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公开(公告)号：US07237691B2
公开(公告)日：2007-07-03
申请号：US11311601
申请日：2005-12-19
IPC分类号： B65D35/28
CPC分类号： B67D1/0037 , B65D77/30 , B65D2231/004 , B67D1/0078 , B67D1/0079 , B67D1/0462 , B67D1/0801 , B67D1/1286 , B67D3/041 , B67D2001/0814 , B67D2210/0006
摘要： A flexible bag having expansible and collapsible cells can be used in a liquid dispenser. A rigid manifold, and in one instance a rigid frame is provided in the bag to keep passages open in use and to isolate one of the cells from the remaining cells. The manifold is capable of altering the volume of one of the cells so that the same bag can be used in different applications.
摘要翻译： 具有可膨胀和可折叠细胞的柔性袋可用于液体分配器。 刚性歧管，并且在一个实例中，刚性框架设置在袋中以在使用中保持通道开放并且将其中一个电池与剩余的电池隔离。 歧管能够改变其中一个电池的体积，使得相同的袋可以在不同的应用中使用。
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公开(公告)号：US07007824B2
公开(公告)日：2006-03-07
申请号：US10640935
申请日：2003-08-14
IPC分类号： B65D35/28
CPC分类号： B67D1/0037 , B65D77/30 , B65D2231/004 , B67D1/0078 , B67D1/0079 , B67D1/0462 , B67D1/0801 , B67D1/1286 , B67D3/041 , B67D2001/0814 , B67D2210/0006
摘要： A liquid dispenser uses a flexible bag having expansible and collapsible cells. A rigid manifold, and in one instance a rigid frame is provided in the bag to keep passages open in use and to isolate one of the cells from the remaining cells. The dispenser employs an efficient and quiet air pressure operating system. In one application, a concentrated drink mix may be held in a reservoir and diluted within other cells in the bag for dispensing to a cup or the like. A valve system allows for the particulates in the liquid without compromising the function of the valve.
摘要翻译： 液体分配器使用具有可膨胀和可折叠单元的柔性袋。 刚性歧管，并且在一个实例中，刚性框架设置在袋中以在使用中保持通道开放并且将其中一个电池与剩余的电池隔离。 分配器采用高效安静的气压操作系统。 在一个应用中，浓缩饮料混合物可以保持在储存器中并在袋中的其它细胞内稀释以分配到杯子等中。 阀系统允许液体中的微粒而不损害阀的功能。
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公开(公告)号：US6162206A
公开(公告)日：2000-12-19
申请号：US996642
申请日：1997-12-23
申请人： Algirdas J. Bindokas , Birendra K. Lal , Ray Brausam , Thomas A. Stonis , Steven C. Jepson , Michael W. Scharf , David V. Bacehowski , Michael T. K. Ling , Hugh M. Forman , Daniel J. Rudolph
发明人： Algirdas J. Bindokas , Birendra K. Lal , Ray Brausam , Thomas A. Stonis , Steven C. Jepson , Michael W. Scharf , David V. Bacehowski , Michael T. K. Ling , Hugh M. Forman , Daniel J. Rudolph
CPC分类号： A61J1/2096 , A61J1/10 , A61J1/1406 , A61J1/1475 , A61J1/201 , Y10S604/905
摘要： A resealable access site (10) is provided for allowing a cannula (18) multiple accesses to an internal cavity (35) defined by a container (12). The access site (10) includes a first conduit (28) defining a passageway (29) forming a fluid path to the cavity within the container. Sealingly attached to the conduit (28) is a housing (26) with a lower portion (26a) and a lower flange (68) attached to a lower end of the lower portion and extending radially inward from the lower portion. A septum (24) is disposed and compressed within the lower portion, with the septum defining an opening (46) extending upward through at least a portion of the septum. The opening (46) is sized for insertion of the cannula (18) through the septum (24) with the septum sealing about the exterior of the cannula. The septum (24) is maintained in the housing by the support provided by the opposing flange (68) and conduit (28).
