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    METHOD FOR PROCESSING COALESCENCE-INHIBITED EMULSIONS FROM WHOLE-CELL BIOTRANSFORMATIONS WITH COMPRESSED OR SUPERCRITICAL GASES,IN PARTICULAR WITH CARBON DIOXIDE
    1.
    发明申请
    METHOD FOR PROCESSING COALESCENCE-INHIBITED EMULSIONS FROM WHOLE-CELL BIOTRANSFORMATIONS WITH COMPRESSED OR SUPERCRITICAL GASES,IN PARTICULAR WITH CARBON DIOXIDE 失效
    从具有压缩或超临界气体（特别是二氧化碳）的全细胞生物降解过程中处理含有抑制性乳剂的方法

    公开(公告)号：US20100145082A1

    公开(公告)日：2010-06-10

    申请号：US12452769

    申请日：2008-07-20

    申请人： Gabriele Sadowski ,  Andreas Schmid ,  Bruno Buehler ,  Michael Goernert ,  Christoph Brandenbusch

    发明人： Gabriele Sadowski ,  Andreas Schmid ,  Bruno Buehler ,  Michael Goernert ,  Christoph Brandenbusch

    IPC分类号： C07D301/32

    CPC分类号： C12N1/02 ,  B01D17/044 ,  B01D17/047 ,  B01D21/02 ,  C12N1/06

    摘要： The method presented represents a possibility for separating emulsions derived from whole-cell biotransformations, which method makes it possible to effectively separate stable emulsions derived from typical biocatalytic two-phase processes that result in connection with such a biotransformation, by means of at least one compressed or supercritical gas. In this connection, a supercritical extraction to obtain the valuable product can follow directly, because of the use of compressed or supercritical gas as the separation agent. It is unimportant, in this connection, whether the valuable product is present in the aqueous or the organic phase. Recycling of the organic phase is possible, since the surfactant cell components, which are decisively responsible for the formation of the stable emulsion, can be separated off by means of sedimentation, because of the treatment. The separation that is achieved remains in existence even after the compressed or supercritical gas has gassed out, so that aside from extraction, other methods for product isolation can also follow, if this is necessary. In this connection, the invention contains tremendous potential for industrial use of biocatalytical two-phase processes, which are of great interest economically and ecologically.

    摘要翻译： 所提出的方法代表了分离衍生自全细胞生物转化的乳液的可能性，该方法使得有可能通过至少一种压缩的方法有效地分离来自典型的生物催化两相过程的稳定乳剂，其导致与这种生物转化的连接 或超临界气体。 在这方面，由于使用压缩或超临界气体作为分离剂，所以获得有价物质的超临界萃取可以直接进行。 在这方面，有价值的产品是否存在于水相或有机相中是不重要的。 有机相的回收是可能的，因为由于处理，可以通过沉降来分离出决定性地负责形成稳定乳液的表面活性剂细胞成分。 即使在压缩或超临界气体放气之后，仍然存在分离，因此除了提取之外，如果需要，也可以遵循其他用于产物分离的方法。 在这方面，本发明在生物催化二相工艺的工业化应用方面具有巨大的潜力，这在生产和经济上都是非常有意义的。

    Method for processing coalescence-inhibited emulsions from whole-cell biotransformations with compressed or supercritical gases
    2.
    发明授权
    Method for processing coalescence-inhibited emulsions from whole-cell biotransformations with compressed or supercritical gases 失效
    用压缩或超临界气体从全细胞生物转化处理聚结抑制乳剂的方法

    公开(公告)号：US08431358B2

    公开(公告)日：2013-04-30

    申请号：US12452769

    申请日：2008-07-20

    申请人： Gabriele Sadowski ,  Andreas Schmid ,  Bruno Buehler ,  Michael Goernert ,  Christoph Brandenbusch

    发明人： Gabriele Sadowski ,  Andreas Schmid ,  Bruno Buehler ,  Michael Goernert ,  Christoph Brandenbusch

    IPC分类号： C12P1/00

    CPC分类号： C12N1/02 ,  B01D17/044 ,  B01D17/047 ,  B01D21/02 ,  C12N1/06

    摘要： The method separates emulsions derived from whole-cell biotransformations, including stable emulsions derived from typical biocatalytic two-phase processes that result with such a biotransformation. A supercritical extraction to obtain the valuable product can follow directly, because of the use of compressed or supercritical gas as the separation agent. It is unimportant whether the valuable product is present in the aqueous or the organic phase. Recycling of the organic phase is possible, since the surfactant cell components decisively responsible for the formation of the stable emulsion can be separated off via sedimentation, because of the treatment. The achieved separation remains in existence even after the gas has gassed out, so that aside from extraction, other methods for product isolation can also follow, if necessary.

    摘要翻译： 该方法分离衍生自全细胞生物转化的乳液，包括衍生自通过这种生物转化产生的典型生物催化两相过程的稳定乳剂。 由于采用压缩或超临界气体作为分离剂，因此获得有价物质的超临界萃取可以直接进行。 有价值的产品是否存在于水相或有机相中是不重要的。 有机相的回收是可能的，因为由于处理，可以通过沉淀分离决定性地负责形成稳定乳液的表面活性剂细胞成分。 实现的分离仍然存在，即使在气体放出之后，除了提取之外，如果需要，也可以遵循用于产物分离的其它方法。

    Device and method for remote operation of a vehicle from a mother vehicle
    6.
    发明申请
    Device and method for remote operation of a vehicle from a mother vehicle 审中-公开
    从母车辆远程操作车辆的装置和方法

    公开(公告)号：US20050060066A1

    公开(公告)日：2005-03-17

    申请号：US10896662

    申请日：2004-07-22

    申请人： Bruno Buehler ,  Urban Thoeni

    发明人： Bruno Buehler ,  Urban Thoeni

    IPC分类号： G05D1/00 ,  G06F17/00

    CPC分类号： G05D1/0038 ,  G05D2201/0213

    摘要： A device (10) having a first vehicle (11) and a second vehicle (13) which are connected to one another via a communication link (12). The first vehicle (11) has operational units (21), which are actuated in the typical way during driving. In the first vehicle (11), there are connections (23) for transmitting vehicle information (24) which is correlated to the actuation of the operational units (21). Switching means (28) are used for the purpose of switching over the first vehicle (11) from a driving mode into a remote operation mode. A transmitter (27) is used for converting the vehicle information (24) into signals and for transmitting the signals from the first vehicle (11) to the second vehicle (13). The second vehicle (13) includes a receiver (31) for receiving the signals and for converting them into control information. In addition, control elements (32) are provided, which are activatable from the first vehicle (11) by actuating the operational units (21), after the switching means (28) have been brought into the remote operation mode.

    摘要翻译： 具有经由通信链路（12）彼此连接的第一车辆（11）和第二车辆（13）的装置（10）。 第一车辆（11）具有在驾驶期间以典型方式致动的操作单元（21）。 在第一车辆（11）中，存在用于传送与操作单元（21）的致动相关的车辆信息（24）的连接（23）。 切换装置（28）用于将第一车辆（11）从驾驶模式切换到远程操作模式。 发射器（27）用于将车辆信息（24）转换为信号并将信号从第一车辆（11）发送到第二车辆（13）。 第二车辆（13）包括用于接收信号并将其转换成控制信息的接收器（31）。 此外，在切换装置（28）进入远程操作模式之后，提供控制元件（32），其通过致动操作单元（21）可从第一车辆（11）激活。