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1.发明申请公开(公告)号：US20060004306A1
公开(公告)日：2006-01-05
申请号：US11098015
申请日：2005-04-01
IPC分类号： A61H1/02
CPC分类号： A61B18/203 , A61B2017/00765 , A61B2018/00005 , A61B2018/00452 , A61B2018/0047 , A61B2018/00476 , A61B2018/2023 , A61B2018/20355 , A61H39/002 , A61H2201/10 , A61N1/00 , A61N2/00
摘要： Methods of treatment of tissue with electromagnetic radiation (EMR) to produce lattices of EMR-treated islets in the tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.
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2.发明申请公开(公告)号：US20060058712A1
公开(公告)日：2006-03-16
申请号：US11098000
申请日：2005-04-01
申请人： Gregory Altshuler , Ilya Yaroslavsky , Andrei Erofeev , David Tabatadze , Mikhail Smirnov , James Childs
发明人： Gregory Altshuler , Ilya Yaroslavsky , Andrei Erofeev , David Tabatadze , Mikhail Smirnov , James Childs
IPC分类号： A61H1/00
CPC分类号： A61B18/203 , A61B2017/00765 , A61B2018/00005 , A61B2018/00452 , A61B2018/0047 , A61B2018/00476 , A61B2018/2023 , A61B2018/20355 , A61H39/002 , A61H2201/10 , A61N1/00 , A61N2/00
摘要： Methods of treatment of tissue with electromagnetic radiation (EMR) to produce lattices of EMR-treated islets in the tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.
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3.发明申请公开(公告)号：US20060004347A1
公开(公告)日：2006-01-05
申请号：US11098036
申请日：2005-04-01
申请人： Gregory Altshuler , Ilya Yaroslavsky , Andrei Erofeev , David Tabatadze , Mikhail Smirnov , James Childs
发明人： Gregory Altshuler , Ilya Yaroslavsky , Andrei Erofeev , David Tabatadze , Mikhail Smirnov , James Childs
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B2017/00765 , A61B2018/00005 , A61B2018/00452 , A61B2018/0047 , A61B2018/00476 , A61B2018/2023 , A61B2018/20355 , A61H39/002 , A61H2201/10 , A61N1/00 , A61N2/00
摘要： Methods of treatment of tissue with electromagnetic radiation (EMR) to produce lattices of EMR-treated islets in the tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.
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4.发明申请Methods and products for producing lattices of EMR-treated islets in tissues, and uses therefor 审中-公开用于生产EMR处理的胰岛的组织中的晶格的方法和产品，并用于其中公开(公告)号：US20060020309A1
公开(公告)日：2006-01-26
申请号：US11097841
申请日：2005-04-01
IPC分类号： A61N5/06
CPC分类号： A61B18/203 , A61B2017/00765 , A61B2018/00005 , A61B2018/00452 , A61B2018/0047 , A61B2018/00476 , A61B2018/2023 , A61B2018/20355 , A61H39/002 , A61H2201/10 , A61N1/00 , A61N2/00
摘要： Methods of treatment of tissue with electromagnetic radiation (EMR) to produce lattices of EMR-treated islets in the tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.
摘要翻译： 公开了用电磁辐射（EMR）处理组织以在组织中产生EMR处理的胰岛的晶格的方法。 还公开了用于在组织中产生经EMR处理的胰岛的晶格的装置和系统，以及这种装置和系统的美容和医疗应用。
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5.发明申请公开(公告)号：US20090254076A1
公开(公告)日：2009-10-08
申请号：US12405931
申请日：2009-03-17
IPC分类号： A61B18/18
CPC分类号： A61B18/203 , A61B2018/00005 , A61B2018/00452 , A61B2018/00458 , A61B2018/0047 , A61B2018/00476 , A61B2090/065 , A61N5/0616 , A61N5/0617 , A61N5/062 , A61N2005/0643
摘要： Devices and methods of treatment of tissue, such as skin tissue, with electromagnetic radiation (EMR) are disclosed that employ local deformation of tissue in small areas. Devices and methods employing local deformation are used to produce fractional lattices of EMR-treated islets in tissue.
