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    Method and apparatus for adjusting the sensing threshold of a cardiac rhythm management device
    1.
    发明申请
    Method and apparatus for adjusting the sensing threshold of a cardiac rhythm management device 失效
    用于调节心律管理装置的感测阈值的方法和装置

    公开(公告)号：US20050004613A1

    公开(公告)日：2005-01-06

    申请号：US10910193

    申请日：2004-08-03

    申请人： Geng Zhang ,  Oingsheng Zhu ,  Laura Mepham ,  Jesse Hartley

    发明人： Geng Zhang ,  Oingsheng Zhu ,  Laura Mepham ,  Jesse Hartley

    IPC分类号： A61N1/368 ,  A61N1/37

    CPC分类号： A61N1/3704 ,  A61N1/368

    摘要： A method and apparatus for automatically adjusting the sensing threshold of cardiac rhythm management devices. The invention is particularly suited for implementation in devices such as implantable cardiac pacemakers and implantable cardioverter/defibrillators. A method and apparatus are provided in which a noise level and signal level for a sensing channel are determined for each cardiac cycle with the sensing threshold of the channel being adjusted in accordance therewith.

    摘要翻译： 一种用于自动调节心律管理装置感测阈值的方法和装置。 本发明特别适用于诸如可植入心脏起搏器和植入式心律转复器/去纤颤器的装置中的实现。 提供了一种方法和装置，其中针对每个心动周期确定用于感测通道的噪声电平和信号电平，同时根据该通道的感测阈值进行调整。

    DETECTION OF PLEURAL EFFUSION USING TRANSTHORACIC IMPEDANCE
    3.
    发明申请
    DETECTION OF PLEURAL EFFUSION USING TRANSTHORACIC IMPEDANCE 有权
    使用TRANSTHORACIC阻抗检测临时效应

    公开(公告)号：US20080108907A1

    公开(公告)日：2008-05-08

    申请号：US11972405

    申请日：2008-01-10

    申请人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

    发明人： Jeffrey Stahmann ,  John Hatlestad ,  Jesse Hartley ,  Richard Fogoros

    IPC分类号： A61B5/085

    CPC分类号： A61B5/0205 ,  A61B5/0031 ,  A61B5/0535 ,  A61B5/1116 ,  A61B5/4869 ,  A61N1/36521 ,  A61N1/36535

    摘要： This patent document discusses systems, devices, and methods for increasing a sensitivity or specificity of thoracic fluid detection in a subject and differentiating between pleural effusion and pulmonary edema. In one example, a thoracic impedance measurement circuit senses a thoracic impedance signal. In another example, a processor receives the thoracic impedance signal and determines whether such thoracic impedance signal is “significant.” A significant thoracic impedance signal indicates the presence of thoracic fluid and may be recognized by comparing the thoracic impedance signal (or variation thereof) to a thoracic impedance threshold. When a significant thoracic impedance signal is recognized, the processor is adapted to detect one or both of: a pleural effusion indication and a pulmonary edema indication using one or a combination of: physiologic information, patient symptom information, and posture information. In another example, the thoracic impedance threshold is adjusted using such physiologic, patient symptom, or posture information.

    摘要翻译： 该专利文献讨论了用于增加受试者胸部液体检测的敏感性或特异性并区分胸腔积液和肺水肿的系统，装置和方法。 在一个示例中，胸部阻抗测量电路感测胸部阻抗信号。 在另一示例中，处理器接收胸部阻抗信号并确定这种胸部阻抗信号是否“显着”。 显着的胸部阻抗信号表示胸腔液的存在，并且可以通过将胸部阻抗信号（或其变化）与胸部阻抗阈值进行比较来识别。 当识别出显着的胸部阻抗信号时，处理器适合于使用生理信息，患者症状信息和姿势信息中的一个或组合来检测胸腔积液指示和肺水肿指示之一或两者。 在另一个例子中，使用这种生理，患者症状或姿势信息来调整胸阻抗阈值。

    Methods and systems for control of gas therapy
    6.
    发明申请
    Methods and systems for control of gas therapy 有权
    气体治疗方法和系统

    公开(公告)号：US20050061323A1

    公开(公告)日：2005-03-24

    申请号：US10929306

    申请日：2004-08-30

    申请人： Kent Lee ,  Jesse Hartley ,  Jeffrey Stahmann ,  Quan Ni

    发明人： Kent Lee ,  Jesse Hartley ,  Jeffrey Stahmann ,  Quan Ni

    IPC分类号： A61M16/00 ,  A62B7/00 ,  F16K31/02

    CPC分类号： A61M16/024 ,  A61M2016/0039 ,  A61M2230/04 ,  A61M2230/08 ,  A61M2230/205 ,  A61M2230/63

    摘要： A gas therapy system involves sensing the blood gas concentration of the patient and adapting a gas therapy based on the sensed gas concentration. Disordered breathing may be detected bases on blood gas concentration, and gas or cardiac electrical therapy may be adapted to treat the detected disordered breathing. One or more of sensing the blood gas concentration, detecting disordered breathing, or adapting the therapy may be performed at least in part implantably. The gas therapy is delivered to the patient through an external respiratory device, such as a positive airway pressure device.

