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公开(公告)号：US20050063919A1
公开(公告)日：2005-03-24
申请号：US10665711
申请日：2003-09-19
申请人： Han Chang , Dominique Charmot , David Duncalf , Oleg Kolosov , Victor Nava-Salgado , Son Nguyen , Miroslav Petro , Steven Rannard
发明人： Han Chang , Dominique Charmot , David Duncalf , Oleg Kolosov , Victor Nava-Salgado , Son Nguyen , Miroslav Petro , Steven Rannard
CPC分类号： A61Q11/00 , A61K8/8152 , A61K8/8158 , A61K8/8164
摘要： Oral care composition comprising a polymer obtainable by copolymerising a mixture of comonomers, from 5 to 95 mol % of the mixture of comonomers is constituted by a comonomer having the formula (I): H2C═C(R)-L-(CH2)n-Y (I)in which R is hydrogen or a methyl group, L is a divalent organic linking group incorporating a benzyl or a carboxyl functionality, n is an integer of from 1 to 4 and Y is an amine, quaternized amine or quaternary ammonium group; and in which the balance of the mixture of comonomers is constituted by neutral and/or anionic comonomers; said composition being in the form of any one of a toothpaste, gel, foam, chewing gum, deformable strip or mouthwash and being suitable for use in the oral cavity.
摘要翻译： 含有共聚单体混合物（5〜95摩尔％的共聚单体混合物）的口腔护理组合物由具有式（I）的共聚单体构成：H2C = C（R）-L-（CH2）nY （I）其中R是氢或甲基，L是包含苄基或羧基官能团的二价有机连接基团，n是1至4的整数，Y是胺，季铵化胺或季铵基团; 其中共聚单体混合物的平衡由中性和/或阴离子共聚单体构成; 所述组合物为牙膏，凝胶，泡沫，口香糖，可变形条或漱口剂中任一种的形式，并且适合用于口腔。
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公开(公告)号：US20050063920A1
公开(公告)日：2005-03-24
申请号：US10666487
申请日：2003-09-19
申请人： Han Chang , Dominique Charmot , David Duncalf , Oleg Kolosov , Victor Nava-Salgado , Son Nguyen , Miroslav Petro , Steven Rannard
发明人： Han Chang , Dominique Charmot , David Duncalf , Oleg Kolosov , Victor Nava-Salgado , Son Nguyen , Miroslav Petro , Steven Rannard
CPC分类号： A61K8/8158 , A61K8/86 , A61K2800/5426 , A61Q11/00
摘要： Oral care composition comprising a cationic polymer obtainable by copolymerising a mixture of comonomers, said mixture comprising (ar-vinylbenzyl) trimethylammonium chloride, 2-acrylamido-2-methyl-1-propanesulfonic acid and polyethyleneglycol methylethermethacrylate, said composition being in the form of any one of a toothpaste, gel, foam, chewing gum, deformable strip or mouthwash and being suitable for use in the oral cavity.
摘要翻译： 包含阳离子聚合物的口腔护理组合物，所述阳离子聚合物可通过使共聚单体的混合物共聚获得，所述混合物包含（芳基苄基）三甲基氯化铵，2-丙烯酰胺基-2-甲基-1-丙磺酸和聚乙二醇甲基醚甲基丙烯酸酯，所述组合物为任何形式 牙膏，凝胶，泡沫，口香糖，可变形条或漱口水之一，适用于口腔。
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公开(公告)号：US20050063921A1
公开(公告)日：2005-03-24
申请号：US10666489
申请日：2003-09-19
申请人： Dominique Charmot , Christopher Gibbs , Oleg Kolosov , Mingjun Liu , Son Nguyen , Miroslav Petro , Steven Rannard
发明人： Dominique Charmot , Christopher Gibbs , Oleg Kolosov , Mingjun Liu , Son Nguyen , Miroslav Petro , Steven Rannard
CPC分类号： A61Q11/00 , A61K8/8158
摘要： Oral care composition comprising a polymer obtainable by copolymerising a mixture of comonomers, said mixture comprising: (a) a cationic monomer selected from (ar-vinylbenzyl) trimethylammonium chloride, (dimethylaminopropyl) methacrylamide, [2(methacryloyloxy)ethyl]trimethylammonium chloride, 2-aminoethylmethacrylate hydrochloride and mixtures thereof; and (b) at least one anionic or neutral monomer selected from styrene, mono-2-(methacryloyl)ethyl succinate, vinyl acetate, N, N-dimethylacrylamide, 2-ethylhexylacrylate, vinylphosphonic acid, acrylic acid, 2-acrylamido-2-methyl-1-propanesulfonic acid, N-[tris(hydroxymethyl)methyl] acrylamide, N-vinylpyrrolidone, butyl acrylate, 2-hydroxyethylacrylate, polyethyleneglycol methylethermethacrylate and mixtures thereof, said oral care composition in the form of any one of a toothpaste, gel, foam, chewing gum, deformable strip or mouthwash and which is suitable for use in the oral cavity.