摘要翻译： 公开了利用电磁辐射（EMR）处理组织（例如皮肤组织）的装置和方法，其在小区域中采用局部组织变形。 使用局部变形的装置和方法用于在组织中产生EMR处理的胰岛的分格。
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6.发明申请Methods And Devices For Fractional Ablation Of Tissue For Substance Delivery 审中-公开用于物质输送组织的分数消融的方法和装置公开(公告)号：US20090069741A1
公开(公告)日：2009-03-12
申请号：US12206426
申请日：2008-09-08
申请人： Gregory B. Altshuler , Valery V. Tuchin , Ilya Yaroslavsky , James Childs , David Tabatadze , Andrei V. Erofeev
发明人： Gregory B. Altshuler , Valery V. Tuchin , Ilya Yaroslavsky , James Childs , David Tabatadze , Andrei V. Erofeev
CPC分类号： A61N1/327 , A61B5/441 , A61B18/203 , A61B2017/00747 , A61B2017/00765 , A61B2018/00005 , A61B2018/00452 , A61B2018/00458 , A61B2018/0047 , A61B2018/207 , A61H23/0236 , A61H23/0245 , A61H2201/0207 , A61H2201/0214 , A61H2201/0242 , A61H2201/025 , A61H2201/0278 , A61H2201/0285 , A61H2201/10 , A61H2201/105 , A61H2201/5079 , A61H2230/50 , A61N1/30 , A61N1/306 , A61N2/00 , A61N7/00 , A61N2007/0008
摘要： Methods and devices for ablating portions of a tissue volume with electromagnetic radiation (EMR) to produce lattices of EMR-treated ablation islets in the tissue are disclosed, including lattices of micro-holes, micro-grooves, and other structures. Also, methods and devices for using the ablated islets are disclosed, including to deliver chromophores, filler, drugs and other substances to the tissue volume.
摘要翻译： 公开了用于通过电磁辐射（EMR）烧蚀组织体积的部分以产生组织中EMR处理的消融岛的晶格的方法和装置，包括微孔，微槽和其它结构的晶格。 此外，公开了用于使用烧蚀的胰岛的方法和装置，包括将发色团，填充剂，药物和其它物质递送到组织体积。
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公开(公告)号：US20080294150A1
公开(公告)日：2008-11-27
申请号：US12102636
申请日：2008-04-14
CPC分类号： A61B18/203 , A61B2017/00747 , A61B2018/00452 , A61B2018/00458 , A61B2090/0436 , A61B2090/049 , A61N5/0616
摘要： Methods of treatment of tissue with electromagnetic radiation (“EMR”) to produce lattices of photoselective islets and other energy selective islets in tissue are disclosed. Also disclosed are devices and systems for producing lattices of EMR-treated islets in tissue, and cosmetic and medical applications of such devices and systems.
摘要翻译： 公开了用电磁辐射（“EMR”）处理组织以在组织中产生光选胰岛和其他能量选择性胰岛的晶格的方法。 还公开了用于在组织中产生经EMR处理的胰岛的晶格的装置和系统，以及这种装置和系统的美容和医疗应用。
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8.发明申请SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors 有权SMMR（小分子代谢物记者）用作体内葡萄糖生物传感器公开(公告)号：US20070110672A1
公开(公告)日：2007-05-17
申请号：US11475784
申请日：2006-06-26
申请人： Emile Bellott , Dongsheng Bu , James Childs , Christopher Lambert , Hubert Nienaber , Shirley Shi , Zhaolin Wang , Jerome Workman , Alex Zelenchuk
发明人： Emile Bellott , Dongsheng Bu , James Childs , Christopher Lambert , Hubert Nienaber , Shirley Shi , Zhaolin Wang , Jerome Workman , Alex Zelenchuk
CPC分类号： A61K49/0052 , A61K49/0021 , A61K49/0041 , C07F5/025 , C07F7/1804 , Y10T436/144444
摘要： Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used for monitoring glucose in vivo, advantageously on the skin.
摘要翻译： 描述了用作体内葡萄糖生物传感器，传感器组合物和使用方法的小分子代谢记录（SMMR）。 SMMR包括含有硼酸的呫吨，香豆素，喹诺酮和基于非花叶粉的小分子，其用于体内，有利地在皮肤上监测葡萄糖。
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