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公开(公告)号:US08961594B2
公开(公告)日:2015-02-24
申请号:US13485145
申请日:2012-05-31
申请人: Francesco Maisano , Hugo Vanermen , Ottavio Alfieri , Idan Tobis , Andrea Guidotti , Paolo Denti
发明人: Francesco Maisano , Hugo Vanermen , Ottavio Alfieri , Idan Tobis , Andrea Guidotti , Paolo Denti
IPC分类号: A61F2/24
CPC分类号: A61B17/0401 , A61B17/00234 , A61B17/0487 , A61B17/064 , A61B2017/00243 , A61B2017/00783 , A61B2017/0414 , A61B2017/0441 , A61B2017/0464 , A61B2017/0641 , A61F2/2436 , A61F2/2445 , A61F2/2487 , A61F2220/0016 , A61F2220/0075 , A61F2230/0006
摘要: Techniques are described for use with one or more sutures. For some applications, techniques are described for fixedly-coupling two or more sutures to each other. For some applications, such techniques are used for treating a heart valve of a subject. Techniques are also described for treating a heart valve of a subject by coupling leaflets of the heart valve to a support using tissue-piercing elements. Other embodiments are also described.
摘要翻译: 描述了用于一个或多个缝合线的技术。 对于一些应用,描述了将两个或更多个缝合线彼此固定耦合的技术。 对于一些应用,这种技术用于治疗受试者的心脏瓣膜。 还描述了通过使用组织刺穿元件将心脏瓣膜的小叶联合到支撑体上来治疗受试者的心脏瓣膜的技术。 还描述了其它实施例。
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公开(公告)号:US20130046380A1
公开(公告)日:2013-02-21
申请号:US13574088
申请日:2011-01-20
申请人: Francesco Maisano , Hugo Vanermen , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
发明人: Francesco Maisano , Hugo Vanermen , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
IPC分类号: A61F2/24
CPC分类号: A61F2/2454 , A61B17/0401 , A61B17/064 , A61B17/068 , A61B2017/00243 , A61B2017/00407 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0437 , A61B2017/0441 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/0649 , A61F2/2442 , A61F2/2457 , A61F2/246 , A61F2/2487 , A61F2/848 , A61F2/90 , A61F2/915 , A61F2002/8483 , A61F2002/8486 , A61F2220/0008 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要: Apparatus is provided including a stent, which is configured to assume compressed and expanded states. The stent includes one or more elongated members, and two or more rings, which are coupled together by the one or more elongated members and by no other elements of the stent. The rings define respective planes that are generally perpendicular to the elongated members when the stent is in its expanded state. A longitudinal member, having a proximal end and a distal end, is coupled to the stent at the proximal end of the longitudinal member. A tissue anchor is coupled to the distal end of the longitudinal member. Other applications are also described.
摘要翻译: 提供了包括支架的装置,其被构造成承受压缩和膨胀状态。 支架包括一个或多个细长构件和两个或更多个环,其通过一个或多个细长构件而不通过支架的其它元件联接在一起。 这些环限定了当支架处于其膨胀状态时通常垂直于细长构件的相应平面。 具有近端和远端的纵向构件在纵向构件的近端处联接到支架。 组织锚固件联接到纵向构件的远端。 还描述了其它应用。
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公开(公告)号:US08961596B2
公开(公告)日:2015-02-24
申请号:US13188175
申请日:2011-07-21
申请人: Francesco Maisano , Hugo Vanerman , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
发明人: Francesco Maisano , Hugo Vanerman , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
IPC分类号: A61F2/24 , A61B17/04 , A61B17/064 , A61B17/068 , A61F2/915 , A61B17/00 , A61F2/90
CPC分类号: A61B17/0401 , A61B17/064 , A61B17/068 , A61B2017/00243 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/0649 , A61F2/2442 , A61F2/2454 , A61F2/2457 , A61F2/246 , A61F2/2487 , A61F2/90 , A61F2/915 , A61F2220/0016 , A61F2220/0058 , A61F2230/0013 , A61F2230/0054
摘要: Apparatus is provided, including a radially-expandable percutaneous implant, a tissue anchor, and a connecting element shaped so as to provide an annular loop surrounding a proximal portion of the tissue anchor in a manner which enables rotation of the anchor about a central longitudinal axis thereof when surrounded by the annular loop. The apparatus also includes a flexible longitudinal member coupled at a first portion thereof to at least a portion of the percutaneous implant and at a second portion to the connecting element. The annular loop of the connecting element facilitates rotation of the tissue anchor about the central longitudinal axis such that the anchor can rotate about the central longitudinal axis with respect to the annular loop, the flexible longitudinal member, and the percutaneous implant. Other applications are also described.
