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公开(公告)号:US10882920B2
公开(公告)日:2021-01-05
申请号:US15525791
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC分类号: C07K16/40 , A61K47/68 , A61K39/00 , G01N33/573
摘要: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
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公开(公告)号:US20180057604A1
公开(公告)日:2018-03-01
申请号:US15525821
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan WU , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/22 , C07K16/2881 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C12Y304/23046 , G01N33/6896 , G01N2333/70582 , G01N2333/96472 , G01N2800/28 , G01N2800/52
摘要: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号:US20210206877A1
公开(公告)日:2021-07-08
申请号:US17113711
申请日:2020-12-07
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC分类号: C07K16/40 , A61K47/68 , G01N33/573
摘要: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders
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公开(公告)号:US11008403B2
公开(公告)日:2021-05-18
申请号:US15525821
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
摘要: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号:US11746160B2
公开(公告)日:2023-09-05
申请号:US17113711
申请日:2020-12-07
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC分类号: C12N15/52 , C07K16/40 , A61K47/68 , G01N33/573 , A61K39/00
CPC分类号: C07K16/40 , A61K47/6871 , C12N15/52 , C12Y304/23046 , G01N33/573 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/90 , C07K2317/92 , G01N2333/96472 , G01N2800/28 , G01N2800/52
摘要: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
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公开(公告)号:US20170362339A1
公开(公告)日:2017-12-21
申请号:US15525791
申请日:2015-11-18
申请人: Genentech, Inc. , Adimab LLC
发明人: Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan WU , Eric Krauland , Michael Feldhaus
IPC分类号: C07K16/40 , G01N33/573 , A61K47/68 , A61K39/00
CPC分类号: C07K16/40 , A61K47/6871 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C12Y304/23046 , G01N33/573 , G01N2333/96472 , G01N2800/28 , G01N2800/52
摘要: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
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公开(公告)号:US20170058049A1
公开(公告)日:2017-03-02
申请号:US15234649
申请日:2016-08-11
申请人: Genentech, Inc.
发明人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
摘要翻译: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号:US20230303682A1
公开(公告)日:2023-09-28
申请号:US18004550
申请日:2021-07-16
申请人: Genentech, Inc.
发明人: Cecilia Pui Chi Chiu , Yan Wu , Adel Mahmoud ElSohly , Daniel George Lafkas , Jian Mehr-Dean Payandeh , Hoangdung Dang Ho , Siao-Ping Tsai
IPC分类号: C07K16/28 , A61K45/06 , A61K39/395 , A61P11/00
CPC分类号: C07K16/28 , A61K39/3955 , A61K45/06 , A61P11/00 , C07K2317/24 , C07K2317/34 , C07K2317/35 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-Notch2 antibodies and methods of using the same.
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公开(公告)号:US09879094B2
公开(公告)日:2018-01-30
申请号:US15234649
申请日:2016-08-11
申请人: Genentech, Inc.
发明人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC分类号: C07H21/04 , C07K16/18 , C12P21/08 , C07K16/40 , A61K39/395 , G01N33/573 , C12P21/00 , A61K47/68 , A61K39/00
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
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10.
公开(公告)号:US09266961B2
公开(公告)日:2016-02-23
申请号:US13918755
申请日:2013-06-14
申请人: Genentech, Inc.
发明人: Yan Wu , Cecilia Pui Chi Chiu , Daniel K. Kirchhofer , Andrew Peterson , Ganesh A. Kolumam , Monica Kong Beltran , Paul Moran , Wei Li , Xanthe M. Lam , Lin Luis , Ada Hui
IPC分类号: C07K16/40 , A61K39/395 , A61K39/00
CPC分类号: C07K16/40 , A61K39/39591 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The invention provides anti-PCSK9 antibodies, formulations, dosing regimens, and methods of using the same.
摘要翻译: 本发明提供抗PCSK9抗体,制剂,给药方案及其使用方法。
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