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    APPARATUS AND METHOD FOR RANGINGS AND NOISE REDUCTION OF LOW COHERENCE INTERFEROMETRY LCI AND OPTICAL COHERENCE TOMOGRAPHY OCT SIGNALS BY PARALLEL DETECTION OF SPECTRAL BANDS
    1.
    发明申请
    APPARATUS AND METHOD FOR RANGINGS AND NOISE REDUCTION OF LOW COHERENCE INTERFEROMETRY LCI AND OPTICAL COHERENCE TOMOGRAPHY OCT SIGNALS BY PARALLEL DETECTION OF SPECTRAL BANDS 有权
    通过并行检测光谱仪的低相干干涉LCI和光学相干TOMOGRAPHY OCT信号的范围和噪声降低的装置和方法

    公开(公告)号：US20080097709A1

    公开(公告)日：2008-04-24

    申请号：US11956129

    申请日：2007-12-13

    申请人： Johannes de Boer ,  Guillermo Tearney ,  Brett Bouma

    发明人： Johannes de Boer ,  Guillermo Tearney ,  Brett Bouma

    IPC分类号： G01R25/04

    CPC分类号： G01B9/02007 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02008 ,  G01B9/0201 ,  G01B9/02032 ,  G01B9/02044 ,  G01B9/02045 ,  G01B9/02079 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01N21/4795

    摘要： Apparatus and method for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (“LCI”) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source is split into N spectral bands. The N spectral bands are individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N. Each spectral band is detected by a separate photo detector and amplified. For each spectral band the signal is band pass filtered around the signal band by analog electronics and digitized, or, alternatively, the signal may be digitized and band pass filtered in software. As a consequence, the shot noise contribution to the signal is reduced by a factor equal to the number of spectral bands. The signal remains the same. The reduction of the shot noise increases the dynamic range and sensitivity of the system.

    摘要翻译： 通过检测并行的一组光谱带来增加光学相干断层扫描和低相干干涉测量（“LCI”）信号的灵敏度的装置和方法，每个频带是光频率的唯一组合。 LCI宽带宽源分为N个频谱带。 N个光谱带被单独检测和处理，以使信噪比增加N倍。每个光谱带由单独的光检测器检测并被放大。 对于每个光谱带，信号通过模拟电子装置在信号带周围进行带通滤波，并且被数字化，或者，信号可以被数字化并且在软件中进行带通滤波。 结果，对信号的散粒噪声贡献减小了等于光谱带数的因子。 信号保持不变。 喷射噪声的降低增加了系统的动态范围和灵敏度。

    Apparatus and method for ranging and noise reduction of low coherence interferometry lci and optical coherence tomography oct signals by parallel detection of spectral bands
    2.
    发明申请
    Apparatus and method for ranging and noise reduction of low coherence interferometry lci and optical coherence tomography oct signals by parallel detection of spectral bands 有权
    用于低相干干涉测量lci和光学相干断层扫描Oct信号的测距和降噪的装置和方法通过频谱带的并行检测

    公开(公告)号：US20050018201A1

    公开(公告)日：2005-01-27

    申请号：US10501276

    申请日：2003-01-24

    申请人： Johannes de Boer ,  Guillermo Tearney ,  Brett Bouma

    发明人： Johannes de Boer ,  Guillermo Tearney ,  Brett Bouma

    IPC分类号： G01B9/02 ,  G01N21/47

    CPC分类号： G01B9/02007 ,  A61B5/0059 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02008 ,  G01B9/0201 ,  G01B9/02032 ,  G01B9/02044 ,  G01B9/02045 ,  G01B9/02079 ,  G01B9/0209 ,  G01B9/02091 ,  G01B2290/45 ,  G01N21/4795

    摘要： Apparatus, method, logic arrangement and storage medium are provided for increasing the sensitivity in the detection of optical coherence tomography and low coherence interferometry (“LCI”) signals by detecting a parallel set of spectral bands, each band being a unique combination of optical frequencies. The LCI broad bandwidth source can be split into N spectral bands. The N spectral bands can be individually detected and processed to provide an increase in the signal-to-noise ratio by a factor of N. Each spectral band may be detected by a separate photo detector and amplified. For each spectral band, the signal can be band p3 filtered around the signal band by analog electronics and digitized, or, alternatively, the signal may be digitized and band pass filtered in software. As a consequence, the shot noise contribution to the signal is likely reduced by a factor equal to the number of spectral bands, while the signal amplitude can remain the same. The reduction of the shot noise increases the dynamic range and sensitivity of the system.

