Suturing Devices and Methods
    1.
    发明申请
    Suturing Devices and Methods 审中-公开
    缝合装置和方法

    公开(公告)号:US20070276408A1

    公开(公告)日:2007-11-29

    申请号:US10570521

    申请日:2004-09-02

    IPC分类号: A61B17/10

    摘要: Disclosed is a T-fastener delivery device. The device includes a belt and a pusher rod. The belt includes a plurality of slots for holding a plurality of T-bars substantially parallel to one another in a side-by-side arrangement; and the belt is moveable such that the slots can be sequentially aligned with the pusher rod. Also disclosed are methods for creating a gastric pouch in the stomach of an obese patient and methods for reducing lower esophageal sphincter distraction with gastric filling in a subject. Suturing systems are also disclosed One suturing system includes a plurality of T-fasteners and a continuous suture connecting the plurality of T-fasteners. The T-fastener comprises a cylindrical bar having a filament loop attached thereto substantially at the cylindrical bar's axial midpoint, and the continuous suture slidably passes through the T-fasteners' filament loops. Another suturing system includes a plurality of T-fasteners; and a continuous suture connecting the plurality of T-fasteners. The T-fastener comprises two cylindrical bars connected by a filament, and the continuous suture slidably passes through a loop formed by the T-fasteners' filaments.

    摘要翻译: 公开了一种T型紧固件输送装置。 该装置包括带和推杆。 所述带包括多个槽,所述多个槽用于以并排布置彼此基本平行地保持多个T形杆; 并且带可移动,使得槽可以顺序地与推杆对准。 还公开了用于在肥胖患者的胃中产生胃袋的方法以及用于在受试者中用胃灌注减少食管下括约肌分心的方法。 还公开了缝合系统一个缝合系统包括多个T形紧固件和连接多个T形紧固件的连续缝合线。 T型紧固件包括一个圆柱形杆,其具有大致在圆柱形杆的轴向中点附接的细丝环,并且连续缝合线可滑动地穿过T形紧固件的细丝环。 另一缝合系统包括多个T形紧固件; 以及连接多个T形紧固件的连续缝合线。 T形紧固件包括由细丝连接的两个圆柱形杆,并且连续缝合线可滑动地穿过由T形紧固件的细丝形成的环。

    NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES
    2.
    发明申请
    NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES 审中-公开
    核酸序列与可释放的核酸探针

    公开(公告)号:US20090286694A1

    公开(公告)日:2009-11-19

    申请号:US12511751

    申请日:2009-07-29

    IPC分类号: C40B30/04 C40B40/08

    摘要: A process is provided for identifying a complementary target nucleic acid. The process includes the hybridization of a nucleic acid probe to a carrier to form a nucleic acid probe-carrier complex. The complex is placed in a compartment bounded by a media permeable to the nucleic acid probe and exclusive of both the carrier and the complex. The complex is then denatured, with the nucleic acid probe transported through the media and into contact with the target nucleic acid. The nucleic acid probe hybridizes to the complementary target nucleic acid to yield a probe-target double stranded complex. A non-complementary nucleic acid probe, independent probe-target complex is returned to the compartment and given an opportunity to rehybridize to the carrier. A determination as to whether at least one of the complementary target nucleic acid or the carrier is present as a complex provides information as to probe sequences complementary to the target nucleic acid.

    摘要翻译: 提供了用于鉴定互补靶核酸的方法。 该方法包括将核酸探针与载体杂交以形成核酸探针 - 载体复合物。 将复合物置于由可渗透核酸探针的介质限定的区域中,并且不包括载体和复合物两者。 然后将复合物变性,核酸探针通过培养基传输并与靶核酸接触。 核酸探针与互补靶核酸杂交以产生探针 - 靶双链复合物。 将非互补核酸探针,独立的探针 - 靶复合物返回到隔室,给予再载体载体的机会。 作为复合物存在至少一种互补靶核酸或载体的确定提供了与靶核酸互补的探针序列的信息。

    NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES
    3.
    发明申请
    NUCLEIC ACID ARRAY WITH RELEASEABLE NUCLEIC ACID PROBES 审中-公开
    核酸序列与可释放的核酸探针

    公开(公告)号:US20080044822A1

    公开(公告)日:2008-02-21

    申请号:US11465875

    申请日:2006-08-21

    IPC分类号: C12Q1/68

    摘要: A process is provided for identifying a complementary target nucleic acid. The process includes the hybridization of a nucleic acid probe to a carrier to form a nucleic acid probe-carrier complex. The complex is placed in a compartment bounded by a media permeable to the nucleic acid probe and exclusive of both the carrier and the complex. The complex is then denatured, with the nucleic acid probe transported through the media and into contact with the target nucleic acid. The nucleic acid probe hybridizes to the complementary target nucleic acid to yield a probe-target double stranded complex. A non-complementary nucleic acid probe, independent probe-target complex is returned to the compartment and given an opportunity to rehybridize to the carrier. A determination as to whether at least one of the complementary target nucleic acid or the carrier is present as a complex provides information as to probe sequences complementary to the target nucleic acid.

    摘要翻译: 提供了用于鉴定互补靶核酸的方法。 该方法包括将核酸探针与载体杂交以形成核酸探针 - 载体复合物。 将复合物置于由可渗透核酸探针的介质限定的区域中,并且不包括载体和复合物两者。 然后将复合物变性,核酸探针通过培养基传输并与靶核酸接触。 核酸探针与互补靶核酸杂交以产生探针 - 靶双链复合物。 将非互补核酸探针,独立的探针 - 靶复合物返回到隔室,给予再载体载体的机会。 作为复合物存在至少一种互补靶核酸或载体的确定提供了与靶核酸互补的探针序列的信息。