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    Posterior Segment Drug Delivery
    1.
    发明申请
    Posterior Segment Drug Delivery 有权
    后期药物递送

    公开(公告)号：US20100255061A1

    公开(公告)日：2010-10-07

    申请号：US12696678

    申请日：2010-01-29

    申请人： Eugene de Juan, JR. ,  Yair Alster ,  Steven M. Chamow ,  Kathleen Cogan Farinas ,  Hanson S. Gifford, III ,  K. Angela MacFarlane ,  Cary J. Reich ,  Michael Barrett ,  Randolph E. Campbell ,  Robert George ,  Douglas Sutton

    发明人： Eugene de Juan, JR. ,  Yair Alster ,  Steven M. Chamow ,  Kathleen Cogan Farinas ,  Hanson S. Gifford, III ,  K. Angela MacFarlane ,  Cary J. Reich ,  Michael Barrett ,  Randolph E. Campbell ,  Robert George ,  Douglas Sutton

    IPC分类号： A61F9/00 ,  A61K39/395 ,  A61P27/02 ,  A61K31/5575 ,  A61K31/58 ,  A61F2/14 ,  B23P17/04

    CPC分类号： G01N33/558 ,  A61F9/0017 ,  A61K9/0048 ,  A61K9/0051 ,  A61K31/57 ,  A61K31/573 ,  A61K31/58 ,  A61K38/385 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K2039/505 ,  C07K16/22 ,  C07K2317/24 ,  C07K2317/55 ,  Y10T29/49826

    摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side. Each of the openings on the first side can be connected to each of the openings on the second side with the plurality of interconnecting channels, such that the rate of release of the therapeutic agent can be substantially maintained when one or more of the openings is blocked, for example with particles, cells, bacteria or tissue when the device is implanted for an extended time. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device many comprise an expandable retention structure and an expandable reservoir, such that the device can be delivered from a lumen of a delivery device and expand when positioned in the patient. The therapeutic device may comprises a penetrable barrier to inject therapeutic agent into the device when implanted in the patient.

    摘要翻译： 用于释放治疗剂的治疗装置包括联接到包括储存器的容器的多孔结构。 储存器包括体积大小，当耦合到多孔结构并且植入患者体内时，释放治疗剂量的治疗剂延长的时间。 所述多孔结构可以包括联接到所述储存器的第一侧和与所述患者联接以释放所述治疗剂的第二侧。 多个互连通道可以从第一侧延伸到第二侧，以便将第一侧上的第一多个开口与第二侧上的第二多个开口连接。 第一侧的每个开口可以与多个互连通道连接到第二侧的每个开口，使得当一个或多个开口被阻塞时可以基本上保持治疗剂的释放速度 ，例如当器件长时间植入时，可以使用颗粒，细胞，细菌或组织。 从第一侧延伸到第二侧的通道的长度可以包括大于多孔结构从第一侧到第二侧的距离的有效长度。 治疗装置许多包括可扩张的保留结构和可扩张的储存器，使得该装置可以从输送装置的内腔输送，并且在定位在患者体内时膨胀。 治疗装置可以包括当植入患者时将治疗剂注入装置中的可穿透屏障。

    Posterior segment drug delivery
    2.
    发明授权
    Posterior segment drug delivery 有权
    后段药物递送

    公开(公告)号：US08399006B2

    公开(公告)日：2013-03-19

    申请号：US12696678

    申请日：2010-01-29

    申请人： Eugene de Juan, Jr. ,  Yair Alster ,  Steven M. Chamow ,  Kathleen Cogan Farinas ,  Hanson S. Gifford, III ,  K. Angela Macfarlane ,  Cary J. Reich ,  Michael Barrett ,  Randolph E. Campbell ,  Robert George ,  Douglas Sutton

    发明人： Eugene de Juan, Jr. ,  Yair Alster ,  Steven M. Chamow ,  Kathleen Cogan Farinas ,  Hanson S. Gifford, III ,  K. Angela Macfarlane ,  Cary J. Reich ,  Michael Barrett ,  Randolph E. Campbell ,  Robert George ,  Douglas Sutton