    摘要翻译： 提供装置，方法，逻辑布置和存储介质，用于通过检测光谱带的并行组来提高光学相干断层扫描和低相干干涉测量（“LCI”）信号的检测灵敏度，每个频带是光频率的唯一组合 。 LCI宽带宽源可以分为N个光谱带。 可以单独地检测和处理N个频谱带，以使信噪比增加N倍。每个频谱带可以由单独的光检测器检测并被放大。 对于每个频谱带，信号可以通过模拟电子装置在信号频带附近进行p3滤波，并且被数字化，或者，信号可以被数字化并且在软件中进行带通滤波。 结果，对信号的散粒噪声贡献可能降低等于光谱带数的因子，而信号幅度可以保持相同。 喷射噪声的降低增加了系统的动态范围和灵敏度。

    Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample
    3.
    发明申请
    Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample 有权
    用于通过同时照射和检测样品上的多个点来执行光学成像的装置，装置，内窥镜，导管和方法

    公开(公告)号：US20060114473A1

    公开(公告)日：2006-06-01

    申请号：US11288994

    申请日：2005-11-29

    申请人： Guillermo Tearney ,  Johannes de Boer ,  Brett Bouma

    发明人： Guillermo Tearney ,  Johannes de Boer ,  Brett Bouma

    IPC分类号： G01B9/02

    CPC分类号： G02B23/2469 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/6852 ,  G01B9/02001 ,  G01B9/02091 ,  G02B21/0032 ,  G02B21/0056 ,  G02B23/2453 ,  G02B23/26

    摘要： Devices, arrangements, endoscopes, catheters and methods adapted to propagate at least one electro-magnetic radiation are provided. In particular, a waveguide apparatus specifically configured may be utilized to split the electro-magnetic radiation into a plurality of beams that are intended to illuminate a biological sample, and impart a unique associated characteristic unto each of the beams. The beams may be intended to illuminate a biological sample at distinct locations, and impart a unique associated characteristic unto each of the beams. In addition, a control apparatus may be provided which is configured to control at least one of the fibers and which can be input to the fibers so as to modify the unique associated characteristics of the beams being propagated along the fibers, and thereby modify the characteristics of the distinct locations on the sample.

    摘要翻译： 提供了适于传播至少一个电磁辐射的装置，布置，内窥镜，导管和方法。 特别地，可以使用专门配置的波导装置将电磁辐射分割成旨在照射生物样品的多个光束，并且向每个光束赋予独特的相关特征。 光束可以用于在不同的位置照射生物样品，并且赋予每个光束唯一的相关特征。 此外，可以提供控制装置，其被配置为控制光纤中的至少一个并且可以输入到光纤，以便改变沿着光纤传播的光束的独特相关特性，从而改变特性 的样品上不同的位置。

    Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
    7.
    发明申请
    Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography 有权
    用于使用光学相干断层摄影确定样本中的至少一个位置的过程，系统和软件布置

    公开(公告)号：US20060039004A1

    公开(公告)日：2006-02-23

    申请号：US11200228

    申请日：2005-08-08

    申请人： Johannes de Boer ,  Boris Park

    发明人： Johannes de Boer ,  Boris Park

    IPC分类号： G01B9/02

    CPC分类号： A61B3/1225 ,  A61B3/1005 ,  A61B3/102 ,  G01B9/02004 ,  G01B9/02011 ,  G01B9/02044 ,  G01B9/02067 ,  G01B9/02068 ,  G01B9/02069 ,  G01B9/02083 ,  G01B9/02091 ,  G01B2290/45 ,  G01B2290/70 ,  G01N21/4795

    摘要： A system, process and software arrangement are provided to determine at least one position of at least one portion of a sample. In particular, information associated with the portion of the sample is obtained. Such portion may be associated with an interference signal that includes a first electromagnetic radiation received from the sample and a second electro-magnetic radiation received from a reference. In addition, depth information and/or lateral information of the portion of the sample, may be obtained. At least one weight function can be applied to the depth information and/or the lateral information so as to generate resulting information. Further, a surface position, a lateral position and/or a depth position of the portion of the sample may be ascertained based on the resulting information.

    摘要翻译： 提供系统，过程和软件布置以确定样品的至少一部分的至少一个位置。 特别地，获得与样本部分相关联的信息。 这样的部分可以与包括从样本接收的第一电磁辐射和从参考接收的第二电磁辐射的干扰信号相关联。 此外，可以获得样本部分的深度信息和/或横向信息。 至少一个权重函数可以应用于深度信息和/或横向信息，以便生成结果信息。 此外，可以基于所得到的信息来确定样品的该部分的表面位置，横向位置和/或深度位置。