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    Novel substituted hydroxyalkyl-azole antimycotic agents
    3.
    发明授权
    Novel substituted hydroxyalkyl-azole antimycotic agents 失效
    新型取代的羟烷基 - 唑类抗真菌剂

    公开(公告)号：US4806559A

    公开(公告)日：1989-02-21

    申请号：US757033

    申请日：1985-07-18

    申请人： Hans-Ludwig Elbe ,  Jorg Stetter ,  Karl H. Buchel ,  Klaus Schaller ,  Manfred Plempel

    发明人： Hans-Ludwig Elbe ,  Jorg Stetter ,  Karl H. Buchel ,  Klaus Schaller ,  Manfred Plempel

    IPC分类号： A61K31/41 ,  A61K31/415 ,  A61P31/04 ,  C07D233/60 ,  C07D233/64 ,  C07D249/08 ,  C07D303/22 ,  C07D521/00 ,  A01N43/64

    CPC分类号： C07D303/22 ,  C07D231/12 ,  C07D233/56 ,  C07D249/08

    摘要： An antimycotic agent, comprising a compound of the formula ##STR1## in which R.sup.1 is hydrogen, alkyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.2 is hydrogen, alkyl, alkenyl, alkynyl, optionally substituted phenyl or optionally substituted benzyl,R.sup.3 and Y each independently is halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenoxyalkyl,R.sup.4 and R.sup.5 each independently is alkyl,X is a nitrogen atom or the CH group,m is 0, 1, 2 or 3,n is 1 or 2, andp is 0, 1 or 2,or an acid addition salt thereof.

    摘要翻译： 一种抗真菌剂，其包含其中R 1为氢，烷基，任选取代的苯基或任选取代的苄基的式“IMAGE”化合物，R 2为氢，烷基，烯基，炔基，任选取代的苯基或任选取代的苄基，R 3和Y 各自独立地是卤素，烷基，环烷基，烷氧基，烷硫基，卤代烷基，卤代烷氧基，卤代烷硫基，任选取代的苯基，任选取代的苯氧基，任选取代的苯基烷基或任选取代的苯氧基烷基，R 4和R 5各自独立地是烷基，X是氮原子或 CH基，m为0,1,2或3，n为1或2，p为0,1或2，或其酸加成盐。