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公开(公告)号：US20210393565A1
公开(公告)日：2021-12-23
申请号：US17296450
申请日：2019-11-28
发明人： Bodo SPECKMANN , Ines OCHROMBEL , Martin SCHILLING , Mario GOMEZ , Michael SCHWARM , Stefan PELZER , Jessica KLEINBÖLTING , Thomas BERNGRUBER
IPC分类号： A61K31/201 , A61K31/202
摘要： The invention relates to preparation comprising at least one omega-3 or omega-6 fatty acid component selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), alpha linolenic acid, stearidonic acid, eicosatetraenoic acid, docosapentaenoic acid, linoleic acid, γ-linolenic acid, or arachidonic acid (ARA) and/or derivatives thereof for use to increase the formation of one or more specialized pro-resolving lipid mediators (SPM) by gastrointestinal microorganisms in the gastrointestinal tract of humans or animals wherein the polyunsaturated fatty acid component comprises an omega-3 or omega-6 fatty acid salt.
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公开(公告)号：US20240156882A1
公开(公告)日：2024-05-16
申请号：US18279995
申请日：2022-02-28
IPC分类号： A61K35/747 , A23L33/135 , A61K9/48 , A61K31/7048
CPC分类号： A61K35/747 , A23L33/135 , A61K9/4891 , A61K31/7048
摘要： The current invention concerns preparations comprising at least one probiotic strain belonging to the species Lactobacillus helveticus, Lactobacillus rhamnosus (Lacticaseibacillus rhamnosus), Lactobacillus mucosae (Limosilactobacillus mucosae), and Lactobacillus johnsonii and anthocyanins.
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公开(公告)号：US20230128187A1
公开(公告)日：2023-04-27
申请号：US17788239
申请日：2020-11-27
发明人： Bodo SPECKMANN , Michael SCHWARM , Stefan PELZER , Thomas BERNGRUBER , Marco GOBBETTI , Raffaella DI CAGNO
IPC分类号： A61K35/747 , C12N1/20 , A61P1/14 , A61K35/742 , A61K35/744 , A23L33/135 , A23K10/18 , A23K50/40
摘要： A preparation comprising probiotic strains belonging to the genera Bacillus sp., Lactobacillus sp., optionally Pediococcus sp. as viable cells or cytoplasmic extract thereof, and proteases, wherein the strains can degrade peptide sequences of gliadins. The preparation can be used to produce gluten-free foods from gluten-containing cereals or to treat gluten-related disorders.
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公开(公告)号：US20210392935A1
公开(公告)日：2021-12-23
申请号：US17296465
申请日：2019-11-28
发明人： Bodo SPECKMANN , Ines OCHROMBEL , Martin SCHILLING , Mario GOMEZ , Michael SCHWARM , Stefan PELZER , Jessica KLEINBÖLTING , Thomas BERNGRUBER
IPC分类号： A23L33/12 , A23L33/135 , A23L33/17 , A61K31/202
摘要： The invention relates to preparation comprising at least one probiotic strain belonging to the genus Bacillus megaterium, and a polyunsaturated fatty acid component comprising at least one omega-3 or omega-6 fatty acid selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), arachidonic acid (ARA), alpha linolenic acid, stearidonic acid, eicosatetraenoic acid, docosapentaenoic acid, linoleic acid, γ-linolenic acid, wherein the polyunsaturated fatty acid component comprises an omega-3 or omega-6 fatty acid salt. The invention further relates to use of the inventive preparation as a feed or food supplement, pharmaceutical product, feed-or foodstuff compositions and for topical applications.
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公开(公告)号：US20240180978A1
公开(公告)日：2024-06-06
申请号：US18279388
申请日：2022-02-28
IPC分类号： A61K35/747 , A23L33/135 , A23L33/175 , A61K31/405 , C12N1/20 , C12R1/24 , C12R1/25
CPC分类号： A61K35/747 , A23L33/135 , A23L33/175 , A61K31/405 , C12N1/20 , C12R2001/24 , C12R2001/25
摘要： The current invention concerns preparations comprising probiotic strains belonging to the genus Lactobacillus in combination with the amino acid L-tryptophan.
