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    Detection of chronic fatigue syndrome
    2.
    发明授权
    Detection of chronic fatigue syndrome 失效
    慢性疲劳综合征检测

    公开(公告)号：US5830668A

    公开(公告)日：1998-11-03

    申请号：US766677

    申请日：1996-12-13

    申请人： Eli Mordechai ,  Aristo Vojdani

    发明人： Eli Mordechai ,  Aristo Vojdani

    IPC分类号： C12Q1/48 ,  C12Q1/68 ,  G01N1/30 ,  G01N33/50 ,  G01N33/573 ,  G01N33/53

    CPC分类号： G01N33/573 ,  C12Q1/48 ,  G01N1/30 ,  G01N33/5091

    摘要： A method for diagnosing chronic fatigue syndrome in an individual. Peripheral blood monocytes are isolated and p68 kinase activity, mRNA levels, protein levels, apoptosis and cell cycle analysis are measured. Significantly increased levels of any of these compared to healthy control individuals indicates the presence of chronic fatigue syndrome.

    摘要翻译： 一种诊断个体慢性疲劳综合征的方法。 分离外周血单核细胞，测定p68激酶活性，mRNA水平，蛋白水平，细胞凋亡和细胞周期分析。 与健康对照个体相比，任何这些相比显着增加，表明存在慢性疲劳综合征。

    Methods and compositions related thereto for detecting and identifying distinct species of nucleic acids from causative agents
    5.
    发明授权
    Methods and compositions related thereto for detecting and identifying distinct species of nucleic acids from causative agents 有权
    与之相关的方法和组合物用于检测和鉴定来自致病因子的不同种类的核酸

    公开(公告)号：US08932832B2

    公开(公告)日：2015-01-13

    申请号：US13199380

    申请日：2011-08-26

    申请人： Martin E. Adelson ,  Melanie Feola ,  Jason Trama ,  Eli Mordechai

    发明人： Martin E. Adelson ,  Melanie Feola ,  Jason Trama ,  Eli Mordechai

    IPC分类号： C07H21/04 ,  C12Q1/70

    CPC分类号： C12Q1/705

    摘要： Methods are described herein for detecting and identifying distinct species of nucleic acids, in a single container, for example, from a certain genus of infectious agents or otherwise causative agents comprising, for example, providing a forward PCR primer common to a homologous gene region between the distinct species, and providing a reverse PCR primer common to a homologous gene region between the distinct species, to thereby define a PCR target region amongst the species, and providing a first oligonucleotide probe specific to a nucleic acid sequence within the target region that is characteristic of a first species, providing a second oligonucleotide probe specific to a nucleic acid sequence within the target region that is characteristic of a second species, wherein the first and second oligonucleotide probes are each detectably labeled with distinctly different detectable labels, conducting a PCR reaction in the container by means of the primers to amplify the target region amongst the species, and detecting the distinct labels, thereby identifying distinct species of nucleic acids corresponding to distinct species of infectious agents. Methods are preferred, for example, wherein the infectious agent is a member of the Herpesviridae family.

    摘要翻译： 在本文中描述了用于在单个容器中，例如来自某一感染因子或其他致病因子的单个容器中检测和鉴定不同种类的核酸的方法，所述诱导剂包括例如提供在同源基因区域之间共同的正向PCR引物 并且提供与不同物种之间的同源基因区域共有的反向PCR引物，从而在物种间限定PCR靶区域，并提供对靶区域内的核酸序列特异的第一寡核苷酸探针， 提供对目标区域内具有特征的第二种类的核酸序列特异性的第二寡核苷酸探针，其中第一和第二寡核苷酸探针各自可检测地用明显不同的可检测标记物标记，进行PCR反应 在容器中通过引物扩增目标区域amo 并检测不同的标签，从而识别与不同种类的感染因子相对应的不同种类的核酸。 方法是优选的，例如，其中感染剂是疱疹病毒科家族的成员。

    RESPONDING TO NATURAL LANGUAGE QUERIES
    7.
    发明申请
    RESPONDING TO NATURAL LANGUAGE QUERIES 有权
    对自然语言查询

    公开(公告)号：US20140095145A1

    公开(公告)日：2014-04-03

    申请号：US13629885

    申请日：2012-09-28

    申请人： Ohad Assulin ,  Ira Cohen ,  Eli Mordechai ,  Boaz Shor ,  Alon Sade

    发明人： Ohad Assulin ,  Ira Cohen ,  Eli Mordechai ,  Boaz Shor ,  Alon Sade

    IPC分类号： G06F17/28

    CPC分类号： G06F17/28 ,  G06F17/30401

    摘要： Disclosed herein are a system, non-transitory computer-readable medium, and method for responding to natural language queries. Keywords likely to appear in a natural language query are determined and each likely keyword is associated with a module. A response to a natural language query comprises information generated by each module associated with a likely keyword appearing in the natural language query.

