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1.发明申请公开(公告)号：US20150166956A1
公开(公告)日：2015-06-18
申请号：US14167393
申请日：2014-01-29
Applicant: General Electric Company
Inventor： Christopher Michael Puleo , Erik Leeming Kvam , Gregory Andrew Grossmann , Craig Patrick Galligan , Jason Michael Nichols , Xuefeng Wang , Jason Louis Davis
IPC: C12N5/078
CPC classification number: B01D21/0087 , B01D17/02 , B01D21/0006 , B01D21/0042 , B01D21/02 , B01D21/10 , B01D21/2433 , B01D21/2444 , B01D21/245 , B01D2221/04 , B01L3/502753 , B01L3/502761 , B01L2200/0631 , B01L2200/0652 , B01L2200/0668 , B01L2300/0681 , B01L2300/0851 , B01L2400/0421 , B01L2400/043 , B01L2400/0457 , B01L2400/0469 , C02F1/00 , C02F1/24 , C02F1/444 , C02F1/48 , C02F2001/007 , C02F2101/32 , C02F2103/08 , C02F2103/10 , C02F2201/002 , C12M47/02 , C12N5/0641
Abstract: A device is configured for separation of particulates dispersed within a base fluid, wherein the particulates have a relative density difference compared to the base fluid. The device comprises a microchannel of length l and height h comprising an inlet and an outlet; a microporous surface on one or more walls of the microchannel; a collection chamber on an opposing side of the microporous surface; and an applied force field across the height h of the microchannel to sediment the particles through the microporous surface into the collection chamber. The microporous body operationally generates a fluid flow regime comprising a first fluid flow having a first flow rate through the microchannel and a second fluid flow having a second flow rate through the collection chamber and the second flow rate is a fraction of the first flow rate.
Abstract translation: 一种装置被配置用于分离分散在基础流体中的微粒，其中所述颗粒与基础流体相比具有相对密度差。 该装置包括长度为l的微通道和包括入口和出口的高度h; 在微通道的一个或多个壁上的微孔表面; 在微孔表面的相对侧上的收集室; 以及穿过微通道的高度h的施加的力场，以将颗粒通过微孔表面沉淀到收集室中。 微孔体可操作地产生流体流动状态，其包括具有通过微通道的第一流量的第一流体流和具有通过收集室的第二流速的第二流体流，第二流量是第一流量的一部分。
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公开(公告)号：US20160146802A1
公开(公告)日：2016-05-26
申请号：US14548383
申请日：2014-11-20
Applicant: General Electric Company
Inventor： Bing Li , Brian Christopher Bales , David Roger Moore , Jason Michael Nichols , Cathryn Ellen Olsen , William Christopher Alberts , Frank John Mondello
IPC: G01N33/543 , G01N33/548 , G01N33/558
CPC classification number: G01N33/54386 , G01N33/54353 , G01N33/548 , G01N33/558
Abstract: A device comprising a modified porous membrane is provided. The modified porous membrane comprises a polymer coating grafted to a porous membrane. The device is used for analyte detection from a biological sample using an immunoassay. The device comprises a sample application zone at one end of the device for applying a biological sample comprising a target analyte; and a detection zone present at another end of the device, downstream of the sample application zone for detecting the target analyte, wherein the detection zone comprises one or more first biomolecules immobilized on a modified porous membrane having a structure of Formula (I).
Abstract translation: 提供了包含改性多孔膜的装置。 改性多孔膜包括接枝到多孔膜上的聚合物涂层。 该装置用于使用免疫测定从生物样品进行分析物检测。 该装置包括用于施加包含目标分析物的生物样品的装置的一端处的样品施加区域; 以及位于所述装置的另一端的检测区，其位于所述样品施加区的下游，用于检测所述目标分析物，其中所述检测区包含固定在具有式（I）的结构的改性多孔膜上的一个或多个第一生物分子。
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公开(公告)号：US20150265977A1
公开(公告)日：2015-09-24
申请号：US14221892
申请日：2014-03-21
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Louisa Ruth Carr , Hongchen Dong , Paul Michael Smigelski, JR. , Jason Louis Davis , Jason Michael Nichols
CPC classification number: B01D71/70 , B01D67/0088 , B01D69/10 , B01D69/12 , B01D71/36 , B01D2323/26 , B01D2323/30 , C02F1/444 , C02F2101/32
Abstract: Methods for treating water containing dissolved solids, suspended solids, organic material, or combinations include contacting the water with a coated membrane comprising a coating material disposed on a membrane substrate, the coating material comprising structural units derived from a compound of formula I, a compound of formula II and a compound of formula III; wherein R1, R2, and R3 are, independently at each occurrence, C1-C12 alkyl; R4 is alkylsilyl; L1 is alkylurethanyl; L2 and L3 are, independently at each occurrence, alkyl; X is hydroxy, alkoxy, or alkylamino; and m, n, and p, independently at each occurrence, range between 4 and 9. The coated membrane is joined to a backing in membrane filtration apparatuses for use in the methods.
