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公开(公告)号：US4541429A
公开(公告)日：1985-09-17
申请号：US376686
申请日：1982-05-10
CPC分类号： A61M5/14276 , A61M5/16881 , F16K31/086 , A61M2205/3515
摘要： A miniature implantable magnetically actuated valve relatively insensitive to normally-encountered shock loads includes a housing for containing a movable ferromagnetic valve member. Inlet and outlet passages are provided in the housing at least one of which has an internal valve seat which is engageable by the valve member to close that passage. The valve member is resiliently suspended within the housing by special flat multiply-started spiral springs which permit the valve member only a single degree of freedom toward and away from the valve seat. The valve member is biased in one direction or the other and the valve is actuated transcutaneously by a magnet juxtaposed to the valve outside the body which produces a magnetic force on the valve member which exceeds and opposes the biasing force.
摘要翻译： 对常见的冲击载荷相对不敏感的微型可植入磁力驱动阀包括用于容纳可动铁磁阀构件的壳体。 入口和出口通道设置在壳体中，其中至少一个具有可由阀构件接合以关闭该通道的内部阀座。 阀构件通过特殊的平面多重启动的螺旋弹簧弹性地悬挂在壳体内，这使得阀构件仅允许朝向和离开阀座的单个自由度。 阀构件在一个方向或另一个方向上被偏压，并且通过与主体并排的磁体经常地驱动阀，其在阀构件上产生超过并抵抗偏压力的磁力。
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公开(公告)号：US08940539B2
公开(公告)日：2015-01-27
申请号：US12992552
申请日：2009-05-14
申请人： Timothy Pearcy , James G. Skakoon
发明人： Timothy Pearcy , James G. Skakoon
CPC分类号： G01N35/1002 , A61J1/06 , A61J1/201 , A61J1/2013 , A61J1/2079 , A61J1/2089 , B01L3/0272 , B01L2200/028 , B01L2200/16 , B01L2300/0672 , B01L2300/087 , B01L2400/0478 , B01L2400/049 , B01L2400/0683 , Y10T137/0402 , Y10T436/11 , Y10T436/25 , Y10T436/2575
摘要： A reagent preparation and dispensing device includes a body. A reagent reservoir containing a reagent is disposed within the body. A solution reservoir containing a solution is disposed within the body. The device further includes an activator movably coupled with the body to open the reagent reservoir and the solution reservoir, The activator is operable to mix the solution with the reagent to form a specified amount of a reagent mixture. A dispensing reservoir tip is coupled with the body. The dispensing reservoir tip is sized and shaped to hold the specified amount of the reagent mixture and dispense the specified amount of the reagent mixture from the device.
摘要翻译： 试剂制备和分配装置包括主体。 含有试剂的试剂容器设置在体内。 包含溶液的溶液储存器设置在体内。 所述装置还包括可与所述主体可移动地联接以打开所述试剂储存器和所述溶液储存器的活化剂。所述活化剂可操作以将所述溶液与所述试剂混合以形成指定量的试剂混合物。 分配储存器尖端与主体联接。 分配容器尖端的尺寸和形状适于保持特定量的试剂混合物，并从装置中分配指定量的试剂混合物。
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公开(公告)号：US08911452B2
公开(公告)日：2014-12-16
申请号：US12899677
申请日：2010-10-07
申请人： James G. Skakoon , Robert Wharen , Matthew S. Solar , Kari Parmer , Rudy A. Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas I. Miller , Timothy Alan Parmer , Charles L. Truwit
发明人： James G. Skakoon , Robert Wharen , Matthew S. Solar , Kari Parmer , Rudy A. Mazzocchi , John David , Frank Murdock , David Hatcher , Thomas I. Miller , Timothy Alan Parmer , Charles L. Truwit
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
摘要翻译： 装置和方法提供将电极或其他器械精确地靶向，放置和/或稳定到脑或其他身体器官中，例如治疗严重的震颤或其它神经障碍。 使用任何形式的图像引导进行定向，包括实时MRI，CT或无框架手术导航系统。
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公开(公告)号：US08433422B2
公开(公告)日：2013-04-30
申请号：US11737927
申请日：2007-04-20
申请人： James A. Alexander , James M. Olsen , Chad Q. Cai , Richard T. Stone , James G. Skakoon , Kristin J. Schneider
发明人： James A. Alexander , James M. Olsen , Chad Q. Cai , Richard T. Stone , James G. Skakoon , Kristin J. Schneider
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/086 , A61N1/3752 , A61N2001/083
摘要： An implantable system that includes a lead and an implantable signal generator wherein the plurality of electrical contacts and the plurality of insulating regions on the lead, and the plurality of electrical connectors and the plurality of electrical insulators in the connector block are configured so that each of the plurality of electrical contacts form operable connections to the electronic circuitry through each of the plurality of electrical connector, and the insulating regions and the electrical insulators electrically isolate adjacent operable connections. Leads, and methods are also disclosed.
