公开(公告)号：US07853089B2

公开(公告)日：2010-12-14

申请号：US11711738

申请日：2007-02-27

申请人： Gal Shafirstein ,  Xiaowei Xu ,  Mutlu Mete

发明人： Gal Shafirstein ,  Xiaowei Xu ,  Mutlu Mete

IPC分类号： G06K9/36

CPC分类号： G06K9/0014 ,  Y10S128/922 ,  Y10S128/925

摘要： An automated method for analyzing whether all cancerous or abnormal tissue has been removed as a result of surgical resection is disclosed. A number of tissue section slides are prepared representing all or a relatively large percentage of the tissue sample, and high-resolution digital microscopic images are formed of the sections. A clustering algorithm forms an image showing the healthy tissue margins, such representation being stored in a file of significantly smaller size than the original photograph. These two-dimensional image files may be formed into a three-dimensional image of the entire resected tissue, thereby improving the accuracy and ease by which a pathologist may determine if further surgery or radiation therapy, for example, are indicated.

摘要翻译： 公开了一种用于分析是否已经通过手术切除术去除所有癌性或异常组织的自动化方法。 准备了许多代表所有或相对较大比例的组织样本的组织切片，并且由分段形成高分辨率数字显微镜图像。 聚类算法形成显示健康组织边缘的图像，这种表示被存储在比原始照片小得多的文件中。 这些二维图像文件可以形成为整个切除的组织的三维图像，从而提高了病理学家可以确定是否进一步手术或放射疗法的准确性和容易程度。

公开(公告)号：US20080205776A1

公开(公告)日：2008-08-28

申请号：US11711738

申请日：2007-02-27

申请人： Gal Shafirstein ,  Xiaowei Xu ,  Mutlu Mete

发明人： Gal Shafirstein ,  Xiaowei Xu ,  Mutlu Mete

IPC分类号： G06K9/36

CPC分类号： G06K9/0014 ,  Y10S128/922 ,  Y10S128/925

摘要： An automated method for analyzing whether all cancerous or abnormal tissue has been removed as a result of surgical resection is disclosed. A number of tissue section slides are prepared representing all or a relatively large percentage of the tissue sample, and high-resolution digital microscopic images are formed of the sections. A clustering algorithm forms an image showing the healthy tissue margins, such representation being stored in a file of significantly smaller size than the original photograph. These two-dimensional image files may be formed into a three-dimensional image of the entire resected tissue, thereby improving the accuracy and ease by which a pathologist may determine if further surgery or radiation therapy, for example, are indicated.

摘要翻译： 公开了一种用于分析是否已经通过手术切除术去除所有癌性或异常组织的自动化方法。 准备了许多代表所有或相对较大比例的组织样本的组织切片，并且由分段形成高分辨率数字显微镜图像。 聚类算法形成显示健康组织边缘的图像，这种表示被存储在比原始照片小得多的文件中。 这些二维图像文件可以形成为整个切除的组织的三维图像，从而提高了病理学家可以确定是否进一步手术或放射疗法的准确性和容易程度。

公开(公告)号：US20090198793A1

公开(公告)日：2009-08-06

申请号：US12012064

申请日：2008-01-31

申请人： Thanabalan Thavittupitchai Paul ,  John Alan Gervais ,  Xiaowei Xu

发明人： Thanabalan Thavittupitchai Paul ,  John Alan Gervais ,  Xiaowei Xu

IPC分类号： G06F15/16

CPC分类号： G06F11/0772 ,  G06F9/4401 ,  G06F11/07 ,  G06F11/0706 ,  G06F11/0787 ,  G06F11/3055 ,  H04L41/06 ,  H04L43/00 ,  H04L43/0817 ,  H04N21/442 ,  H04N21/4424 ,  H04N21/4425 ,  H04N21/4432 ,  H04N21/4882 ,  H04N21/6581

摘要： The boot process of a content/service receiver is dynamically monitored to provide error and/or status information in a step-by-step and/or in a single-snapshot manner. This can be accomplished by, for example, utilizing an application thread running within, and/or, outside the context of the boot code. Status information from, for example, software drivers and/or any other software/hardware/middleware components, is acquired by the application thread utilizing any mechanism, for example, event-driven and/or polling, and then relayed to an external entity, which can be locally and/or remotely located. The external entity can be reached by any means of standard and/or proprietary medium and protocols available, if necessary. The relayed information can then be used, for example, for displaying to a user via a graphical user interface, and/or can be recorded and the like.

