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    High shear application in medical therapy
    2.
    发明授权
    High shear application in medical therapy 有权
    高剪切应用于医学治疗

    公开(公告)号：US09381138B2

    公开(公告)日：2016-07-05

    申请号：US14085420

    申请日：2013-11-20

    Applicant: H R D Corporation

    Inventor： Abbas Hassan ,  Aziz Hassan ,  Rayford G. Anthony

    IPC: A61J3/00 ,  B01F7/00 ,  B01F13/10 ,  A61M5/142 ,  A61K9/00

    CPC classification number: A61J3/00 ,  A61K9/0019 ,  A61M5/142 ,  B01F7/00766 ,  B01F7/008 ,  B01F13/1016

    Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 μm. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

    Abstract translation: 在本公开中，描述了一种方法，其中所述方法包括在高剪切装置中混合治疗气体或治疗液体或其组合和液体载体以产生分散体; 并将产生的分散体静脉内施用于患者; 其中所制备的分散体含有平均直径小于约1.5μm的治疗液体的治疗气体或液滴的纳米气泡。 在本公开中，还描述了一种系统，其中系统包括治疗气体源或治疗液体源或其组合; 液体载体源; 具有入口，出口，至少一个转子和由剪切间隔分开的至少一个定子的高剪切装置（HSD）; 以及构造成控制通过高剪切装置的流体的流速和停留时间的泵。

    Method of high shear comminution of solids
    4.
    发明授权
    Method of high shear comminution of solids 有权
    固体高剪切粉碎方法

    公开(公告)号：US09227196B2

    公开(公告)日：2016-01-05

    申请号：US13790733

    申请日：2013-03-08

    Applicant: H R D Corporation

    Inventor： Abbas Hassan ,  Aziz Hassan ,  Rayford G. Anthony ,  Gregory G. Borsinger

    IPC: B02C23/08 ,  C10G1/04 ,  C10G31/08

    CPC classification number: B02C23/08 ,  B02C23/18 ,  C10G1/045 ,  C10G31/08

    Abstract: Herein disclosed in a method comprising: shearing a feed comprising a solid component in a high shear device to produce a product, at least a portion of which comprises sheared solids; and separating at least some of the sheared solids from the product to produce a component-reduced product, wherein the solid component in the feed stream comprises a first particle density, and wherein the sheared solids in the product comprise a second particle density greater than the first particle density. In some embodiments, the solid component of the feed comprises gas trapped therein, and wherein at least a portion of said gas is released from the solid component upon shearing. Herein also is disclosed a method of comminuting solids in a feed stream comprising a solid component by processing the feed stream in a high shear device to produce a product stream comprising comminuted solids.

    Abstract translation: 本文公开的方法包括：在高剪切装置中剪切包含固体组分的进料以产生产品，其中至少一部分包括剪切固体; 以及从产品中分离出至少一些剪切的固体以产生组分还原产物，其中进料流中的固体组分包含第一颗粒密度，并且其中产物中的剪切固体包含大于 第一颗粒密度。 在一些实施方案中，进料的固体组分包含被捕获在其中的气体，并且其中至少一部分所述气体在剪切时从固体组分释放。 本文还公开了通过在高剪切装置中处理进料流以在包含固体组分的进料流中粉碎固体以产生包含粉碎固体的产物流的方法。

    ALGAE PROCESSING
    5.
    发明申请
    ALGAE PROCESSING 有权
    ALGAE加工

    公开(公告)号：US20140093951A1

    公开(公告)日：2014-04-03

    申请号：US14095211

    申请日：2013-12-03

    Applicant: H R D Corporation

    Inventor： Abbas HASSAN ,  Aziz Hassan ,  Rayford G. Anthony ,  Gregory G. Borsinger

    IPC: C12M1/00

    CPC classification number: C12M21/12 ,  C12M21/02 ,  C12M45/02 ,  C12N1/066 ,  C12N1/12 ,  Y02E50/17

    Abstract: A method for culturing algae comprising, forming an emulsion comprising a gaseous stream and a media utilizing a high shear device, wherein the emulsion comprises gas bubbles, and wherein the high shear device comprises at least one toothed rotor and at least one stator; introducing the emulsion into a bioreactor; and introducing an algae into the bioreactor for growing the algae culture. Additionally, a method for producing liquids from an algae culture, the method comprising forming an emulsion comprising a buffer and algal components, wherein the emulsion comprises algal component globules; separating algal hydrocarbons; and processing algal hydrocarbons to form liquid hydrocarbons. Additionally, a system for producing liquids from an algae culture comprising at least one high shear device.

