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公开(公告)号：US10131868B2
公开(公告)日：2018-11-20
申请号：US15376259
申请日：2016-12-12
Applicant: General Electric Company
Inventor： Younkoo Jeong , Weston Blaine Griffin , Vandana Keskar , Zhipeng Zhang
Abstract: A bioreactor is provided. The bioreactor is a multi-scalable bioreactor, which comprises a culture vessel for seeding and culturing cells by adding a cell-culture media, wherein the culture vessel comprises at least a side wall and a bottom surface, a specific heat transfer area and a specific gas transfer area; wherein the culture vessel is configured to accommodate the cell-culture media volume up to 10 liters, and wherein the specific heat transfer area and the specific gas transfer area are independent of cell-culture media volume. A kit for culturing cells in a large scale is also provided which further comprises disposable tubings, culture bag or combinations thereof. A method for culturing cells is also provided.
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公开(公告)号：US09949719B2
公开(公告)日：2018-04-24
申请号：US14572416
申请日：2014-12-16
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Zhipeng Zhang , Cynthia Elizabeth Landberg Davis , Weston Blaine Griffin , Ying Mao
CPC classification number: A61B8/4416 , A61B6/025 , A61B6/0414 , A61B6/4417 , A61B6/502 , A61B8/0825 , A61B8/14 , A61B8/403 , A61B8/4209 , A61B8/4281 , A61B8/429 , A61B8/4461 , A61B8/54
Abstract: An ultrasound scan probe and support mechanism are provided for use in a multi-modality mammography imaging system, such as a combined tomosynthesis and ultrasound imaging system. In one embodiment, the ultrasound components may be positioned and configured so as not to interfere with the tomosynthesis imaging operation, such as to remain out of the X-ray beam path. Further, the ultrasound probe and associated components may be configured to as to move and scan the breast tissue under compression, such as under the compression provided by one or more paddles used in the tomosynthesis imaging operation.
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公开(公告)号：US20160177666A1
公开(公告)日：2016-06-23
申请号：US14574717
申请日：2014-12-18
Applicant: General Electric Company
CPC classification number: E21B34/08 , E21B43/121 , E21B43/32 , F16K31/122 , F16K31/26 , F16K33/00 , F16K37/005
Abstract: A flow control system is provided for a horizontal well production system having a casing, a tube having an intake opening and disposed within the casing, and a gap formed between the casing and the tube. The flow control system includes a valve having an orifice, coupled to the tube and disposed proximate to the intake opening. The flow control system further includes an actuator coupled to the valve and configured to open the valve in response to a presence of a liquid in the gap, proximate to the intake opening, to permit flow of the liquid into the tube via the intake opening, and to close the valve in response to a presence of a gas in the gap, proximate to the intake opening, to prevent flow of the gas into the tube via the intake opening.
Abstract translation: 为水平井生产系统提供流量控制系统，该系统具有壳体，具有进气开口并设置在壳体内的管以及在壳体和管之间形成的间隙。 流量控制系统包括具有孔的阀，其连接到管并且靠近进气开口设置。 流量控制系统还包括致动器，其联接到阀并且被配置为响应于间隙中存在液体而靠近进气开口打开阀，以允许液体经由进气口流入管中， 并且响应于间隙中存在的气体，靠近进气口而关闭阀，以防止气体经由进气口流入管中。
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公开(公告)号：US09855014B2
公开(公告)日：2018-01-02
申请号：US14572452
申请日：2014-12-16
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Cynthia Elizabeth Landberg Davis , Zhipeng Zhang , Weston Blaine Griffin , Ying Mao
CPC classification number: A61B6/0414 , A61B6/025 , A61B6/4417 , A61B6/502 , A61B8/4281 , A61B8/4416
Abstract: The present disclosure relates to the manufacture and use of a non-rigid breast compression paddle, such as a compression paddle having a mesh material forming the primary interface with patient tissue. In certain implementations, an automatic feedback driven approach may be used in conjunction with such a compression paddle for compressing breast tissue.