Abstract translation: 用于处理含有溶解的固体，悬浮固体，有机材料或组合的水的方法包括使水与包含设置在膜基材上的涂料的涂布膜接触，所述涂料包含衍生自式I化合物的结构单元，化合物 的式II化合物和式III化合物; 其中R 1，R 2和R 3在每次出现时独立地为C 1 -C 12烷基; R4是烷基甲硅烷基; L1是烷基氨基甲酸酯; L2和L3各自独立地为烷基; X是羟基，烷氧基或烷基氨基; m，n和p各自独立地在4和9之间。涂覆的膜与用于该方法的膜过滤装置中的背衬接合。
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Patent Agency Ranking
公开(公告)号：US20150246327A1
公开(公告)日：2015-09-03
申请号：US14194340
申请日：2014-02-28
Applicant: General Electric Company
Inventor： Jason Michael Nichols , Matthew Jeremiah Misner , Hongyi Zhou
CPC classification number: B01D69/12 , B01D67/00 , B01D69/02 , B01D69/06 , B01D71/12 , B01D2325/08 , B29C39/003 , B29C39/026 , B29C39/44 , B29C67/0048 , B29K2001/18 , B29K2105/04 , B29L2031/755 , G03F7/0002 , G05B15/02
Abstract: A porous membrane patterning technique is provided. In one embodiment, a porous membrane may be patterned via printing on the porous membrane with a solvent such that the porous membrane collapses where the solvent is applied. In another embodiment, a patterned porous membrane may be formed by casting a solution including at least components of the porous membrane into voids of a casting plate or stencil, removing the casting plate, and letting the remaining components go through a phase inversion process to form porous membrane regions.
Abstract translation: 提供多孔膜图案化技术。 在一个实施方案中，多孔膜可以通过在多孔膜上印刷而用溶剂进行图案化，使得多孔膜在施加溶剂的地方崩溃。 在另一个实施方案中，图案化的多孔膜可以通过将至少包括多孔膜的组分的溶液浇铸到流延板或模板的空隙中，去除流延板，并使剩余的组分经历相转化过程形成 多孔膜区域。
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公开(公告)号：US20150165347A1
公开(公告)日：2015-06-18
申请号：US14563334
申请日：2014-12-08
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Jason Michael Nichols , Christopher Michael Puleo , Jason Louis Davis , Daniel George Norton , Craig Patrick Galligan , Rachel Marie Gettings
CPC classification number: B01D21/0087 , B01D17/02 , B01D21/0006 , B01D21/0042 , B01D21/02 , B01D21/10 , B01D21/2433 , B01D21/2444 , B01D21/245 , B01D2221/04 , B01L3/502753 , B01L3/502761 , B01L2200/0631 , B01L2200/0652 , B01L2200/0668 , B01L2300/0681 , B01L2300/0851 , B01L2400/0421 , B01L2400/043 , B01L2400/0457 , B01L2400/0469 , C02F1/00 , C02F1/24 , C02F1/444 , C02F1/48 , C02F2001/007 , C02F2101/32 , C02F2103/08 , C02F2103/10 , C02F2201/002 , C12M47/02 , C12N5/0641
Abstract: A microclarification system is disclosed which can be used to separate solid particulates dispersed within a base fluid such as water. The microclarification system includes a plurality of microfluidic separator units disposed between and in fluid communication with a fluid inlet manifold and a fluid outlet manifold. The microclarification system enforces lamellar flow of fluid though it and as a result the rate at which particles settle is enhanced within a collection chamber associated with each microfluidic separator unit and through which the fluid being purified must pass. Each microfluidic separator unit includes a microfluidic outlet microchannel disposed between the microfluidic collection chamber and the fluid outlet manifold, and a gas-liquid flushing module configured to purge particulates from the collection chamber during a collection chamber purge cycle. Optionally, each microfluidic separator unit may include a microfluidic inlet microchannel. The system holds promise in municipal water purification among other applications.
