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1.发明授权Rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of fermenting to produce fumaric acid 有权米根霉菌株，其诱变和筛选方法以及发酵产生富马酸的方法公开(公告)号：US08663972B2
公开(公告)日：2014-03-04
申请号：US13992233
申请日：2011-04-16
摘要： A rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of producing fumaric acid by fermentation. The strain is named as Rhizopus oryzae ME-F13, and deposited in China Center for Type Culture Collection with depository number CCTCC M 2010351. The strain is obtained by physically mutagenizing the original strain ME-F12 through ion injection, culturing the processed bacteria on the solid selective plate containing 2-D-deoxylucose (2-DG) and picking up 2-DG-resistant single colony. The strain is capable of simultaneously saccharifying starchy material and fermenting it to produce fumaric acid. With an improved enzymatic activity, the strain can be directly used to ferment raw starchy materials without needing pre-saccharifying.
摘要翻译： 根霉菌株，其诱变和筛选方法，以及通过发酵产生富马酸的方法。 该菌株被命名为米曲霉ME-F13，并存放于中国型号培养基中心，存放号码为CCTCC M 2010351.该菌株是通过离子注射物理诱变原始菌株ME-F12获得的， 含有2-D脱氧葡萄糖（2-DG）的固体选择性板和拾取2-DG抗性单个菌落。 该菌株能够同时糖化淀粉物质并发酵以产生富马酸。 具有改善的酶活性，该菌株可以直接用于发酵生淀粉材料，而不需要预糖化。
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2.发明申请RHIZOPUS ORYZAE STRAIN, MUTAGENESIS AND SCREENING METHODS THEREOF, AND METHODS OF FERMENTING TO PRODUCE FUMARIC ACID 有权红霉素ORYZAE菌株，MUTAGENESIS和筛选方法及其生产方法公开(公告)号：US20140004560A1
公开(公告)日：2014-01-02
申请号：US13992233
申请日：2011-04-16
IPC分类号： C12P7/46
摘要： A rhizopus oryzae strain, mutagenesis and screening methods thereof, and methods of producing fumaric acid by fermentation. The strain is named as Rhizopus oryzae ME-F13, and deposited in China Center for Type Culture Collection with depository number CCTCC M 2010351. The strain is obtained by physically mutagenizing the original strain ME-F12 through ion injection, culturing the processed bacteria on the solid selective plate containing 2-D-deoxylucose (2-DG) and picking up 2-DG-resistant single colony. The strain is capable of simultaneously saccharifying starchy material and fermenting it to produce fumaric acid. With an improved enzymatic activity, the strain can be directly used to ferment raw starchy materials without needing pre-saccharifying.
摘要翻译： 根霉菌株，其诱变和筛选方法，以及通过发酵产生富马酸的方法。 该菌株被命名为米曲霉ME-F13，并存放于中国型号培养基中心，存放号码为CCTCC M 2010351.该菌株是通过离子注射物理诱变原始菌株ME-F12获得的， 含有2-D脱氧葡萄糖（2-DG）的固体选择性板和拾取2-DG抗性单个菌落。 该菌株能够同时糖化淀粉物质并将其发酵以产生富马酸。 具有改善的酶活性，该菌株可以直接用于发酵生淀粉材料，而不需要预糖化。
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公开(公告)号：US10152650B2
公开(公告)日：2018-12-11
申请号：US15557449
申请日：2016-03-08
申请人： Qing Xu
发明人： Qing Xu
摘要： A trademark retrieval method, comprising: establishing a sample trademark library and establishing a correlation between sample trademarks and division data for figurative element codes of known pending or registered figurative trademarks; extracting and processing image feature information about the sample trademarks, and establishing a correlation between the sample trademarks and the extracted image feature information; extracting image feature information about a trademark to be retrieved; carrying out matching retrieval by taking the image feature information as a retrieval condition, and finding out a sample trademark reaching a pre-determined similarity degree, and a sample trademark with the highest similarity degree and a corresponding figurative element code; acquiring and confirming a figurative element code of the trademark to be retrieved; taking the figurative element code as a retrieval condition to carry out matching retrieval, and finding out a matching sample trademark; collecting a result retrieved by taking the image feature information as the retrieval condition and a result retrieved by taking the figurative element code as the retrieval condition; and sequencing the collected trademarks according to the similarity degree of the image feature information. By means of the present disclosure, the standardized retrieval of figurative trademarks can be realized.
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4.发明申请公开(公告)号：US20140016946A1
公开(公告)日：2014-01-16
申请号：US13545193
申请日：2012-07-10
申请人： Qing Xu , Robert Brunner , Stephane Lessard
发明人： Qing Xu , Robert Brunner , Stephane Lessard
CPC分类号： G02B27/1006 , H04J14/02 , H04J14/0221
摘要： A chassis includes a plurality of continuous wave lasers each operable to emit a continuous wave optical beam at the same power as the other lasers, and a plurality of optical couplers operable to input the continuous wave optical beams of the same power and output a plurality of continuous wave optical beams at different powers. The chassis further includes a plurality of optical assemblies operable to modulate the continuous wave optical beams of different powers into a plurality of modulated optical signals at different powers and couple the modulated optical signals onto different length optical mediums so that lower power ones of the modulated optical signals are coupled to shorter ones of the optical mediums and higher power ones of the modulated optical signals are coupled to longer ones of the optical mediums.
