公开(公告)号：US11474119B2

公开(公告)日：2022-10-18

申请号：US16624376

申请日：2018-03-30

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Takahiro Kumagai ,  Takenori Okusa

IPC: G01N35/00 ,  G01N35/04

Abstract: There is provided an automatic analysis device that can appropriately sort and discard expendable items. The automatic analysis device includes a common transport mechanism that transports a plurality of types of expendable items by common mechanism, a plurality of transport paths that is provided separately from the common transport mechanism, a type determination portion that determines the type of expendable item being transported by the common transport mechanism. The automatic analysis device controls to select one of a plurality of transport paths according to a determination result of the type determination portion and to transport the expendable items transported from the common transport mechanism via the selected transport path.

公开(公告)号：US11161118B2

公开(公告)日：2021-11-02

申请号：US16477535

申请日：2018-02-15

Applicant: Hitachi High-Technologies Corporation

Inventor： Hiroki Fujita ,  Toshiharu Suzuki ,  Takenori Okusa ,  Shunsuke Sasaki ,  Yoshihiro Yamashita ,  Kenta Imai

IPC: B01L3/00 ,  G01N35/00 ,  G01N35/10

Abstract: The mixing of reagents with each other in the reagent storage flow paths of an automatic analyzer is suppressed before and after exchange of the reagents, which are capable of being replenished without stopping analysis. An exchangeable reagent container that accommodates a reagent is connected to a reagent storage flow path that stores a portion of the reagent. The reagent storage flow path has first and second flow paths in which the second flow path is branched from the first flow path. A reagent syringe applies a negative or a positive pressure to the first and second flow paths; and a valve controls the flow path through which the reagent is sent. As a result, the reagent supplied to a measurement portion at a predetermined timing is switched from the reagent container to the reagent storage flow path wherein the reagent can be supplied without stopping analysis.

公开(公告)号：US11340241B2

公开(公告)日：2022-05-24

申请号：US16477219

申请日：2018-01-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Shunsuke Sasaki ,  Takenori Okusa ,  Yoshihiro Yamashita ,  Hiroki Fujita ,  Kenta Imai ,  Toshiharu Suzuki

IPC: G01N35/00 ,  B01L9/00 ,  G01N35/04

Abstract: An automated analyzer capable of continuously performing supply of consumables is realized while continuing measurement is performed, by a simple and small amount of mechanism. An automated analyzer includes a unit that executes processing necessary for sample analysis; a consumable supply unit that supplies consumables necessary for the sample analysis to the unit; and a control device that controls operations of the unit and the consumable supply unit, in which the consumable supply unit includes a consumable container holding portion that holds a consumable storage container in which consumables is aligned and accommodated, a preliminary storage portion that temporarily holds the consumables taken out from the consumable storage container, and a transport mechanism that transports the consumables to the unit, and in which the control device transports and stores at least a portion of the consumables taken out from the consumable storage container in the preliminary storage portion.

公开(公告)号：US08747744B2

公开(公告)日：2014-06-10

申请号：US13738555

申请日：2013-01-10

Applicant: Hitachi High-Technologies Corporation

Inventor： Hironobu Yamakawa ,  Yoichi Aruga ,  Takenori Okusa ,  Taisaku Seino

IPC: G01N33/50 ,  B01F13/02 ,  G01N35/02 ,  G01L9/00 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01L9/00 ,  B01F13/0272 ,  B01L3/508 ,  B01L3/5085 ,  B01L99/00 ,  B01L2300/0636 ,  B01L2300/0822 ,  B01L2300/0829 ,  B08B9/035 ,  B08B9/0817 ,  G01L9/0041 ,  G01N33/50 ,  G01N35/025 ,  G01N2035/00544 ,  G01N2035/0437 ,  Y10T436/2575

Abstract: An automatic chemical analyzer in which a reaction solution is stirred by air ejected from an air ejection hole placed above a reaction container. The reaction region can be washed and cleaned sufficiently without causing damage, such as exfoliation of a coating reagent. A reaction container disk is provided with a pore and a pressure detector connected with the pore. Before and after the stirring operation, the ejection hole (nozzle) ejecting air is moved and the output value of the pressure detector is compared with a previously measured normal value. With a discharge pipe and a suction pipe inserted to the opening of the reaction container to be close to both ends of the opening and the side wall of the container, the reaction region at the bottom of the container is washed by continuous discharge and suction of cleaning fluid.

Abstract translation: 一种自动化学分析仪，其中反应溶液被从放置在反应容器上方的空气喷射孔喷出的空气搅拌。 可以充分洗涤和清洁反应区域而不会引起诸如涂层试剂剥落的损伤。 反应容器盘设置有孔和与孔相连的压力检测器。 在搅拌操作之前和之后，移动喷射孔（喷嘴）喷射空气，并将压力检测器的输出值与先前测量的正常值进行比较。 通过将排出管和吸入管插入反应容器的开口以接近容器的开口和侧壁的两端，容器底部的反应区域通过连续排出和抽吸 清洗液

公开(公告)号：US12163971B2

公开(公告)日：2024-12-10

申请号：US16644622

申请日：2018-08-22

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Taichiro Yamashita ,  Takenori Okusa ,  Susumu Sakairi

IPC: G01N35/04 ,  G01N35/00

Abstract: A driving mechanism for moving a vessel having a disposal box placed thereon in a front-rear direction the same as an opening/closing direction of a drawer is provided lower than a bottom surface of the vessel. A first rail extended in a movement direction of an operating unit, a second rail extended in a movement direction of the vessel provided in the drawer, and toothed pulleys for rotating a toothed belt within a horizontal plane are arranged. The first rail, the second rail, and the toothed belt are placed side by side without overlapping with each other in a vertical direction. As a result, the operation of taking out the disposal box in which used sample dispensing tips or reaction vessels are accumulated is simple.