Abstract translation: 公开了一种微分离系统，其可用于分离分散在基础流体例如水中的固体颗粒。 微型澄清系统包括多个微流体分离器单元，其设置在流体入口歧管和流体出口歧管之间并与其流体连通。 微量澄清系统执行流体的层状流动，结果，在与每个微流体分离器单元相关联的收集室内增强颗粒沉降的速率，并且净化的流体必须通过该速率。 每个微流体分离器单元包括设置在微流体收集室和流体出口歧管之间的微流体出口微通道，以及构造成在收集室清洗循环期间从收集室中清除微粒的气液冲洗模块。 任选地，每个微流体分离器单元可以包括微流体入口微通道。 该系统在城市净水中的应用前景广阔。
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公开(公告)号：US20170050154A1
公开(公告)日：2017-02-23
申请号：US15342370
申请日：2016-11-03
Applicant: General Electric Company
Inventor： Louisa Ruth Carr , Paul Michael Smigelski, JR. , Jason Michael Nichols , James Manio Silva
IPC: B01D71/76 , B01D61/14 , C08J7/04 , C08F220/38 , C09D133/14 , C08J9/36 , C02F1/44 , B01D71/40
Abstract: Provided herein are copolymers and copolymer compositions that are both hydrophilic and oleophobic. The copolymers include structural units derived from a fluoroalkyl monomer and a zwitterionic monomer. It further relates to membranes formed by coating a porous substrate with the copolymeric compositions. The copolymeric coating imparts hydrophilicity and oleophobicity/oil-tolerance to the membranes. The uses of such membranes as microfiltration membrane or ultrafiltration membrane are also provided.
Abstract translation: 本文提供了亲水和疏油的共聚物和共聚物组合物。 共聚物包括衍生自氟烷基单体和两性离子单体的结构单元。 它还涉及通过用共聚物组合物涂覆多孔基材而形成的膜。 共聚物涂层对膜具有亲水性和疏油性/耐油性。 还提供了这种膜的使用，如微滤膜或超滤膜。
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公开(公告)号：US09415349B2
公开(公告)日：2016-08-16
申请号：US14194340
申请日：2014-02-28
Applicant: General Electric Company
Inventor： Jason Michael Nichols , Matthew Jeremiah Misner , Hongyi Zhou
IPC: B05D3/00 , B05D3/04 , B29C37/02 , B01D39/00 , B01D69/12 , B01D67/00 , B29C39/00 , B29C39/02 , B29C39/44 , B29C67/00 , G05B15/02 , G03F7/00 , B01D69/02 , B01D69/06 , B01D71/12 , B29K1/00 , B29K105/04 , B29L31/00
CPC classification number: B01D69/12 , B01D67/00 , B01D69/02 , B01D69/06 , B01D71/12 , B01D2325/08 , B29C39/003 , B29C39/026 , B29C39/44 , B29C67/0048 , B29K2001/18 , B29K2105/04 , B29L2031/755 , G03F7/0002 , G05B15/02
Abstract: A porous membrane patterning technique is provided. In one embodiment, a porous membrane may be patterned via printing on the porous membrane with a solvent such that the porous membrane collapses where the solvent is applied. In another embodiment, a patterned porous membrane may be formed by casting a solution including at least components of the porous membrane into voids of a casting plate or stencil, removing the casting plate, and letting the remaining components go through a phase inversion process to form porous membrane regions.
Abstract translation: 提供多孔膜图案化技术。 在一个实施方案中，多孔膜可以通过在多孔膜上印刷而用溶剂进行图案化，使得多孔膜在施加溶剂的地方崩溃。 在另一个实施方案中，图案化的多孔膜可以通过将至少包括多孔膜的组分的溶液浇铸到流延板或模板的空隙中，去除流延板，并使剩余的组分经过相转化过程形成 多孔膜区域。
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公开(公告)号：US20160146795A1
公开(公告)日：2016-05-26
申请号：US14548338
申请日：2014-11-20
Applicant: General Electric Company
Inventor： Bing Li , Brian Christopher Bales , David Roger Moore , Jason Michael Nichols , Cathryn Ellen Olsen , William Christopher Alberts , Frank John Mondello
IPC: G01N33/548
CPC classification number: G01N33/548 , B01D67/009 , B01D69/144 , B01D71/78 , G01N33/54353 , Y02A50/57
Abstract: A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. A method for analyte detection from a biological sample using an immunoassay is also provided using the modified membrane, wherein the method comprises a) providing a modified porous membrane having the structure of Formula (I), b) incubating the modified porous membrane with a first biomolecule, wherein the first biomolecule binds to the modified porous membrane to form a first biomolecule bound modified porous membrane; and c) adding a biological sample comprising at least an analyte to the first biomolecule bound modified porous membrane for analyte detection by binding the analyte to the first biomolecule bound to the modified porous membrane.
Abstract translation: 描述了包含接枝到多孔膜上的聚合物涂层的改性多孔膜。 还提供了使用免疫测定法从生物样品中分析物检测的方法，其中所述方法包括：a）提供具有式（I）结构的改性多孔膜，b）将所述改性多孔膜与第一 生物分子，其中所述第一生物分子与修饰的多孔膜结合以形成第一生物分子结合的改性多孔膜; 和c）将包含至少一种分析物的生物样品添加到第一生物分子结合的改性多孔膜上，以通过将分析物结合到与修饰的多孔膜结合的第一生物分子来进行分析物检测。
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