摘要翻译： 所述混合物包含：（a）阳离子单体，选自（芳基乙烯基苄基）三甲基氯化铵，（二甲基氨基丙基）甲基丙烯酰胺，[2（甲基丙烯酰氧基）乙基]三甲基氯化铵，2 甲基丙烯酸氨基乙酯盐酸盐及其混合物; 和（b）至少一种阴离子或中性单体，其选自苯乙烯，琥珀酸单-2-（甲基丙烯酰）乙酯，乙酸乙烯酯，N，N-二甲基丙烯酰胺，丙烯酸2-乙基己酯，乙烯基膦酸，丙烯酸，2-丙烯酰胺基-2- 甲基-1-丙磺酸，N- [三（羟甲基）甲基]丙烯酰胺，N-乙烯基吡咯烷酮，丙烯酸丁酯，丙烯酸2-羟乙酯，聚乙二醇甲基醚甲基丙烯酸酯及其混合物，所述口腔护理组合物为牙膏，凝胶 ，泡沫，口香糖，可变形条或漱口水，适用于口腔。
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公开(公告)号：US20050063918A1
公开(公告)日：2005-03-24
申请号：US10665710
申请日：2003-09-19
申请人： Dominique Charmot , Christopher Gibbs , Oleg Kolosov , Mingjun Liu , Son Nguyen , Miroslav Petro , Steven Rannard
发明人： Dominique Charmot , Christopher Gibbs , Oleg Kolosov , Mingjun Liu , Son Nguyen , Miroslav Petro , Steven Rannard
CPC分类号： A61K8/8158 , A61K8/8152 , A61Q11/00
摘要： Oral care composition comprising a polymer obtainable by copolymerising a mixture of comonomers, in which at least 40 mol % of the mixture of comonomers is constituted by a comonomer having the formula (I): H2C═C(R)—(X)n—Yin which R is hydrogen or a methyl group, X is a divalent organic linking group, n is an integer of 0 or 1, and Y is a carboxylate or phosphonate anion, or the corresponding salt or acid thereof; and in which the balance of the mixture of comonomers is constituted by neutral and/or cationic comonomers; said composition being in the form of any one of a toothpaste, gel, foam, chewing gum, deformable strip or mouthwash and being suitable for use in the oral cavity.
摘要翻译： 口腔护理组合物包含可通过共聚合共聚单体混合物获得的聚合物，其中至少40摩尔％的共聚单体混合物由具有式（I）的共聚单体构成：H 2 C = C（R） - （X） 其中R为氢或甲基，X为二价有机连接基团，n为0或1的整数，Y为羧酸根或膦酸根阴离子，或其相应的盐或酸; 并且其中共聚单体混合物的平衡由中性和/或阳离子共聚单体构成; 所述组合物为牙膏，凝胶，泡沫，口香糖，可变形条或漱口剂中任一种的形式，并且适合用于口腔。
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5.发明授权Flow detectors having mechanical oscillators, and use thereof in flow characterization systems 有权具有机械振荡器的流量检测器及其在流动表征系统中的应用公开(公告)号：US07302830B2
公开(公告)日：2007-12-04
申请号：US10163064
申请日：2002-06-05
申请人： Oleg Kolosov , Leonid Matsiev , Miroslav Petro
发明人： Oleg Kolosov , Leonid Matsiev , Miroslav Petro
IPC分类号： G01N30/00
CPC分类号： G01N29/4427 , G01N9/002 , G01N9/32 , G01N11/167 , G01N29/022 , G01N29/036 , G01N29/348 , G01N29/46 , G01N30/16 , G01N30/76 , G01N35/085 , G01N2291/0256 , G01N2291/02818 , G01N2291/0422 , G01N2291/0423 , G01N2291/0426 , G01N2291/0427 , G01N2030/765
摘要： An improved system, device and method for characterizing a fluid sample that includes injecting a fluid sample into a mobile phase of a flow characterization system, and detecting a property of the fluid sample or of a component thereof with a flow detector comprising a mechanical resonator, preferably one that is operated at a frequency less than about 1 MHz, such as a tuning fork resonator.
摘要翻译： 一种用于表征流体样品的改进的系统，装置和方法，其包括将流体样品注入到流动表征系统的流动相中，以及用包括机械共振器的流动检测器检测流体样品或其组分的性质， 优选以小于约1MHz的频率操作的音调，例如音叉谐振器。
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公开(公告)号：US07259217B2
公开(公告)日：2007-08-21
申请号：US10775672
申请日：2004-02-10
IPC分类号： C08F120/54
CPC分类号： C08F20/54 , C08F2/38 , C08F4/00 , C08F220/54 , G01N27/44747
摘要： Controlled architecture polymers made preferably with acrylamide type monomers are prepared in living-type or semi-living-type free radical polymerizations, with the architecture preferably being other than linear, such as star, branched, grafted or hyper-branched. The controlled architecture polymers have high weight average molecular weights and low viscosities, which make they particularly useful in replaceable capillary electrophoresis separation media for biological molecules, such as DNA fragments.
