公开(公告)号：US10830782B2

公开(公告)日：2020-11-10

申请号：US15476942

申请日：2017-03-31

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Kevin F. Peters

IPC: G01N21/00 ,  G01N35/10 ,  B01L3/02 ,  G01N35/00 ,  B01L3/00 ,  G01N21/51

Abstract: An assay-protocol-specific multi-channel fluid-dispenser cassette for an automated assay fluid dispensing system may include a structure with multiple fluid channels within the structure to contain and control respective assay fluids. Each fluid channels may have an outlet. A driver interface may be carried by the structure removably and mechanically engageable with a dispenser driver of a dispenser so that the dispenser driver can control the dispensing of fluids from the structure directly onto underlying reaction sites while each of the fluid channels remain as part of the structure. An assay-protocol-indicative cassette-type identifier may be formed in or attached to the structure and indicative of different assay protocols for all of the multiple fluid channels. The assay-protocol-cassette-type identifier may be readable by the cassette driver in response to the multi-channel fluid-dispenser cassette being removably connected to the dispenser.

公开(公告)号：US20170205438A1

公开(公告)日：2017-07-20

申请号：US15476942

申请日：2017-03-31

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Kevin F. Peters

IPC: G01N35/10 ,  G01N35/00 ,  B01L3/02 ,  B01L3/00

Abstract: An assay-protocol-specific multi-channel fluid-dispenser cassette for an automated assay fluid dispensing system may include a structure with multiple fluid channels within the structure to contain and control respective assay fluids. Each fluid channels may have an outlet. A driver interface may be carried by the structure removably and mechanically engageable with a dispenser driver of a dispenser so that the dispenser driver can control the dispensing of fluids from the structure directly onto underlying reaction sites while each of the fluid channels remain as part of the structure. An assay-protocol-indicative cassette-type identifier may be formed in or attached to the structure and indicative of different assay protocols for all of the multiple fluid channels. The assay-protocol-cassette-type identifier may be readable by the cassette driver in response to the multi-channel fluid-dispenser cassette being removably connected to the dispenser.

公开(公告)号：US20140193309A1

公开(公告)日：2014-07-10

申请号：US13736860

申请日：2013-01-08

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Matthew C. Still ,  Dennis R. Esterberg ,  Jeffrey A. Nielsen ,  Debora J. Thomas ,  Christie L. Dudenhoefer ,  Kevin F. Peters

IPC: B01L3/00

CPC classification number: B01L3/0268 ,  B01L9/54 ,  B01L2300/0816

Abstract: A liquid dispenser cassette includes a frame, dispense head assemblies, and a one-piece integrated slot extender. The frame defines openings. The dispense head assemblies are mounted on the frame. The dispense head assemblies include dispense head dies at least partially exposed through the corresponding openings. The dispense head dies defines top slots. The slot extender is mounted on the dispense head assemblies. The slot extender has reservoirs defining drain openings mated to the corresponding top slots.

Abstract translation: 液体分配器盒包括框架，分配头组件和单件集成插槽延伸器。 框架定义开口。 分配头组件安装在框架上。 分配头组件包括至少部分地通过相应的开口露出的分配头模具。 分配头模具定义顶部槽。 插槽延伸器安装在分配头组件上。 狭缝延伸器具有限定排出开口的储存器，排出口与相应的顶部狭槽配合。

公开(公告)号：US20130143328A1

公开(公告)日：2013-06-06

申请号：US13754708

申请日：2013-01-30

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Kevin F. Peters

IPC: G01N35/10

CPC classification number: G01N35/1002 ,  B01L3/0268 ,  B01L3/527 ,  B01L3/545 ,  B01L2200/04 ,  B01L2200/061 ,  B01L2200/0642 ,  B01L2200/143 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/022 ,  B01L2400/02 ,  B01L2400/0442 ,  G01N35/00732 ,  G01N35/0092 ,  G01N35/1016 ,  G01N2021/513 ,  G01N2035/00425 ,  G01N2035/00831 ,  G01N2035/00891 ,  Y10T436/11

Abstract: An automated assay fluid dispensing system includes a database that associates assay protocols with assay procedures, the procedures including a first assay procedure specifying dissimilar first and second channel procedures for driving first and second channels of a fluid-dispenser cassette. The system includes a controller with a procedure selector to select or to assist a human to select an assay procedure from the database to be executed in an assay run. The controller also includes a cassette driver to drive the cassette to dispense fluids automatically to multiple sites during the assay run so that fluids in the first and second channels are dispensed in accordance with the dissimilar first and second channel procedures. The system includes a cassette interface to engage the cassette so that the controller can drive it to implement the assay run.

Abstract translation: 自动化测定流体分配系统包括将测定方案与测定程序相关联的数据库，该方法包括指定用于驱动流体分配器盒的第一和第二通道的不同的第一和第二通道程序的第一测定程序。 该系统包括具有过程选择器的控制器，以选择或辅助人类从数据库中选择要在分析运行中执行的测定程序。 控制器还包括盒式驱动器，以在分析运行期间驱动盒子以自动分配流体到多个位置，使得根据不同的第一和第二信道程序来分配第一和第二信道中的流体。 该系统包括一个盒式磁带接口，用于接合盒式磁带，使得控制器可以驱动它来实现测定运行。