摘要翻译： 一种包括引线和可植入信号发生器的可植入系统，其中所述多个电触点和所述引线上的所述多个绝缘区域以及所述连接器块中的所述多个电连接器和所述多个绝缘体被配置为使得每个 多个电触头通过多个电连接器中的每一个形成与电子电路的可操作连接，并且绝缘区域和电绝缘体电隔离相邻的可操作连接。 引线和方法也被公开。
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公开(公告)号：US20110238040A1
公开(公告)日：2011-09-29
申请号：US13155127
申请日：2011-06-07
IPC分类号： A61M25/00
CPC分类号： A61M25/008 , A61B5/6864 , A61B2017/3407 , A61B2017/347 , A61B2017/3492 , A61B2090/103 , A61M5/14244 , A61M25/0043 , A61M25/005 , A61M25/0067 , A61M25/0069 , A61M25/02 , A61M39/0247 , A61M39/10 , A61M39/26 , A61M2025/028 , A61M2039/025 , A61M2039/0261 , A61M2039/027 , A61M2039/0279 , A61M2039/1027 , A61M2039/1072 , A61M2210/0687 , A61N1/0539 , F16L37/22 , Y10S604/905
摘要： A catheter for use with a medical infusion or other fluid system. The catheter may include a flexible elongate tubular core that is resistant to radial collapse, and a separate tubular tip member forming the catheter distal tip. The catheter may further include a flexible, e.g., elastomeric, jacket that surrounds at least a portion of the tubular core. The jacket may have a radial compliance that is greater than that of the tubular core. The jacket may further define an outer diameter that is about 4 to about 6 times greater than an outer diameter of the core.
摘要翻译： 用于与医用输液器或其他流体系统一起使用的导管。 导管可以包括抵抗径向塌陷的柔性细长管状芯，以及形成导管远端尖端的单独的管状尖端构件。 导管还可以包括围绕管状芯的至少一部分的柔性例如弹性的护套。 护套可具有大于管状芯的径向顺应性。 护套还可以限定外径比芯的外径大约4至大约6倍。
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公开(公告)号：US20110215116A1
公开(公告)日：2011-09-08
申请号：US13042082
申请日：2011-03-07
申请人： Kevin S. Fuller , James G. Skakoon
发明人： Kevin S. Fuller , James G. Skakoon
CPC分类号： B29C45/14 , A47G19/24 , B23P19/00 , B29C45/14754 , B29L2031/565 , B65D47/0847 , B65D51/24 , B65D83/06 , Y10T29/49826
摘要： A container for dispensing food products can include a clump decimator portion for breaking up food clumps. In one embodiment, a container comprises a container portion having an open interior and an open top and a cover for selectively covering the open top. The cover can include a cover base portion and a rotatable top portion configured to be coupled on top of the base portion. The cover base portion can include a plurality of dispensing apertures for allowing a food product to be dispensed therethrough. The rotatable top portion can be selectively rotatable relative to the cover base portion and the container portion. The clump decimator portion can extend downwardly and radially from the top portion through the cover base portion and into the container portion. The clump decimator can rotate as the rotatable top portion is rotated to agitate the contents of the container portion while they are being dispensed.
摘要翻译： 用于分配食品的容器可以包括用于分解食物块的团块抽取器部分。 在一个实施例中，容器包括具有开放内部和开放顶部的容器部分和用于选择性地覆盖开放顶部的盖子。 盖可以包括盖基部和可配置为联接在基部的顶部上的可旋转顶部。 盖基部分可以包括多个分配孔，用于允许食品通过其分配。 可旋转顶部可以相对于盖基部和容器部分选择性地旋转。 该团块抽取器部分可以从顶部向下并径向延伸穿过盖底部并进入容器部分。 当可旋转顶部旋转时，聚集抽吸器可以旋转，以在容器部分被分配时搅拌容器部分的内容物。
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公开(公告)号：US20100162552A1
公开(公告)日：2010-07-01
申请号：US12721307
申请日：2010-03-10
IPC分类号： B23P11/00
CPC分类号： A61B90/11 , A61B34/20 , A61B2017/603 , A61B2090/062 , Y10T29/49826
摘要： An alignment device and method is provided. Higher precision is achieved when fixing an orientation of an insertion axis using alignment devices shown. A symmetric clamping force is provided that reduces or eliminates unwanted displacement after the desired orientation is obtained. Another feature includes increased flexibility to use a variety of primary medical devices. Another feature includes a standoff feature that reduces tissue damage. Another feature includes an orienting fixture for image guided procedures.