    IPC分类号： A61M37/00 ,  A61M31/00

    CPC分类号： G01N33/558 ,  A61F9/0017 ,  A61K9/0048 ,  A61K9/0051 ,  A61K31/57 ,  A61K31/573 ,  A61K31/58 ,  A61K38/385 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K2039/505 ,  C07K16/22 ,  C07K2317/24 ,  C07K2317/55 ,  Y10T29/49826

    摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side. Each of the openings on the first side can be connected to each of the openings on the second side with the plurality of interconnecting channels, such that the rate of release of the therapeutic agent can be substantially maintained when one or more of the openings is blocked, for example with particles, cells, bacteria or tissue when the device is implanted for an extended time. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device many comprise an expandable retention structure and an expandable reservoir, such that the device can be delivered from a lumen of a delivery device and expand when positioned in the patient. The therapeutic device may comprises a penetrable barrier to inject therapeutic agent into the device when implanted in the patient.

    摘要翻译： 用于释放治疗剂的治疗装置包括联接到包括储存器的容器的多孔结构。 储存器包括体积大小，当耦合到多孔结构并且植入患者体内时，释放治疗剂量的治疗剂延长的时间。 所述多孔结构可以包括联接到所述储存器的第一侧和与所述患者联接以释放所述治疗剂的第二侧。 多个互连通道可以从第一侧延伸到第二侧，以便将第一侧上的第一多个开口与第二侧上的第二多个开口连接。 第一侧的每个开口可以与多个互连通道连接到第二侧的每个开口，使得当一个或多个开口被阻塞时可以基本上保持治疗剂的释放速度 ，例如当器件长时间植入时，可以使用颗粒，细胞，细菌或组织。 从第一侧延伸到第二侧的通道的长度可以包括大于多孔结构从第一侧到第二侧的距离的有效长度。 治疗装置许多包括可扩张的保留结构和可扩张的储存器，使得该装置可以从输送装置的内腔输送，并且在定位在患者体内时膨胀。 治疗装置可以包括当植入患者时将治疗剂注入装置中的可穿透屏障。

    Waste water outlet
    5.
    发明授权
    Waste water outlet 失效
    废水出口

    公开(公告)号：US08201581B2

    公开(公告)日：2012-06-19

    申请号：US12088409

    申请日：2006-08-22

    申请人： Robert George

    发明人： Robert George

    IPC分类号： F16K11/085

    CPC分类号： E03C1/22 ,  E03B1/044 ,  Y02A20/302 ,  Y10T137/86493 ,  Y10T137/8782

    摘要： The present invention provides a waste for an item of sanitary ware generating grey water, the waste comprising: (i) an inlet for admitting grey water; (ii) first and second outlets configured to discharge grey water, the first outlet being arranged to connect to a drainage system, and the second outlet being arranged to connect to a recycling system; (iii) a valve configured to selectively direct water to the first outlet or the second outlet, the valve being located between the inlet and the first and the second outlets, wherein the valve is operable between the first and the second positions, the valve connecting the inlet to the first outlet in the first position and the valve connecting the inlet to the second outlet in the second position; and (iv) a plug dimensioned to fit the inlet and configured to operate the valve by manipulation of the plug.

    摘要翻译： 本发明提供了一种产生灰水的卫生洁具的废物，废物包括：（i）用于承认灰水的入口; （ii）构造成排出灰水的第一和第二出口，所述第一出口布置成连接到排水系统，并且所述第二出口被布置成连接到再循环系统; （iii）构造成选择性地将水引导到第一出口或第二出口的阀，阀位于入口与第一和第二出口之间，其中阀可在第一和第二位置之间操作，阀连接 在第一位置的第一出口的入口和在第二位置将入口连接到第二出口的阀; 以及（iv）尺寸适合于入口并被构造成通过操纵插头来操作阀的插头。

    Computerized methods for data loggers
    8.
    发明申请
    Computerized methods for data loggers 审中-公开

    公开(公告)号：US20050144355A1

    公开(公告)日：2005-06-30

    申请号：US11064487

    申请日：2005-02-23

    申请人： Jonathan Dorny ,  Robert George

    发明人： Jonathan Dorny ,  Robert George

    IPC分类号： G06F1/32 ,  G06F9/445 ,  G06F12/14 ,  G06F15/00 ,  G06F19/00

    CPC分类号： G06F1/3203 ,  G06F8/654 ,  Y02D10/42

    摘要： The present invention provides methods for operating data loggers and in particular, software techniques useful for controlling the critical functions of a low-power-battery-operated data logger. One method initializes various memory locations upon a detection of new firmware. Another method allows a processor system belonging to a data logger to receive a high baud rate data stream while being operated in a sleep mode. Yet another method provides a highly efficient process for estimating the remaining battery capacity of a data logger's primary power source. Finally, a method is provided for protecting volatile variables during a disruption of primary power. The protected variables are written to non-volatile memory using parasitic power only.

