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公开(公告)号:US09107773B2
公开(公告)日:2015-08-18
申请号:US13555056
申请日:2012-07-20
申请人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
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公开(公告)号:US20130070200A1
公开(公告)日:2013-03-21
申请号:US13503842
申请日:2010-10-25
申请人: Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
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公开(公告)号:US09498385B2
公开(公告)日:2016-11-22
申请号:US13503842
申请日:2010-10-25
申请人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela MacFarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela MacFarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
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公开(公告)号:US20120310133A1
公开(公告)日:2012-12-06
申请号:US13555056
申请日:2012-07-20
申请人: Eugene De Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene De Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号: A61F9/00
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
摘要翻译: 适形覆盖物包括具有刚性以抵抗角膜上的运动的外部部分和与角膜接触的内部部分并提供用于上皮再生的环境。 覆盖物的内部部分可以以许多方式配置,以便至少部分地符合消融的基质表面,以便矫正视力。 适形的内部部分可以具有至少一些刚性,以便平滑上皮,使得上皮迅速再生并且被覆盖物引导以形成平滑的视觉层。 内部部分可以包括在约1×10 -4 Pa * m 3至约5×10 -4 Pa * m 3的范围内的刚性量,以便至少部分地偏转并符合消融的角膜并使内部部分平滑 的消融量在偏转时具有一定的压力。
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公开(公告)号:US08459793B2
公开(公告)日:2013-06-11
申请号:US13615111
申请日:2012-09-13
申请人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene de Juan, Jr. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
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公开(公告)号:US20130025606A1
公开(公告)日:2013-01-31
申请号:US13615111
申请日:2012-09-13
申请人: Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
发明人: Eugene de Juan, JR. , Cary J. Reich , Yair Alster , K. Angela Macfarlane , Doug Rimer , Douglas Sutton , Dean Carson , Enrique Barragan , Matt Clarke , Ashley Tuan , Brian Levy
IPC分类号: A61F9/00
CPC分类号: G02C7/047 , A61F2/145 , A61F2/147 , A61F9/00 , A61F9/0017 , A61F9/008 , A61F9/00802 , A61F9/00804 , A61F9/013 , A61F9/0136 , A61F9/04 , A61F13/124 , A61F2009/00853 , A61F2009/00893 , A61F2250/0029 , A61L27/18 , A61L2430/16 , G02C7/048 , G02C7/049 , G02C2202/06 , C08L83/04
摘要: A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10−4 Pa*m3 to about 5×10−4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.
摘要翻译: 适形覆盖物包括具有刚性以抵抗角膜上的运动的外部部分和与角膜接触的内部部分并提供用于上皮再生的环境。 覆盖物的内部部分可以以许多方式配置,以便至少部分地符合消融的基质表面,以便矫正视力。 适形的内部部分可以具有至少一些刚性,以便平滑上皮,使得上皮迅速再生并且被覆盖物引导以形成平滑的视觉层。 内部部分可以包括在约1×10 -4 Pa * m 3至约5×10 -4 Pa * m 3的范围内的刚性量,以便至少部分地偏转并符合消融的角膜并使内部部分平滑 的消融量在偏转时具有一定的压力。
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公开(公告)号:US20120046688A1
公开(公告)日:2012-02-23
申请号:US13283969
申请日:2011-10-28
申请人: Ryan Abbott , W. Martin Belef , Dean Carson , Peter Fitzgerald , Ronald J. Jabba , James Nielsen , Peter Thornton
发明人: Ryan Abbott , W. Martin Belef , Dean Carson , Peter Fitzgerald , Ronald J. Jabba , James Nielsen , Peter Thornton
IPC分类号: A61B17/08
CPC分类号: A61B17/0057 , A61B17/12122 , A61B17/221 , A61B2017/00247 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00619 , A61B2017/00623 , A61B2017/00867 , A61B2017/00893 , A61B2017/0412 , A61B2017/0419 , A61B2017/0422 , A61B2017/22047 , A61B2017/2926 , A61B2017/306 , A61B2018/00392
摘要: Systems and methods for treating internal tissue defects, such as septal defects, with clip-based devices are provided. An exemplary clip-based device includes a tubular body having at least a first and a second deflectable member coupled thereto. The first and second members are coupled on opposite ends of the tubular body and configured to deflect between an undeployed configuration and a deployed configuration. In the deployed configuration, each member extends outwardly away from the tubular body in a position configured to abut a tissue surface. The first and second members are preferably configured to maintain a tissue wall therebetween and at least partially close any opening in the tissue wall.
