摘要:
An amphiphilic block copolymer and a pharmaceutical formulation comprising the same. The amphiphilic block copolymer comprises a poly(lactide) as a hydrophobic block and a poly(oxazoline) as a hydrophilic block.
摘要:
A block copolymer. The block copolymer has formula A-B-C, wherein A represents polyester, B represents polyamide, and C represents specific molecular groups or metal complexes. The invention also provides a nano micelle and drug carrier including the block copolymer, wherein the drug carrier is delivered by oral, transdermal administration, injection, or inhalation.
摘要:
A block copolymer. The block copolymer has formula A-B-C, wherein A represents polyester, B represents polyamide, and C represents specific molecular groups or metal complexes. The invention also provides a nano micelle and drug carrier including the block copolymer.
摘要:
A liquid testing system is provided, which includes a distribution module, a testing chip, a driving module and an image analyzing module. The distribution module is for providing a liquid. The testing chip receives the liquid from the distribution module. The driving module is connected to the testing chip and drives the testing chip to rotate, wherein the liquid flowing in the testing chip is actuated by centrifugal force. The image analyzing module produces and analyzes an image of the liquid in the testing chip.
摘要:
The present invention relates to a method of synthesizing a bigraft compolymer based on grafted type peracid polymer, which comprises graft polymerizing a first ethylenically unsaturated monomer containing a carboxyl group onto a polymer substrate having a form of a membrane, particulate or tube; oxidizing the carboxyl groups of the resulting graft polymer into peracids; and then graft polymerizing a second ethylenically unsaturated monomer onto the grafted chain of the graft polymer through the decomposition of the peracid. Surface profile and morphology of the bigraft copolymer membrane product is also investigated by scanning electron microscopy and transmission electron microscopy respectively.
摘要:
The present invention discloses a novel mixed micelle structure with a functional inner core and hydrophilic outer shells self-assembled from a graft macromolecule and one or more block copolymer, and preferably from a graft copolymer and two or more diblock copolymers. The micelle synthesized in the present invention has a size of about 50-200 nm, which can be used as a cancer diagnosis agent and a cancer drug delivery carrier.
摘要:
A polymer of the following formula: ##STR1## wherein m is an integer from 1 to 100; n is an integer from 0 to 3; each of X and Y, independently, is biphenyl, 1,4-phenylene, or halogen-substituted 1,4-phenylene; and Z is R, --O--(C.dbd.O)--R, or --(C.dbd.O)--O--R, wherein R is selected from (2R)-2-(C.sub.4-8 alkyl), (1S,2S)-1-halo-2-methyl-1-(C.sub.3-5 alkyl), (2S)-2-methyl-1-(C.sub.4-7 alkyl), (2S)-1-halo-2-methyl-3-propyl, and (2S)-3-halo-2-methyl-1-(C.sub.4-7 alkyl); anda monomer of the following formula:H.sub.2 C.dbd.CH.sub.2 CH.sub.2 --(OCH.sub.2 CH.sub.2).sub.n --O--X--(C.dbd.O)--O--Y--Zwherein n is an integer from 0 to 3; each of X and Y independently is biphenyl, 1,4-phenylene, or halogen-substituted 1,4-phenylene; and Z is R, --O--(C.dbd.O)--R, or --(C.dbd.O)--O--R, wherein R is selected from (2R)-2-(C.sub.4-8 alkyl), (1S,2S)-1-halo-2-methyl-1-(C.sub.3-5 alkyl), (2S)-2-methyl-1-(C.sub.5-7 alkyl), (2S)-1-halo-2-methyl-3-propyl, and (2S)-3-halo-2-methyl-1-(C.sub.4-7 alkyl).
摘要:
A chiral smectic liquid crystalline polymer having the following formula is disclosed: ##STR1## wherein m is an integer of about 40-80; n is an integer of about 1-12;R is ethylene or trimethylene;R' is methylene or oxyethylene;Ar is phenylene, chlorophenylene or ##STR2## wherein x is chlorine or hydrogen; and Ar' is phenylene or phenylenecarbonyl.
摘要:
The present invention discloses a filter medium for removing leukocytes from a leukocyte-containing sample, comprising: a substrate and a first polymer. The first polymer forms cross-linked networks or polymer brushes on the substrate and comprising charged groups or latent charged groups to control the electrical characteristic of the first polymer. The surface of the substrate formed with the first polymer possesses a specific charge distribution having charged domains and zwitterionic non-charged domains.
摘要:
The present invention discloses a biopolymer-bioengineered human corneal endothelial cell (HCEC) sheet construct for reconstructing corneal endothelium in a patient. The construct includes a biopolymer carrier which is bioresorable and deformable; and a bioengineered cell sheet comprising a monolayer of interconnected HCECs with substantially uniform orientation, wherein the bioengineered cell sheet is attached to a surface of the carrier with apical surfaces of the HCECs facing said carrier.