公开(公告)号：US10890594B2

公开(公告)日：2021-01-12

申请号：US15577863

申请日：2016-04-28

Applicant: Hitachi High-Technologies Corporation

Inventor： Yu Niiyama ,  Takenori Okusa

IPC: G01N35/10 ,  G01N35/04 ,  G01N35/00

Abstract: The automated analyzer equalizes the temperature inside a reagent container storage apparatus. The automated analyzer is provided with a reagent container storage apparatus that cools a reagent container, the reagent container storage apparatus being provided with: a reagent storage chamber for storing the reagent container, the reagent storage chamber having at least one of the bottom surface and the side surface thereof cooled by a first cooling source; and a transfer member which is arranged to cover the reagent container stored in the reagent storage chamber, and which is thermally connected to the reagent storage chamber.

公开(公告)号：US09846170B2

公开(公告)日：2017-12-19

申请号：US14373368

申请日：2012-12-20

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Takenori Okusa ,  Kazuhiro Nakamura ,  Yoshihiro Suzuki

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/00029 ,  G01N35/00663 ,  G01N35/0092 ,  G01N35/04 ,  G01N2035/00673 ,  G01N2035/0443 ,  G01N2035/0455 ,  G01N2035/0462

Abstract: To provide an automated analyzer adapted for accommodating a larger number of reagent cassettes to meet calls for increases in analytical throughput and in the number of analytical items, and thus using the accommodated reagent cassettes more efficiently. An automated analyzer body 100 includes a main reagent buffer 4 for storing a plurality of reagent cassettes each containing a reagent used for analysis and a subsidiary reagent buffer 12. A reagent cassette transfer 11 transfers the reagent cassettes from the main reagent buffer to the subsidiary reagent buffer, and vice versa. A control unit 200 operates so that when a reagent cassette that is not set in the main reagent buffer is to be used for an assigned analysis, the reagent cassette for the assigned analysis is transferred from the subsidiary reagent buffer to the main reagent buffer.

公开(公告)号：US11525837B2

公开(公告)日：2022-12-13

申请号：US16637808

申请日：2018-07-26

Applicant: Hitachi High-Technologies Corporation

Inventor： Yoshihiro Yamashita ,  Takenori Okusa ,  Shunsuke Sasaki

IPC: G01N35/00 ,  G01N33/543 ,  G01N35/02

Abstract: An object is to provide an automatic analyzer that prevents an effect of various environmental changes on an equilibrium state of an immunological binding reaction. An automatic analyzer of an embodiment of the invention includes a B/F separation unit that executes a B/F separation step separating an unreacted component and a reacted component from a liquid in which a sample and a reagent are reacted, a detection unit that detects a reacted component in the liquid after the B/F separation step, and a temperature maintaining unit that maintains the B/F separation unit and the detection unit in substantially the same temperature environment.

公开(公告)号：US11300488B2

公开(公告)日：2022-04-12

申请号：US16480337

申请日：2018-01-18

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Koki Yokoyama ,  Nobuyuki Isoshima ,  Takenori Okusa ,  Shigeyuki Sasaki ,  Michiharu Watanabe

IPC: G01N1/44 ,  B01L7/00 ,  B01L9/06 ,  G01N35/02 ,  G01N35/00

Abstract: Temperature uniformity of a reaction liquid in a plurality of reaction containers of an automatic analysis device is maintained by a heat block. A strip-shaped heater heats the heat block, and is wound and attached on an outer circumference of the heat block so that both end regions of the strip-shaped heater are adjacent to each other. The strip-shaped heater includes a heat generating resistor that is heated by applying an electric current, an insulating film sandwiching the heat generating resistor, and first and second electrical feed lines that are attached to both end portions of the heat generating resistor and supply power to the heat generating resistor. The width of the heat generating resistor in both end regions of the strip-shaped heater is formed to be narrower than the width of the heat generating resistor in the other region thereof.

公开(公告)号：US11215629B2

公开(公告)日：2022-01-04

申请号：US16483459

申请日：2018-01-24

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Yoshihiro Kabe ,  Takenori Okusa

IPC: G01N35/10 ,  G01N35/04

Abstract: An automated analyzer includes a container installation portion in which a container, such as a reagent container, has a protrusion and an openable and closable lid. A lid opening and closing mechanism opens and closes the lid and includes an arm portion having an arm and a horizontal driving portion which moves the arm in a first horizontal direction. The arm includes a protrusion contacting portion that includes a first surface having an angle greater than 0 degrees and less than 90 degrees when the horizontal surface is set as 0 degrees. The lid opening and closing mechanism portion opens the lid by moving the arm in the first horizontal direction, contacting the lid protrusion on the first surface of the protrusion contacting portion, and then moving the lid protrusion along a shape of the first surface in a vertical direction, until the lid is opened.