摘要翻译： 提供了一种对准装置和方法。 使用所示的对准装置固定插入轴的取向时可获得更高的精度。 提供对称的夹紧力，其在获得期望的取向之后减少或消除不期望的位移。 另一个特征包括增加使用各种主要医疗设备的灵活性。 另一个特征包括减少组织损伤的间隔特征。 另一个特征包括用于图像引导过程的定向夹具。
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8.发明申请Dry Powder Inhalers with Dual Piercing Members and Related Devices and Methods 有权具有双穿孔成员和相关设备和方法的干粉吸入器公开(公告)号：US20100078021A1
公开(公告)日：2010-04-01
申请号：US12566724
申请日：2009-09-25
IPC分类号： A61M15/00
CPC分类号： A61M15/0041 , A61M15/0021 , A61M15/0026 , A61M15/0033 , A61M15/0035 , A61M15/0045 , A61M15/0048 , A61M15/0075 , A61M2202/064
摘要： A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.
摘要翻译： 干粉吸入器包括具有剂量容器盘的剂量容器组件，其具有相对的上表面和下表面，在第一半径处具有第一排周向间隔开的剂量容器，在第二半径处具有第二排周向间隔开的剂量容器。 剂量容器在其中具有干粉，并通过第一柔性密封剂在上表面的孔上密封，并且在下表面上的孔上密封第二柔性密封剂。 穿刺机构包括两个在剂量容器盘中的两排剂量容器之间连续交替的往复式穿孔器。 可旋转的斜盘包括交错的同心关系的第一组和第二组周向间隔开的斜面元件，其被构造成在缩回位置和延伸位置之间移动第一和第二穿孔构件。
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公开(公告)号：US07660621B2
公开(公告)日：2010-02-09
申请号：US09827266
申请日：2001-04-05
IPC分类号： A61F11/00
CPC分类号： A61N1/0539 , A61B34/20 , A61B90/11 , A61B2017/0023 , A61B2017/00398 , A61B2017/00911 , A61B2017/3407 , A61B2017/3409 , A61B2017/3411 , A61B2017/347 , A61B2034/2051 , A61B2034/2055 , A61B2090/103 , A61B2090/363 , A61B2090/374 , A61B2090/3762 , A61B2090/3983 , A61N1/0534
摘要： An introducer is described that is coupled to a patient, specifically a patient's skull. The introducer may include an advancer that is remote from the patient, the advancer communicating with the introducer by means of a cable system. The introducer may also include a local position sensor that indicates the position of the primary medical device being introduced. The introducer may also include a frameless reference system that locates the primary medical device relative to a table that the patient is fixed to.
摘要翻译： 描述了与患者，特别是患者的头骨联接的导引器。 导引器可以包括远离患者的推进器，推进器借助于电缆系统与引入器通信。 导引器还可以包括指示被引入的主要医疗装置的位置的局部位置传感器。 导引器还可以包括无框架参考系统，其定位主要医疗装置相对于患者被固定到的桌子。
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公开(公告)号：US20090118743A1
公开(公告)日：2009-05-07
申请号：US12349657
申请日：2009-01-07
IPC分类号： A61B19/00
摘要： This documents describes among other things a normalizing stage apparatus, tools and methods. One example includes a base that defines a trajectory. A first stage is moveably coupled to the base and the first stage moves along the trajectory. A second stage is moveably coupled to the first stage and moves an instrument coupled thereto with respect to the base and the first stage. Before movement of the instrument, the first and second stages are in first positions desired (e.g. predetermined) distances from a target area in the body. Another example includes the first stage and a guide tube stop coupled with the first stage. A guide tube is coupled with the guide tube stop and extends through a guide tube stop lumen. The guide tubes outer perimeter is dimensioned and configured to snugly couple with the surface defining the guide tube stop lumen.
摘要翻译： 本文件描述了归一化阶段装置，工具和方法。 一个例子包括定义轨迹的基座。 第一阶段可移动地联接到基座，并且第一阶段沿轨迹移动。 第二阶段可移动地联接到第一阶段并且移动相对于基座和第一平台耦合到其上的仪器。 在仪器移动之前，第一和第二阶段处于从身体中的目标区域所需的（例如预定的）距离的第一位置。 另一个例子包括第一阶段和与第一阶段联接的导管停止。 引导管与引导管止动件连接并延伸穿过导管止动腔。 引导管外周的尺寸和构造使其与限定引导管止血腔的表面紧密耦合。
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