Synthesis of bigraft copolymers based on grafted type peracid polymer
    5.
    发明授权
    Synthesis of bigraft copolymers based on grafted type peracid polymer 失效
    基于接枝型过酸聚合物的共聚物的合成

    公开(公告)号:US4927890A

    公开(公告)日:1990-05-22

    申请号:US248034

    申请日:1988-09-23

    IPC分类号: C08F285/00

    CPC分类号: C08F285/00

    摘要: The present invention relates to a method of synthesizing a bigraft compolymer based on grafted type peracid polymer, which comprises graft polymerizing a first ethylenically unsaturated monomer containing a carboxyl group onto a polymer substrate having a form of a membrane, particulate or tube; oxidizing the carboxyl groups of the resulting graft polymer into peracids; and then graft polymerizing a second ethylenically unsaturated monomer onto the grafted chain of the graft polymer through the decomposition of the peracid. Surface profile and morphology of the bigraft copolymer membrane product is also investigated by scanning electron microscopy and transmission electron microscopy respectively.

    摘要翻译: 本发明涉及一种基于接枝型过酸聚合物合成一种载体聚合物的方法,该方法包括将含有羧基的第一种烯属不饱和单体接枝聚合到具有膜,颗粒或管形式的聚合物基材上; 将所得接枝聚合物的羧基氧化成过酸; 然后通过过酸分解将第二种烯属不饱和单体接枝聚合到接枝聚合物的接枝链上。 还通过扫描电子显微镜和透射电子显微镜研究了大型共聚物膜产品的表面形貌和形貌。

    Multifunctional mixed micelle of graft and block copolymers and preparation thereof
    6.
    发明申请
    Multifunctional mixed micelle of graft and block copolymers and preparation thereof 审中-公开
    多功能混合胶束的接枝和嵌段共聚物及其制备

    公开(公告)号:US20080081075A1

    公开(公告)日:2008-04-03

    申请号:US11657468

    申请日:2007-01-25

    IPC分类号: A61K9/50 A61K9/16

    CPC分类号: A61K9/1075

    摘要: The present invention discloses a novel mixed micelle structure with a functional inner core and hydrophilic outer shells self-assembled from a graft macromolecule and one or more block copolymer, and preferably from a graft copolymer and two or more diblock copolymers. The micelle synthesized in the present invention has a size of about 50-200 nm, which can be used as a cancer diagnosis agent and a cancer drug delivery carrier.

    摘要翻译: 本发明公开了一种具有功能性内核和亲水性外壳的新型混合胶束结构,其由接枝高分子和一种或多种嵌段共聚物自组装,优选由接枝共聚物和两种或更多种二嵌段共聚物自组装。 本发明中合成的胶束具有约50-200nm的尺寸,可用作癌症诊断剂和癌症药物递送载体。

    Ferroelectric liquid crystal
    7.
    发明授权
    Ferroelectric liquid crystal 失效
    铁电液晶

    公开(公告)号:US5656197A

    公开(公告)日:1997-08-12

    申请号:US384027

    申请日:1995-02-06

    CPC分类号: C08G77/38 C09K19/408

    摘要: A polymer of the following formula: ##STR1## wherein m is an integer from 1 to 100; n is an integer from 0 to 3; each of X and Y, independently, is biphenyl, 1,4-phenylene, or halogen-substituted 1,4-phenylene; and Z is R, --O--(C.dbd.O)--R, or --(C.dbd.O)--O--R, wherein R is selected from (2R)-2-(C.sub.4-8 alkyl), (1S,2S)-1-halo-2-methyl-1-(C.sub.3-5 alkyl), (2S)-2-methyl-1-(C.sub.4-7 alkyl), (2S)-1-halo-2-methyl-3-propyl, and (2S)-3-halo-2-methyl-1-(C.sub.4-7 alkyl); anda monomer of the following formula:H.sub.2 C.dbd.CH.sub.2 CH.sub.2 --(OCH.sub.2 CH.sub.2).sub.n --O--X--(C.dbd.O)--O--Y--Zwherein n is an integer from 0 to 3; each of X and Y independently is biphenyl, 1,4-phenylene, or halogen-substituted 1,4-phenylene; and Z is R, --O--(C.dbd.O)--R, or --(C.dbd.O)--O--R, wherein R is selected from (2R)-2-(C.sub.4-8 alkyl), (1S,2S)-1-halo-2-methyl-1-(C.sub.3-5 alkyl), (2S)-2-methyl-1-(C.sub.5-7 alkyl), (2S)-1-halo-2-methyl-3-propyl, and (2S)-3-halo-2-methyl-1-(C.sub.4-7 alkyl).