摘要翻译： 提供可重新密封的进入位置（10），用于允许套管（18）对由容器（12）限定的内部腔（35）进行多次通路。 进入位置（10）包括限定通道（29）的第一导管（28），该通道形成到容器内的空腔的流体路径。 密封地连接到导管（28）的是壳体（26），其具有下部（26a）和下凸缘（68），下凸缘（68）附接到下部的下端并从下部径向向内延伸。 隔膜（24）在下部设置并压缩，隔膜限定向上延伸穿过隔膜的至少一部分的开口（46）。 开口（46）的尺寸适于插入套管（18）穿过隔膜（24），隔膜围绕套管的外部密封。 通过由相对的凸缘（68）和导管（28）提供的支撑将隔垫（24）保持在壳体中。
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4.发明授权Multilayer gas-permeable container for the culture of adherent and non-adherent cells 失效用于粘附和非贴壁细胞培养的多层透气容器公开(公告)号：US06297046B1
公开(公告)日：2001-10-02
申请号：US08330717
申请日：1994-10-28
申请人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
发明人： Sidney T. Smith , David V. Bacehowski , William Kolanko , Larry Rosenbaum , Stephen L. Smith , James G. Bender , Lecon Woo , Michael T. K. Ling
IPC分类号： C12M306
摘要： A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inches to about 0.0010 inches and, a second layer (14) adhered to the first layer (12) composed of a polyolefin having a thickness within the range of 0.004 inches to about 0.015 inches.
摘要翻译： 一种适用于形成细胞培养容器（20）的多层柔性透气膜（10），所述膜（10）包括由厚度在0.0001英寸范围内的聚苯乙烯构成的第一层（12） 至约0.0010英寸，以及粘附到由厚度在0.004英寸至约0.015英寸范围内的聚烯烃构成的第一层（12）的第二层（14）。
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5.发明授权Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system 失效具有粘结和预卷绕脐带系统的离心处理设备的可旋转碗组件
公开(公告)号：US4459169A
公开(公告)日：1984-07-10
申请号：US478113
申请日：1983-03-23
CPC分类号： B04B5/0442 , B29C53/14 , B29C65/4895 , B29C66/5227 , A61M1/36 , B04B2005/045 , B04B2005/0492 , B29L2023/00 , B29L2031/601 , Y10T156/1002 , Y10T156/1043
摘要： A rotatable processing bowl assembly adapted for mounting in a centrifuge includes an umbilical tubing system formed of a plurality of individual flexible tubes each of which communicates with the processing bowl. Each tube has an exterior wall and includes a first portion extending adjacently from the bowl and a second portion which is spaced from the bowl. The exterior walls of the tubes are bonded together along their first portions so that the joined exterior walls collectively define the outer periphery of the tubing system along the first portions of the tubes. Preferably, the tubes are also wound to form a predetermined helical pattern along their first portions. This arrangement enhances the tubing system's durability and resistance to fatigue along the bonded together first portions, particularly at higher rotational speeds, and permits direct, facile connection of the free and unattached second portions with external apparatus.
摘要翻译： 适于安装在离心机中的可旋转处理碗组件包括由多个单独的柔性管形成的脐带管系统，每个柔性管各自与加工碗连通。 每个管具有外壁并且包括从碗相邻延伸的第一部分和与碗间隔开的第二部分。 管的外壁沿其第一部分结合在一起，使得连接的外壁沿着管的第一部分共同限定管道系统的外周。 优选地，管也被缠绕以沿其第一部分形成预定的螺旋形图案。 这种布置提高了管道系统的耐久性和耐疲劳性，特别是在更高的转速下，并且允许将自由和未附接的第二部分与外部设备直接，容易地连接。
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6.发明授权Coextruded silicone-containing tubing having long term frictional lubrication properties 失效具有长期摩擦润滑性能的共挤出含硅酮管
公开(公告)号：US4299256A
公开(公告)日：1981-11-10
申请号：US194205
申请日：1980-10-06
CPC分类号： B29C47/0023 , B04B5/0442 , B29C47/065 , B29C47/26 , F16L11/04 , B04B2005/0492 , Y10S138/07 , Y10T428/1379 , Y10T428/31663 , Y10T428/31667
摘要： Flexible coextruded tubing having an outer portion (14) of polyvinyl chloride plastic containing a minor amount of intimately mixed silicone oil and having an inner portion (12) of plastic free of silicone oil.
摘要翻译： 柔性共挤出管，其具有含有少量紧密混合的硅油的聚氯乙烯塑料的外部部分（14），并且具有不含硅油的塑料的内部部分（12）。
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公开(公告)号：US4196088A
公开(公告)日：1980-04-01
申请号：US838706
申请日：1977-10-03
CPC分类号： A61J1/05 , B04B5/0428 , B65D37/00 , B04B2005/045
摘要： A connection of a tubular member with a flexible plastic container includes an aperture in the wall of the flexible plastic container. The tubular member is positioned adjacent the aperture, with the axis of the tubular member being generally parallel to the plane of the aperture. Lateral apertures are defined in the tubular member in communication with the aperture, and an outer wall sealingly surrounds the portion of the tubular member adjacent the aperture to prevent leakage therefrom.