摘要翻译： 动态地监视内容/服务接收器的引导过程，以逐步和/或以单一快照方式提供错误和/或状态信息。 这可以通过例如利用在引导代码的上下文内和/或之外运行的应用程序线程来实现。 来自例如软件驱动程序和/或任何其他软件/硬件/中间件组件的状态信息由应用程序线程利用任何机制（例如，事件驱动和/或轮询）获取，然后被转发到外部实体， 其可以在本地和/或远程位置。 如果需要，外部实体可以通过任何标准和/或专有媒体和协议的方式达成。 然后可以使用中继的信息，例如，经由图形用户界面向用户显示和/或可以记录等。

公开(公告)号：US09760424B2

公开(公告)日：2017-09-12

申请号：US12012064

申请日：2008-01-31

申请人： Thanabalan Thavittupitchai Paul ,  John Alan Gervais ,  Xiaowei Xu

发明人： Thanabalan Thavittupitchai Paul ,  John Alan Gervais ,  Xiaowei Xu

IPC分类号： G06F11/07 ,  H04N21/442 ,  G06F11/30 ,  G06F9/44 ,  H04N21/4425 ,  H04N21/443 ,  H04L12/24 ,  H04L12/26 ,  H04N21/488 ,  H04N21/658

CPC分类号： G06F11/0772 ,  G06F9/4401 ,  G06F11/07 ,  G06F11/0706 ,  G06F11/0787 ,  G06F11/3055 ,  H04L41/06 ,  H04L43/00 ,  H04L43/0817 ,  H04N21/442 ,  H04N21/4424 ,  H04N21/4425 ,  H04N21/4432 ,  H04N21/4882 ,  H04N21/6581

摘要： The boot process of a content/service receiver is dynamically monitored to provide error and/or status information in a step-by-step and/or in a single-snapshot manner. This can be accomplished by, for example, utilizing an application thread running within, and/or, outside the context of the boot code. Status information from, for example, software drivers and/or any other software/hardware/middleware components, is acquired by the application thread utilizing any mechanism, for example, event-driven and/or polling, and then relayed to an external entity, which can be locally and/or remotely located. The external entity can be reached by any means of standard and/or proprietary medium and protocols available, if necessary. The relayed information can then be used, for example, for displaying to a user via a graphical user interface, and/or can be recorded and the like.

公开(公告)号：US20110200566A1

公开(公告)日：2011-08-18

申请号：US13121572

申请日：2009-09-29

申请人： Xiaowei Xu ,  Hong Yu

发明人： Xiaowei Xu ,  Hong Yu

IPC分类号： A61K35/12 ,  C12N5/071 ,  A61P17/00

CPC分类号： A61K35/36 ,  A61K35/12 ,  C12N5/0625 ,  C12N5/0626 ,  C12N2501/115 ,  C12N2501/125 ,  C12N2501/998 ,  Y02A50/471

摘要： Compositions and methods for darkening skin and treating vitiligo are provided.

摘要翻译： 提供了使皮肤变黑和治疗白癜风的组合物和方法。

公开(公告)号：US08999706B2

公开(公告)日：2015-04-07

申请号：US11911400

申请日：2006-04-12

申请人： Xiaowei Xu ,  Hong Yu ,  Douglas Dong Fang ,  Meenhard Herlyn

发明人： Xiaowei Xu ,  Hong Yu ,  Douglas Dong Fang ,  Meenhard Herlyn

IPC分类号： C12N5/00 ,  C12N15/00 ,  C12N5/074 ,  C12N5/071

CPC分类号： C12N5/0607 ,  C12N5/0628 ,  C12N2500/44 ,  C12N2501/11 ,  C12N2501/115

摘要： Isolated human multipotent adult stem cell and isolated populations of cells that include human multipotent adult stem cells are disclosed. Human hair-follicle derived multipotent adult stem cells and methods of preparing isolated populations of cells that include human multipotent adult stem cells are disclosed. Isolated human hair-follicle derived multipotent adult stem cell that can differentiate in culture into a neuronal cell, a glial cell, a melanocyte cell, a muscle cell, an osteocyte, a chondrocyte, and a lymphocyte. Isolated human hair-follicle derived multipotent adult stem cell that can grow in cell culture in spheres are disclosed. Human pancreas derived multipotent adult stem cells, human liver derived multipotent adult stem cells, human kidney derived multipotent adult stem cells, human heart derived multipotent adult stem cells, human neural derived multipotent adult stem cells and methods of preparing isolated populations of cells that include such human multipotent adult stem cells are disclosed. Method of treating an individual who has diabetes, cardiac muscle damage, muscle damage and disease, neurodegenerative disease or nerve damage or injury, bone loss, damage and/or disease, cartilage loss, damage and/or disease, hair loss and immune disorders, are disclosed.