摘要翻译： 底架包括多个连续波激光器，每个连续波激光器可操作以以与其它激光器相同的功率发射连续波光束;以及多个光耦合器，其可操作以输入相同功率的连续波光束并输出多个 连续波光束在不同功率下。 底盘还包括多个光学组件，其可操作以将不同功率的连续波光束调制成不同功率的多个调制光信号，并将调制的光信号耦合到不同长度的光介质上，使得调制光 信号耦合到较短的光介质，并且较高功率的调制光信号耦合到更长的光介质。
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5.发明授权公开(公告)号：US08440473B2
公开(公告)日：2013-05-14
申请号：US13154075
申请日：2011-06-06
IPC分类号： H01L21/00
CPC分类号： H01L21/30655 , H01J37/32972
摘要： A method for etching features into an etch layer in a plasma processing chamber is provided. An optically timed deposition phase is provided comprising providing a flow of deposition phase gas, detecting the presence of deposition gas within the plasma processing chamber, providing RF energy for forming a plasma from the deposition phase gas in the plasma processing chamber, and stopping the flow of the deposition gas into the plasma processing chamber. An optically timed etching phase is provided, comprising providing a flow of an etch gas, detecting the presence of the etch gas within the plasma processing chamber, providing RF energy for forming a plasma from the etch gas in the plasma processing chamber, and stopping the flow of the etch gas into the plasma processing chamber.
摘要翻译： 提供了一种用于将特征蚀刻到等离子体处理室中的蚀刻层中的方法。 提供了一种光学定时沉积阶段，包括提供沉积相气体流，检测等离子体处理室内的沉积气体的存在，提供用于从等离子体处理室中的沉积相气体形成等离子体的RF能量，并停止流动 的沉积气体进入等离子体处理室。 提供光学定时的蚀刻阶段，包括提供蚀刻气体流，检测等离子体处理室内的蚀刻气体的存在，提供用于从等离子体处理室中的蚀刻气体形成等离子体的RF能量，并停止 蚀刻气体流入等离子体处理室。
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公开(公告)号：US08063058B2
公开(公告)日：2011-11-22
申请号：US12386525
申请日：2009-04-16
申请人： Zhaozhong J. Jia , Chandrasekar Venkataramani , Wolin Huang , Mukund Mehrotra , Yonghong Song , Qing Xu , Shawn M. Bauer , Jack W. Rose , Brian Kane , Anjali Pandey
发明人： Zhaozhong J. Jia , Chandrasekar Venkataramani , Wolin Huang , Mukund Mehrotra , Yonghong Song , Qing Xu , Shawn M. Bauer , Jack W. Rose , Brian Kane , Anjali Pandey
IPC分类号： A01N43/54 , A61K31/505 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D411/00 , C07D413/00 , C07D417/00 , C07D419/00
CPC分类号： A61K31/506 , C07D239/48 , C07D401/12 , C07D403/12 , C07D407/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
摘要翻译： 本发明涉及作为syk激酶抑制剂的式I-V化合物及其互变异构体或其药学上可接受的盐，酯和前体药物。 本发明还涉及用于制备这种化合物的中间体，这种化合物的制备，含有这种化合物的药物组合物，抑制syk激酶活性的方法，抑制血小板聚集的方法，以及预防或治疗数字的方法 至少部分通过syk激酶活性介导的病症，例如不期望的血栓形成和非霍奇金淋巴瘤。
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7.发明授权Type II restriction endonuclease, HpyCH4IV, obtainable from Helicobacter pylori CH4 and a process for producing the same 有权可从幽门螺杆菌CH4获得的II型限制性内切核酸酶HpyCH4IV及其制备方法公开(公告)号：US06194188B1
公开(公告)日：2001-02-27
申请号：US09404671
申请日：1999-09-23
申请人： Richard D. Morgan , Qing Xu
发明人： Richard D. Morgan , Qing Xu
IPC分类号： C12N922
CPC分类号： C12N9/22 , C12N9/1007 , Y10S530/825
摘要： In accordance with the present invention, there is provided a novel restriction endonuclease and its DNA obtainable from Helicobacter pylori CH4 (NEB#1236), hereinafter referred to as “HpyCH4IV”, which endonuclease: (1) recognizes the nucleotide sequence 5′-ACGT-3′ to in a double-stranded DNA molecule as shown below, 5′-A↓CGT-3′ 3′-TGC↑A-5′ (wherein G represents guanine, C represents cytosine, A represents adenine, T represents thymine and N represents either G, C, A, or T); (2) cleaves said sequence in the phosphodiester bonds between the A and C as indicated with the arrows; and (3) cleaves double-stranded PhiX174 DNA to produce 19 fragments, including fragments of 1036, 749, 397, 379, 371, 365, 362, 343, 282, 282, 268 base pairs, and 8 fragments smaller than 200 base pairs.
