利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

16 条记录 (耗时 0.023 秒)

    Volumetric grafts for treatment of fistulae and related methods and systems
    1.
    发明申请
    Volumetric grafts for treatment of fistulae and related methods and systems 有权
    用于治疗瘘的体积移植物及相关方法和系统

    公开(公告)号：US20080004657A1

    公开(公告)日：2008-01-03

    申请号：US11415403

    申请日：2006-05-01

    申请人： F. Obermiller ,  Michael Hiles ,  Matthew Graham ,  Clay Fette

    发明人： F. Obermiller ,  Michael Hiles ,  Matthew Graham ,  Clay Fette

    IPC分类号： A61F2/04

    CPC分类号： A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61M27/00

    摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.

    摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。

    Fistula graft with deformable sheet-form material
    2.
    发明申请
    Fistula graft with deformable sheet-form material 有权
    具有可变形片状材料的瘘移植物

    公开(公告)号：US20070088445A1

    公开(公告)日：2007-04-19

    申请号：US11414682

    申请日：2006-04-28

    申请人： Umesh Patel ,  F. Obermiller ,  Clay Fette ,  Matthew Graham

    发明人： Umesh Patel ,  F. Obermiller ,  Clay Fette ,  Matthew Graham

    IPC分类号： A61F2/04

    CPC分类号： A61L27/3604 ,  A61B17/0057 ,  A61B2017/00641 ,  A61K35/22 ,  A61K35/38 ,  A61L31/005

    摘要： Described are medical products, systems, and methods for treating fistulae having a primary opening, such as in the alimentary canal. Certain methods of the invention include providing an implantable material including a compliant sheet form biocompatible material, and forcing this sheet form biocompatible material into the primary opening so as to deform the sheet form biocompatible material to conform to and block the primary opening. The biocompatible material preferably comprises a remodelable material, for example, a remodelable extracellular matrix material such as submucosa.

    摘要翻译： 描述了用于治疗具有主要开口的瘘的医疗产品，系统和方法，例如在消化道中。 本发明的某些方法包括提供可植入材料，其包括顺应性片材形式的生物相容性材料，并且迫使该片材形成生物相容性材料进入主要开口，以使片材形式的生物相容性材料变形以符合和阻止初级开口。 生物相容性材料优选包含可重塑材料，例如可重塑的细胞外基质材料，例如粘膜下层。

    FUEL CELL STACK HAVING A STRUCTURAL HEAT EXCHANGER
    5.
    发明申请
    FUEL CELL STACK HAVING A STRUCTURAL HEAT EXCHANGER 审中-公开
    具有结构热交换器的燃料电池堆

    公开(公告)号：US20130034790A1

    公开(公告)日：2013-02-07

    申请号：US13566347

    申请日：2012-08-03

    申请人： Matthew Graham ,  James Braun ,  Thomas Pavlik

    发明人： Matthew Graham ,  James Braun ,  Thomas Pavlik

    IPC分类号： H01M8/04

    CPC分类号： H01M8/0263 ,  H01M8/0228 ,  H01M8/0256 ,  H01M8/0271 ,  H01M8/242

    摘要： Disclosed are fuel cell stacks incorporating heat exchangers capable of also acting as members to compress the fuel cell stack. Heat exchange through conduction is enabled by placing the heat exchanger into contact with the edges of the bipolar plates. A compressive force within the fuel cell stack is achieved by placing the heat exchanger in tension between the endplates at the opposite ends of the fuel cell stack.

    摘要翻译： 公开了包括热交换器的燃料电池堆，其也可以充当构件以压缩燃料电池堆。 通过将热交换器与双极板的边缘接触来实现通过传导的热交换。 通过将热交换器在燃料电池堆的相对端处的端板之间放置张力来实现燃料电池堆内的压缩力。

    Energy sensors for light beam alignment
    6.
    发明授权
    Energy sensors for light beam alignment 有权
    用于光束对准的能量传感器

    公开(公告)号：US08993976B2

    公开(公告)日：2015-03-31

    申请号：US13249504

    申请日：2011-09-30

    申请人： Matthew Graham ,  Steven Chang ,  Jim Crouch ,  Igor Fomenkov

    发明人： Matthew Graham ,  Steven Chang ,  Jim Crouch ,  Igor Fomenkov

    IPC分类号： G01J1/42 ,  G03F7/20 ,  H05G2/00 ,  G01J1/16

    CPC分类号： G03F7/70033 ,  H05G2/003 ,  H05G2/008

    摘要： An apparatus includes a drive laser system producing an amplified light beam of pulses that travels along a drive axis; a beam delivery system that directs the amplified light beam of pulses toward a target region; a target material delivery system that provides a target mixture containing a target material in the target region; two or more sensors radially separated from a main axis that crosses the target region, the two or more sensors being configured to detect energy of ultraviolet electromagnetic radiation emitted from a plasma state of the target material when the amplified light beam of pulses intersects the target mixture; and a controller that receives the output from the two or more sensors. The controller is configured to estimate a relative radial alignment between the target mixture and the drive axis within the target region based on an analysis of the detected energy.