摘要翻译： 公开了分离的人多能成体干细胞和包括人多潜能成体干细胞的分离的细胞群。 公开了人毛囊衍生的多能成体干细胞和制备包括人多潜能成体干细胞的分离的细胞群的方法。 分离的人毛囊衍生的多能成体干细胞，其可以在培养物中分化成神经元细胞，胶质细胞，黑素细胞，肌细胞，骨细胞，软骨细胞和淋巴细胞。 公开了可以在球体的细胞培养物中生长的分离的人毛囊衍生的多潜能成体干细胞。 人胰腺来源的多能成体干细胞，人肝来源的多潜能成体干细胞，人肾来源的多潜能成体干细胞，人心源性多潜能成体干细胞，人神经衍生多潜能成体干细胞以及制备分离的细胞群的方法， 公开了人多能成体干细胞。 治疗患有糖尿病，心肌损伤，肌肉损伤和疾病，神经变性疾病或神经损伤或损伤，骨丢失，损伤和/或疾病，软骨损失，损伤和/或疾病，脱发和免疫疾病的个体的方法， 被披露。

公开(公告)号：US20090130065A1

公开(公告)日：2009-05-21

申请号：US11911400

申请日：2006-04-12

申请人： Xiaowei Xu ,  Hong Yu ,  Douglas Dong Fang ,  Meenhard Herlyn

发明人： Xiaowei Xu ,  Hong Yu ,  Douglas Dong Fang ,  Meenhard Herlyn

IPC分类号： A61K35/12 ,  C12N5/08

CPC分类号： C12N5/0607 ,  C12N5/0628 ,  C12N2500/44 ,  C12N2501/11 ,  C12N2501/115

摘要： Isolated human multipotent adult stem cell and isolated populations of cells that include human multipotent adult stem cells are disclosed. Human hair-follicle derived multipotent adult stem cells and methods of preparing isolated populations of cells that include human multipotent adult stem cells are disclosed. Isolated human hair-follicle derived multipotent adult stem cell that can differentiate in culture into a neuronal cell, a glial cell, a melanocyte cell, a muscle cell, an osteocyte, a chondrocyte, and a lymphocyte. Isolated human hair-follicle derived multipotent adult stem cell that can grow in cell culture in spheres are disclosed. Human pancreas derived multipotent adult stem cells, human liver derived multipotent adult stem cells, human kidney derived multipotent adult stem cells, human heart derived multipotent adult stem cells, human neural derived multipotent adult stem cells and methods of preparing isolated populations of cells that include such human multipotent adult stem cells are disclosed. Method of treating an individual who has diabetes, cardiac muscle damage, muscle damage and disease, neurodegenerative disease or nerve damage or injury, bone loss, damage and/or disease, cartilage loss, damage and/or disease, hair loss and immune disorders, are disclosed.

摘要翻译： 公开了分离的人多能成体干细胞和包括人多潜能成体干细胞的分离的细胞群。 公开了人毛囊衍生的多能成体干细胞和制备包括人多潜能成体干细胞的分离的细胞群的方法。 分离的人毛囊衍生的多能成体干细胞，其可以在培养物中分化成神经元细胞，胶质细胞，黑素细胞，肌细胞，骨细胞，软骨细胞和淋巴细胞。 公开了可以在球体的细胞培养物中生长的分离的人毛囊衍生的多潜能成体干细胞。 人胰腺来源的多能成体干细胞，人肝来源的多潜能成体干细胞，人肾来源的多潜能成体干细胞，人心源性多潜能成体干细胞，人神经衍生多潜能成体干细胞以及制备分离的细胞群的方法， 公开了人多能成体干细胞。 治疗患有糖尿病，心肌损伤，肌肉损伤和疾病，神经变性疾病或神经损伤或损伤，骨丢失，损伤和/或疾病，软骨损失，损伤和/或疾病，脱发和免疫疾病的个体的方法， 被披露。