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公开(公告)号：US20200376283A1
公开(公告)日：2020-12-03
申请号：US16883489
申请日：2020-05-26
发明人： Markus Enderle , Ulrich Biber , Ovidiu Jurjut
摘要： A two-part NMS-test bench is provided with which instruments, generator voltages, and surgery modes can be evaluated with regard to neuromuscular stimulations. By separating the NMS-test bench in a first part for application of the instrument and in the second part for evaluation of the physiological effect on nerves, a measurement free of artifacts is possible. The spatial and timely separation of the RF-application from the recording of the compound action potentials makes RF-disturbances ineffective. The electrical signals gained in the instrument test chamber can be pre-processed. The recorded electrical signals emitted from the instrument can be evaluated at the nerve model an arbitrary number of times. The variance involved with the recording of compound action potentials during direct use of the instrument can thus be minimized. The separated test of the signals at the nerve model avoids thermal damage of a prepared nerve and falsification of measurement results.
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公开(公告)号：US09980767B2
公开(公告)日：2018-05-29
申请号：US14295949
申请日：2014-06-04
发明人： Klaus Fischer , Dan Maurice , John Day , Markus Enderle
CPC分类号： A61B18/042 , A61B17/00234 , A61B17/3203 , A61B17/32056 , A61B17/3478 , A61B18/1482 , A61B2017/00269 , A61B2017/22074 , A61B2018/00589 , A61B2018/00601 , A61B2018/1407
摘要： A method for the selective elevation and separation of tissues comprised of multiple layers and a surgical instrument for performing the method. The method may be performed without the requirement of a solid mechanical device insertion or transection through the mucosal layer. In particular, the method and surgical instrument may be used for the selected separation and/or resection of selected portions of benign or malignant tissues (e.g. defining tissue planes, polyp elevation and removal, submucosal tissue tunneling, endoscopic mucosa resection, etc).
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公开(公告)号：US20170360416A1
公开(公告)日：2017-12-21
申请号：US15638649
申请日：2017-06-30
发明人： Klaus Fischer , Mara Szyrach , Markus Enderle
CPC分类号： A61B10/02 , A61B18/02 , A61B90/39 , A61B2017/00809 , A61B2017/306 , A61B2018/00041
摘要： A cryosurgical instrument, in particular a biopsy instrument for transbronchial biopsy, having an elongated instrument base body with a distal and proximal end, in relation to the operational position, a cooled section close to the distal end and which removes tissue, said section being designed such that surrounding biological material adheres thereto, by means of cryoadhesion, when said instrument is in use in the cooled state, and a security section which is provided at a distance from the tissue removal section and which comprises means for preventing or reducing the adhesion of biological material.
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公开(公告)号：US20240074695A1
公开(公告)日：2024-03-07
申请号：US18457596
申请日：2023-08-29
CPC分类号： A61B5/441 , A61B5/004 , A61B5/1032 , A61B5/742 , G16H20/00
摘要： A treatment device allows a treatment of tissue with a treatment medium that does not directly show a tissue trace with manual as well as machine instrument guidance and under adjustment of a treatment plan map, due to preceding treatments. The treatment plan map represents the transformation rules for the treating person. The concept allows the adaption to different patients or patient collectives as well as the individualization of the creation of the treatment plan map with regard to the using treating persons.
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公开(公告)号：US10589299B2
公开(公告)日：2020-03-17
申请号：US14623035
申请日：2015-02-16
发明人： Andreas Fech , Klaus Fischer , Markus Enderle
摘要： The invention relates to a method for mixing at least two fluids using an externally mixing nozzle for medical purposes, which has at least two outlet channels (10, 20) and at least two inlet openings (13, 23) with different or identical cross-sections, wherein two fluids with different volumetric flows and/or different viscosity are sprayed, and wherein the ratio of the cross-sections of the inlet channels (13, 23) and/or the outlet channels (10, 20) corresponds to the ratio of the volumetric flows so that the fluids flow with substantially identical flow speeds through the outlet channels (10, 20) and/or the inlet openings (13, 23). The invention furthermore relates to an externally mixing nozzle, a medical instrument and a medical device for spraying substances, in particular biological material.