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公开(公告)号：US20230042485A1
公开(公告)日：2023-02-09
申请号：US17788224
申请日：2020-11-27
发明人： Bodo SPECKMANN , Michael SCHWARM , Stefan PELZER , Thomas BERNGRUBER , Marco GOBBETTI , Raffaella DI CAGNO
IPC分类号： C12Q1/04 , A61K35/741 , C12Q1/37 , C12N1/20 , G01N33/68
摘要： This invention concerns a process to identify consortia of probiotic strains belonging to e.g. the genera Lactobacillus, Bacillus, Pediococcus, and Weissella that can be used in preparations for food supplement, food production, and pharmaceutical applications with the intention to execute a safe and rapid degradation of gluten to non-toxic, non-immunogenic digests.
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公开(公告)号：US20220088091A1
公开(公告)日：2022-03-24
申请号：US17049155
申请日：2019-04-18
IPC分类号： A61K35/742 , A61K31/198 , A61K38/05 , A61K9/48 , A61K31/07 , A61K31/51 , A61K31/525 , A61K31/455 , A61K31/197 , A61K31/4415 , A61K31/4188 , A61K31/519 , A61K31/714 , A61K31/375 , A61K31/593 , A61K31/355 , A61K31/122 , A61K33/04 , A61K33/26 , A61K33/00 , A61K33/06 , A61K33/24 , A61K33/34 , A61K33/30 , A61K33/32 , A61K33/18 , A61K31/702 , A61K31/733 , A61K36/31 , A61K36/63 , A61K36/9066 , A61K36/9068 , A61K36/8962 , A61K35/748 , A61K36/258 , A61K36/87 , A61K31/05 , A61K36/738 , A23K10/18 , A23K20/147 , A23K40/30 , A23K20/174 , A23K20/20 , A23K20/163 , A23K10/30 , A23L33/135 , A23L33/175 , A23L33/18 , A23L33/15 , A23L33/16 , A23L33/125 , A23L33/105 , A23L33/00
摘要： A synbiotic preparation may include at least one probiotic strain and at least one amino acid or derivative thereof selected from glutamine, glutamic acid or salts thereof, conjugated glutamine, or oligopeptides of 2-10 amino acid units in length, wherein the amino acid units may be natural amino acids, and at least one amino acid unit being a glutamine or glutamic acid unit.
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公开(公告)号：US20220312816A1
公开(公告)日：2022-10-06
申请号：US17612755
申请日：2020-05-18
发明人： Bodo SPECKMANN , Michael SCHWARM , Ines OCHROMBEL , Stefan PELZER
IPC分类号： A23L33/12 , A23L33/175 , A23C19/093 , A23C9/13 , A61K31/202 , A61K9/00
摘要： The invention discloses preparations for use in enhancing formation of short-chain fatty acids (SCFAs) in a subject for treating or preventing a disease or disorder comprising at least one omega-3 fatty acid salt having an organic counter ion selected from lysine, arginine, ornithine, choline and mixtures of the same, wherein the omega-3 fatty acid is selected from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and a colon-specific delivery system.
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9.发明申请公开(公告)号：US20220265749A1
公开(公告)日：2022-08-25
申请号：US17631320
申请日：2020-07-30
发明人： Mario GOMEZ , Bodo SPECKMANN , Michael SCHWARM , Oliver WERZ
IPC分类号： A61K36/324 , A61K31/202 , A61K47/12 , A61K47/36 , A61K47/14 , A23L33/00 , A23L33/105 , A23L33/12 , A23L33/175 , A23K10/30 , A23K20/158 , A23K20/142 , A23K20/105 , A23K20/163
摘要： Preparations may include at least one extract of gum resins from Boswellia species and at least one omega-3 fatty acid salt selected from eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Surprisingly, such combinations of extracts of gum resins from Boswellia species and polyunsaturated fatty acid salt can cause a marked and unexpected increase in the biosynthesis of specialized pro-resolving mediators (SPM) in a synergistic manner, proposing benefit for resolution of inflammatory conditions.
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公开(公告)号：US20220211732A1
公开(公告)日：2022-07-07
申请号：US17613220
申请日：2020-05-18
发明人： Bodo SPECKMANN , Christopher STUDTE
IPC分类号： A61K31/7004 , A61K31/202 , A61K31/732 , A61K31/716 , A61K31/719 , A61K31/702 , A61K31/736 , A61K9/48 , A61P1/14
摘要： The invention discloses preparations comprising L-rhamnose, and the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in the form of either free fatty acids, fatty acid salts having an organic counter ion selected from lysine, arginine, ornithine, choline and mixtures of the same, or mixtures of free fatty acids and omega-3 fatty acid salts having an organic counter ion selected from lysine, arginine, ornithine, choline and use of a preparation as a feed or food supplement or in pharmaceutical compositions.
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