摘要翻译： 管状构件与柔性塑料容器的连接在柔性塑料容器的壁中包括孔。 管状构件邻近孔定位，管状构件的轴线大致平行于孔的平面。 横向孔口限定在与孔连通的管状构件中，并且外壁密封地围绕邻近孔的管状构件的部分以防止其从其中泄漏。
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公开(公告)号：US5571068A
公开(公告)日：1996-11-05
申请号：US277706
申请日：1994-07-20
CPC分类号： F04B43/10 , B04B1/00 , B04B5/0428 , B04B5/0442 , C07K16/30 , F04B9/02 , B04B2005/045 , B04B2005/0464
摘要： A blood component separating device comprises a centrifuge bowl adapted for rotation about its axis in a centrifuge. The bowl defines an outer arcuate wall plus an inner circumferential wall, spaced from the outer wall, to define a arcuate slot adapted for receiving blood components. Access tubing is adapted for communication with the slot. Preferably, an elongated, flexible, collapsible inner liner is provided in the slot. Individual access tubing also may communicate with an elongated container interior between the ends of the elongated, collapsible container. Furthermore, a portion of the slot may define the shape of an outwardly extending spiral, to provide an increasing gravitational field upon fluids therein as the fluid moves along the slot.
摘要翻译： 血液成分分离装置包括适于在离心机中围绕其轴旋转的离心机碗。 碗定义了外弧形壁加上与外壁间隔开的内周壁，以限定适于接收血液成分的弧形槽。 接入管适用于与槽连通。 优选地，在狭槽中设置细长的，柔性的可折叠内衬。 单独的进入管也可以与细长的可收缩容器的端部之间的细长的容器内部连通。 此外，槽的一部分可以限定向外延伸的螺旋的形状，以在流体沿着狭槽移动时为其中的流体提供增加的重力场。
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公开(公告)号：US4820297A
公开(公告)日：1989-04-11
申请号：US940816
申请日：1986-12-12
申请人： Stephen B. Kaufman , Robert Patterson , David V. Bacehowski , Arnold C. Bilstad , Patrick N. Huehls
发明人： Stephen B. Kaufman , Robert Patterson , David V. Bacehowski , Arnold C. Bilstad , Patrick N. Huehls
摘要： A fluid delivery system has a container with an integrally attached sample cell. A selected fluid can be accumulated in the container. The sample cell can be filled with part of the fluid in the container and then isolated from the container by heat or dielectric sealing. The fluid in the sample cell can be brought into contact with selected test reagents. The test reagents can provide a visual indicia of the presence of selected characteristics in the fluid.
摘要翻译： 流体输送系统具有带有整体连接的样品池的容器。 所选择的流体可以积聚在容器中。 样品池可以在容器中填充一部分流体，然后通过加热或电介质密封与容器隔离。 样品池中的流体可以与选定的试剂接触。 测试试剂可以提供在流体中存在所选特征的视觉标记。
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10.发明授权Rotatable bowl assembly for centrifugal processing apparatus having a bonded and prewound umbilical system 失效具有粘结和预卷绕脐带系统的离心处理设备的可旋转碗组件
公开(公告)号：US4389207A
公开(公告)日：1983-06-21
申请号：US244398
申请日：1981-03-16
CPC分类号： B04B5/0442 , B04B2005/045 , B04B2005/0492
摘要： A rotatable processing bowl assembly adapted for mounting in a centrifuge includes an umbilical tubing system formed of a plurality of individual flexible tubes each of which communicates with the processing bowl. Each tube has an exterior wall and includes a first portion extending adjacently from the bowl and a second portion which is spaced from the bowl. The exterior walls of the tubes are bonded together along their first portions so that the joined exterior walls collectively define the outer periphery of the tubing system along the first portions of the tubes. Preferably, the tubes are also wound to form a predetermined helical pattern along their first portions. This arrangement enhances the tubing system's durability and resistance to fatigue along the bonded together first portions, particularly at higher rotational speeds, and permits direct, facile connection of the free and unattached second portions with external apparatus.
摘要翻译： 适于安装在离心机中的可旋转处理碗组件包括由多个单独的柔性管形成的脐带管系统，每个柔性管各自与加工碗连通。 每个管具有外壁并且包括从碗相邻延伸的第一部分和与碗间隔开的第二部分。 管的外壁沿其第一部分结合在一起，使得连接的外壁沿着管的第一部分共同限定管道系统的外周。 优选地，管也被缠绕以沿其第一部分形成预定的螺旋形图案。 这种布置提高了管道系统的耐久性和耐疲劳性，特别是在更高的转速下，并且允许将自由和未附接的第二部分与外部设备直接，容易地连接。
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