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15 条记录 (耗时 0.028 秒)

    PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DISEASE RESULTING FROM ABNORMAL BONE METABOLISM
    1.
    发明申请
    PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DISEASE RESULTING FROM ABNORMAL BONE METABOLISM 审中-公开
    异丙酚代谢异常的治疗药物或治疗药物

    公开(公告)号：US20110306580A1

    公开(公告)日：2011-12-15

    申请号：US13147133

    申请日：2010-01-29

    申请人： Eiji Ochiai ,  Yasunori Nakayama ,  Jin-Soo Lee ,  Yun-Ha Hwang ,  Doc-Gyun Jeong

    发明人： Eiji Ochiai ,  Yasunori Nakayama ,  Jin-Soo Lee ,  Yun-Ha Hwang ,  Doc-Gyun Jeong

    IPC分类号： A61K31/59 ,  A61P19/08 ,  A61P19/10 ,  A61K31/593

    CPC分类号： A61K31/426 ,  A61K31/593

    摘要： The object of the present invention is to provide a therapeutic agent or a prophylactic agent for a disease resulting from an abnormal bone metabolism, especially osteoporosis which is more effective than conventional agents. Excellent therapeutic effect or prophylactic effect on a disease resulting from an abnormal bone metabolism, especially osteoporosis, compared with the effect in administration of each compound alone can be obtained by the combination of an N-hydroxybenzamidine derivative represented by Formula (I) or a salt thereof with an activated vitamin D or a prodrug thereof.

    摘要翻译： 本发明的目的是提供一种由异常骨代谢引起的疾病，特别是比常规药物更有效的骨质疏松症的治疗剂或预防剂。 通过将式（I）表示的N-羟基苄脒衍生物或盐的盐组合，可以获得与单独施用化合物的效果相比，由于骨代谢异常，特别是骨质疏松引起的疾病的优异的治疗效果或预防效果 其具有活化的维生素D或其前药。

    Image forming process and apparatus and control method thereof
    7.
    发明授权
    Image forming process and apparatus and control method thereof 有权

    公开(公告)号：US06512909B2

    公开(公告)日：2003-01-28

    申请号：US09922003

    申请日：2001-07-31

    申请人： Yoshio Ozawa ,  Eiji Ochiai ,  Shoichi Sakata

    发明人： Yoshio Ozawa ,  Eiji Ochiai ,  Shoichi Sakata

    IPC分类号： G03G1509

    CPC分类号： G03G13/08 ,  G03G15/065 ,  G03G2215/0607 ,  G03G2215/0634

    摘要： When image formation is performed by an apparatus comprising: a magnetic roll for generating a magnetic brush by carrier having toner adhering triboelectrically thereto, a developer roll on the surface of which a thin layer of the toner supplied by the magnetic brush is formed, and a photoreceptor onto which the toner of thin layer jumps selectively in accordance with the latent image thereon; positively chargeable toner of which charge amount is controlled in 5˜20 &mgr;C/g is used, the surface potential of the photoreceptor is set to a range above 0 to 250 V, and the after exposure potential which is the potential right after the photoreceptor is exposed is in a range of 0˜ to 100 V.

    Process for producing image and two-component developer
    8.
    发明授权
    Process for producing image and two-component developer 失效
    生产图像和双组分显影剂的方法

    公开(公告)号：US5824445A

    公开(公告)日：1998-10-20

    申请号：US855789

    申请日：1997-05-12

    申请人： Eiji Ochiai ,  Makoto Hamaguchi ,  Hiroyoshi Tode

    发明人： Eiji Ochiai ,  Makoto Hamaguchi ,  Hiroyoshi Tode

    IPC分类号： G03G9/08 ,  G03G5/08 ,  G03G5/082 ,  G03G9/10 ,  G03G9/107 ,  G03G9/113 ,  G03G9/083

    CPC分类号： G03G5/08221 ,  G03G9/107 ,  G03G9/113

    摘要： A process for producing an image comprising the steps of: electrically charging a photoreceptor under dark; forming a latent image on the photoreceptor through selective imagewise exposure to light; and developing the latent image with a two-component developer comprising a carrier and a toner, the photoreceptor comprising a conductive substrate having thereon a photoconductive layer comprising amorphous silicon having a thickness of 25 .mu.m or less, the carrier is a magnetic material carrier comprising particles of a magnetic material having an average particle diameter of from 35 to 60 .mu.m, where the content of particles having a diameter of 44 .mu.m or more is 35% by weight or more. A two-component developer comprising a carrier and a toner, the carrier comprising particles of a magnetic material having an average particle diameter of from 35 to 60 .mu.m, where the content of particles having a diameter of 44 .mu.m or more is 35% by weight or more.