    Distributed read and write caching implementation for optimized input/output applications
    9.
    发明授权
    Distributed read and write caching implementation for optimized input/output applications 有权
    分布式读写缓存实现，用于优化的输入/输出应用程序

    公开(公告)号：US06681292B2

    公开(公告)日：2004-01-20

    申请号：US09940835

    申请日：2001-08-27

    申请人： Kenneth C. Creta ,  Mike Bell ,  Robert George ,  Bradford B Congdon ,  Robert Blankenship ,  Duane January

    发明人： Kenneth C. Creta ,  Mike Bell ,  Robert George ,  Bradford B Congdon ,  Robert Blankenship ,  Duane January

    IPC分类号： G06F1300

    CPC分类号： G06F12/0848 ,  G06F12/0802 ,  G06F12/0833 ,  G06F13/4059

    摘要： A caching input/output hub includes a host interface to connect with a host. At least one input/output interface is provided to connect with an input/output device. A write cache manages memory writes initiated by the input/output device. At least one read cache, separate from the write cache, provides a low-latency copy of data that is most likely to be used. The at least one read cache is in communication with the write cache. A cache directory is also provided to track cache lines in the write cache and the at least one read cache. The cache directory is in communication with the write cache and the at least one read cache.

    摘要翻译： 缓存输入/输出集线器包括与主机连接的主机接口。 提供至少一个输入/输出接口以与输入/输出设备连接。 写缓存管理由输入/输出设备发起的存储器写入。 与写缓存分开的至少一个读缓存提供了最可能使用的低延迟数据副本。 至少一个读高速缓存与写高速缓存通信。 还提供缓存目录以跟踪写入高速缓存和至少一个读取高速缓存中的高速缓存行。 缓存目录与写缓存和至少一个读高速缓存通信。

    Reference based sizing
    10.
    发明授权
    Reference based sizing 有权
    基于参考的大小

    公开(公告)号：US09396555B2

    公开(公告)日：2016-07-19

    申请号：US14847189

    申请日：2015-09-08

    申请人： Robert George

    发明人： Robert George

    IPC分类号： G06K9/48 ,  G06T7/60 ,  G06T5/00 ,  G06K9/62

    CPC分类号： G06T7/602 ,  G06K9/00671 ,  G06K9/6202 ,  G06T5/002 ,  G06T7/62 ,  G06T2207/10004 ,  G06T2207/30124

    摘要： Techniques for determining the dimensions of an object. The user of a smartphone snaps a digital photograph which includes both a reference item and the object. A processor then determines the object dimensions by analyzing the digital photo to determine the boundaries of the object and the reference item. From this boundary information, the dimensions of the object can be estimated without further interaction from the user. In optional aspects, the object boundaries can be used to identify the type of object against a database of objects. The object type may be taken into account when presenting the measured dimensions. For example, in a case where the object is recognized as being a pair of women's slacks, the resulting dimensions may be presented as a list of typical dimensions for such a garment including waist, hips, front rise, inseam, leg opening, etc.

    摘要翻译： 用于确定对象尺寸的技术。 智能手机的用户拍摄包括参考项目和对象的数字照片。 然后，处理器通过分析数字照片来确定对象和参考项目的边界来确定对象尺寸。 从该边界信息，可以估计对象的尺寸，而不需要用户的进一步交互。 在可选方面，对象边界可用于根据对象数据库识别对象的类型。 当呈现测量尺寸时，可以考虑对象类型。 例如，在将物体识别为一对女性休闲裤的情况下，所得到的尺寸可以呈现为包括腰部，臀部，前臀，内侧，腿部开口等的这种服装的典型尺寸的列表。