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    FLUIDIC BRIDGE DEVICE AND SAMPLE PROCESSING METHODS
    1.
    发明公开
    FLUIDIC BRIDGE DEVICE AND SAMPLE PROCESSING METHODS 审中-公开

    公开(公告)号：US20240353439A1

    公开(公告)日：2024-10-24

    申请号：US18435755

    申请日：2024-02-07

    Applicant: Cepheid

    Inventor： Douglas B. Dority

    IPC: G01N35/10 ,  B01L3/00 ,  G01N35/00

    CPC classification number: G01N35/1095 ,  B01L3/502 ,  B01L3/502715 ,  B01L3/561 ,  B01L3/563 ,  G01N35/10 ,  B01L2200/026 ,  G01N2035/00326

    Abstract: A fluidic bridge device for transport of a fluid sample between a first sample processing device and a second sample processing device. The fluidic bridge may include one or more fluid channels extending between fluid-tight couplings attachable to transfer ports of the first and second sample processing device. In one aspect, the first device is a sample preparation device and the second device is an assay device. The fluidic bridge can include at least two fluid conduits, at least one for transport of the prepared sample, and at least one other to facilitate displacement of air to allow flow of the prepared sample through the other fluid conduit. The fluid channels can include one or more of an amplification chamber, a processing chamber, a gas-permeable vent, a bubble trap, a filter, and an external port. Methods of preparing and transporting a fluid sample between devices are provided herein.

    Dual balance electrodynamic trap with enhanced safety and modularity
    2.
    发明授权
    Dual balance electrodynamic trap with enhanced safety and modularity 有权

    公开(公告)号：US11998916B2

    公开(公告)日：2024-06-04

    申请号：US18136829

    申请日：2023-04-19

    Applicant: Microlev LLC

    Inventor： Josefina Hajek-Herrera ,  David Woolley ,  Ryan Davis

    IPC: B01L3/00

    CPC classification number: B01L3/502784 ,  B01L3/561 ,  B01L2200/0626 ,  B01L2400/0415

    Abstract: A dual balance electrode trap having an outer chamber, a droplet dispenser holder removably coupled to the top surface of the outer chamber, and a rod holder having a central opening and four peripheral openings that are sized and shaped to allow four respective quadrupole metal rods to pass therethrough. The droplet dispenser holder has a top surface, a bottom surface, and a through hole that extends from the dispenser holder top surface to the droplet dispenser bottom surface. The through hole has a larger diameter portion adjacent to the top surface and a smaller diameter portion adjacent to the bottom surface, thereby preventing a droplet dispenser distal tip from extending entirely through the hole and contacting electrodes in the DBET. The rod holder is configured to be removably coupled to the quadrupole metal rods so that a location of the rod holder relative to the metal rods is adjustable.

    METHOD FOR ENSURING MICROBIOLOGICAL PURITY OF A SINGLE-USE DEVICE, AND COVER FOR A FLUID CONNECTION OF A SEPARATION UNIT FOR USE IN SUCH A METHOD
    3.
    发明公开
    METHOD FOR ENSURING MICROBIOLOGICAL PURITY OF A SINGLE-USE DEVICE, AND COVER FOR A FLUID CONNECTION OF A SEPARATION UNIT FOR USE IN SUCH A METHOD 审中-公开

    公开(公告)号：US20240001371A1

    公开(公告)日：2024-01-04

    申请号：US18037154

    申请日：2021-11-16

    Applicant: Sartorius Stedim Biotech GmbH

    Inventor： Johannes WORTMEYER ,  Thomas LOEWE ,  Florian MIETH

    IPC: B01L3/00 ,  A61L2/08 ,  A61L2/07

    CPC classification number: B01L13/02 ,  B01L3/565 ,  B01L2200/0689 ,  A61L2/081 ,  A61L2/07 ,  B01L3/561