    摘要翻译： 一种装置包括驱动激光系统，其产生沿驱动轴线行进的放大的脉冲光束; 射束传送系统，其将放大的脉冲光束朝向目标区域引导; 目标材料输送系统，其在目标区域中提供含有目标材料的目标混合物; 两个或更多个传感器与跨越目标区域的主轴径向分离，两个或更多个传感器被配置为当被放大的脉冲光束与目标混合物相交时，检测从目标材料的等离子体状态发射的紫外电磁辐射的能量 ; 以及接收来自两个或更多个传感器的输出的控制器。 控制器被配置为基于对所检测的能量的分析来估计目标混合物和目标区域内的驱动轴之间的相对径向对准。

    Washable, Hands-Free Hydration Glove for Unencumbered Motion
    8.
    发明申请
    Washable, Hands-Free Hydration Glove for Unencumbered Motion 有权

    公开(公告)号：US20210235794A1

    公开(公告)日：2021-08-05

    申请号：US17163716

    申请日：2021-02-01

    申请人： Matthew Graham

    发明人： Matthew Graham

    IPC分类号： A41D19/00

    摘要： A hydration device wherein a customized bladder is secured in a fixed position within a customized glove covering the topside surface area of a hand and the full 360-degree surface area of a forearm. A chamber stitched into an internal surface of the glove and a reclosable fastener secure the bladder's fixed position. The bladder is constructed with additional material on its sides, so that it conforms to the shape of and distributes the weight of its contents 360 degrees along the contours of the appendages. Two holes stitched into the outer portion of the glove expose the bladder's reclosable aperture for filling and a spout for extracting the bladder's contents. The bladder's contoured, 360-degree design impels the hydration device to lay fitted along the appendages with the spout purposefully positioned in a mouth's path during a normal arm swing, thereby promoting the user to maintain unaltered motion while drinking.

    PEPTIDE-CROSSLINKED BIOACTIVE POLYMERIC MATERIALS
    9.
    发明申请
    PEPTIDE-CROSSLINKED BIOACTIVE POLYMERIC MATERIALS 审中-公开
    肽交联的生物聚合材料

    公开(公告)号：US20140171619A1

    公开(公告)日：2014-06-19

    申请号：US14122903

    申请日：2012-05-25

    申请人： Matthew Becker ,  Matthew Graham ,  Frank Harris ,  Fei Lin

    发明人： Matthew Becker ,  Matthew Graham ,  Frank Harris ,  Fei Lin

    IPC分类号： C07K7/06

    CPC分类号： C07K7/06 ,  C07K7/08

    摘要： A method for creating a peptide crosslinked bioactive polymeric material includes reacting a hydroxy-functionalized small molecule with a amino acid to form an amino acid functionalized monomer, reacting the amino acid functionalized monomer with a urea bond former to form a amino acid-based poly(ester urea), and reacting the amino acid-based poly(ester urea) with a peptide based crosslinker to form the peptide crosslinked bioactive polymeric material.

    摘要翻译： 用于产生肽交联的生物活性聚合物材料的方法包括使羟基官能化的小分子与氨基酸反应以形成氨基酸官能化单体，使氨基酸官能化单体与脲键形成物反应形成基于氨基酸的聚（ 酯脲），并使基于氨基酸的聚（酯尿素）与基于肽的交联剂反应以形成肽交联的生物活性聚合物材料。

    Energy Sensors for Light Beam Alignment
    10.
    发明申请
    Energy Sensors for Light Beam Alignment 有权
    光束对准​​能量传感器

    公开(公告)号：US20130043401A1

    公开(公告)日：2013-02-21

    申请号：US13249504

    申请日：2011-09-30

    申请人： Matthew Graham ,  Steven Chang ,  Jim Crouch ,  Igor Fomenkov

    发明人： Matthew Graham ,  Steven Chang ,  Jim Crouch ,  Igor Fomenkov

    IPC分类号： G01J1/42 ,  G01J1/16

    CPC分类号： G03F7/70033 ,  H05G2/003 ,  H05G2/008

    摘要： An apparatus includes a drive laser system producing an amplified light beam of pulses that travels along a drive axis; a beam delivery system that directs the amplified light beam of pulses toward a target region; a target material delivery system that provides a target mixture containing a target material in the target region; two or more sensors radially separated from a main axis that crosses the target region, the two or more sensors being configured to detect energy of ultraviolet electromagnetic radiation emitted from a plasma state of the target material when the amplified light beam of pulses intersects the target mixture; and a controller that receives the output from the two or more sensors. The controller is configured to estimate a relative radial alignment between the target mixture and the drive axis within the target region based on an analysis of the detected energy.

    摘要翻译： 一种装置包括驱动激光系统，其产生沿驱动轴线行进的放大的脉冲光束; 射束传送系统，其将放大的脉冲光束朝向目标区域引导; 目标材料输送系统，其在目标区域中提供含有目标材料的目标混合物; 两个或更多个传感器与跨越目标区域的主轴径向分离，两个或更多个传感器被配置为当被放大的脉冲波束与目标混合物相交时，检测从目标材料的等离子体状态发射的紫外电磁辐射的能量 ; 以及接收来自两个或更多个传感器的输出的控制器。 控制器被配置为基于对所检测的能量的分析来估计目标混合物和目标区域内的驱动轴之间的相对径向对准。