摘要翻译: 提供了一种设备,包括径向可膨胀的经皮植入物,组织锚固件和连接元件,所述连接元件成形为以能使锚固件围绕中心纵向轴线旋转的方式提供围绕组织锚固件的近端部分的环形环 当被环形环包围时。 该装置还包括柔性纵向构件,其在其第一部分处耦合到经皮植入物的至少一部分,并且在连接元件的第二部分处。 连接元件的环形环有助于围绕中心纵向轴线旋转组织锚固件,使得锚固件可相对于环形环,柔性纵向构件和经皮植入物围绕中心纵向轴线旋转。 还描述了其它应用。
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公开(公告)号:US09241702B2
公开(公告)日:2016-01-26
申请号:US13553081
申请日:2012-07-19
申请人: Francesco Maisano , Hugo Vanerman , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
发明人: Francesco Maisano , Hugo Vanerman , Valery Perevalov , Rephael Hof , Ottavio Alfieri , Idan Tobis
IPC分类号: A61F2/24 , A61B17/04 , A61B17/064 , A61B17/068 , A61F2/915 , A61B17/00 , A61F2/90
CPC分类号: A61B17/0401 , A61B17/064 , A61B17/068 , A61B2017/00243 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0443 , A61B2017/0464 , A61B2017/048 , A61B2017/0488 , A61B2017/0496 , A61B2017/0649 , A61F2/2442 , A61F2/2445 , A61F2/2454 , A61F2/2457 , A61F2/246 , A61F2/2487 , A61F2/90 , A61F2/915 , A61F2220/0016 , A61F2220/0058 , A61F2230/0013 , A61F2230/0054 , A61F2250/0007
摘要: Apparatus is provided including a radially-expandable percutaneous implant shaped so as to define a tension-distributing element. A flexible longitudinal member is coupled at a first portion thereof to at least a portion of the percutaneous implant via the tension-distributing element. The tension-distributing element is configured to distribute tension applied by the flexible longitudinal member along a longitudinal length of the percutaneous implant.
摘要翻译: 提供了包括径向可膨胀的经皮植入物的装置,其被成形为限定张力分配元件。 柔性纵向构件在其第一部分处经由张力分配元件联接到经皮植入物的至少一部分。 张力分配元件构造成沿着经皮植入物的纵向长度分布由柔性纵向构件施加的张力。
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公开(公告)号:US20050131533A1
公开(公告)日:2005-06-16
申请号:US10882031
申请日:2004-06-30
IPC分类号: A61F2/24
CPC分类号: A61F2/2448 , A61F2/2409
摘要: A remodeling mitral annuloplasty ring with a reduced anterior-to-posterior dimension to restore coaptation between the mitral leaflets in mitral valve insufficiency (IMVI). The ring has a generally oval shaped body with a major axis perpendicular to a minor axis, both perpendicular to a blood flow axis. An anterior section lies between anteriolateral and posteriomedial trigones, while a posterior section defines the remaining ring body and is divided into P1, P2, and P3 segments corresponding to the three scallops of the same nomenclature in the posterior leaflet of the mitral valve. The anterior-to-posterior dimension of the ring body is reduced from conventional rings; such as by providing, in atrial plan view, a pulled-in P3 segment. Viewed another way, the convexity of the P3 segment is less pronounced than the convexity of the P1 segment. In addition, the ring body may have a downwardly deflected portion in the posterior section, preferably within the P2 and P3 segments. The downwardly deflected portion may have an apex which is the lowest elevation of the ring body and may be offset with respect to the center of the downwardly deflected portion toward the P1 segment. A sewing cuff may have an enlarged radial dimension of between 5-10 cm, or only a portion of the sewing cuff may be enlarged.
摘要翻译: 重建二尖瓣瓣环成形术环,具有减小的前后尺寸,以恢复二尖瓣关闭不全(IMVI)中的二尖瓣小叶之间的接合。 环具有大致椭圆形的主体,其长轴垂直于短轴,两者垂直于血流轴线。 前段位于前外侧和后内侧三角形之间,而后段限定剩余的环体,并分为对应于二尖瓣后叶中相同命名的三扇贝的P 1,P 2和P 3段 。 环体的前后尺寸从常规环减少; 例如通过在心房平面图中提供一个拉入的P 3区段。 换句话说,P 3段的凸度比P 1段的凸度更不明显。 此外,环体可以在后部中具有向下偏转的部分,优选地在P 2和P 3段内。 向下偏转的部分可以具有顶点,其是环体的最低高度,并且可以相对于朝向P 1段的向下偏转部分的中心偏移。 缝制袖口可以具有在5-10cm之间的放大的径向尺寸,或者仅可以扩大一部分缝合袖口。
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公开(公告)号:US06726717B2
公开(公告)日:2004-04-27
申请号:US10144932
申请日:2002-05-15
IPC分类号: A61F224
CPC分类号: A61F2/2448
摘要: The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterised in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than 3/4.
