METHOD OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDS
    3.
    发明申请
    METHOD OF NONSPECIFIC TARGET CAPTURE OF NUCLEIC ACIDS 审中-公开
    核酸非目标捕获方法

    公开(公告)号:US20160122746A1

    公开(公告)日:2016-05-05

    申请号:US14990508

    申请日:2016-01-07

    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.

    Abstract translation: 通过使用捕获探针非特异性结合靶核酸并通过在捕获探针上具有一个成员的特异性结合对与固定化探针上的一个成员特异性结合固定的探针来从样品捕获靶核酸的方法 被披露。 公开了包含捕获探针的组合物,其通过结合反应混合物的溶液相中的特异性结合对的成员非特异性地结合靶核酸而特异性结合固定的探针。

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