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    1-[2-(arylsulphonylamino)-1-oxoethyl]piperidine derivatives, their preparation and their therapeutic application
    1.
    发明授权
    1-[2-(arylsulphonylamino)-1-oxoethyl]piperidine derivatives, their preparation and their therapeutic application 失效
    1- [2-（芳基磺酰基氨基）-1-氧代乙基]哌啶衍生物，其制备及其治疗应用

    公开(公告)号：US5453430A

    公开(公告)日：1995-09-26

    申请号：US37972

    申请日：1993-03-29

    申请人： Gilbert Lassalle ,  Thomas Purcell ,  Daniel Galtier ,  Paul H. Williams ,  Frederic Galli

    发明人： Gilbert Lassalle ,  Thomas Purcell ,  Daniel Galtier ,  Paul H. Williams ,  Frederic Galli

    IPC分类号： A61K31/415 ,  A61K31/4427 ,  A61K31/445 ,  A61K31/47 ,  A61P7/02 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07K5/078 ,  C07D403/14

    CPC分类号： C07D233/64 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07K5/06139

    摘要： Compounds of formula (I) ##STR1## wherein R represents a ##STR2## group in which R.sub.2 is a hydrogen atom, a (C.sub.1 -C.sub.4)alkoxycarbonyl group, a carboxylic group, a sodium carboxylate group, a --CH.sub.2 OR.sub.4 group R.sub.4 being a hydrogen atom or a (C.sub.1 -C.sub.4)alkyl group or a (C.sub.1 -C.sub.4)acyl group, an amide group of the formula --CONR.sub.5 R.sub.6, or a --CN.sub.4 R.sub.5 group, R.sub.5 being a hydrogen atom or a (C.sub.1 -C.sub.4)alkyl group and R.sub.6 being a hydrogen atom, a (C.sub.1 -C.sub.4)alkyl group, a hydroxy group or a (C.sub.1 -C.sub.4)alkoxy group, and R.sub.3 is a (C.sub.1 -C.sub.4)alkyl group,R.sub.1 represents either a hydrogen atom or a (C.sub.1 -C.sub.4)alkyl group,X represents either a sulphur atom, an oxygen atom or a methylene group, n=1 or 2 andAr represents either a naphthalen-1-yl group substituted by a di(C.sub.1 -C.sub.4)alkylamino group, or a 6,7-di(C.sub.1 -C.sub.4)alkoxynaphthalen-1-yl group, or a quinolin-8-yl group substituted at 3 by a (C.sub.1 -C.sub.4)alkyl group, or a 1,2,3,4-tetrahydroquinolin-8-yl group substituted at 3 by a (C.sub.1 -C.sub.4)alkyl, or a 1H-indazol-7-yl group and pharmaceutically acceptable organic or inorganic salts thereof.Application in therapy.

    摘要翻译： 式（I）化合物其中R表示其中R 2为氢原子，（C 1 -C 4）烷氧基羰基，羧基，羧酸钠基团，-CH 2 OR 4基团 R4是氢原子或（C1-C4）烷基或（C1-C4）酰基，式-CONR5R6的酰胺基或-CN4R5基，R5是氢原子或（C1-C4） ）烷基，R6为氢原子，（C1-C4）烷基，羟基或（C1-C4）烷氧基，R3为（C1-C4）烷基，R1为氢原子 或（C1-C4）烷基，X表示硫原子，氧原子或亚甲基，n = 1或2，Ar表示被二（C1-C4）烷基取代的萘-1-基， 烷基氨基或6,7-二（C1-C4）烷氧基萘-1-基或在3个被（C1-C4）烷基取代的喹啉-8-基）或1,2,3 （C 1 -C 4）烷基取代的4-四氢喹啉-8-基，或1H-吲唑-7-基和药学上可接受的组 其酸性或无机盐。 应用于治疗。

    Method and device for implant deployment
    4.
    发明授权
    Method and device for implant deployment 有权
    用于植入物部署的方法和装置

    公开(公告)号：US08657832B2

    公开(公告)日：2014-02-25

    申请号：US12456602

    申请日：2009-06-18

    申请人： Thomas Purcell ,  William Reimels

    发明人： Thomas Purcell ,  William Reimels

    IPC分类号： A61B17/88

    CPC分类号： A61B17/8858 ,  A61B2017/00539

    摘要： A surgical implant insertion system for deployment and removal of an implant into a vertebral body. The system includes an actuation rod, an actuator handle coupled to the actuation rod, and an inserter locking tube disposed over the actuation rod and coupled to an inserter handle. Upon insertion of the implant into the vertebral body using the inserter handle, the actuator handle is turned causing the actuation rod to expand or compress the implant disposed at a distal end of the inserter locking tube.