摘要翻译: 本发明涉及一种二尖瓣环形假体。 在其一个实施例中,二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成,其特征在于, 在所述前半环和所述后半环之间的距离,沿着垂直于所述第一平面并等距于所述联接件的第二平面测量,并且所述假体的所述最大宽度低于3/4。
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公开(公告)号:US20100137980A1
公开(公告)日:2010-06-03
申请号:US12697936
申请日:2010-02-01
IPC分类号: A61F2/24
CPC分类号: A61F2/2448
摘要: An annular prosthesis for a mitral valve that may include a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis. The ratio between the distance between the anterior half-ring and the posterior half-ring, as measured along a second plane, perpendicular to the first plane and equidistant to the couplings, and the maximum width of the prosthesis is lower than ¾.
摘要翻译: 用于二尖瓣的环形假体,其可以包括在限定假体的最大宽度部分的第一横向平面上彼此耦合的后半环和前半环。 沿着第二平面测量的前半环和后半环之间的距离与第一平面垂直并且等距于联轴器的距离以及假体的最大宽度之间的比值小于3。
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公开(公告)号:US20110301704A1
公开(公告)日:2011-12-08
申请号:US13094145
申请日:2011-04-26
申请人: Ottavio Alfieri , Alain F. Carpentier , Francesco Maisano , Patrick McCarthy , Alberto Redaelli
发明人: Ottavio Alfieri , Alain F. Carpentier , Francesco Maisano , Patrick McCarthy , Alberto Redaelli
IPC分类号: A61F2/24
CPC分类号: A61F2/2448 , A61F2/2409 , A61F2/246
摘要: A remodeling mitral annuloplasty ring with a reduced anterior-to-posterior dimension to restore coaptation between the mitral leaflets in mitral valve insufficiency (IMVI). The ring has a generally oval shaped body with a major axis perpendicular to a minor axis, both perpendicular to a blood flow axis. An anterior section lies between anteriolateral and posteriomedial trigones, while a posterior section defines the remaining ring body and is divided into P1, P2, and P3 segments corresponding to the three scallops of the same nomenclature in the posterior leaflet of the mitral valve. The anterior-to-posterior dimension of the ring body is reduced from conventional rings; such as by providing, in atrial plan view, a pulled-in P3 segment. Viewed another way, the convexity of the P3 segment is less pronounced than the convexity of the P1 segment. In addition, the ring body may have a downwardly deflected portion in the posterior section, preferably within the P2 and P3 segments. The downwardly deflected portion may have an apex which is the lowest elevation of the ring body and may be offset with respect to the center of the downwardly deflected portion toward the P1 segment. A sewing cuff may have an enlarged radial dimension of between 5-10 cm, or only a portion of the sewing cuff may be enlarged.
摘要翻译: 重建二尖瓣瓣环成形术环,具有减小的前后尺寸,以恢复二尖瓣关闭不全(IMVI)中的二尖瓣小叶之间的接合。 环具有大致椭圆形的主体,其长轴垂直于短轴,两者垂直于血流轴线。 前部位于前外侧和后内侧三角形之间,而后段限定剩余的环体,并分为对应于二尖瓣后叶中相同命名的三扇贝的P1,P2和P3段。 环体的前后尺寸从常规环减少; 例如通过在心房平面图中提供一个拉入的P3段。 换句话说,P3段的凸度比P1段的凸度更不明显。 此外,环体可以在后部中具有向下偏转的部分,优选地在P2和P3段内。 向下偏转的部分可以具有作为环主体的最低高度的顶点,并且可以相对于朝向P1段的向下偏转部分的中心偏移。 缝制袖口可以具有在5-10cm之间的放大的径向尺寸,或者仅可以扩大一部分缝合袖口。
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公开(公告)号:US08529621B2
公开(公告)日:2013-09-10
申请号:US13416929
申请日:2012-03-09
IPC分类号: A61F2/24
CPC分类号: A61F2/2448
摘要: The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterized in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than ¾.
摘要翻译: 本发明涉及一种二尖瓣环形假体。 在其一个实施例中,二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成,其特征在于, 在所述前半环和所述后半环之间的距离,沿着垂直于所述第一平面并等距于所述联接件的第二平面测量,并且所述假体的所述最大宽度低于¾。
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公开(公告)号:US20120172983A1
公开(公告)日:2012-07-05
申请号:US13416929
申请日:2012-03-09
IPC分类号: A61F2/24
CPC分类号: A61F2/2448
摘要: The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterised in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than 3/4.
摘要翻译: 本发明涉及一种二尖瓣环形假体。 在其一个实施例中,二尖瓣的环形假体由在限定假体的最大宽度部分的第一横向平面上彼此联接的后半环和前半环组成,其特征在于, 在所述前半环和所述后半环之间的距离,沿着垂直于所述第一平面并等距于所述联接件的第二平面测量,并且所述假体的所述最大宽度低于3/4。
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