    Abstract translation: 一种用于培养藻类的方法，包括：使用高剪切装置形成包含气流的乳液和介质，其中所述乳液包括气泡，并且其中所述高剪切装置包括至少一个齿形转子和至少一个定子; 将乳液引入生物反应器; 并将藻类引入用于生长藻类培养物的生物反应器中。 另外，一种从藻类培养物生产液体的方法，所述方法包括形成包含缓冲液和藻类成分的乳液，其中所述乳液包含藻类组分球; 分离藻类碳氢化合物; 并处理藻类碳氢化合物以形成液态烃。 另外，一种用于从包含至少一个高剪切装置的藻类培养物生产液体的系统。

    SYSTEM AND PROCESS FOR COAL LIQUEFACTION
    7.
    发明申请
    SYSTEM AND PROCESS FOR COAL LIQUEFACTION 审中-公开
    煤矿液化系统与工艺

    公开(公告)号：US20140209513A1

    公开(公告)日：2014-07-31

    申请号：US13790718

    申请日：2013-03-08

    Applicant: H R D CORPORATION

    Inventor： Abbas HASSAN ,  Aziz Hassan ,  Rayford G. Anthony ,  Gregory G. Borsinger

    IPC: C10B49/02 ,  F17D1/00

    CPC classification number: F17D1/00 ,  B01F7/00766 ,  B01F13/1016 ,  C10G1/065 ,  C10G1/083 ,  Y10T137/0318

    Abstract: Herein disclosed is a method for coal liquefaction comprising: supersaturating a hydrocarbonaceous liquid stream in a high shear device with a gas stream comprising hydrogen and optionally one or more C1-C6 hydrocarbons to form a supersaturated dispersion; and contacting the supersaturated dispersion with coal in the high shear device or in a coal liquefaction reactor to generate a product stream. In some embodiments, the method further comprises utilizing a conversion catalyst, wherein the catalyst is provided as a slurry, a fluidized bed, or a fixed bed. In some embodiments, the method further comprises feeding a conversion catalyst into the high shear device. In some embodiments, the method further comprises recycling at least a portion of an off gas from the reactor, recycling at least a portion of the product stream from the reactor, or both. Herein also disclosed is a system for coal liquefaction.

    Abstract translation: 本文公开了一种用于煤液化的方法，其包括：在高剪切装置中用含有氢气和任选的一种或多种C 1 -C 6烃的气流来过饱和烃类液体流以形成过饱和分散体; 并将过饱和分散体与高剪切装置中的煤或煤液化反应器中的煤接触以产生产物流。 在一些实施方案中，该方法还包括使用转化催化剂，其中催化剂作为浆料，流化床或固定床提供。 在一些实施方案中，该方法还包括将转化催化剂进料到高剪切装置中。 在一些实施方案中，该方法还包括将来自反应器的废气的至少一部分再循环至少一部分来自反应器的产物流或两者。 本文还公开了一种用于煤液化的系统。

    CONVERTING NATURAL GAS TO ORGANIC COMPOUNDS
    8.
    发明申请
    CONVERTING NATURAL GAS TO ORGANIC COMPOUNDS 审中-公开
    将天然气转化为有机化合物

    公开(公告)号：US20140128484A1

    公开(公告)日：2014-05-08

    申请号：US14071330

    申请日：2013-11-04

    Applicant: H R D Corporation

    Inventor： Abbas Hassan ,  Aziz Hassan ,  Rayford G. Anthony ,  Gregory G. Borsinger

    IPC: B01J23/89 ,  C07C2/84 ,  B01J19/28 ,  B01J27/24 ,  B01J19/00

    CPC classification number: B01J23/8993 ,  B01J8/009 ,  B01J8/025 ,  B01J8/10 ,  B01J12/007 ,  B01J19/0073 ,  B01J19/2495 ,  B01J19/28 ,  B01J23/8892 ,  B01J23/8986 ,  B01J27/24 ,  B01J2208/0053 ,  B01J2208/00911 ,  B01J2219/00159 ,  C01B3/40 ,  C01B2203/0233 ,  C01B2203/062 ,  C01B2203/1241 ,  C07C29/153 ,  C10G2/33 ,  C10G50/00 ,  Y02P20/149 ,  Y02P20/52 ,  C07C31/04

    Abstract: Herein disclosed is a catalyst composition for producing organic compounds comprising (a) a catalyst that promotes the oxidative coupling of methane (OCM) and a methane steam reforming (MSR) catalyst, wherein the catalyst composition causes oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (b) a catalyst that promotes syngas generation (SG) and a Fischer-Tropsch (FT) catalyst wherein the catalyst composition causes non-oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (c) a SG catalyst, a MSR catalyst, and a FT catalyst wherein the catalyst composition causes non-oxidative dehydrogenation to form reactive species and oligomerization of the reactive species to produce the organic compounds; or (d) a FT catalyst and a MSR catalyst wherein the catalyst composition causes reforming reactions and chain growing reactions to produce the organic compounds.