    摘要翻译： 一种用于产生图像的方法，包括以下步骤：在黑暗下对感光体进行充电; 通过选择性地成像曝光在感光体上形成潜像; 并使用包含载体和调色剂的双组分显影剂显影潜像，所述感光体包括其上具有厚度为25μm或更小的非晶硅的光电导层的导电基底，所述载体是包含 具有平均粒径为35〜60μm的磁性材料的粒子，其中直径为44μm以上的粒子的含量为35重量％以上。 包含载体和调色剂的双组分显影剂，载体包含平均粒径为35至60μm的磁性材料颗粒，其中直径为44μm或更大的颗粒的含量为35％ 重量以上。

    Image forming process and an image forming apparatus
    9.
    发明授权
    Image forming process and an image forming apparatus 有权
    图像形成处理和图像形成装置

    公开(公告)号：US06324354B1

    公开(公告)日：2001-11-27

    申请号：US09507880

    申请日：2000-02-22

    申请人： Hiroyoshi Tode ,  Masayoshi Yamada ,  Eiji Ochiai

    发明人： Hiroyoshi Tode ,  Masayoshi Yamada ,  Eiji Ochiai

    IPC分类号： G03G1508

    CPC分类号： G03G15/0806

    摘要： The present invention relates to an image forming process and an image forming apparatus, which have a refresh means which refreshes the developing sleeve by allowing the toner on the developing sleeve to jump toward the photoreceptor drum when transfer to recording medium is not done. Refresh is performed by applying an AC bias between the photoreceptor drum and the developing sleeve. The number of dots of latent image corresponding to actual image pattern is counted and the ratio of this number of dots to the number of dots corresponding to full black original image is defined as print rate, and cumulative average print rate is calculated each time when a page or a predetermined number of pages is printed. When the average print rate falls short of proper print rate, refresh is performed. It is suitable to set several proper print rate, and the duration of application of the AC bias is varied according to the average print rate. It is also effective to apply AC bias for refresh higher in effective voltage than applied for developing. It is also effective to prevent “fog” by applying transfer reverse bias to transfer part until the toner on the photoreceptor passes the transfer part and transfer positive bias after cleaning of the toner on the photoreceptor is finished. Generally, when an image forming apparatus is used for an extended period of time or when low print rate original image is copied in large quantity, deterioration such as reduction in print density and “fog” is liable to occur. According to the present invention, even if images of low print rate is copied in large quantity, deterioration does not occur.

    摘要翻译： 本发明涉及一种图像形成处理和图像形成装置，其具有刷新装置，该刷新装置通过使未显影转印到记录介质上的显影套筒上的调色剂向着感光鼓跳转而刷新显影套筒。刷新是 通过在感光鼓和显影套筒之间施加AC偏压来执行。对与实际图像图案相对应的潜像的点数进行计数，并且定义该点数与对应于全黑色原始图像的点数的比率 作为打印率，并且每当打印页面或预定页数时计算累积平均打印速率。当平均打印速率低于正确的打印速率时，执行刷新。 适合设定几种正确的打印速度，AC偏置的使用持续时间根据平均打印速度而变化。在施加有效电压的AC偏压上应用交流偏压也适用于显影。它也是有效的 通过将转印反转偏压施加到转印部件直到感光体上的调色剂通过转印部分并且在清洁感光体上的调色剂之后传递正偏压才能有效地防止“雾”。通常，当图像形成装置用于 延长的时间段或者当大量拷贝低打印率的原始图像时，易于发生诸如打印浓度降低和“雾”的劣化。根据本发明，即使打印率低的图像被大量地复印 数量，不发生变质。