摘要翻译: 提供了用于基于夹子的装置来治疗内部组织缺陷(例如间隔缺损)的系统和方法。 示例性的基于夹子的装置包括具有与其连接的至少第一和第二可偏转构件的管状体。 第一和第二构件联接在管状体的相对端部并且构造成在未部署构造和展开配置之间偏转。 在所展开的构造中,每个构件在构造成邻接组织表面的位置中向外远离管状体延伸。 第一和第二构件优选地构造成在其间保持组织壁并且至少部分地关闭组织壁中的任何开口。
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公开(公告)号:US20110093007A1
公开(公告)日:2011-04-21
申请号:US12819911
申请日:2010-06-21
申请人: Ryan Abbott , W. Martin Belef , Dean Carson , Taylor A. Heanue , Ronald J. Jabba , Anthony J. Pantages
发明人: Ryan Abbott , W. Martin Belef , Dean Carson , Taylor A. Heanue , Ronald J. Jabba , Anthony J. Pantages
IPC分类号: A61B17/00
CPC分类号: A61B17/0057 , A61B5/0215 , A61B5/415 , A61B5/418 , A61B17/0644 , A61B17/068 , A61B17/29 , A61B2017/00243 , A61B2017/00292 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/061 , A61B2017/0649 , A61B2017/22047 , A61B2017/2912 , A61B2090/0811 , A61F2002/9517
摘要: A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus, devices for controlling delivery of the treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, and a proximal control device for controlling delivery of the implantable apparatus, among others.
摘要翻译: 提供一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置,用于控制治疗装置的输送的装置和用于治疗间隔缺损的方法。 可植入治疗装置优选通过中隔壁或其部分植入。 治疗系统可以包括柔性细长主体构件,配置成输送可植入装置的输送装置,以及用于控制可植入装置的输送的近端控制装置等。
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公开(公告)号:US20100234879A1
公开(公告)日:2010-09-16
申请号:US12725282
申请日:2010-03-16
申请人: Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
发明人: Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
IPC分类号: A61B17/03
CPC分类号: A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要: A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译: 提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。 可植入治疗装置优选通过中隔壁或其部分植入。 治疗系统可以包括柔性细长主体构件,配置成输送可植入装置的输送装置,被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。
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公开(公告)号:US07686828B2
公开(公告)日:2010-03-30
申请号:US11422871
申请日:2006-06-07
申请人: Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
发明人: Ryan Abbott , W. Martin Belef , Dean Carson , Rajiv Doshi , Ronald J. Jabba
CPC分类号: A61B17/0057 , A61B17/064 , A61B17/221 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/0649 , A61B2017/22047 , A61B2017/2926 , A61B2017/306
摘要: A system for treating a septal defect having an implantable treatment apparatus and devices for delivering the implantable treatment apparatus and methods for treating a septal defect are provided. The implantable treatment apparatus is preferably implantable through a septal wall or portion thereof. The treatment system can include a flexible elongate body member, a delivery device configured to deliver the implantable apparatus, a stabilization device configured to stabilize the body member and a positioning device configured to position the delivery device in a desired location.
摘要翻译: 提供了一种用于治疗具有可植入治疗装置的间隔缺损的系统和用于递送可植入治疗装置的装置和用于治疗间隔缺损的方法。 可植入治疗装置优选通过中隔壁或其部分植入。 治疗系统可以包括柔性细长主体构件,配置成输送可植入装置的输送装置,被配置为使身体构件稳定的稳定装置和构造成将输送装置定位在期望位置的定位装置。
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