    Abstract: A method for ensuring a microbiological purity of a single-use device for carrying out a biotechnological process, the single-use device including at least one gamma-sterilizable component which is formed from materials suitable for a sterilization by gamma radiation, and at least one non-gamma-sterilizable subunit which contains a material unsuitable for a sterilization by gamma radiation. Both the component and the subunit each have an area that comes into contact with a process medium when the biotechnological process is carried out. The method includes the steps of sterilizing the gamma-sterilizable component by gamma radiation; protecting the medium-contacting area of the gamma-sterilizable component by a sterile barrier; sterilizing the non-gamma-sterilizable subunit with superheated steam; protecting the medium-contacting area of the non-gamma-sterilizable subunit by a sterile barrier; removing the sterile barriers; and mounting the gamma-sterilized component and the superheated steam-sterilized subunit in the single-use device immediately after removing the sterile barriers.

    Method of facilitating the handling of a volume of fluid
    4.
    发明授权
    Method of facilitating the handling of a volume of fluid 有权

    公开(公告)号：US11724262B2

    公开(公告)日：2023-08-15

    申请号：US17032671

    申请日：2020-09-25

    Applicant: Wisconsin Alumni Research Foundation

    Inventor： David J. Beebe ,  Jay W. Warrick ,  David J. Guckenberger, Jr.

    IPC: B01L3/00

    CPC classification number: B01L3/52 ,  B01L3/561 ,  B01L3/563 ,  B01L2300/043 ,  B01L2300/0832 ,  B01L2400/0409

    Abstract: A device and method are provided to facilitate the handling of a volume of fluid. The device includes an elongated tube having an open first end and a second end. The tube defines a reservoir for receiving the volume of fluid. A stanchion has a first end received within the reservoir of the tube and a second end projecting from the open end of the elongated tube. In operation, the elongated tube is deposited in a first capsule having fluid therein. The first capsule is centrifuged such that the volume of fluid is received in a reservoir in the tube through the open end. The tube is removed from the first capsule and positioned in a second capsule such that the open end of the tube is spaced from a closed end of the second capsule. The second capsule is centrifuged such that the volume of fluid is expelled from the reservoir of the tube.

    SPECIMEN CUP AND TRANSFER APPARATUS
    10.
    发明申请
    SPECIMEN CUP AND TRANSFER APPARATUS 审中-公开
    样品杯和转印装置

    公开(公告)号：US20170050184A1

    公开(公告)日：2017-02-23

    申请号：US14831738

    申请日：2015-08-20

    Applicant: Emanuele A. Mangiafico ,  Darin Senna ,  David Facchini ,  Andrew Cervasio

    Inventor： Emanuele A. Mangiafico ,  Darin Senna ,  David Facchini ,  Andrew Cervasio

    IPC: B01L3/00

    CPC classification number: B01L3/502 ,  B01L3/561 ,  B01L2200/0615 ,  B01L2300/041 ,  B01L2300/046 ,  B01L2300/0672 ,  B01L2300/0832

    Abstract: An apparatus for collecting, storing and transferring a liquid specimen includes a first cup for collecting a liquid specimen and a lid attachable to the first cup for closing an opening in the first cup. The lid defines a protruding collar, the lid and the collar define an aperture extending through the lid and a length of the collar. The apparatus further includes a transfer assembly including a tube having first and second ends, the first end defining a point, the second end configured for insertion through the aperture in the collar for transferring a liquid specimen from the first cup through the tube. The first end of the tube extends through a bottom of a second cup and into the second cup. The first end of the tube configured for insertion into an evacuated vial for transferring a liquid specimen from the first cup to the vial.

    Abstract translation: 用于收集，储存和转移液体试样的装置包括用于收集液体试样的第一杯和可附接到第一杯的盖，用于封闭第一杯中的开口。 盖子限定了一个突出的套环，盖子和套环限定了延伸穿过盖子的一个孔口和一个长度的套环。 所述设备还包括传送组件，其包括具有第一端和第二端的管，所述第一端限定点，所述第二端被配置为插入穿过所述套环中的孔，用于将液体样本从所述第一杯传送通过所述管。 管的第一端延伸穿过第二杯的底部并进入第二杯。 管的第一端构造成用于插入到抽空的小瓶中，用于将液体样品从第一杯转移到小瓶。

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