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    Apparatus and method for accessing biopsy site
    5.
    发明授权
    Apparatus and method for accessing biopsy site 有权
    用于进入活检部位的装置和方法

    公开(公告)号：US06471700B1

    公开(公告)日：2002-10-29

    申请号：US09477255

    申请日：2000-01-04

    申请人： Fred Burbank ,  William C. Homet ,  Paul Lubock ,  Richard L. Quick ,  Martin Shabaz

    发明人： Fred Burbank ,  William C. Homet ,  Paul Lubock ,  Richard L. Quick ,  Martin Shabaz

    IPC分类号： A61B1818

    CPC分类号： A61B10/0266 ,  A61B10/02 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1482 ,  A61B18/1487 ,  A61B90/37 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/006 ,  A61M37/0069

    摘要： A system for accessing a desired site within a patient's body includes a cannula defining an inner lumen that opens into a longitudinally extending side aperture formed in the side of the cannula, near its distal end. An electrosurgical stylet slidably fits inside the inner lumen. At the distal end of the stylet is an electrosurgical electrode capable of ablating tissue and permitting advancement of the system into a patient's body. The electrode, in an expanded deployed configuration, can be wider than the maximum transverse dimension of the cannula, but it may be deflected toward the center of the stylet so that the electrode fits within the inner lumen of the cannula, permitting the stylet to be inserted and removed through the cannula. An elongate guide tube having a central axial bore which communicates with an orifice in the side of the guide tube can be inserted into the inner lumen of the cannula such that the guide tube orifice coincides with the longitudinally extending side aperature of the cannula. In use, the stylet with the cannula disposed about it is advanced into the patient's tissue, using electrosurgical ablation, until the side aperture of the cannula is disposed adjacent a desired site within the patient. The stylet can then be withdrawn from the cannula providing access through the inner lumen of the cannula to the tissue at the desired site.

    摘要翻译： 用于进入患者体内的期望部位的系统包括套管，该套管限定形成在套管一侧的纵向延伸的侧孔的靠近其远端的内腔。 电外科手术针可滑动地装配在内腔内。 在探针的远端是能够消融组织并允许系统进入患者体内的电外科电极。 处于扩展展开构造的电极可以比插管的最大横向尺寸宽，但是其可以朝着探针的中心偏转，使得电极配合在套管的内腔内，从而允许探针为 通过插管插入和移除。 具有与引导管侧面的孔连通的中心轴向孔的细长引导管可以插入插管的内腔中，使得引导管孔与插管的纵向延伸的侧面温度重合。 在使用中，具有围绕其设置的插管的探针被推进到患者的组织中，使用电外科手术切除，直到套管的侧孔邻近患者内的期望部位设置。 然后可以从插管中取出探针，提供通过插管的内腔进入所需部位的组织的通路。

    Tissue site markers for in vivo imaging
    8.
    发明授权
    Tissue site markers for in vivo imaging 有权
    用于体内成像的组织位点标记

    公开(公告)号：US08224424B2

    公开(公告)日：2012-07-17

    申请号：US12460052

    申请日：2009-07-13

    申请人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    发明人： Fred H. Burbank ,  Paul Lubock ,  Michael L. Jones ,  Richard L. Quick ,  Frank Louw ,  Stephen A. De Santis

    IPC分类号： A61B5/00 ,  A61B6/00 ,  A61B19/00

    CPC分类号： A61M37/0069 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61K49/006 ,  A61K49/222

    摘要： The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging. The biopsy site marker may be accurately fixed to the biopsy site so as to resist migration from the biopsy cavity when a placement instrument is withdrawn, and when the marked tissue is subsequently moved or manipulated.

    摘要翻译： 本发明涉及活检部位标记和标记活组织检查部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区别开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。 可以将活检部位标记物精确地固定到活检部位，以便当放置放置器械被取出时以及随后标记的组织被移动或操纵时抵抗从活检腔的迁移。