    Abstract translation: 本文公开了用于生产有机化合物的催化剂组合物，其包含（a）促进甲烷（OCM）和甲烷蒸汽重整（MSR）催化剂的氧化偶联的催化剂，其中催化剂组合物引起氧化脱氢形成反应性物质和低聚 产生有机化合物的反应物种; 或（b）促进合成气生成（SG）和费 - 托（FT）催化剂的催化剂，其中催化剂组合物引起非氧化脱氢形成反应性物质并使反应性物质低聚以产生有机化合物; 或（c）SG催化剂，MSR催化剂和FT催化剂，其中催化剂组合物引起非氧化脱氢形成活性物质并使反应性物质低聚以产生有机化合物; 或（d）FT催化剂和MSR催化剂，其中催化剂组合物引起重整反应和链增长反应以产生有机化合物。

    System and process for inhibitor injection
    9.
    发明授权
    System and process for inhibitor injection 失效
    抑制剂注射的系统和方法

    公开(公告)号：US08628232B2

    公开(公告)日：2014-01-14

    申请号：US13870734

    申请日：2013-04-25

    Applicant: H R D Corporation

    Inventor： Abbas Hassan ,  Ebrahim Bagherzadeh ,  Rayford G. Anthony ,  Gregory G. Borsinger ,  Aziz Hassan

    IPC: B01F3/04 ,  B01F7/00

    CPC classification number: C09K8/54 ,  B01F7/00766 ,  B01F13/1027 ,  B01F2215/0481 ,  E21B41/02 ,  Y10S516/923 ,  Y10S516/929

    Abstract: A method for introducing inhibitor into a fluid to be treated by forming a dispersion comprising droplets, particles, or gas bubbles of inhibitor dispersed in a continuous phase of a carrier, wherein forming the dispersion comprises subjecting a mixture of the inhibitor and the carrier to a shear rate of greater than about 20,000 s−1 in a high shear device comprising at least one generator comprising a rotor and a complementarily-shaped stator, wherein the rotor and the stator each comprise grooves, and wherein the grooves of the stator and the grooves of the rotor of each generator are disposed in alternating directions, and using at least a portion of the dispersion to inhibit corrosion.

    Abstract translation: 通过形成包含分散在载体的连续相中的抑制剂的液滴，颗粒或气泡的分散体将抑制剂引入待处理的流体的方法，其中形成所述分散体包括将所述抑制剂和载体的混合物 在包括至少一个包括转子和互补形状的定子的发电机的高剪切装置中，剪切速率大于约20,000s -1，其中转子和定子各自包括凹槽，并且其中定子和凹槽 每个发电机的转子设置在交替的方向上，并且使用至少一部分分散体来抑制腐蚀。

    Method of making alkylene glycols
    10.
    发明授权
    Method of making alkylene glycols 有权
    制备亚烷基二醇的方法

    公开(公告)号：US08480961B2

    公开(公告)日：2013-07-09

    申请号：US13631832

    申请日：2012-09-28

    Applicant: H R D Corporation

    Inventor： Abbas Hassan ,  Aziz Hassan ,  Rayford G. Anthony ,  Krishnan Viswanathan ,  Gregory G. Borsinger

    IPC: B01J14/00

    CPC classification number: B01F7/00766 ,  B01F13/1013 ,  B01F13/1016 ,  B01J8/025 ,  B01J8/20 ,  B01J19/0066 ,  B01J19/1806 ,  B01J2219/00006 ,  B01J2219/00779 ,  C07C29/106 ,  C08G65/2696 ,  C07C31/202 ,  C07C31/205 ,  C07C31/207

    Abstract: Herein disclosed is a system for hydrating an alkylene oxide that includes a high shear device configured to form a dispersion of an alkylene oxide and water, the high shear device comprising a rotor, a stator, and a catalytic surface, wherein the dispersion comprises gas bubbles with an average gas bubble diameter of less than about 5 μm; a pump configured for delivering a liquid stream to the high shear device; and a reactor coupled to the high shear device, and configured to receive the dispersion from the high shear device, wherein the alkylene oxide is hydrated in the reactor.

    Abstract translation: 本文公开了一种用于水合环氧烷的系统，其包括构造成形成环氧烷和水的分散体的高剪切装置，所述高剪切装置包括转子，定子和催化表面，其中所述分散体包括气泡 平均气泡直径小于约5um; 构造成用于将液体流输送到高剪切装置的泵; 和耦合到高剪切装置的反应器，并被配置为从高剪切装置接收分散体，其中烯化氧在反应器中水合。

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