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公开(公告)号：US20170088810A1
公开(公告)日：2017-03-30
申请号：US15376259
申请日：2016-12-12
Applicant: General Electric Company
Inventor： Younkoo Jeong , Weston Blaine Griffin , Vandana Keskar , Zhipeng Zhang
CPC classification number: C12M41/14 , C12M23/02 , C12M23/24 , C12M29/00 , C12M41/22 , C12M41/26 , C12M41/34
Abstract: A bioreactor is provided. The bioreactor is a multi-scalable bioreactor, which comprises a culture vessel for seeding and culturing cells by adding a cell-culture media, wherein the culture vessel comprises at least a side wall and a bottom surface, a specific heat transfer area and a specific gas transfer area; wherein the culture vessel is configured to accommodate the cell-culture media volume upto 10 liters, and wherein the specific heat transfer area and the specific gas transfer area are independent of cell-culture media volume. A kit for culturing cells in a large scale is also provided which further comprises disposable tubings, culture bag or combinations thereof. A method for culturing cells is also provided.
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Patent Agency Ranking
公开(公告)号：US09587215B2
公开(公告)日：2017-03-07
申请号：US14453683
申请日：2014-08-07
Applicant: General Electric Company
Inventor： Ying Mao , Kenneth Roger Conway , Weston Blaine Griffin , Reginald Donovan Smith , Evelina Roxana Loghin , Vandana Keskar , Chengkun Zhang , Zhipeng Zhang
CPC classification number: C12M33/00 , A01N1/0236 , A01N1/0268 , B01L7/00 , B01L2300/1827 , C12M1/26 , C12M33/04 , C12M41/12 , C12M45/20 , C12M45/22
Abstract: A coupling device configured to form a sample access assembly is provided. The sample access assembly is configured to house a sample. The coupling device includes a heating component and a separating component. Further, the separating component is configured to separate portions of first and second containers that form first and second compartments of the sample access assembly. Moreover, the heating component is configured to heat at least a portion of the sample.
Abstract translation: 提供了构造成形成样品存取组件的联接装置。 样品存取组件被配置为容纳样品。 联接装置包括加热部件和分离部件。 此外，分离部件构造成分离形成样品进入组件的第一和第二隔室的第一和第二容器的部分。 此外，加热部件构造成加热样品的至少一部分。
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公开(公告)号：US20160166217A1
公开(公告)日：2016-06-16
申请号：US14572452
申请日：2014-12-16
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Cynthia Elizabeth Landberg Davis , Zhipeng Zhang , Weston Blaine Griffin , Ying Mao
CPC classification number: A61B6/0414 , A61B6/025 , A61B6/4417 , A61B6/502 , A61B8/4281 , A61B8/4416
Abstract: The present disclosure relates to the manufacture and use of a non-rigid breast compression paddle, such as a compression paddle having a mesh material forming the primary interface with patient tissue. In certain implementations, an automatic feedback driven approach may be used in conjunction with such a compression paddle for compressing breast tissue.
Abstract translation: 本公开涉及非刚性乳房压缩桨的制造和使用，例如具有形成与患者组织的主要界面的网状材料的压缩桨。 在某些实施方案中，自动反馈驱动方法可以与这种用于压缩乳房组织的压缩桨一起使用。
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公开(公告)号：US20160090568A1
公开(公告)日：2016-03-31
申请号：US14499709
申请日：2014-09-29
Applicant: General Electric Company
Inventor： Younkoo Jeong , Weston Blaine Griffin , Vandana Keskar , Zhipeng Zhang
CPC classification number: C12M41/14 , C12M23/02 , C12M23/24 , C12M29/00 , C12M41/22 , C12M41/26 , C12M41/34
Abstract: A bioreactor is provided. The bioreactor is a multi-scalable bioreactor, which comprises a culture vessel for seeding and culturing cells by adding a cell-culture media, wherein the culture vessel comprises at least a side wall and a bottom surface, a specific heat transfer area and a specific gas transfer area; wherein the culture vessel is configured to accommodate the cell-culture media volume up to 10 liters, and wherein the specific heat transfer area and the specific gas transfer area are independent of cell-culture media volume. A kit for culturing cells in a large scale is also provided which further comprises disposable tubings, culture bag or combinations thereof. A method for culturing cells is also provided.
