PROCESS FOR THE SYNTHESIS OF ALPHA-METHYLENE-GAMMA-BUTYROLACTONE

    公开(公告)号:US20240425890A1

    公开(公告)日:2024-12-26

    申请号:US18800537

    申请日:2024-08-12

    Abstract: The present application provides a process for the preparation of α-methylene-γ-butyrolactone, said process comprising the steps of: a) acetylating the C1-hydroxyl group of isoprenol to yield isoprenyl acetate; b) forming 4-acetoxy-2-methylene-butan-1-ol from said isoprenyl acetate by whole cell biotransformation, said step comprising: i) contacting a cell (CB) with a culture medium containing said isoprenyl acetate or with a culture medium contiguous with an organic phase containing said isoprenyl acetate under conditions that enable the cell to form 4-acetoxy-2-methylene-butan-1-ol from isoprenyl acetate; and, ii) optionally isolating the resultant 4-acetoxy-2-methylene-butan-1-ol, wherein said cell (CB) exhibits activity of at least one alkane monooxygenase enzyme which catalyzes the formation of 4-acetoxy-2-methylene-butan-1-ol from isoprenyl acetate; c) oxidizing said 4-acetoxy-2-methylene-butan-1-ol to yield 4-acetoxy-2-methylene butyric acid; and, d) converting said 4-acetoxy-2-methylene butyric acid to α-methylene-γ-butyrolactone by hydroxylysis to γ-hydroxy-α-methylenebutyric acid and subsequent cyclization of said γ-hydroxy-α-methylenebutyric acid.

    PEPTIDES THAT CAN BE USED IN COATING AGENTS, ADHESION PROMOTERS OR ADHESIVES FOR OXIDIC SURFACES
    5.
    发明申请
    PEPTIDES THAT CAN BE USED IN COATING AGENTS, ADHESION PROMOTERS OR ADHESIVES FOR OXIDIC SURFACES 审中-公开
    可用于涂料代理的胶粘剂,粘合剂促进剂或粘合剂用于氧化表面

    公开(公告)号:US20150259383A1

    公开(公告)日:2015-09-17

    申请号:US14705682

    申请日:2015-05-06

    CPC classification number: C07K7/08 G01N33/6839 G01N33/84 Y10T428/31768

    Abstract: The present invention relates to peptides, in particular dodecapeptide-containing coating agents, adhesion promoters or adhesives for oxidic surfaces, a multilayer composite or a coated substrate, containing compounds which are formed entirely or in part of dodecapeptides as adhesion promoters between at least two adjacent layers of the composite or between the coating and the substrate, and to dodecapeptides that can be used as coating agents, adhesion promoters or adhesives for oxidic surfaces.

    Abstract translation: 本发明涉及肽,特别是含十二肽的包衣剂,用于氧化表面的粘合促进剂或粘合剂,多层复合材料或涂层底物,其含有完全或部分由十二肽形成的化合物,作为至少两个相邻 复合材料层或涂层和基材之间的层,以及可用作涂覆剂的十二肽,用于氧化表面的粘合促进剂或粘合剂。

    Enzyme-containing mini-emulsions
    6.
    发明授权
    Enzyme-containing mini-emulsions 有权
    含酶微型乳液

    公开(公告)号:US08883465B2

    公开(公告)日:2014-11-11

    申请号:US13802862

    申请日:2013-03-14

    Abstract: The present invention relates to a mini-emulsion which comprises at least one hydrolase, where the continuous phase of the mini-emulsion contains at least one oxidant, while the dispersed phase comprises at least one C6-60 carboxylic acid and optionally at least one reactant. Furthermore, the present invention relates to a method of preparing the mini-emulsion and to a process for the preparation of C6-60 percarboxylic acids and to a process for the preparation of an oxidized reactant, in each case using the abovementioned mini-emulsions.

    Abstract translation: 本发明涉及一种微乳液,其包含至少一种水解酶,其中微乳液的连续相含有至少一种氧化剂,而分散相包含至少一种C6-60羧酸和任选的至少一种反应物 。 此外,本发明涉及制备微乳液的方法和制备C6-60过羧酸的方法以及制备氧化反应物的方法,每种情况都使用上述微型乳液。

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