    摘要翻译： 本文公开了一种用于响应自然语言查询的系统，非暂时性计算机可读介质和方法。 确定可能出现在自然语言查询中的关键字，并且每个可能的关键字与模块相关联。 对自然语言查询的响应包括由与自然语言查询中出现的可能关键字相关联的每个模块生成的信息。

    Matching a user to a conversation
    8.
    发明授权
    Matching a user to a conversation 有权
    将用户与会话相匹配

    公开(公告)号：US08504585B2

    公开(公告)日：2013-08-06

    申请号：US13149869

    申请日：2011-05-31

    申请人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai

    发明人： Ira Cohen ,  Michal Aharon ,  Eli Mordechai

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30699 ,  G06Q10/103

    摘要： A method for matching a user to a conversation includes, for each of a plurality of documents, mapping the document to one or more of a plurality of topics. The document is associated with a user. For each user, the user is mapped to each of the plurality of topics that are mapped to documents with which the user is associated. One of the users is matched to a conversation according to the mappings of the users to those of the plurality of topics that are also mapped to the conversation.

    摘要翻译： 用于将用户与对话相匹配的方法包括针对多个文档中的每一个将所述文档映射到多个主题中的一个或多个。 该文档与用户相关联。 对于每个用户，用户被映射到映射到用户与之关联的文档的多个主题中的每一个。 其中一个用户根据用户的映射与被映射到对话的多个主题的映射进行对话。

    Method of determining types I, II, III, IV or V or methicillin-resistant staphylococcus aureus (MRSA) in a biological sample
    10.
    发明申请
    Method of determining types I, II, III, IV or V or methicillin-resistant staphylococcus aureus (MRSA) in a biological sample 有权
    在生物样品中测定I，II，III，IV或V型或耐甲氧西林金黄色葡萄球菌（MRSA）的方法

    公开(公告)号：US20110312876A1

    公开(公告)日：2011-12-22

    申请号：US12930663

    申请日：2011-01-13

    申请人： Scott Elliot Gygax ,  Christina Lim Overmyer ,  Lisa A. DeSalvia ,  Martin E. Adelson ,  Eli Mordechai

    发明人： Scott Elliot Gygax ,  Christina Lim Overmyer ,  Lisa A. DeSalvia ,  Martin E. Adelson ,  Eli Mordechai

    IPC分类号： A61K38/14 ,  A61P31/04 ,  C12Q1/68 ,  A61K31/5377 ,  C40B30/00 ,  C07H21/04

    CPC分类号： C12Q1/689 ,  A61K31/5377 ,  A61K38/12 ,  A61K38/14 ,  C12Q1/6844 ,  C12Q2600/16

    摘要： Disclosed are diagnostic methods for determining a subtype of methicillin-resistant Staphylococcus aureus (MRSA) in a biological sample of a mammal. Methods include providing a biological sample of the mammal, performing a PCR analysis of the biological sample, and analyzing the PCR amplicons with respect to their sizes so as to determine for type I, type II, type III, type IV or type V MRSA that may be present in the biological sample. Further example embodiments include using at least one mecA primer pair and/or using at least one Staphylococcus aureus nuc primer pair in the PCR analysis. Further disclosed are methods for screening populations for MRSA, and methods of treating a mammal testing positive for Type IV MRSA. Also disclosed are kits for determining a MRSA subtype in a mammal and isolated primers that may be used in the present methods and kits.

    摘要翻译： 公开了用于确定哺乳动物生物样品中耐甲氧西林金黄色葡萄球菌（MRSA）亚型的诊断方法。 方法包括提供哺乳动物的生物样品，对生物样品进行PCR分析，并根据其大小对PCR扩增子进行分析，以确定I型，II型，III型，IV型或V型MRSA， 可能存在于生物样品中。 另外的实施例包括在PCR分析中使用至少一个mecA引物对和/或使用至少一种金黄色葡萄球菌引物对。 进一步披露的是用于筛选MRSA群体的方法以及治疗IV型MRSA阳性的哺乳动物的方法。 还公开了用于测定哺乳动物中MRSA亚型的试剂盒和可用于本发明方法和试剂盒的分离的引物。