Abstract translation: 提供生物反应器。 生物反应器是一种多重扩张的生物反应器，其包括用于通过添加细胞培养基播种和培养细胞的培养容器，其中培养容器至少包括侧壁和底表面，比热传递面积和特定的 气体转移区; 其中所述培养容器被配置为容纳高达10升的细胞培养基体积，并且其中所述比热传递面积和所述特定气体传递区域与细胞培养基体积无关。 还提供了用于大规模培养细胞的试剂盒，其还包括一次性管，培养袋或其组合。 还提供培养细胞的方法。
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公开(公告)号：US20160053296A1
公开(公告)日：2016-02-25
申请号：US14462594
申请日：2014-08-19
Applicant: General Electric Company
Inventor： Chengkun Zhang , Kenneth Roger Conway , Donald Joseph Buckley , Eugene Pauling Boden , Weston Blaine Griffin , Anshika Bajaj , Reginald Donovan Smith , Zhipeng Zhang
Abstract: A sampling assembly configured to be coupled to a sample source is provided. The sampling assembly is configured to facilitate aseptic sampling at one or more instances in time. The sampling assembly includes a first conduit having a first port and a second port, where the first port is configured to be coupled to the sample source, and where the second port is configured to be hermetically sealed. The sampling assembly further includes a plurality of sub-conduits having corresponding sub-ports, where each of the plurality of sub-conduits is operatively coupled to the first conduit at respective connection points, and where each of the sub-ports is in fluidic communication with the first conduit. Moreover, the sampling assembly includes a plurality of sampling kits, where each sampling kit of the plurality of sampling kits is operatively connected to a respective sub-port of a corresponding sub-conduit.
Abstract translation: 提供了一种被配置为耦合到采样源的采样组件。 采样组件被配置为便于在一个或多个实例的时间进行无菌取样。 采样组件包括具有第一端口和第二端口的第一导管，其中第一端口被配置为耦合到采样源，并且其中第二端口被配置为气密密封。 采样组件还包括具有对应子端口的多个子导管，其中多个子导管中的每一个在相应的连接点处可操作地耦合到第一导管，并且其中每个子端口处于流体连通 与第一个导管。 此外，采样组件包括多个采样套件，其中多个采样套件的每个采样套件可操作地连接到相应副导管的相应子端口。
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公开(公告)号：US09550972B2
公开(公告)日：2017-01-24
申请号：US14499709
申请日：2014-09-29
Applicant: General Electric Company
Inventor： Younkoo Jeong , Weston Blaine Griffin , Vandana Keskar , Zhipeng Zhang
CPC classification number: C12M41/14 , C12M23/02 , C12M23/24 , C12M29/00 , C12M41/22 , C12M41/26 , C12M41/34
Abstract: A bioreactor is provided. The bioreactor is a multi-scalable bioreactor, which comprises a culture vessel for seeding and culturing cells by adding a cell-culture media, wherein the culture vessel comprises at least a side wall and a bottom surface, a specific heat transfer area and a specific gas transfer area; wherein the culture vessel is configured to accommodate the cell-culture media volume up to 10 liters, and wherein the specific heat transfer area and the specific gas transfer area are independent of cell-culture media volume. A kit for culturing cells in a large scale is also provided which further comprises disposable tubings, culture bag or combinations thereof. A method for culturing cells is also provided.
Abstract translation: 提供生物反应器。 生物反应器是一种多重扩张的生物反应器，其包括用于通过添加细胞培养基播种和培养细胞的培养容器，其中培养容器至少包括侧壁和底表面，比热传递面积和特定的 气体转移区; 其中所述培养容器被配置为容纳高达10升的细胞培养基体积，并且其中所述比热传递面积和所述特定气体传递区域与细胞培养基体积无关。 还提供了用于大规模培养细胞的试剂盒，其还包括一次性管，培养袋或其组合。 还提供培养细胞的方法。
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