    摘要翻译: 下式的聚合物:其中m是1至100的整数; n为0〜3的整数。 X和Y各自独立地是联苯基,1,4-亚苯基或卤素取代的1,4-亚苯基; 并且Z为R,-O-(C = O)-R或 - (C = O)-OR,其中R选自(2R)-2-(C 4-8烷基),(1S,2S) - 1-卤代-2-甲基-1-(C3-5烷基),(2S)-2-甲基-1-(C4-7烷基),(2S)-1-卤代-2-甲基-3-丙基, 和(2S)-3-卤代-2-甲基-1-(C 4-7烷基); 和下式的单体:H 2 C = CH 2 CH 2 - (OCH 2 CH 2)n-O-X-(C = O)-O-Y-Z其中n为0-3的整数; X和Y各自独立地是联苯基,1,4-亚苯基或卤素取代的1,4-亚苯基; 并且Z为R,-O-(C = O)-R或 - (C = O)-OR,其中R选自(2R)-2-(C 4-8烷基),(1S,2S) - 1-(2-甲基-1-(C 5-8烷基),(2S)-2-甲基-1-(C 5-7烷基),(2S)-1-卤代-2-甲基-3-丙基, 和(2S)-3-卤代-2-甲基-1-(C 4-7烷基)。

    Filter Medium For Leukocyte Removal
    9.
    发明申请
    Filter Medium For Leukocyte Removal 审中-公开
    过滤培养基去除白细胞

    公开(公告)号:US20120067821A1

    公开(公告)日:2012-03-22

    申请号:US13095976

    申请日:2011-04-28

    摘要: The present invention discloses a filter medium for removing leukocytes from a leukocyte-containing sample, comprising: a substrate and a first polymer. The first polymer forms cross-linked networks or polymer brushes on the substrate and comprising charged groups or latent charged groups to control the electrical characteristic of the first polymer. The surface of the substrate formed with the first polymer possesses a specific charge distribution having charged domains and zwitterionic non-charged domains.

    摘要翻译: 本发明公开了一种用于从含白细胞的样品中除去白细胞的过滤介质,包括:基底和第一聚合物。 第一聚合物在衬底上形成交联网络或聚合物刷,并且包括带电基团或潜电荷基团以控制第一聚合物的电特性。 用第一聚合物形成的基材的表面具有具有带电域和两性离子非带电畴的特定电荷分布。

    Biopolymer-bioengineered cell sheet construct
    10.
    发明申请
    Biopolymer-bioengineered cell sheet construct 审中-公开
    生物聚合物 - 生物工程化细胞片构建体

    公开(公告)号:US20080050423A1

    公开(公告)日:2008-02-28

    申请号:US11508241

    申请日:2006-08-23

    IPC分类号: A61K35/30 A61K9/70

    摘要: The present invention discloses a biopolymer-bioengineered human corneal endothelial cell (HCEC) sheet construct for reconstructing corneal endothelium in a patient. The construct includes a biopolymer carrier which is bioresorable and deformable; and a bioengineered cell sheet comprising a monolayer of interconnected HCECs with substantially uniform orientation, wherein the bioengineered cell sheet is attached to a surface of the carrier with apical surfaces of the HCECs facing said carrier.

    摘要翻译: 本发明公开了一种用于重建患者角膜内皮的生物聚合物 - 生物工程人角膜内皮细胞(HCEC)片构造物。 该构造体包括可生物切割和变形的生物聚合物载体; 以及生物工程化细胞片,其包含具有基本上均匀取向的相互连接的HCEC的单层,其中所述生物工程化细胞片被附接到所述载体的表面,所述HCEC的面向所述载体的顶端表面。