    摘要翻译： 用于将植入物部署和移除到椎体中的手术植入物插入系统。 该系统包括致动杆，联接到致动杆的致动器手柄，以及设置在致动杆上并连接到插入器手柄的插入器锁定管。 当使用插入器手柄将植入物插入椎体时，致动器手柄被转动，致使致动杆膨胀或压缩设置在插入器锁定管的远端处的植入物。

    CURVILINEAR SPINAL ACCESS METHOD AND DEVICE
    5.
    发明申请
    CURVILINEAR SPINAL ACCESS METHOD AND DEVICE 审中-公开
    CURVILINEAR脊柱接触方法和装置

    公开(公告)号：US20120215229A1

    公开(公告)日：2012-08-23

    申请号：US13415186

    申请日：2012-03-08

    申请人： Javier Garcia-Bengochea ,  Jeffrey Allen Guyer ,  Thomas Purcell

    发明人： Javier Garcia-Bengochea ,  Jeffrey Allen Guyer ,  Thomas Purcell

    IPC分类号： A61B17/00

    CPC分类号： A61B17/34 ,  A61B17/02 ,  A61B17/1757 ,  A61B17/3417 ,  A61B17/3468 ,  A61B2017/0256 ,  A61B2017/3488 ,  A61F2/4611 ,  A61F2002/302 ,  A61F2230/0065

    摘要： A system for performing a procedure on a spine of a patient includes a curved tissue distractor, a curved housing, and an exterior channel. The curved tissue distractor includes a first distractor ramp and a second distractor ramp. The curved housing is configured to slide between the first and second distractor ramps. The curved housing includes a distal end, a proximal end, and an interior channel disposed between the distal end and the proximate end. The exterior channel is disposed on an outside surface of the curved housing and between the distal end and the proximal end. The curved housing is configured to slide between the first and second distractor ramps to provide access through the interior channel to the spine.

    摘要翻译： 用于在患者脊柱上执行手术的系统包括弯曲组织牵引器，弯曲壳体和外部通道。 弯曲组织牵引器包括第一牵引斜坡和第二牵引斜坡。 弯曲的壳体构造成在第一和第二牵引斜坡之间滑动。 弯曲的壳体包括远端，近端和设置在远端和近端之间的内部通道。 外部通道设置在弯曲壳体的外表面上，并且在远端和近端之间。 弯曲的壳体构造成在第一和第二牵引器斜面之间滑动以提供通过内部通道到达脊柱的通路。

    Variable angle spinal screw assembly
    6.
    发明授权
    Variable angle spinal screw assembly 有权
    可变角度脊椎螺钉组件

    公开(公告)号：US07377923B2

    公开(公告)日：2008-05-27

    申请号：US10848946

    申请日：2004-05-19

    申请人： Thomas Purcell ,  Don Hair ,  Tamas T. Frech

    发明人： Thomas Purcell ,  Don Hair ,  Tamas T. Frech

    IPC分类号： A61B17/70

    CPC分类号： A61B17/7037 ,  A61B17/7032 ,  A61B17/7038

    摘要： A spinal screw assembly providing an adjustable securement of a fixation rod across at least two vertebrae. The assembly includes a pedicle screw having a spherical head portion, a threaded shaft portion and a tool engagement surface in the head portion for use in driving the screw into a vertebrae. The head portion of the screw is positioned in a body member adjacent a curvilinear surface disposed about an aperture in the end of the body member such that the shaft portion of the screw extends therethrough and the curvilinear inner surface abuts and mates with the head portion of the screw so as to define a ball joint therewith. The body member additionally defines a pair of opposed parallel slots therein adapted to receive a portion of the fixation rod and a locking cap bears against the fixation rod to releasably secure the rod within the assembly.

    摘要翻译： 脊椎螺钉组件，其提供固定杆穿过至少两个椎骨的可调节固定。 组件包括具有球形头部，螺纹轴部分和头部中的工具接合表面的椎弓根螺钉，用于将螺钉驱动到椎骨中。 螺钉的头部位于身体部件中，邻近设置在主体部件的端部周围的孔的曲线表面，使得螺钉的轴部分穿过其延伸，并且曲线内表面邻接并与头部部分配合 螺钉，以便与其形成球形接头。 主体构件另外限定了一对相对的平行狭槽，其适于接收固定杆的一部分，并且锁定帽抵靠固定杆，以将杆可释放地固定在组件内。

    Retractor
    7.
    发明申请
    Retractor 有权
    牵引器

    公开(公告)号：US20080114208A1

    公开(公告)日：2008-05-15

    申请号：US11903896

    申请日：2007-09-24

    申请人： Clark Hutton ,  Thomas Purcell ,  Christopher M. Campbell

    发明人： Clark Hutton ,  Thomas Purcell ,  Christopher M. Campbell

    IPC分类号： A61B1/32

    CPC分类号： A61B17/0206 ,  A61B17/02 ,  A61B17/0293 ,  A61B90/50

    摘要： A retractor device for spearing the body tissue apart is provided. The retractor includes a housing configured to include a plurality of sections, wherein each section is configured to accommodate placement of at least one blade, a blade holding mechanism configured to secure the at least one blade within the housing, a translation mechanism configured to provide translation movement of at least one of the sections, and a rotation mechanism configured to provide rotation movement of at least one blade.