    摘要翻译： 气体治疗系统包括感测患者的血液气体浓度，并根据检测到的气体浓度调整气体治疗。 可能会根据血气浓度检测到无效呼吸，气体或心脏电疗可适用于治疗检测到的无序呼吸。 感测血气浓度，检测无序呼吸或适应治疗的一种或多种可以至少部分地可植入地进行。 气体治疗通过外部呼吸装置（例如气道正压装置）输送给患者。

    Adaptive therapy for disordered breathing
    8.
    发明授权
    Adaptive therapy for disordered breathing 有权
    呼吸紊乱的自适应治疗

    公开(公告)号：US08321022B2

    公开(公告)日：2012-11-27

    申请号：US12731103

    申请日：2010-03-24

    申请人： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas R. Daum ,  Kent Lee

    发明人： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Quan Ni ,  Jesse Hartley ,  Douglas R. Daum ,  Kent Lee

    IPC分类号： A61N1/36

    CPC分类号： A61N1/362 ,  A61N1/3601

    摘要： An approach to providing disordered breathing therapy includes detecting disordered breathing and adapting a therapy to mitigate the disordered breathing. The therapy may be adapted to enhance therapy effectiveness, to provide therapy that reduces an impact of the therapy on the patient, or to achieve other therapeutic goals. Cardiac electrical therapy to mitigate the disordered breathing may include various cardiac pacing regimens and/or delivery of non-excitatory electrical stimulation to the heart.

    摘要翻译： 提供无序呼吸治疗的方法包括检测无序呼吸并适应治疗以减轻无序呼吸。 治疗可以适应于增强治疗有效性，提供减少治疗对患者的影响或实现其它治疗目标的治疗。 减轻无序呼吸的心脏电疗可能包括各种心脏起搏方案和/或向心脏递送非兴奋性电刺激。

    METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA
    10.
    发明申请
    METHOD AND APPARATUS FOR TREATING IRREGULAR VENTRICULAR CONTRACTIONS SUCH AS DURING ATRIAL ARRHYTHMIA 有权
    方法和装置，用于治疗非正常血管造影，如阿司匹林

    公开(公告)号：US20070016258A1

    公开(公告)日：2007-01-18

    申请号：US11423516

    申请日：2006-06-12

    申请人： David Krig ,  Jesse Hartley ,  Wyatt Stahl ,  Jeffrey Stahmann

    发明人： David Krig ,  Jesse Hartley ,  Wyatt Stahl ,  Jeffrey Stahmann

    IPC分类号： A61N1/00

    CPC分类号： A61N1/3956 ,  A61N1/3622 ,  A61N1/395

    摘要： A cardiac rhythm management system is capable of treating irregular ventricular heart contractions, such as during atrial tachyarrhythmias such as atrial fibrillation. A first indicated pacing interval is computed based at least partially on a most recent V-V interval duration between ventricular beats and a previous value of the first indicated pacing interval. Pacing therapy is provided based on either the first indicated pacing interval or also based on a second indicated pacing interval, such as a sensor-indicated pacing interval. A weighted averager such as an infinite impulse response (IIR) filter adjusts the first indicated pacing interval for sensed beats and differently adjusts the first indicated pacing interval for paced beats. The system regularizes ventricular rhythms by pacing the ventricle, but inhibits pacing when the ventricular rhythms are stable.

    摘要翻译： 心律管理系统能够治疗不规则的心室心脏收缩，例如在房性快速性心律失常如心房颤动期间。 至少部分地基于心室搏动之间的最新V-V间期持续时间和第一个起搏间隔的先前值来计算第一个起搏间隔。 基于第一个起搏间隔或基于第二个起搏间隔（例如传感器指示的起搏间隔）来提供起搏疗法。 诸如无限脉冲响应（IIR）滤波器的加权平均器调节感测节拍的第一个起搏间隔，并且针对起搏节奏不同地调节第一个起搏间隔。 系统通过起搏心室使心室节律正常化，但是当心室节律稳定时，可抑制起搏。