摘要翻译： 根据本发明，提供了一种新的限制性内切核酸酶及其可从幽门螺杆菌CH4（NEB＃1236）获得的DNA，以下称为“HpyCH4IV”，该内切核酸酶：（1）识别核苷酸序列5'-ACGT -3'到如下所示的双链DNA分子中，5'-A↓CGT-3'3'-TGC↑A-5'（其中G表示鸟嘌呤，C表示胞嘧啶，A表示腺嘌呤，T表示胸腺嘧啶 并且N表示G，C，A或T）;（2）如箭头所示切割A和C之间的磷酸二酯键中的所述序列; 并且（3）切割双链PhiX174DNA以产生19个片段，包括1036,749,397,397,371,365,362,343,282,282,268碱基对和小于200个碱基对的8个片段的片段 。
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8.发明授权Wavelength based optical power positioning for information and communications technology systems 有权用于信息和通信技术系统的基于波长的光功率定位公开(公告)号：US09002206B2
公开(公告)日：2015-04-07
申请号：US13545200
申请日：2012-07-10
申请人： Qing Xu , Robert Brunner , Stephane Lessard
发明人： Qing Xu , Robert Brunner , Stephane Lessard
IPC分类号： H04B10/564 , H04B10/50 , H04B10/80 , H04J14/02
CPC分类号： H04B10/801 , H04J14/02 , H04J14/0221
摘要： Wavelength-based optical power provisioning is provided by multiplexing a plurality of continuous wave light beams at different wavelengths onto a single optical fiber as a multiplexed light source and demultiplexing the multiplexed light source based on wavelength at a photonic unit coupled to the optical fiber to recover the continuous wave light beams. The recovered continuous wave light beams are split into a plurality of light beams by the photonic unit, each light beam having the same wavelength and the same or lower power as one of the recovered continuous wave light beams so that at least one of the light beams generated by the photonic unit has a higher power than the other light beams generated by the photonic unit.
摘要翻译： 基于波长的光功率供给通过将多个不同波长的连续波光束多路复用到作为复用光源的单个光纤上并且基于耦合到光纤的光子单元的波长来解复用多路复用光源来恢复 连续波光束。 回收的连续波束通过光子单元被分成多个光束，每个光束具有与恢复的连续波束光束之一相同的波长和相同或更低的功率，使得至少一个光束 由光子单元生成的光功率比由光子单元产生的其它光束具有更高的功率。
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公开(公告)号：US08859744B2
公开(公告)日：2014-10-14
申请号：US12445929
申请日：2007-10-16
申请人： Qing Xu , Hamilton O. Smith
发明人： Qing Xu , Hamilton O. Smith
CPC分类号： C12P3/00 , C12N9/0067 , C12N13/00 , Y02P20/134
摘要： A recombinant cyanobacterium comprising an oxygen-tolerant, hydrogen-evolving hydrogenase, kit, and methods of use.
摘要翻译： 包含耐氧性，析氢氢化酶，试剂盒和使用方法的重组蓝细菌。
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10.发明授权Agile light source provisioning for information and communications technology systems 有权用于信息和通信技术系统的敏捷光源配置公开(公告)号：US08798472B2
公开(公告)日：2014-08-05
申请号：US13545193
申请日：2012-07-10
申请人： Qing Xu , Robert Brunner , Stephane Lessard
发明人： Qing Xu , Robert Brunner , Stephane Lessard
IPC分类号： H04B10/00
CPC分类号： G02B27/1006 , H04J14/02 , H04J14/0221
摘要： A chassis includes a plurality of continuous wave lasers each operable to emit a continuous wave optical beam at the same power as the other lasers, and a plurality of optical couplers operable to input the continuous wave optical beams of the same power and output a plurality of continuous wave optical beams at different powers. The chassis further includes a plurality of optical assemblies operable to modulate the continuous wave optical beams of different powers into a plurality of modulated optical signals at different powers and couple the modulated optical signals onto different length optical mediums so that lower power ones of the modulated optical signals are coupled to shorter ones of the optical mediums and higher power ones of the modulated optical signals are coupled to longer ones of the optical mediums.
摘要翻译： 底架包括多个连续波激光器，每个连续波激光器可操作以以与其它激光器相同的功率发射连续波光束;以及多个光耦合器，其可操作以输入相同功率的连续波光束并输出多个 连续波光束在不同功率下。 底盘还包括多个光学组件，其可操作以将不同功率的连续波光束调制成不同功率的多个调制光信号，并将调制的光信号耦合到不同长度的光介质上，使得调制光 信号耦合到较短的光介质，并且较高功率的调制光信号耦合到更长的光介质。
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