10-28
申请号：US969336
申请日：1992-10-30
IPC分类号： A01K67/027 , A61K38/00 , C07K16/00 , C07K16/18 , C07K16/30 , C12N5/08 , C12N5/28 , C12N15/85 , C12P21/08 , G01N33/574 , C12N15/07
CPC分类号： A01K67/0271 , C07K16/00 , C07K16/18 , C07K16/30 , C12N15/8509 , A01K2217/05 , A01K2227/105 , A01K2267/01 , A01K2267/0381 , A61K38/00 , C07K2317/21
摘要： A method for isolating a human lymphocyte producing an antibody specific to a desired antigen, a method for isolating a monoclonal antibody, as well as monoclonal antibodies produced by the method, are described. The present invention provides a method for isolating a human lymphocyte producing an antibody comprising, in the order mentioned, the steps of: transplanting human lymphocytes into an immunodeficient animal so that the human lymphocytes take in the animal body; immunizing the animal with a desired antigen so as to generate human lymphocytes producing an antibody specific to the antigen; recovering lymphocytes producing antibody by incubating with anti-mouse antibody; and separating human lymphocytes from mouse by centrifugation. The present invention also provides a method for producing a monoclonal antibody comprising, in the order mentioned, the steps of: immortalizing the human lymphocytes producing the antibody which were obtained by the above-mentioned method of the present invention; cloning the obtained immortalized human-derived lymphocytes producing the antibody; and recovering a monoclonal antibody specific to the desired antigen from the cloned immortalized human-derived lymphocytes.
摘要翻译： 描述了分离产生对所需抗原特异性抗体的人淋巴细胞的方法，分离单克隆抗体的方法以及通过该方法产生的单克隆抗体。 本发明提供一种用于分离产生抗体的人淋巴细胞的方法，其包括以下步骤：将人淋巴细胞移植到免疫缺陷型动物中，使得人淋巴细胞摄入动物体内; 用所需抗原免疫动物，以产生产生抗原特异性抗体的人淋巴细胞; 通过与抗小鼠抗体孵育来回收产生抗体的淋巴细胞; 并通过离心从小鼠分离人淋巴细胞。 本发明还提供一种单克隆抗体的制备方法，其特征在于，按照上述顺序，通过上述本发明方法获得的产生抗体的人淋巴细胞的永生化步骤; 克隆获得的产生抗体的永生化的人源性淋巴细胞; 并从克隆的永生化人源性淋巴细胞中回收对所需抗原特异性的单克隆抗体。
-
8.发明授权Methods for producing human lymphocytes and human monoclonal antibodies, and human monoclonal antibodies produced thereby 失效用于产生人淋巴细胞和人单克隆抗体的方法以及由此产生的人单克隆抗体
公开(公告)号：US5869268A
公开(公告)日：1999-02-09
申请号：US815953
申请日：1997-03-13
IPC分类号： A01K67/027 , A61K38/00 , C07K16/00 , C07K16/18 , C07K16/30 , C12N5/08 , C12N5/28 , C12N15/85 , C12P21/08 , G01N33/574
CPC分类号： A01K67/0271 , C07K16/00 , C07K16/18 , C07K16/30 , C12N15/8509 , A01K2217/05 , A01K2227/105 , A01K2267/01 , A01K2267/0381 , A61K38/00 , C07K2317/21
摘要： A method for producing a human lymphocyte producing an antibody specific to a desired antigen, a method for producing a monoclonal antibody, as well as monoclonal antibodies produced by the method, are described. The present invention provides a method for producing a human lymphocyte producing an antibody comprising, in the order mentioned, the steps of: transplanting human lymphocytes into an immunodeficient animal so that the human lymphocytes take in the animal body; immunizing the animal with a desired antigen so as to generate human lymphocytes producing an antibody specific to the antigen; and recovering the human lymphocytes producing the antibody from the animal. The present invention also provides a method for producing a monoclonal antibody comprising, in the order mentioned, the steps of: immortalizing the human lymphocytes producing the antibody which were obtained by the above-mentioned method of the present invention; cloning the obtained immortalized human-derived lymphocytes producing the antibody; and recovering a monoclonal antibody specific to the desired antigen from the cloned immortalized human-derived lymphocytes.
摘要翻译： 对生产对所需抗原特异性抗体的人淋巴细胞的制造方法，单克隆抗体的制造方法以及由该方法制造的单克隆抗体进行说明。 本发明提供了产生抗体的人淋巴细胞的制备方法，其特征在于，按照以下顺序，将人淋巴细胞移植到免疫缺陷型动物中，使人体淋巴细胞摄入动物体内; 用所需抗原免疫动物，以产生产生抗原特异性抗体的人淋巴细胞; 以及从动物中回收产生抗体的人淋巴细胞。 本发明还提供一种单克隆抗体的制备方法，其特征在于，按照上述顺序，通过上述本发明方法获得的产生抗体的人淋巴细胞的永生化步骤; 克隆获得的产生抗体的永生化的人源性淋巴细胞; 并从克隆的永生化人源性淋巴细胞中回收对所需抗原特异性的单克隆抗体。
-
公开(公告)号：US6010903A
公开(公告)日：2000-01-04
申请号：US418385
申请日：1995-04-07
申请人： Shuichi Hiyamuta , Keiko Shimizu , Akihiko Kadota
发明人： Shuichi Hiyamuta , Keiko Shimizu , Akihiko Kadota
CPC分类号： C07K16/38 , Y10S436/811
摘要： Disclosed is a monoclonal antibody which specifically reacts with active human ceruloplasmin as well as a method for diagnosing Wilson's disease using the same. The monoclonal antibody of the present invention specifically reacts with active human ceruloplasmin, it neutralizes the peroxidase activity of the active human ceruloplasmin upon binding thereto, and it does not specifically react with inactive human ceruloplasmin.
摘要翻译： 公开了与活性人血浆铜蓝蛋白特异性反应的单克隆抗体以及使用其进行威尔逊氏病诊断的方法。 本发明的单克隆抗体与活性人血浆铜蓝蛋白特异性地反应，其结合时中和活性人血浆铜蓝蛋白的过氧化物酶活性，并且不与无活性人血浆铜蓝蛋白特异性反应。
-
公开(公告)号：US20090155417A1
公开(公告)日：2009-06-18
申请号：US12067050
申请日：2006-08-01
申请人： Akihiko Kadota , Motoshi Suzuki , Kuniko Suzuki , Shinji Ito , Yasuaki Sugimoto , Masami Mochizuki
发明人： Akihiko Kadota , Motoshi Suzuki , Kuniko Suzuki , Shinji Ito , Yasuaki Sugimoto , Masami Mochizuki
CPC分类号： A61K36/06 , A23K10/18 , A23K20/189 , A23K50/10 , A23K50/30 , A23K50/60 , A23K50/75 , A61K36/062 , A61K2300/00
摘要： To promote the digestion of an animal to thereby elevate the feed efficiency or prevent or ameliorate intestinal infections such as inflammatory intestinal injury of the animal, a combination of at least one fungus selected from Aspergillus sojae, Aspergillus tamarii, Aspergillus foetidus, Aspergillus niger, and Aspergillus oryzae with an acidic enzyme produced by the fungus is administered to the animal.
摘要翻译： 为了促进动物的消化，从而提高饲料效率或预防或改善肠道感染如动物的炎性肠损伤，选择至少一种选自曲霉菌，曲霉菌，曲霉菌，黑曲霉和 将由真菌产生的酸性酶的米曲霉施用于动物。
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.021 秒)
