摘要:
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.
摘要:
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.
摘要:
The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.
摘要:
The invention provides compositions and methods for isolating ligand binding polypeptides for a user-specified ligand, and for isolating small molecule ligands for a user-specified target polypeptide using an improved class of hybrid ligand compounds.
摘要:
A table can be replaced with a view transparently to the application. For example, a data dictionary can specify that the view is to be substituted for the table. At runtime, application operations on the table are redirected to be performed on the view. Validation can be performed to ensure congruence between the table and the view. Can be useful for situations where a view with enhanced functionality is desired to be used in place of the table without re-coding the application.
摘要:
A gravity feed merchandise dispensing device comprises at least one plastic track capable of supporting in tandem a row of similar bottles of the type having an annular neck flange, and has a lead bottle support basket suspended at the front end of the track which is removable and interchangeable with other lead bottle supports so as to accommodate bottles of different heights. The rails of the track have a sloped transition section at the front end of the track which eases movement of bottles off the track and into the basket, and facilitates the front loading of bottles into the track.
摘要:
A thin film solar module including at least one first sub module including a plurality of first thin film solar cells connected with one another in series; and a second sub module connected with the first sub module in parallel, the second sub module including a plurality of second thin film solar cells connected with one another in series. The sub modules are formed on a shared substrate in a monolithic manner, wherein a first connecting cell including the first thin film solar cells and a second connecting cell including the second thin film solar cells are arranged adjacent to one another, spaced apart from each other through an insulation trench and electrically connected with one another through a shared contact. The invention further relates to a method for producing a thin film solar module.
摘要:
The invention relates to an apparatus for input of movements and/or registration of forces, comprising at least one light source, at least one position sensitive device (PSD) and at least one diaphragm, wherein at least one of these three elements is moveable with respect to the two other elements. The light source is arranged at a mounting so that light from the light source is emitted through an opening in the mounting and through the at least one diaphragm onto the at least one PSD.
摘要:
A method for operating a line-side fundamental-frequency-clocked converter is disclosed. The converters has a bridge circuit with, for example three, upper and, for example three, lower semiconductor switches, which are connected to respective positive and negative terminals of a DC link circuit. Center taps of connected pairs of the upper and lower semiconductor switches are connected to the line voltage phases. Two upper or two lower semiconductor switches are simultaneously activated during fundamental frequency operation for a predetermined time period before or after a natural trigger instant of the semiconductor switches caused by a line voltage angle. An estimated line voltage angle for clocking the semiconductor switches is tracked based on two phase currents measured while the two upper or two lower semiconductor switches are simultaneously active.
摘要:
A method and apparatus in which a granular adsorbent, absorbent, chemisorptive, or catalytic material, particularly activated carbon is intermixed with (a) meltable polymer(s), and that the resulting mixture is heated under pressure and pressed into a molded piece (2). We propose to heat the mixture under pressure in a connecting part for a respirator or fan filter unit or in a connecting part (1) for an adapter for a respirator or fan filter unit, thereby positively and/or non-positively compacting it with said connecting part, and to make the connection between said connecting part (1) and said compacted mixture gastight.