摘要翻译： 在活性型或半活性型自由基聚合中制备优选用丙烯酰胺型单体制备的受控结构聚合物，其结构优选不是直链的，如星形，支链，接枝或超分支。 受控结构聚合物具有高重均分子量和低粘度，这使得它们特别适用于生物分子例如DNA片段的可更换毛细管电泳分离介质。
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公开(公告)号：US20060128917A1
公开(公告)日：2006-06-15
申请号：US10775672
申请日：2004-02-10
IPC分类号： C08F120/54
CPC分类号： C08F20/54 , C08F2/38 , C08F4/00 , C08F220/54 , G01N27/44747
摘要： Controlled architecture polymers made preferably with acrylamide type monomers are prepared in living-type or semi-living-type free radical polymerizations, with the architecture preferably being other than linear, such as star, branched, grafted or hyper-branched. The controlled architecture polymers have high weight average molecular weights and low viscosities, which make they particularly useful in replaceable capillary electrophoresis separation media for biological molecules, such as DNA fragments.
摘要翻译： 在活性型或半活性型自由基聚合中制备优选用丙烯酰胺型单体制备的受控结构聚合物，其结构优选不是直链的，如星形，支链，接枝或超分支。 受控结构聚合物具有高重均分子量和低粘度，这使得它们特别适用于生物分子例如DNA片段的可更换毛细管电泳分离介质。
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公开(公告)号：US06716948B1
公开(公告)日：2004-04-06
申请号：US09630328
申请日：2000-07-31
IPC分类号： C08F12054
CPC分类号： C08F20/54 , C08F2/38 , C08F4/00 , C08F220/54 , G01N27/44747
摘要： Controlled architecture polymers made preferably with acrylamide type monomers are prepared in living-type or semi-living-type free radical polymerizations, with the architecture preferably being other than linear, such as star, branched, grafted or hyper-branched. The controlled architecture polymers have high weight average molecular weights and low viscosities, which make they particularly useful in replaceable capillary electrophoresis separation media for biological molecules, such as DNA fragments.
摘要翻译： 在活性型或半活性型自由基聚合中制备优选用丙烯酰胺型单体制备的受控结构聚合物，其结构优选不是直链的，如星形，支链，接枝或超分支。 受控结构聚合物具有高重均分子量和低粘度，这使得它们特别适用于生物分子例如DNA片段的可更换毛细管电泳分离介质。
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公开(公告)号：US20060144171A1
公开(公告)日：2006-07-06
申请号：US11331719
申请日：2006-01-12
申请人： Eric Carlson , Miroslav Petro , Son Nguyen
发明人： Eric Carlson , Miroslav Petro , Son Nguyen
IPC分类号： G01N33/00
CPC分类号： C40B40/04 , G01N33/15 , Y10T436/119163 , Y10T436/255
摘要： Methods and systems for determining a dissolution profile of a sample material, and for solubilization screening of a library defined by an array comprising multiple sample materials are disclosed. The methods and systems are particularly advantageous for sampling and evaluation of very small samples, and can be advantageously applied in connection with evaluation of drug candidates.
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10.发明授权公开(公告)号：US08864996B2
公开(公告)日：2014-10-21
申请号：US11980156
申请日：2007-10-30
申请人： Daniel P. Leta , Edward W. Corcoran , Brian Erik Henry , James D. Dearth , Kirk C. Nadler , Stephen M. Cundy , Miroslav Petro , Thomas H. McWaid , Li Song , Yan Ying Chan
发明人： Daniel P. Leta , Edward W. Corcoran , Brian Erik Henry , James D. Dearth , Kirk C. Nadler , Stephen M. Cundy , Miroslav Petro , Thomas H. McWaid , Li Song , Yan Ying Chan
IPC分类号： C07C7/144 , B01D61/22 , B01D61/14 , B01D71/36 , B01D71/56 , C10G31/11 , B01D71/02 , B01D71/06
CPC分类号： B01D61/145 , B01D71/36 , B01D71/56 , B01D2221/04 , B01D2257/702 , B01D2325/02 , C10G31/11
摘要： This invention relates to a process for producing a product stream with improved reduction of Conradson Carbon Residue (“CCR”) and a reduced average boiling point from a heavy hydrocarbon feedstream utilizing a high-pressure, low-energy separation process. The invention may be utilized to reduce the CCR content and reduce the average boiling point in heavy hydrocarbon feedstreams, such as whole crudes, topped crudes, synthetic crude blends, shale oils, bitumen, oil from tar sands, atmospheric resids, vacuum resids, or other heavy hydrocarbon streams. This invention also results in a process with an improved CCR separation efficiency while maintaining permeate flux rates.
摘要翻译： 本发明涉及利用高压，低能分离方法，改善Conradson碳残余物（“CCR”）的还原性和从重烃进料流中降低的平均沸点来生产产物流的方法。 本发明可以用于减少CCR含量并降低重烃进料流中的平均沸点，例如整个原油，顶部原油，合成粗混合物，页岩油，沥青，来自焦油砂的油，常压渣油，减压渣油或 其他重质烃流。 本发明还导致具有改善的CCR分离效率同时保持渗透通量速率的方法。
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