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公开(公告)号：US10154786B2
公开(公告)日：2018-12-18
申请号：US14304518
申请日：2014-06-13
摘要： The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.
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公开(公告)号：US20140378960A1
公开(公告)日：2014-12-25
申请号：US14304518
申请日：2014-06-13
IPC分类号： A61B18/12
CPC分类号： A61B5/0084 , A61B5/0075 , A61B18/1477 , A61B2018/00607 , A61B2018/00904 , A61B2018/00982 , A61B2018/1435 , A61B2218/002
摘要： The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.
摘要翻译： 根据本发明的用于电刺激生物组织的器械包括电极（18）以及导光体（21），该光导件连接到通过流体（27）形成的光入口窗口（19） ）。 导光体连接到光分析装置（13），以便响应于HF手术吸收在电极（18）处产生的光，并将其提供给光分析装置（13）， 。 光入口窗（19）布置在光的原点，即立即在电极处，即产生的火花处。 实际上可以避免在光入口窗口（19）上通过烟雾或颗粒沉积对吸收的光的掺假。
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公开(公告)号：US10603095B2
公开(公告)日：2020-03-31
申请号：US15423092
申请日：2017-02-02
发明人： Klaus Fischer , Dan Maurice , John Day , Markus Enderle
IPC分类号： A61B18/04 , A61B17/3203 , A61B17/34 , A61B17/3205 , A61B17/00 , A61B18/14 , A61B17/22 , A61B18/00
摘要： A method for the selective elevation and separation of tissues comprised of multiple layers and a surgical instrument for performing the method. The method may be performed without the requirement of a solid mechanical device insertion or transection through the mucosal layer. In particular, the method and surgical instrument may be used for the selected separation and/or resection of selected portions of benign or malignant tissues (e.g. defining tissue planes, polyp elevation and removal, submucosal tissue tunnelling, endoscopic mucosa resection, etc).
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公开(公告)号：US10549041B2
公开(公告)日：2020-02-04
申请号：US14976084
申请日：2015-12-21
发明人： Andreas Fech , Klaus Fischer , Lars Blobel , Waldemar Wandel , Markus Enderle
摘要： The invention relates to an instrument head, comprising: an exit opening (23); a first feed line (11) for the feed of a first fluid; a second feed line (12) for the feed of a second fluid; a reservoir (24) for storing the fluid fed via the second feed line (12); wherein the reservoir (24) is in fluid communication with the first feed line (11) and/or is adapted to be brought in fluid communication with the first feed line (11) via at least a valve (25) arranged in the instrument head, to deliver fluid stored in the reservoir (24) via the exit opening (23).
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10.发明申请公开(公告)号：US20170071652A1
公开(公告)日：2017-03-16
申请号：US15259965
申请日：2016-09-08
发明人： Markus Enderle , Klaus Fischer , Thomas Stäbler
CPC分类号： A61B18/042 , A61B2018/00494 , A61B2018/00577 , A61B2018/00607 , A61B2018/00702 , A61B2018/00732 , A61B2018/00767 , A61B2018/00982 , A61B2218/005
摘要： The ablation system (10) according to the invention works with an ablation probe (12, 12a) that comprises two alternatingly working spark plasma electrodes (31, 32). They generate a plasma beam (47, 48) having a non-circular cross-section, which beam is to be guided—transversely with respect to the large longitudinal axis of its preferably oval cross-section—over the tissue to be ablated, in particular the mucosa (14). In doing so, it is possible to treat large-area tissue regions by means of a reliable and easily controllable procedure.
摘要翻译： 根据本发明的消融系统（10）与包括两个交替工作的火花等离子体电极（31,32）的消融探针（12,12a）一起工作。 它们产生具有非圆形横截面的等离子体束（47,48），该等离子体束相对于其优选椭圆形横截面的横向要横向于待烧蚀的组织横向引导， 特别是粘膜（14）。 在这样做时，可以通过可靠且容易控制的程序来处理大面积的组织区域。
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