    摘要翻译： 提供了用于将身体组织分开的牵开器装置。 牵开器包括被构造成包括多个部分的壳体，其中每个部分被构造成适应至少一个叶片的放置，构造成将所述至少一个叶片固定在所述壳体内的叶片保持机构，配置成提供平移 至少一个部分的运动以及被配置为提供至少一个叶片的旋转运动的旋转机构。

    Adjustable occipital plate
    8.
    发明申请
    Adjustable occipital plate 有权
    可调枕枕板

    公开(公告)号：US20070118121A1

    公开(公告)日：2007-05-24

    申请号：US11544889

    申请日：2006-10-06

    申请人： Thomas Purcell ,  Frank Eismont

    发明人： Thomas Purcell ,  Frank Eismont

    IPC分类号： A61F2/30

    CPC分类号： A61B17/7055 ,  A61B17/7058

    摘要： Embodiments of an adjustable occipital plate is provided. The plate includes a fixation plate, at least one lateral rod configured to be coupled to the fixation plate, at least one sliding link configured to be coupled to the at least one lateral rod, and at least one posterior cervical rod configured to be coupled to the at least one sliding link using at least one rod connector.

    摘要翻译： 提供了一种可调枕枕板的实施例。 所述板包括固定板，构造成联接到固定板的至少一个侧向杆，至少一个滑动连杆，其构造成联接到所述至少一个侧向杆，以及至少一个后颈椎杆，其配置成联接到 所述至少一个滑动连杆使用至少一个杆连接器。

    Aircraft with foldable tail assembly
    9.
    发明申请
    Aircraft with foldable tail assembly 失效
    具有可折叠尾翼的飞机

    公开(公告)号：US20050242236A1

    公开(公告)日：2005-11-03

    申请号：US10833657

    申请日：2004-04-28

    申请人： Thomas Purcell

    发明人： Thomas Purcell

    IPC分类号： B64C3/56 ,  B64C5/02 ,  B64C5/06 ,  B64C5/12 ,  B64D5/00

    CPC分类号： B64C5/12 ,  B64C3/56 ,  B64C5/02 ,  B64C5/06

    摘要： A foldable tail assembly for an aircraft includes a stabilizer and a pair of right and left fins mounted with respect to the stabilizer so that the fins may lay flat over the stabilizer during periods when the aircraft is not flight-ready, and so that the fins may be erected above the stabilizer to form a triangular configuration when the aircraft is ready to fly.

    摘要翻译： 用于飞行器的可折叠尾部组件包括稳定器和相对于稳定器安装的一对左右翼片，使得在飞行器不能飞行准备的时期期间翅片可平放在稳定器上，并且使得翅片 可以竖立在稳定器上方，以在飞机准备飞行时形成三角形构型。

    Conveyor system with lifting mechanism
    10.
    发明授权
    Conveyor system with lifting mechanism 失效
    带升降机构的输送机系统

    公开(公告)号：US5985029A

    公开(公告)日：1999-11-16

    申请号：US745787

    申请日：1996-11-08

    申请人： Thomas Purcell

    发明人： Thomas Purcell

    IPC分类号： B23Q7/00 ,  B65G15/62 ,  B65G21/12 ,  B65G21/22 ,  B65G35/06 ,  H05K3/34 ,  H05K13/00 ,  B05B13/02 ,  B65B15/64

    CPC分类号： B65G21/12 ,  B65G15/62 ,  H05K13/0061 ,  B65G2201/02

    摘要： A conveyor system has a pair of elongated rails that support a pair of conveyors. A lifting mechanism is mounted to the rails for lifting the conveyor itself, or for lifting the circuit board at its edges near the conveyor. A stripping bar is provided in the rails for lifting stop tabs. The stripping bar and the lifting plates are moved by a cylinder that drives a camming plate along a direction of travel, while this motion is translated into motion transverse to the direction of travel.

    摘要翻译： 输送机系统具有支撑一对输送机的一对细长导轨。 提升机构安装到轨道上，用于提升输送机本身，或者用于在输送机附近的边缘抬起电路板。 在轨道上设置一个剥离杆，用于提升停止片。 剥离杆和提升板通过沿着行进方向驱动凸轮板的气缸移动，同时该运动被平移成横向于行进方向的运动。